Brief Information of the Compound and Protein
Compound Name
1-[4-[2-(2-methoxy-4-morpholin-4-ylanilino)thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
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PubChem ID
CID: 168273391
Canonical SMILES
COc1cc(ccc1Nc1nc(OC2CCN(CC2)C(=O)C=C)c2sccc2n1)N1CCOCC1
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Compound Formula C25H29N5O4S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 9.664 nM
   TI
   LI
   LO
   TS
2
IC50 = 246.21 nM
   TI
   LI
   LO
   TS