| Compound ID |
Compound Name |
Compound Formula |
|
CP0201838
|
(E)-N-(4-amino-2-tert-butylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C23H22F3N3O
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0110899
|
(E)-N-(4-amino-2-sec-butylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C23H22F3N3O
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0284832
|
(E)-N-(4-amino-2-cyclopentylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C24H22F3N3O
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0075750
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-(methylthio)phenyl)acrylamide
Show/Hide
|
C22H23N3OS
|
1
|
| 1 |
EC50 = 71 nM
|
|
|
|
CP0280413
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-p-tolylacrylamide
Show/Hide
|
C22H23N3O
|
1
|
| 1 |
EC50 = 71 nM
|
|
|
|
CP0330412
|
N-(4-amino-2-propylquinolin-6-yl)-4-(4-chlorophenyl)benzamide
Show/Hide
|
C25H22ClN3O
|
1
|
| 1 |
EC50 = 75 nM
|
|
|
|
CP0162629
|
(E)-N-(4-amino-2-pentylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C24H24F3N3O
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0330416
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-bromophenyl)acrylamide
Show/Hide
|
C21H20BrN3O
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0161875
|
(E)-N-(4-amino-2-cyclohexylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C25H24F3N3O
|
1
|
| 1 |
EC50 = 96 nM
|
|
|
|
CP0173364
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-chlorophenyl)acrylamide
Show/Hide
|
C21H20ClN3O
|
1
|
| 1 |
EC50 = 96 nM
|
|
|
|
CP0059631
|
(E)-N-(4-amino-2-neopentylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C24H24F3N3O
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0254959
|
(E)-N-(4-amino-2-ethylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C21H18F3N3O
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0312808
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(biphenyl-4-yl)acrylamide
Show/Hide
|
C27H25N3O
|
1
|
| 1 |
EC50 = 118 nM
|
|
|
|
CP0132422
|
N-(4-amino-2-propylquinolin-6-yl)-3-[4-(trifluoromethyl)phenyl]propanamide
Show/Hide
|
C22H22F3N3O
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0162626
|
(E)-N-(4-amino-2-methylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C20H16F3N3O
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0171429
|
(E)-N-(4-(methylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C23H22F3N3O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0110561
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-ethylphenyl)acrylamide
Show/Hide
|
C23H25N3O
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0110914
|
(E)-N-(4-amino-2-isopropylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C22H20F3N3O
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0110560
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-fluorophenyl)acrylamide
Show/Hide
|
C21H20FN3O
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0312799
|
(E)-N-(4-amino-2-butylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C23H22F3N3O
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0290535
|
(E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C23H20F3N3O
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0075749
|
(E)-N-(4-(cyclobutylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C26H26F3N3O
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0110907
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-iodophenyl)acrylamide
Show/Hide
|
C21H20IN3O
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0132425
|
(E)-N-(4-(dimethylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C24H24F3N3O
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0110908
|
N-(4-amino-2-propylquinolin-6-yl)-4-[4-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C26H22F3N3O
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0154854
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-nitrophenyl)acrylamide
Show/Hide
|
C21H20N4O3
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0173343
|
(E)-N-(4-(ethylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C24H24F3N3O
|
1
|
| 1 |
EC50 = 340 nM
|
|
|
|
CP0132424
|
(E)-N-(4-methoxy-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C23H21F3N2O2
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
|
CP0312798
|
N-(4-amino-2-propylquinolin-6-yl)-4-(4-chlorophenyl)cyclohexane-1-carboxamide
Show/Hide
|
C25H28ClN3O
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0075741
|
1-(4-amino-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)benzyl)urea
Show/Hide
|
C21H21F3N4O
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0173363
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(2-chlorophenyl)acrylamide
Show/Hide
|
C21H20ClN3O
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0285273
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-isopropylphenyl)acrylamide
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0173426
|
(E)-4-(3-(4-amino-2-propylquinolin-6-ylamino)-3-oxoprop-1-enyl)phenyl acetate
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0280414
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-butylphenyl)acrylamide
Show/Hide
|
C25H29N3O
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
|
CP0110562
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(2,4-dichlorophenyl)acrylamide
Show/Hide
|
C21H19Cl2N3O
|
1
|
| 1 |
EC50 = 904 nM
|
|
|
|
CP0173425
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-tert-butylphenyl)acrylamide
Show/Hide
|
C25H29N3O
|
1
|
| 1 |
EC50 = 910 nM
|
|
|
|
CP0337248
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(3,4-dichlorophenyl)acrylamide
Show/Hide
|
C21H19Cl2N3O
|
1
|
| 1 |
EC50 = 990 nM
|
|
|
|
CP0337249
|
2-propyl-N6-(3-(4-(trifluoromethyl)phenyl)propyl)quinoline-4,6-diamine
Show/Hide
|
C22H24F3N3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0195827
|
(E)-N-(4-(azetidin-1-yl)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C25H24F3N3O
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0341823
|
(E)-N-(2-propyl-4-(pyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C26H26F3N3O
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0202316
|
(E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-propylphenyl)acrylamide
Show/Hide
|
C24H27N3O
|
1
|
| 1 |
EC50 = 3600 nM
|
|
|
|
CP0291544
|
(E)-N-(4-amino-2-phenylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide
Show/Hide
|
C25H18F3N3O
|
1
|
| 1 |
EC50 = 6600 nM
|
|
|
|
CP0457565
|
(1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C22H27N3OS
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
|
CP0523203
|
1-(2-(4-fluoro-3-methylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(3-fluorophenyl)urea
Show/Hide
|
C27H28F2N4O3
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0124792
|
6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)thieno[3,2-d]pyrimidin-4(3H)-one
Show/Hide
|
C25H24ClN3O3S
|
2
|
| 1 |
IC50 = 0.5012 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0472052
|
N-[1-(6-oxo-1H-pyridin-3-yl)pentyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C29H35F3N4O2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 19 nM
|
|
|
|
CP0532398
|
1-(2-(3,4-difluorophenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(3-fluorophenyl)urea
Show/Hide
|
C26H25F3N4O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0497065
|
N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3,5-dimethoxybenzamide
Show/Hide
|
C25H31N5O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0376192
|
1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(p-tolyloxy)phenyl)-3-(3-fluorophenyl)urea
Show/Hide
|
C27H29FN4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0421357
|
1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(3-fluorophenyl)urea
Show/Hide
|
C28H31FN4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0541305
|
1-(5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)-2-(m-tolyloxy)phenyl)-3-(3-fluorophenyl)urea
Show/Hide
|
C27H29FN4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0454256
|
N-[(4-fluorophenyl)-(6-oxo-1H-pyridin-3-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H30F4N4O2
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
|
CP0506350
|
N-[(4-fluorophenyl)-(6-methoxypyridin-3-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C32H32F4N4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0374124
|
N-[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]-3,4-difluorobenzamide
Show/Hide
|
C20H25F2N5O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0500611
|
N-[4-[[4-(dimethylamino)-5,6-dimethylpyrimidin-2-yl]amino]cyclohexyl]-3,4-difluorobenzamide
Show/Hide
|
C21H27F2N5O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0500610
|
CHEMBL578166
Show/Hide
|
C20H25F2N5O
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0124082
|
N-[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]-3-methylbenzamide
Show/Hide
|
C21H29N5O
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0530319
|
(1S,3S)-N1-(6-methoxy-4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0043469
|
ATC0175
Show/Hide
|
C23H25F2N5O
|
2
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 7.2 nM
|
|
|
|
CP0499940
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-9H-xanthene-9-carboxamide
Show/Hide
|
C28H28F3N5O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0407598
|
N-[(4-fluorophenyl)methyl]-N-(3-hydroxypropyl)-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C29H33F4N3O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0461183
|
3,5-dichloro-N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)methyl)benzamide
Show/Hide
|
C21H27Cl2N5O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0431375
|
3-Chloro-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide
Show/Hide
|
C23H26ClN5O
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0404697
|
N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3-methylbenzamide
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0057005
|
3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)benzamide
Show/Hide
|
C20H25Cl2N5O
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0431371
|
2-N-[4-[[[4-bromo-2-(trifluoromethoxy)phenyl]methylamino]methyl]cyclohexyl]-4-N,4-N-dimethylquinazoline-2,4-diamine
Show/Hide
|
C25H29BrF3N5O
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0445994
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-9H-fluorene-9-carboxamide
Show/Hide
|
C28H28F3N5O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0452774
|
(1S,3S)-N1-((5-(difluoromethoxy)-1-methyl-1H-indol-3-yl)methyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclopentane-1,3-diamine
Show/Hide
|
C27H30F2N4O2
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0475855
|
3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide
Show/Hide
|
C23H25Cl2N5O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0456059
|
N-[1-(6-methoxypyridin-3-yl)pentyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C30H37F3N4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0071262
|
N-[[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]methyl]-3,5-bis(trifluoromethyl)benzamide
Show/Hide
|
C23H27F6N5O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0413189
|
4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide
Show/Hide
|
C26H27FN2O
|
2
|
| 1 |
IC50 = 5.5 nM
|
|
|
| 2 |
Ki = 5.5 nM
|
|
|
|
CP0449373
|
3-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide
Show/Hide
|
C23H26BrN5O
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0372478
|
N-[(5-chloro-6-oxo-1H-pyridin-3-yl)-(4-fluorophenyl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H29ClF4N4O2
|
2
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
IC50 = 21 nM
|
|
|
|
CP0124083
|
N-[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]-4-fluorobenzamide
Show/Hide
|
C20H26FN5O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0500608
|
3-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)benzamide
Show/Hide
|
C20H26ClN5O
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0424979
|
N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3-nitrobenzamide
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0467180
|
(1S,3S)-N1-(4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C21H25N3S
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 59 nM
|
|
|
|
CP0376182
|
1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-phenylurea
Show/Hide
|
C28H32N4O3
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
Ki = 4.7 nM
|
|
|
|
CP0508303
|
N-[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]cyclohexyl]-3-methoxybenzamide
Show/Hide
|
C21H29N5O2
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0565467
|
(1S,3S)-N1-(4-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
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C21H25N3OS
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2
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| 1 |
IC50 = 8 nM
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| 2 |
IC50 = 9 nM
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CP0407597
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N-[(2,4-dichlorophenyl)methyl]-4-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperazine-1-carboxamide
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C24H23Cl2F3N4O
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1
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| 1 |
IC50 = 8 nM
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CP0039847
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N-[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]cyclohexyl]-3,5-bis(trifluoromethyl)benzamide
