Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[5-chloro-2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]anilino]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
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 PubChem ID
CID: 168282571
Canonical SMILES
OCC1CCN(Cc2ccc(Nc3ncc(Cl)c(OC4CCN(CC4)C(=O)C=C)n3)cc2)CC1
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Compound Formula C25H32ClN5O3
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 12.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 179.52 nM
   TI
   LI
   LO
   TS