Brief Information of the Compound and Protein
Compound Name
N-[1-(4-hydroxycyclohexyl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
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Canonical SMILES
O[C@H]1CC[C@@H](CC1)n1c(NC(=O)c2cccc(c2)C(F)(F)F)nc2ccccc12
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Compound Formula C21H20F3N3O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
2
IC50 = 2000 nM
   TI
   LI
   LO
   TS
3
IC50 > 50000 nM
   TI
   LI
   LO
   TS