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C22H25F6N5O
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1
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| 1 |
IC50 = 8 nM
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CP0457562
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(1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-((1-methyl-1H-indol-3-yl)methyl)cyclopentane-1,3-diamine
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C26H30N4O
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2
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| 1 |
IC50 = 9 nM
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| 2 |
IC50 = 85 nM
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CP0394662
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1-(2-(3-fluorophenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(3-fluorophenyl)urea
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C26H26F2N4O3
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1
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| 1 |
IC50 = 9 nM
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CP0378311
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N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-4-fluorobenzamide
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C23H26FN5O
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1
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| 1 |
IC50 = 9.4 nM
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CP0424928
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N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3-fluorobenzamide
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C23H26FN5O
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1
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| 1 |
IC50 = 9.5 nM
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CP0381111
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N-[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]cyclohexyl]-3-methylbenzamide
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C21H29N5O
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1
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| 1 |
IC50 = 9.6 nM
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CP0464529
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(1S,3S)-N1-(benzo[c][1,2,5]thiadiazol-4-ylmethyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
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C24H27N5OS
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1
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| 1 |
IC50 = 10 nM
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CP0392541
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3-Cyano-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide
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C24H26N6O
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1
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| 1 |
IC50 = 10 nM
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CP0192349
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1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide
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C31H32F3N5O
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1
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| 1 |
IC50 = 10 nM
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CP0057007
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4-chloro-N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)benzamide
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C20H26ClN5O
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1
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| 1 |
IC50 = 10 nM
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CP0464317
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1-(4-bromophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)urea
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C28H31BrN4O3
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1
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| 1 |
IC50 = 11 nM
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CP0254223
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1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C31H35F3N6O
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1
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| 1 |
IC50 = 11 nM
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CP0553070
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(1S,3S)-N1-(3,4-dichlorobenzyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
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C24H27Cl2N3O
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1
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| 1 |
IC50 = 13 nM
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CP0491749
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N-[bis(4-fluorophenyl)methyl]-2-[1-[[1-[5-(trifluoromethyl)pyridin-2-yl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
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C31H29F5N4O
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2
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| 1 |
IC50 = 13 nM
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| 2 |
IC50 = 17 nM
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CP0506011
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2-(4-fluorophenyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
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C28H30F4N4O
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1
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| 1 |
IC50 = 13 nM
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CP0057006
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N-[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]-4-methylbenzamide
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C21H29N5O
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1
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| 1 |
IC50 = 13 nM
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CP0192010
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6-(4-chlorophenyl)-3-[4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl]thieno[3,2-d]pyrimidin-4-one
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C23H21ClN2O4S
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2
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| 1 |
IC50 = 13 nM
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| 2 |
IC50 = 16 nM
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CP0464528
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6-methoxy-4-methyl-N-(3-(thiophen-3-ylmethylamino)propyl)quinolin-2-amine
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C19H23N3OS
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1
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| 1 |
IC50 = 15 nM
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CP0536165
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(1S,3S)-N1-(3-(trifluoromethoxy)benzyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
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C25H28F3N3O2
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1
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| 1 |
IC50 = 15 nM
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CP0496862
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N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3-(trifluoromethyl)benzamide
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C24H26F3N5O
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1
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| 1 |
IC50 = 15 nM
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CP0422198
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1-(2-chlorophenyl)-3-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)urea
Show/Hide
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C28H31ClN4O3
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1
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| 1 |
IC50 = 15 nM
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CP0474090
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2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
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C25H25ClF3N3O3
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2
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| 1 |
IC50 = 15 nM
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| 2 |
IC50 = 31 nM
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CP0452771
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(1S,3S)-N1-(benzo[c][1,2,5]thiadiazol-5-ylmethyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
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C24H27N5OS
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1
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| 1 |
IC50 = 16 nM
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CP0057003
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4-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)benzamide
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C20H26ClN5O
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1
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| 1 |
IC50 = 16 nM
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CP0472051
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N-[1H-imidazol-5-yl(phenyl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
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C29H30F3N5O
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1
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| 1 |
IC50 = 17 nM
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CP0535161
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N-[(4-chlorophenyl)-pyridin-4-ylmethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
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C31H30ClF3N4O
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1
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| 1 |
IC50 = 17 nM
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CP0208389
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1-(1-phenyl-2-(pyrazin-2-yl)ethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C30H31F3N6O
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1
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| 1 |
IC50 = 17 nM
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CP0452885
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1-(1-phenyl-2-(1H-pyrazol-1-yl)ethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C29H31F3N6O
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1
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| 1 |
IC50 = 19 nM
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CP0551280
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(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-1H-indole-2-carboxamide
Show/Hide
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C23H25F3N6O2
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1
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| 1 |
IC50 = 20 nM
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CP0452768
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3-(((1S,3S)-3-(7-methoxy-4-methylquinolin-2-ylamino)cyclopentylamino)methyl)-1-methyl-1H-indole-7-carbonitrile
Show/Hide
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C27H29N5O
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2
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 127 nM
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CP0434576
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4-(5-(4-fluorophenyl)-1H-imidazol-2-yl)-1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidine
Show/Hide
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C26H24F4N4
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2
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 122 nM
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CP0456058
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3-((4-fluorophenyl)(2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamido)methyl)pyridine 1-oxide
Show/Hide
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C31H30F4N4O2
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1
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| 1 |
IC50 = 21 nM
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CP0452884
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2-(pyridin-3-yl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
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C27H30F3N5O
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1
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| 1 |
IC50 = 21 nM
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CP0461705
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(1S,3S)-N1-(isoquinolin-4-ylmethyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
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C27H30N4O
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1
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| 1 |
IC50 = 22 nM
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CP0495572
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N-[(4-chloro-2-hydroxyphenyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
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C25H25ClF3N3O2
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1
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| 1 |
IC50 = 22 nM
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CP0510116
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3-(hydroxymethyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
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C24H31F3N4O2
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1
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| 1 |
IC50 = 23 nM
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CP0432696
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(R)-5-fluoro-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-1H-indole-2-carboxamide
Show/Hide
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C23H24F4N6O2
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1
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| 1 |
IC50 = 25 nM
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CP0457455
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(1S,3S)-N1-(6-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
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C21H25N3OS
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2
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| 1 |
IC50 = 25 nM
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| 2 |
IC50 = 57 nM
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CP0254230
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1-(2-(1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C29H31F3N6O
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1
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| 1 |
IC50 = 25 nM
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CP0500609
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CHEMBL568664
Show/Hide
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C20H26FN5O
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1
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| 1 |
IC50 = 25 nM
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CP0434575
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4-(5-(4-fluorophenyl)isoxazol-3-yl)-1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidine
Show/Hide
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C26H23F4N3O
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2
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| 1 |
IC50 = 25 nM
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| 2 |
IC50 = 67 nM
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CP0467178
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(1S,3S)-N1-(6-fluoro-4-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
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C21H24FN3OS
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2
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| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 90 nM
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CP0471501
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2-(pyridin-3-ylmethyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
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C28H32F3N5O
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1
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| 1 |
IC50 = 26 nM
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CP0415741
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N-[[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]methyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C22H28F3N5O
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1
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| 1 |
IC50 = 26 nM
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CP0440502
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5-methyl-4-phenyl-1-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1H-imidazol-2(3H)-one
Show/Hide
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C27H27F3N4O
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2
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| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 71 nM
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CP0367711
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1-((1H-imidazol-2-yl)(phenyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C28H29F3N6O
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1
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| 1 |
IC50 = 27 nM
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CP0464530
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(1S,3S)-N1-(2-bromo-5-methoxybenzyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
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C25H30BrN3O2
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1
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| 1 |
IC50 = 28 nM
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CP0407596
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N-[(4-fluorophenyl)-pyridin-3-ylmethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
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C31H30F4N4O
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1
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| 1 |
IC50 = 28 nM
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CP0506010
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4-methyl-2-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperazine-1-carboxamide
Show/Hide
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C29H34F3N5O
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1
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| 1 |
IC50 = 28 nM
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CP0522851
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(1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-((1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)methyl)cyclopentane-1,3-diamine
Show/Hide
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C25H29N5O
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2
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 83 nM
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CP0530320
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4-N,4-N-dimethyl-2-N-[(1S,3S)-3-(thiophen-3-ylmethylamino)cyclohexyl]quinoline-2,4-diamine
Show/Hide
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C22H28N4S
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2
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 97 nM
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CP0421443
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2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
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C25H25ClF3N3O2
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2
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 32 nM
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CP0501682
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2-(3,4-difluorophenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)pyrrolidin-3-yl)acetamide
Show/Hide
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C24H22F5N3O2
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2
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 48 nM
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CP0506083
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N-[(2-chloro-4-hydroxyphenyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
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C25H25ClF3N3O2
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1
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| 1 |
IC50 = 30 nM
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CP0457561
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3-(((1S,3S)-3-(7-methoxy-4-methylquinolin-2-ylamino)cyclopentylamino)methyl)-1-methyl-1H-indole-6-carbonitrile
Show/Hide
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C27H29N5O
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2
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| 1 |
IC50 = 33 nM
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| 2 |
IC50 = 118 nM
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CP0522852
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(1S,2S,4R,6S)-N2-(6-methoxy-4-methylquinolin-2-yl)-N6-(thiophen-3-ylmethyl)bicyclo[2.2.1]heptane-2,6-diamine
Show/Hide
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C23H27N3OS
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1
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| 1 |
IC50 = 35 nM
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CP0379328
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2-N-[4-[[4-bromo-2-(trifluoromethoxy)phenyl]methylamino]cyclohexyl]-4-N,4-N-dimethylquinazoline-2,4-diamine
Show/Hide
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C24H27BrF3N5O
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1
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| 1 |
IC50 = 35 nM
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CP0073203
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(S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C26H29F3N4O2
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1
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| 1 |
IC50 = 35 nM
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CP0473759
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4-(2-hydroxyphenyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
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C29H33F3N4O2
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1
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| 1 |
IC50 = 36 nM
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CP0407600
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N,N-diethyl-1-[2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetyl]piperidine-3-carboxamide
Show/Hide
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C29H39F3N4O2
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1
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| 1 |
IC50 = 37 nM
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CP0436160
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4-(5-(4-fluorophenyl)-1H-pyrazol-3-yl)-1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidine
Show/Hide
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C26H24F4N4
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2
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| 1 |
IC50 = 37 nM
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| 2 |
IC50 = 58 nM
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CP0480696
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N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-2,3,4-trifluorobenzamide
Show/Hide
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C23H24F3N5O
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1
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| 1 |
IC50 = 38 nM
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CP0208352
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1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C28H30F3N7O
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1
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| 1 |
IC50 = 38 nM
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CP0467177
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3-(((1S,3S)-3-(7-methoxy-4-methylquinolin-2-ylamino)cyclopentylamino)methyl)-1-methyl-1H-indole-5-carbonitrile
Show/Hide
|
C27H29N5O
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1
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| 1 |
IC50 = 39 nM
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CP0407602
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1-benzhydryl-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C31H31F3N4O
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1
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| 1 |
IC50 = 39 nM
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CP0429471
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2-(2-hydroxyethyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
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C25H33F3N4O2
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1
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| 1 |
IC50 = 39 nM
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CP0461046
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1-(3-fluorobenzyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C25H26F4N4O
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1
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| 1 |
IC50 = 39 nM
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CP0506347
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N-[(1-hydroxycyclohexyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
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C25H32F3N3O2
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1
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| 1 |
IC50 = 40 nM
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CP0473760
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3-(pyrrolidine-1-carbonyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
|
C28H36F3N5O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0535160
|
N-[phenyl(pyridin-2-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H31F3N4O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0500844
|
2-(3-chlorophenoxy)-N-(1-(naphthalen-2-ylmethyl)piperidin-4-yl)acetamide
Show/Hide
|
C24H25ClN2O2
|
2
|
| 1 |
IC50 = 41 nM
|
|
|
| 2 |
IC50 = 104 nM
|
|
|
|
CP0516412
|
(1S,3S)-N1-(5-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C21H25N3OS
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
IC50 = 54 nM
|
|
|
|
CP0436161
|
2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)azetidin-3-yl)acetamide
Show/Hide
|
C23H21ClF3N3O2
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
IC50 = 73 nM
|
|
|
|
CP0474088
|
2-(3-chlorophenoxy)-N-(1-(1-(1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)ethyl)piperidin-4-yl)acetamide
Show/Hide
|
C26H27ClF3N3O2
|
2
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 117 nM
|
|
|
|
CP0398527
|
1-((1-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C25H33F3N4O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0356452
|
6-(4-chlorophenyl)-3-[4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H22ClN3O4
|
2
|
| 1 |
IC50 = 44 nM
|
|
|
| 2 |
Ki = 2.3 nM
|
|
|
|
CP0562555
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C23H24F3N5O2S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0431389
|
1-(((1S,2R)-2-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C25H33F3N4O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0497116
|
CHEMBL568649
Show/Hide
|
C21H27F2N5O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0493266
|
2-(3-chlorophenoxy)-N-(1-((1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C24H24ClF3N4O2
|
2
|
| 1 |
IC50 = 48 nM
|
|
|
| 2 |
IC50 = 92 nM
|
|
|
|
CP0485355
|
3-(4-methoxyphenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)azetidine-1-carboxamide
Show/Hide
|
C28H31F3N4O3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0452770
|
(1S,3S)-N1-(2-chloro-4-(methylsulfonyl)benzyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
|
C25H30ClN3O3S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0423809
|
2-(3-chlorophenoxy)-N-(1-((1-(4-cyanophenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C25H25ClN4O2
|
2
|
| 1 |
IC50 = 52 nM
|
|
|
| 2 |
IC50 = 145 nM
|
|
|
|
CP0506346
|
N-[bis(4-fluorophenyl)methyl]-2-[4-[[1-[5-(trifluoromethyl)pyridin-2-yl]pyrrol-3-yl]methyl]piperazin-1-yl]acetamide
Show/Hide
|
C30H28F5N5O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0404742
|
1-((1-hydroxycyclohexyl)methyl)-1-methyl-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C26H35F3N4O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0457563
|
5-chloro-3-(((1S,3S)-3-(7-methoxy-4-methylquinolin-2-ylamino)cyclohexylamino)methyl)-N,N-dimethyl-1H-indole-1-carboxamide
Show/Hide
|
C29H34ClN5O2
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0488725
|
CHEMBL568209
Show/Hide
|
C21H28F2N6O
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0452772
|
(1S,3S)-N1-((5-bromo-1-methyl-1H-indol-3-yl)methyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
|
C27H31BrN4O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0453925
|
(1S,3S)-N1-(6-methoxy-4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclopentane-1,3-diamine
Show/Hide
|
C21H25N3OS
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0404745
|
1-(((1R,2R)-2-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C25H33F3N4O2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0485353
|
4-benzyl-4-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
|
C30H35F3N4O2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0461182
|
3,5-dichloro-N-(((cis)-4-(4-(dimethylamino)-6-methylpyrimidin-2-ylamino)cyclohexyl)methyl)benzamide
Show/Hide
|
C21H27Cl2N5O
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0456057
|
N-[2-(2-methylimidazol-1-yl)-1-phenylethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H34F3N5O
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0427238
|
1-(2-(pyrrolidine-1-carbonyl)piperidin-1-yl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
|
C29H37F3N4O2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0367712
|
1-(2-morpholino-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C30H36F3N5O2
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0500841
|
4-(3-(4-fluorophenyl)isoxazol-5-yl)-1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidine
Show/Hide
|
C26H23F4N3O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0534722
|
N-[1-(6-oxo-1H-pyridin-3-yl)ethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C26H29F3N4O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0536167
|
(1S,3S)-N1-(quinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C20H23N3S
|
2
|
| 1 |
IC50 = 68 nM
|
|
|
| 2 |
IC50 = 234 nM
|
|
|
|
CP0467230
|
(1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-((1-methyl-1H-pyrrolo[3,2-h]quinolin-3-yl)methyl)cyclopentane-1,3-diamine
Show/Hide
|
C29H31N5O
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0398984
|
1-(3-(pyrrolidine-1-carbonyl)piperidin-1-yl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
|
C29H37F3N4O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0357226
|
1-(2-(2-methyl-1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C30H33F3N6O
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0502752
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-5-methoxy-1H-indole-2-carboxamide
Show/Hide
|
C24H27F3N6O3
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0423808
|
2-(3-chlorophenoxy)-N-(1-((5-(4-(trifluoromethoxy)phenyl)furan-2-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C25H24ClF3N2O4
|
2
|
| 1 |
IC50 = 78 nM
|
|
|
| 2 |
IC50 = 103 nM
|
|
|
|
CP0436964
|
4-bromo-N-[[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]methyl]-2-(trifluoromethoxy)benzamide
Show/Hide
|
C25H27BrF3N5O2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0452769
|
(1S,3S)-N1-((5-(benzyloxy)-1-methyl-1H-indol-3-yl)methyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclopentane-1,3-diamine
Show/Hide
|
C33H36N4O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0500612
|
N-[[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]cyclohexyl]methyl]-3,5-difluorobenzamide
Show/Hide
|
C21H27F2N5O
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0485354
|
N-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]-3-[4-(trifluoromethyl)piperidin-1-yl]azetidine-1-carboxamide
Show/Hide
|
C27H33F6N5O
|
1
|
| 1 |
IC50 = 81.8 nM
|
|
|
|
CP0534807
|
1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-ylmethyl]-piperidin-4-yl}-urea
Show/Hide
|
C28H35F3N4O2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0554545
|
N-[1-[(6-chloro-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-2-(3-chlorophenoxy)acetamide
Show/Hide
|
C21H22Cl2N2O4
|
2
|
| 1 |
IC50 = 82 nM
|
|
|
| 2 |
IC50 = 505 nM
|
|
|
|
CP0392292
|
4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C23H25BrF3N5O3S
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0409351
|
4-Bromo-N-[4-(quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C21H20BrF3N4O3S
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0565535
|
(1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-(pyrazin-2-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C22H27N5O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0508158
|
1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C26H27F3N6O
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0490516
|
2-(3-chlorophenoxy)-N-(1-((1-(4-methoxyphenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C25H28ClN3O3
|
2
|
| 1 |
IC50 = 90 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0436155
|
N-[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]-5-nitrothiophene-3-carboxamide
Show/Hide
|
C17H17Cl2N3O3S
|
2
|
| 1 |
IC50 = 92 nM
|
|
|
| 2 |
IC50 = 804 nM
|
|
|
|
CP0514351
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)quinoline-3-carboxamide
Show/Hide
|
C24H25F3N6O2
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0422024
|
3-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-azetidine-1-carboxylic acid{1-[1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-ylmethyl]-piperidin-4-yl}-amide
Show/Hide
|
C25H32F3N5O3S
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0461180
|
N-[4-[[4-(dimethylamino)-5-ethylpyrimidin-2-yl]amino]cyclohexyl]-3,4-difluorobenzamide
Show/Hide
|
C21H27F2N5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0500843
|
2-(3,4-difluorophenoxy)-N-((1s,4s)-4-(1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-ylamino)cyclohexyl)acetamide
Show/Hide
|
C25H24F5N3O2
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0453924
|
N-[3-[(6-methoxy-4-methylquinolin-2-yl)amino]propyl]thiophene-3-carboxamide
Show/Hide
|
C19H21N3O2S
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
|
CP0474085
|
2-(3-chlorophenoxy)-N-methyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C26H27ClF3N3O2
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0485233
|
1-(4-chloro-2-(hydroxymethyl)phenyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0434574
|
2-(3-chlorophenoxy)-N-((1S,5R,6s)-3-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)-3-aza-bicyclo[3.1.0]hexan-6-yl)acetamide
Show/Hide
|
C25H23ClF3N3O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0560212
|
(R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-(trifluoromethyl)benzyl)pentanamide
Show/Hide
|
C28H30F3N5O2
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0229834
|
1-(1-(1H-imidazol-1-yl)-3-methylbutan-2-yl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C26H33F3N6O
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0554539
|
4-(2-(4-fluorophenyl)-1H-imidazol-5-yl)-1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidine
Show/Hide
|
C26H24F4N4
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0457566
|
(1S,3S)-N1-(6-methoxy-4-methylquinolin-2-yl)-N3-methyl-N3-(thiophen-3-ylmethyl)cyclopentane-1,3-diamine
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0452878
|
3-acetamido-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C24H30F3N5O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0233495
|
N-[[4-[[4-(dimethylamino)-5-methylpyrimidin-2-yl]amino]cyclohexyl]methyl]-3,4-difluorobenzamide
Show/Hide
|
C21H27F2N5O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0423810
|
2-(3-chlorophenoxy)-N-[1-[(4-pyridin-2-ylphenyl)methyl]piperidin-4-yl]acetamide
Show/Hide
|
C25H26ClN3O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0431390
|
(S)-3-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C22H27F3N4O2
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0404743
|
(R)-3-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C22H27F3N4O2
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0378340
|
4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C24H27BrF3N5O3S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0409350
|
4-Bromo-N-[4-(quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C22H22BrF3N4O3S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0404808
|
4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C25H29BrF3N5O3S
|
3
|
| 1 |
IC50 = 140 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
| 3 |
IC50 = 200 nM
|
|
|
|
CP0394648
|
3-(3-biphenyl-4-yl-ureido)-4-(3,4-dimethyl-phenoxy)-N-(2-pyrrolidin-1-yl-ethyl)-benzamide
Show/Hide
|
C34H36N4O3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0496554
|
N-methyl-N-(3-oxo-3-pyrrolidin-1-ylpropyl)-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C27H35F3N4O2
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0407595
|
N-[(2,4-dichloro-6-hydroxyphenyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C25H24Cl2F3N3O2
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0398983
|
2-(1-((5-(4-chlorophenyl)furan-2-yl)methyl)piperidin-4-yl)-N-(4-fluorobenzyl)-N-(2-hydroxy-3-methoxypropyl)acetamide
Show/Hide
|
C29H34ClFN2O4
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0135402
|
(R)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C26H29F3N4O2
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0392299
|
4-bromo-N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-2-(trifluoromethoxy)benzamide
Show/Hide
|
C24H25BrF3N5O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0871069
|
4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-2-trifluoromethoxy-benzenesulfonamide hydrochloride
Show/Hide
|
C25H30BrClF3N5O3S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0474124
|
N-[[1-[[1-(5-tert-butylpyridin-2-yl)pyrrol-3-yl]methyl]azetidin-3-yl]methyl]-2-(3-methylphenoxy)acetamide
Show/Hide
|
C27H34N4O2
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
|
CP0392540
|
N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-2-fluorobenzamide
Show/Hide
|
C23H26FN5O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0523198
|
4-(3,4-dimethylphenoxy)-3-((1R,2R)-2-phenylcyclopropanecarboxamido)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
|
C31H35N3O3
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0407601
|
1-(2-(pyrrolidine-1-carbonyl)morpholino)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
|
C28H35F3N4O3
|
1
|
| 1 |
IC50 = 173 nM
|
|
|
|
CP0536166
|
(1S,3S)-N1-((1,3-dimethyl-1H-pyrazol-4-yl)methyl)-N3-(7-methoxy-4-methylquinolin-2-yl)cyclohexane-1,3-diamine
Show/Hide
|
C23H31N5O
|
1
|
| 1 |
IC50 = 178 nM
|
|
|
|
CP0404744
|
5-chloro-6-oxo-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1,6-dihydropyridine-3-carboxamide
Show/Hide
|
C23H22ClF3N4O2
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0497117
|
N-[[4-[[5-methyl-4-(methylamino)pyrimidin-2-yl]amino]cyclohexyl]methyl]-3,5-bis(trifluoromethyl)benzamide
Show/Hide
|
C22H25F6N5O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0461181
|
N-[[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]cyclohexyl]methyl]-3,4-difluorobenzamide
Show/Hide
|
C21H27F2N5O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0562558
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-2-naphthamide
Show/Hide
|
C25H26F3N5O2
|
1
|
| 1 |
IC50 = 212 nM
|
|
|
|
CP0415740
|
N-[4-[[4-(dimethylamino)-6-methylpyrimidin-2-yl]amino]cyclohexyl]-4-(trifluoromethoxy)benzamide
Show/Hide
|
C21H26F3N5O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0492796
|
(1S,3S)-N1-(6-isopropoxy-4-methoxyquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C24H31N3O2S
|
1
|
| 1 |
IC50 = 231 nM
|
|
|
|
CP0452879
|
3-(1,4-oxazepan-4-yl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)azetidine-1-carboxamide
Show/Hide
|
C26H34F3N5O2
|
1
|
| 1 |
IC50 = 236 nM
|
|
|
|
CP0115100
|
2-(4-chlorophenyl)-5-[6-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyridin-3-yl]-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C21H21ClN6O
|
1
|
| 1 |
IC50 = 241 nM
|
|
|
|
CP0442722
|
(R)-5-guanidino-2-(2-(naphthalen-1-yl)acetamido)-N-(4-(trifluoromethyl)benzyl)pentanamide
Show/Hide
|
C26H28F3N5O2
|
1
|
| 1 |
IC50 = 243 nM
|
|
|
|
CP0440289
|
2-N-[1-[4-bromo-2-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-yl]-4-N,4-N-dimethylquinazoline-2,4-diamine
Show/Hide
|
C22H23BrF3N5O3S
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0554542
|
2-(3,4-difluorophenoxy)-N-((4-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)morpholin-2-yl)methyl)acetamide
Show/Hide
|
C25H24F5N3O3
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0528369
|
2-(3-chlorophenoxy)-N-[1-[(3-pyrrol-1-ylphenyl)methyl]piperidin-4-yl]acetamide
Show/Hide
|
C24H26ClN3O2
|
1
|
| 1 |
IC50 = 297 nM
|
|
|
|
CP0159041
|
6-(4-chlorophenyl)-3-[4-(2-cyclopropyl-2-hydroxyethoxy)-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C24H22ClN3O4
|
2
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
Ki = 3.5 nM
|
|
|
|
CP0554543
|
2-(3-chlorophenoxy)-N-((1-((1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-3-yl)methyl)piperidin-3-yl)methyl)acetamide
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 303 nM
|
|
|
|
CP0208350
|
1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C24H29F3N6O
|
1
|
| 1 |
IC50 = 308 nM
|
|
|
|
CP0503190
|
(R)-4-fluoro-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-1-naphthamide
Show/Hide
|
C25H25F4N5O2
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0551281
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)benzofuran-2-carboxamide
Show/Hide
|
C23H24F3N5O3
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0454255
|
N-[(1-methylpyrrol-2-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C25H29F3N4O
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0493262
|
2-(3-chlorophenoxy)-N-((1-((1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)methyl)acetamide
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0424935
|
2-N-[1-[[4-bromo-2-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]-4-N,4-N-dimethylquinazoline-2,4-diamine
Show/Hide
|
C23H25BrF3N5O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0496908
|
4-(3,4-dimethylphenoxy)-3-(3-phenylpropanamido)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
|
C30H35N3O3
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0454254
|
N-(2-pyridin-2-ylethyl)-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C25H27F3N4O
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0464319
|
1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(4-phenoxyphenyl)urea
Show/Hide
|
C34H36N4O4
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0474127
|
2-(3-chlorophenoxy)-N-(1-((2-(4-chlorophenyl)thiazol-4-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C23H23Cl2N3O2S
|
1
|
| 1 |
IC50 = 347 nM
|
|
|
|
CP0565539
|
(1R,2S,4S,6S)-N2-(6-methoxy-4-methylquinolin-2-yl)-N6-(thiophen-3-ylmethyl)bicyclo[2.2.1]heptane-2,6-diamine
Show/Hide
|
C23H27N3OS
|
1
|
| 1 |
IC50 = 369 nM
|
|
|
|
CP0464318
|
4-(naphthalen-2-yloxy)-3-(3-phenylpropanamido)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
|
C32H33N3O3
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0452773
|
(1R,3R)-N1-(6-methoxy-4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
IC50 = 411 nM
|
|
|
|
CP0127555
|
3-phenyl-3-(3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ureido)propanoic acid
Show/Hide
|
C27H29F3N4O3
|
1
|
| 1 |
IC50 = 412 nM
|
|
|
|
CP0534432
|
1-(4-(pyrrolidine-1-carbonyl)piperazin-1-yl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
|
C28H36F3N5O2
|
1
|
| 1 |
IC50 = 417 nM
|
|
|
|
CP0562556
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-6-methoxy-2-naphthamide
Show/Hide
|
C26H28F3N5O3
|
1
|
| 1 |
IC50 = 443 nM
|
|
|
|
CP0506349
|
N-[(2,4-dichlorophenyl)methyl]-1-[[1-[5-(trifluoromethyl)pyridin-2-yl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C24H23Cl2F3N4O
|
1
|
| 1 |
IC50 = 444 nM
|
|
|
|
CP0503191
|
(R)-2-(2-(1H-indol-2-yl)acetamido)-5-guanidino-N-(4-(trifluoromethyl)benzyl)pentanamide
Show/Hide
|
C24H27F3N6O2
|
1
|
| 1 |
IC50 = 512 nM
|
|
|
|
CP0376184
|
3-cinnamamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0461710
|
(1S,3S)-N1-(6-chloroquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C20H22ClN3S
|
1
|
| 1 |
IC50 = 571 nM
|
|
|
|
CP0456056
|
2-(1-((5-(4-chlorophenyl)furan-2-yl)methyl)piperidin-4-yl)-1-(3-(hydroxymethyl)piperidin-1-yl)ethanone
Show/Hide
|
C24H31ClN2O3
|
1
|
| 1 |
IC50 = 597 nM
|
|
|
|
CP0485535
|
N-[[4-[(4-amino-5-methylpyrimidin-2-yl)amino]cyclohexyl]methyl]-3,5-bis(trifluoromethyl)benzamide
Show/Hide
|
C21H23F6N5O
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0422023
|
4-fluoro-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-ylcarbamoyl)benzenesulfonamide
Show/Hide
|
C24H24F4N4O3S
|
1
|
| 1 |
IC50 = 617 nM
|
|
|
|
CP0499941
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-7-methoxybenzofuran-2-carboxamide
Show/Hide
|
C24H26F3N5O4
|
1
|
| 1 |
IC50 = 622 nM
|
|
|
|
CP0474125
|
N-[2-(3-chlorophenoxy)ethyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-amine
Show/Hide
|
C25H27ClF3N3O
|
1
|
| 1 |
IC50 = 636 nM
|
|
|
|
CP0503312
|
2-(3-chlorophenoxy)-N-(1-((1-phenyl-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C24H26ClN3O2
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0454385
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-9,10-dihydroanthracene-9-carboxamide
Show/Hide
|
C29H30F3N5O2
|
1
|
| 1 |
IC50 = 763 nM
|
|
|
|
CP0404813
|
4-Bromo-N-{4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexyl}-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C24H27BrF3N5O3S
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0407599
|
2-(1-((5-(4-chlorophenyl)furan-2-yl)methyl)piperidin-4-yl)-N-(3,3,3-trifluoro-2-hydroxypropyl)acetamide
Show/Hide
|
C21H24ClF3N2O3
|
1
|
| 1 |
IC50 = 815 nM
|
|
|
|
CP0464533
|
6-N,6-N-dimethyl-2-N-[(1S,3S)-3-(thiophen-3-ylmethylamino)cyclohexyl]quinoline-2,6-diamine
Show/Hide
|
C22H28N4S
|
1
|
| 1 |
IC50 = 847 nM
|
|
|
|
CP0423811
|
2-(3-chlorophenoxy)-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C22H25ClN2O4
|
1
|
| 1 |
IC50 = 903 nM
|
|
|
|
CP0560213
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)quinoline-2-carboxamide
Show/Hide
|
C24H25F3N6O2
|
1
|
| 1 |
IC50 = 904 nM
|
|
|
|
CP0474086
|
2-(3-chlorophenoxy)-N-(1-((5-(5-(trifluoromethyl)pyridin-2-yl)furan-2-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C24H23ClF3N3O3
|
1
|
| 1 |
IC50 = 927 nM
|
|
|
|
CP0499942
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)benzo[b]thiophene-3-carboxamide
Show/Hide
|
C23H24F3N5O2S
|
1
|
| 1 |
IC50 = 952 nM
|
|
|
|
CP0464467
|
2-N-[[4-[[[4-bromo-2-(trifluoromethoxy)phenyl]methylamino]methyl]cyclohexyl]methyl]-4-N,4-N-dimethylquinazoline-2,4-diamine
Show/Hide
|
C26H31BrF3N5O
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0532118
|
(R)-2-(2-(benzo[b]thiophen-3-yl)acetamido)-5-guanidino-N-(4-(trifluoromethyl)benzyl)pentanamide
Show/Hide
|
C24H26F3N5O2S
|
1
|
| 1 |
IC50 = 1008 nM
|
|
|
|
CP0562557
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)quinoline-4-carboxamide
Show/Hide
|
C24H25F3N6O2
|
1
|
| 1 |
IC50 = 1034 nM
|
|
|
|
CP0567162
|
2-(4-chlorophenyl)-5-[4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl]-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C22H22ClN3O4
|
1
|
| 1 |
IC50 = 1173 nM
|
|
|
|
CP0379234
|
(4-Bromo-2-trifluoromethoxy-phenyl)-[4-(4-dimethylamino-quinazolin-2-ylamino)-piperidin-1-yl]-methanone
Show/Hide
|
C23H23BrF3N5O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0500842
|
2-(3-chlorophenoxy)-1-(4-(1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-3-ylamino)piperidin-1-yl)ethanone
Show/Hide
|
C23H22ClF3N4O2
|
1
|
| 1 |
IC50 = 1250 nM
|
|
|
|
CP0467182
|
(1S,3S)-N1-(6-methoxy-3-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
IC50 = 1390 nM
|
|
|
|
CP0500756
|
4-bromo-N-[[4-[[[4-(dimethylamino)quinazolin-2-yl]amino]methyl]cyclohexyl]methyl]-2-(trifluoromethoxy)benzamide
Show/Hide
|
C26H29BrF3N5O2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0431015
|
4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexylmethyl]-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C24H27BrF3N5O3S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0554544
|
2-(3-chlorophenoxy)-N-(1-((1-(isoxazol-3-yl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C21H23ClN4O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0442651
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)-1-naphthamide
Show/Hide
|
C25H26F3N5O2
|
1
|
| 1 |
IC50 = 1797 nM
|
|
|
|
CP0526889
|
(R)-N-(5-guanidino-1-oxo-1-(4-(trifluoromethyl)benzylamino)pentan-2-yl)isoquinoline-3-carboxamide
Show/Hide
|
C24H25F3N6O2
|
1
|
| 1 |
IC50 = 1814 nM
|
|
|
|
CP0431012
|
N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]-4-bromo-2-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C23H25BrF3N5O3S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0490324
|
1-(6-methoxy-4-methylquinolin-2-yl)-N-(thiophen-3-ylmethyl)piperidin-4-amine
Show/Hide
|
C21H25N3OS
|
1
|
| 1 |
IC50 = 2130 nM
|
|
|
|
CP0490515
|
2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-imidazol-4-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C24H24ClF3N4O2
|
1
|
| 1 |
IC50 = 2140 nM
|
|
|
|
CP0495240
|
4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide
Show/Hide
|
C23H25BrF3N5O3S
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0503310
|
2-(3,4-difluorophenoxy)-N-((1S,3S)-3-(1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-ylamino)cyclopentyl)acetamide
Show/Hide
|
C24H22F5N3O2
|
1
|
| 1 |
IC50 = 2260 nM
|
|
|
|
CP0464534
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(1S,3S)-N1-(6-methoxy-4-methylquinolin-2-yl)-N1-methyl-N3-(thiophen-3-ylmethyl)cyclopentane-1,3-diamine
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C22H27N3OS
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1
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| 1 |
IC50 = 2300 nM
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CP0474089
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2-(3-chlorophenoxy)-N-[1-(1H-indol-5-ylmethyl)piperidin-4-yl]acetamide
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C22H24ClN3O2
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1
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| 1 |
IC50 = 2340 nM
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CP0464532
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N-methyl-N-[2-[[(1S,3S)-3-(thiophen-3-ylmethylamino)cyclohexyl]amino]quinolin-6-yl]acetamide
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C23H28N4OS
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1
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| 1 |
IC50 = 2520 nM
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CP0425370
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4-Bromo-N-[4-(quinazolin-2-ylaminomethyl)-cyclohexyl]-2-trifluoromethoxy-benzenesulfonamide
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C22H22BrF3N4O3S
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1
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| 1 |
IC50 = 2700 nM
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CP0466919
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Butane-1-sulfonic acid {4-[(4-dimethylamino-quinazolin-2-ylamino)-methyl]-cyclohexylmethyl}-amide
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C22H35N5O2S
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1
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| 1 |
IC50 = 2900 nM
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CP0565537
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6-methoxy-4-methyl-N-((1-(thiophen-3-ylmethyl)piperidin-3-yl)methyl)quinolin-2-amine
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C22H27N3OS
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1
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| 1 |
IC50 = 2990 nM
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CP0503311
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2-(3-chlorophenoxy)-N-(1-((1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrol-3-yl)methyl)piperidin-3-yl)acetamide
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C24H24ClF3N4O2
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1
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| 1 |
IC50 = 3050 nM
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CP0413782
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2-(4-chlorophenyl)-5-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-4H-pyrrolo[3,4-c]pyrazol-6-one
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C24H25ClN4O3
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1
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| 1 |
IC50 = 3057 nM
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CP0039984
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CGP 71683
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C26H29N5O2S
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1
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| 1 |
IC50 = 3500 nM
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CP0565541
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6-methoxy-4-methyl-N-(2-(thiophen-3-ylmethylamino)ethyl)quinolin-2-amine
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C18H21N3OS
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1
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| 1 |
IC50 = 3590 nM
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CP0464535
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(1S,3S)-N1-(thiophen-3-ylmethyl)-N3-(4-(trifluoromethyl)quinolin-2-yl)cyclohexane-1,3-diamine
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C21H22F3N3S
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1
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| 1 |
IC50 = 4800 nM
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CP0251713
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6-(4-chlorophenyl)-3-[4-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
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C23H21ClN4O4
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2
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| 1 |
IC50 = 5000 nM
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| 2 |
Ki = 3.1 nM
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CP0530318
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(1S,2R,4R,6R)-N2-(6-methoxy-4-methylquinolin-2-yl)-N6-(thiophen-3-ylmethyl)bicyclo[2.2.1]heptane-2,6-diamine
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C23H27N3OS
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1
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| 1 |
IC50 = 5010 nM
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CP0457564
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(1S,3S)-N1-(8-chloroquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine
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C20H22ClN3S
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1
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| 1 |
IC50 = 5100 nM
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CP0392533
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2-N-[[4-[[[4-bromo-2-(trifluoromethoxy)phenyl]methyl-methylamino]methyl]cyclohexyl]methyl]-4-N,4-N-dimethylquinazoline-2,4-diamine
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C27H33BrF3N5O
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1
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| 1 |
IC50 = 5600 nM
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CP0494619
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4-bromo-N-[[4-[[[4-(dimethylamino)quinazolin-2-yl]amino]methyl]cyclohexyl]methyl]-N-methyl-2-(trifluoromethoxy)benzenesulfonamide
Show/Hide
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C26H31BrF3N5O3S
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1
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| 1 |
IC50 = 5800 nM
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CP0503845
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2-N-[[1-[4-bromo-2-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-yl]methyl]-4-N,4-N-dimethylquinazoline-2,4-diamine
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C23H25BrF3N5O3S
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1
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| 1 |
IC50 = 6000 nM
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CP0404812
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N-[[4-[[[4-(dimethylamino)quinazolin-2-yl]amino]methyl]cyclohexyl]methyl]octane-1-sulfonamide
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C26H43N5O2S
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1
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| 1 |
IC50 = 6700 nM
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CP0528368
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2-(3-chlorophenoxy)-N-(1-((2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
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C26H30ClN3O2
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1
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| 1 |
IC50 = 9650 nM
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CP0453926
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2-((1S,3S)-3-(thiophen-3-ylmethylamino)cyclohexylamino)quinoline-4-carbonitrile
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C21H22N4S
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1
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| 1 |
IC50 = 9920 nM
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CP0431013
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N-[[4-[[[4-(dimethylamino)quinazolin-2-yl]amino]methyl]cyclohexyl]methyl]propane-2-sulfonamide
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C21H33N5O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0493156
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N-[[4-[[[4-(dimethylamino)quinazolin-2-yl]amino]methyl]cyclohexyl]methyl]methanesulfonamide
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C19H29N5O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0522853
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6-methoxy-4-methyl-N-(4-(thiophen-3-ylmethylamino)butyl)quinolin-2-amine
Show/Hide
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C20H25N3OS
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1
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| 1 |
IC50 > 33000 nM
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CP0493264
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2-(3-chlorophenoxy)-N-(1-((1-cyclopentyl-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
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C23H30ClN3O2
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1
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| 1 |
IC50 > 33000 nM
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CP0374895
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3-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-1-methyl-1-phenylurea
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C29H34N4O3
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1
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| 1 |
IC50 > 1000 nM
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CP0376186
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4-(3,4-dimethylphenylthio)-3-(3-phenylpropanamido)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
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C30H35N3O2S
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1
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| 1 |
IC50 > 1000 nM
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CP0376188
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phenyl N-[2-(3,4-dimethylphenoxy)-5-(2-pyrrolidin-1-ylethylcarbamoyl)phenyl]carbamate
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C28H31N3O4
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1
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| 1 |
IC50 > 1000 nM
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CP0394653
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3-acetamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
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C23H29N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0422199
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1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-(pyridin-2-yl)urea
Show/Hide
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C27H31N5O3
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1
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| 1 |
IC50 > 1000 nM
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CP0456437
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4-(3,4-dimethylphenoxy)-3-propionamido-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
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C24H31N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0503371
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4-(3,4-dimethylphenoxy)-3-(2-phenylacetamido)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
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C29H33N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0515788
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N-(2-aminoethyl)-4-(3,4-dimethylphenoxy)-3-(3-phenylpropanoylamino)benzamide
Show/Hide
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C26H29N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0554702
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4-(3,4-dimethylphenylamino)-3-(3-phenylpropanamido)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Show/Hide
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C30H36N4O2
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1
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| 1 |
IC50 > 1000 nM
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CP0051323
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(S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]-propylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester
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C31H37F2N5O6
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1
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| 1 |
Kd = 0.5754 nM
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CP0251717
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6-(4-chlorophenyl)-3-[6-[3-(methylamino)pyrrolidin-1-yl]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C22H21ClN6O
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1
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| 1 |
Ki = 0.4 nM
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CP0306173
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6-(4-chlorophenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C25H25ClN4O3
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1
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| 1 |
Ki = 0.5 nM
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CP0534409
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6-(4-chlorophenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]pyrazolo[5,1-f][1,2,4]triazin-4-one
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C24H24ClN5O3
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1
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| 1 |
Ki = 0.7 nM
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CP0251719
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6-(4-chlorophenyl)-3-[6-[3-(3-hydroxyazetidin-1-yl)pyrrolidin-1-yl]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
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C24H23ClN6O2
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1
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| 1 |
Ki = 0.8 nM
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CP0486039
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(S)-3-{[5-(2-Chloro-4-methyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
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C24H31ClN4O2S
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1
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| 1 |
Ki = 1 nM
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CP0490106
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(S)-3-{[5-(4-Ethyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C25H34N4O2S
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1
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| 1 |
Ki = 1 nM
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CP0408719
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(S)-3-[(4'-Chloro-biphenyl-4-carbonyl)-methyl-amino]-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
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C25H31ClN4O2
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1
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| 1 |
Ki = 2 nM
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CP0480646
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(S)-3-{[5-(2-Chloro-4-ethoxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C25H33ClN4O3S
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1
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| 1 |
Ki = 2 nM
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CP0509775
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(S)-3-{Methyl-[5-(4-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H29F3N4O2S
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1
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| 1 |
Ki = 2 nM
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CP0509776
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(S)-3-{[5-(4-Chloro-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C23H29ClN4O2S
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1
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| 1 |
Ki = 2 nM
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CP0356429
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6-(4-chlorophenyl)-3-[4-[(2S)-3-ethylsulfonyl-2-hydroxypropoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C24H24ClN3O6S
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1
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| 1 |
Ki = 2.4 nM
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CP0393423
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(S)-3-{[5-(2,4-Dimethyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C25H34N4O2S
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1
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| 1 |
Ki = 3 nM
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CP0393903
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(S)-3-{[5-(4-Chloro-2-methyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H31ClN4O2S
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1
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| 1 |
Ki = 3 nM
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CP0445595
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(S)-3-{[5-(4-Methoxy-2-methyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C25H34N4O3S
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1
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| 1 |
Ki = 3 nM
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CP0497413
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(S)-3-{[5-(2,4-Dichloro-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C23H28Cl2N4O2S
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1
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| 1 |
Ki = 3 nM
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CP0499072
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(S)-3-[Methyl-(5-p-tolyl-thiophene-2-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H32N4O2S
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1
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| 1 |
Ki = 3 nM
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CP0045223
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(S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one
Show/Hide
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C27H36ClN3O
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1
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| 1 |
Ki = 3.3 nM
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CP0055310
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6-(4-chlorophenyl)-3-[4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C24H20ClF2N3O4
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1
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| 1 |
Ki = 3.4 nM
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CP0860611
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3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid [1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-amide
Show/Hide
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C32H42F3N5O2
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1
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| 1 |
Ki = 3.9 nM
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CP0375699
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(S)-3-{[5-(4-Methoxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H32N4O3S
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1
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| 1 |
Ki = 4 nM
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CP0490689
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(S)-3-{Methyl-[5-(4-trifluoromethoxy-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H29F3N4O3S
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1
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| 1 |
Ki = 4 nM
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CP0055231
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6-(4-chlorophenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]imidazo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C24H24ClN5O3
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1
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| 1 |
Ki = 4.4 nM
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CP0534426
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6-(4-chlorophenyl)-3-[4-[(3R)-3-hydroxypyrrolidin-1-yl]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C23H21ClN4O3
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1
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| 1 |
Ki = 4.8 nM
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CP0391976
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(S)-3-[(4'-Methoxy-biphenyl-4-carbonyl)-methyl-amino]-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C26H34N4O3
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1
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| 1 |
Ki = 5 nM
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CP0527946
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(S)-3-{[5-(4-Isopropyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C26H36N4O2S
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1
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| 1 |
Ki = 5 nM
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CP0430213
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3-{[4-(4-Fluoro-phenoxy)-benzoyl]-methyl-amino}-pyrrolidine-1-carboxylic acid {1-[3-(4-chloro-phenyl)-propyl]-pyrrolidin-3-yl}-methyl-amide
Show/Hide
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C33H38ClFN4O3
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1
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| 1 |
Ki = 5.3 nM
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CP0072237
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6-(4-chlorophenyl)-3-[6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C21H18ClN5O2
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1
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| 1 |
Ki = 5.3 nM
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CP0434137
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4'-(2,4-dioxo-1-phenyl-3-m-tolyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-biphenyl-3-carbonitrile
Show/Hide
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C34H30N4O2
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1
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| 1 |
Ki = 6 nM
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CP0434138
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4'-[3-(3-methoxy-phenyl)-2,4-dioxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
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C34H30N4O3
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1
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| 1 |
Ki = 6 nM
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CP0112764
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6-(5-chloropyridin-2-yl)-3-[4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C23H19ClF2N4O4
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1
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| 1 |
Ki = 6.5 nM
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CP0306172
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6-(5-chloropyridin-2-yl)-3-[4-[(2R)-2-cyclopropyl-2-hydroxyethoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C23H21ClN4O4
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1
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| 1 |
Ki = 6.5 nM
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CP0464659
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(S)-3-{[5-(4-Dimethylamino-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C25H35N5O2S
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1
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| 1 |
Ki = 7 nM
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CP0433604
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3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid {1-[3-(4-chloro-phenyl)-propyl]-pyrrolidin-3-yl}-methyl-amide
Show/Hide
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C34H38ClF3N4O2
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1
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| 1 |
Ki = 7.3 nM
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CP0045214
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(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4'-fluoro-N-methylbiphenyl-4-carboxamide
Show/Hide
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C27H29FN2O
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1
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| 1 |
Ki = 7.4 nM
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CP0185293
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1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(4-methoxy-pyridin-3-yl)-benzyl]-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C34H33FN4O4
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1
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| 1 |
Ki = 8 nM
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CP0463161
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5-chloro-4'-(2,4-dioxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-biphenyl-3-carbonitrile
Show/Hide
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C27H23ClN4O2
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1
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| 1 |
Ki = 8 nM
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CP0368276
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6-(5-chloropyrimidin-2-yl)-3-[4-[(3,3-difluoro-1-hydroxycyclobutyl)methoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C22H18ClF2N5O4
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1
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| 1 |
Ki = 9 nM
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CP0108824
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6-(5-chloropyridin-2-yl)-3-[4-[(3R)-3-hydroxypyrrolidin-1-yl]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
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C22H20ClN5O3
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1
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| 1 |
Ki = 9.1 nM
|
|
|
|
CP0439022
|
(S)-3-{[5-(2-Chloro-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C23H29ClN4O2S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0157291
|
5-{4-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-phenyl}-nicotinonitrile
Show/Hide
|
C34H30FN5O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0062285
|
1-(4-(piperidin-1-ylmethyl)phenethyl)-4-phenethylpiperazin-2-one
Show/Hide
|
C26H35N3O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0045215
|
(S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methylpicolinamide
Show/Hide
|
C26H28ClN3O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0283011
|
(S)-6-(4-chlorophenyl)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methylnicotinamide
Show/Hide
|
C26H28ClN3O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0463162
|
4'-[1-cyclohexyl-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C34H36N4O3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0188530
|
6-(4-chlorophenyl)-3-[6-(4-hydroxypiperidin-1-yl)pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H20ClN5O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0039176
|
1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(5-methoxy-pyridin-3-yl)-benzyl]-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C34H33FN4O4
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0147638
|
6-(4-chlorophenyl)-3-[4-(2-cyclopropyl-2-hydroxyethoxy)-3-methoxyphenyl]pyrazolo[5,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H21ClN4O4
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0251715
|
6-(5-chloropyrimidin-2-yl)-3-[4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C21H20ClN5O4
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0370371
|
6-(5-chloropyridin-2-yl)-3-[4-(2-cyclopropyl-2-hydroxyethoxy)-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H21ClN4O4
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0483527
|
(S)-3-{Methyl-[5-(4-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((S)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C24H29F3N4O2S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0525871
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid {1-[2-(4-chloro-benzenesulfonyl)-ethyl]-pyrrolidin-3-yl}-methyl-amide
Show/Hide
|
C33H36ClF3N4O4S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0370430
|
7-(4-fluorophenethyl)-2-(4-(piperidin-1-ylmethyl)phenethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
Show/Hide
|
C29H34FN3O
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0185185
|
6-(4-chlorophenyl)-3-[6-(3-hydroxyazetidin-1-yl)pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H16ClN5O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0370372
|
6-(5-chloropyridin-2-yl)-3-[4-[(2S)-3-ethylsulfonyl-2-hydroxypropoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H23ClN4O6S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0551238
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-N-methyl-4-phenylbenzamide
Show/Hide
|
C29H36N2O3
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0441754
|
5-anilino-2-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]isoindole-1,3-dione
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0375732
|
(S)-3-[(4'-Methoxy-2'-methyl-biphenyl-4-carbonyl)-methyl-amino]-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C27H36N4O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0439707
|
4'-[1-cyclohexylmethyl-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C35H38N4O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0356431
|
6-(5-chloropyrimidin-2-yl)-3-[4-(2-cyclopropyl-2-hydroxyethoxy)-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H20ClN5O4
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0276533
|
(S)-4-(5-chloropyridin-2-yl)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methylbenzamide
Show/Hide
|
C26H28ClN3O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0540214
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid {1-[2-(4-chloro-phenoxy)-ethyl]-pyrrolidin-3-yl}-methyl-amide
Show/Hide
|
C33H36ClF3N4O3
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0378151
|
(S)-3-[Methyl-(5-o-tolyl-thiophene-2-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C24H32N4O2S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0451684
|
3-({4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-yl}-methyl-amino)-propionitrile
Show/Hide
|
C38H38FN5O3
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0464726
|
N-[4-[2-(diethylamino)ethoxy]-3-methoxyphenyl]-N-methyl-4-[4-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C28H31F3N2O3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0536144
|
N-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-N-methyl-4-phenylbenzamide
Show/Hide
|
C27H30N2O3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0536145
|
N-[4-[2-(diethylamino)ethoxy]-3-methoxyphenyl]-N-methyl-4-phenylbenzamide
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0374867
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-6-phenylthieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C25H25N3O3S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0442858
|
2-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-5-phenoxyisoindole-1,3-dione
Show/Hide
|
C27H26N2O5
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0511214
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-7-phenylquinazolin-4-one
Show/Hide
|
C27H27N3O3
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0283009
|
(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-5-(4-fluorophenyl)-N-methylpicolinamide
Show/Hide
|
C26H28FN3O
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0525870
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid [1-(3-cyclopentyl-propyl)-pyrrolidin-3-yl]-methyl-amide
Show/Hide
|
C33H43F3N4O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0213085
|
4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C35H31FN4O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0374402
|
8-[4-(6-amino-pyridin-3-yl)-benzyl]-1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C33H32FN5O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0200183
|
6-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H16ClN3O3
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0194281
|
N-(3-fluorophenyl)-4-oxo-5-[2-[4-(piperidin-1-ylmethyl)phenyl]ethyl]-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxamide
Show/Hide
|
C27H30FN5O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0525875
|
3-(3-Biphenyl-4-yl-1-methyl-ureido)-pyrrolidine-1-carboxylic acid {1-[3-(4-chloro-phenyl)-propyl]-pyrrolidin-3-yl}-methyl-amide
Show/Hide
|
C33H40ClN5O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0428199
|
4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(S)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide
Show/Hide
|
C35H40ClF3N4O2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0194285
|
7-(4-fluorophenyl)-2-(4-(piperidin-1-ylmethyl)phenethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
Show/Hide
|
C27H30FN3O
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0045217
|
(S)-N-(6-(((2-(dimethylamino)-2-oxoethyl)(methyl)amino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4'-fluoro-N-methylbiphenyl-4-carboxamide
Show/Hide
|
C30H34FN3O2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0439709
|
1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-naphthalen-1-yl-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C34H30FN5O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0421192
|
4-cyclohexyl-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]benzamide
Show/Hide
|
C28H40N2O3
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0551237
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0464500
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-7-phenyl-1,2,3-benzotriazin-4-one
Show/Hide
|
C26H26N4O3
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0368261
|
6-(4-chlorophenyl)-3-[4-(2-cyclopropyl-2-hydroxyethoxy)-3-methoxyphenyl]imidazo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C23H21ClN4O4
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0085538
|
6-(5-chloropyrimidin-2-yl)-3-[4-[(2S)-3-ethylsulfonyl-2-hydroxypropoxy]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H22ClN5O6S
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0540215
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid [1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-amide
Show/Hide
|
C33H43F3N4O2
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0110350
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0444781
|
N-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-4-phenylbenzamide
Show/Hide
|
C26H28N2O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0485276
|
N-[3-acetyl-4-[2-(diethylamino)ethoxy]phenyl]-4-phenylbenzamide
Show/Hide
|
C27H30N2O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0536143
|
N-[4-[2-(diethylamino)ethoxy]-3-methoxyphenyl]-4-phenylbenzamide
Show/Hide
|
C26H30N2O3
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0461948
|
2-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-5-phenylsulfanylisoindole-1,3-dione
Show/Hide
|
C27H26N2O4S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0445995
|
(S)-4-(2-cyclohexylethyl)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one
Show/Hide
|
C27H43N3O
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0493080
|
(S)-3-{[5-(4-Fluoro-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C23H29FN4O2S
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0408512
|
N-[3-methoxy-4-(2-piperidin-1-ylethoxy)phenyl]-4-phenylbenzamide
Show/Hide
|
C27H30N2O3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0547184
|
4-Benzyl-N-[4-(2-diisopropylamino-ethoxy)-3-methoxy-phenyl]-benzamide
Show/Hide
|
C29H36N2O3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0551232
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-4-(2-methylphenyl)benzamide
Show/Hide
|
C29H36N2O3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0441752
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-6-phenoxy-1,2,3-benzotriazin-4-one
Show/Hide
|
C26H26N4O4
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0496771
|
4-cyclohexyl-N-[3-methoxy-4-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]phenyl]benzamide
Show/Hide
|
C26H34N2O3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0157290
|
1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyridin-4-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C33H31FN4O3
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0344438
|
4'-(2,4-dioxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl)-biphenyl-3-carbonitrile
Show/Hide
|
C27H24N4O2
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0161877
|
1-((S)-6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(2-(tetrahydrothiophen-2-yl)ethyl)piperazin-2-one
Show/Hide
|
C25H39N3OS
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0551753
|
3-{[5-(4-Chloro-phenyl)-5-oxo-pentanoyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-[1-(3-phenyl-propyl)-pyrrolidin-3-yl]-amide
Show/Hide
|
C31H41ClN4O3
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0333634
|
1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C31H30FN5O3
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0421212
|
N-[4-[2-[benzyl(methyl)amino]ethoxy]-3-methoxyphenyl]-4-phenylbenzamide
Show/Hide
|
C30H30N2O3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0526924
|
N-[4-[2-(diethylamino)ethoxy]-3-ethylphenyl]-4-phenylbenzamide
Show/Hide
|
C27H32N2O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0530734
|
N-[4-[2-(dimethylamino)ethoxy]-3-methoxyphenyl]-4-phenylbenzamide
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0442890
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-7-phenoxyquinazolin-4-one
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0524394
|
N-[4-(1-azabicyclo[3.2.1]octan-5-yloxy)-3-methoxyphenyl]-4-cyclohexylbenzamide
Show/Hide
|
C27H34N2O3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0422710
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-(1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C26H31F3N4O2
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0497767
|
(S)-3-{Methyl-[5-(2-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C24H29F3N4O2S
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0508736
|
(S)-3-{[5-(4-Ethoxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C25H34N4O3S
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0408511
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]phenyl]-4-phenylbenzamide
Show/Hide
|
C27H32N2O2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0559606
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O2
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0453695
|
4-cyclohexyl-N-[3-methoxy-4-(1-methylpyrrolidin-3-yl)oxyphenyl]benzamide
Show/Hide
|
C25H32N2O3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0514176
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid (1-butyl-pyrrolidin-3-yl)-methyl-amide
Show/Hide
|
C29H37F3N4O2
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0548890
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-pyrrolidin-3-yl-amide
Show/Hide
|
C25H29F3N4O2
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0525874
|
3-{[2-(4-tert-Butyl-phenoxy)-acetyl]-methyl-amino}-pyrrolidine-1-carboxylic acid {1-[3-(4-chloro-phenyl)-propyl]-pyrrolidin-3-yl}-methyl-amide
Show/Hide
|
C32H45ClN4O3
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0525873
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-[1-(tetrahydro-pyran-4-yl)-pyrrolidin-3-yl]-amide
Show/Hide
|
C30H37F3N4O3
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0159042
|
6-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)imidazo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C19H15ClN4O3
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0194282
|
5-(4-((diethylamino)methyl)phenethyl)-N-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
Show/Hide
|
C26H30FN5O2
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0394136
|
4-benzyl-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-N-methylbenzamide
Show/Hide
|
C30H38N2O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0467318
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-4-[4-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C29H33F3N2O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0485275
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-3-phenoxybenzamide
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0464580
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-7-phenoxy-1,2,3-benzotriazin-4-one
Show/Hide
|
C26H26N4O4
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0467117
|
4-cyclohexyl-N-[3-methoxy-4-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]phenyl]benzamide
Show/Hide
|
C26H34N2O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0524393
|
4-cyclohexyl-N-[4-(4-ethylpiperazin-1-yl)oxy-3-methoxyphenyl]benzamide
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0499943
|
5-(4-((dimethylamino)methyl)phenethyl)-N-(4-fluorophenyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
Show/Hide
|
C24H26FN5O2
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0430211
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-{1-[2-(pyrrolidine-1-sulfonyl)-ethyl]-pyrrolidin-3-yl}-amide
Show/Hide
|
C31H40F3N5O4S
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0540216
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-[1-(1-methyl-piperidin-4-yl)-pyrrolidin-3-yl]-amide
Show/Hide
|
C31H40F3N5O2
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0437448
|
4'-[1-cyclopropylmethyl-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C32H32N4O3
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0185186
|
6-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)pyrazolo[5,1-f][1,2,4]triazin-4-one
Show/Hide
|
C19H15ClN4O3
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0104441
|
1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyridin-3-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C33H31FN4O3
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0522669
|
8-(3'-acetyl-biphenyl-4-ylmethyl)-1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C36H34FN3O4
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0194289
|
(S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(3-(trifluoromethyl)phenethyl)piperazin-2-one
Show/Hide
|
C28H36F3N3O
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0430208
|
3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid [1-(2-hydroxy-ethyl)-pyrrolidin-3-yl]-methyl-amide
Show/Hide
|
C27H33F3N4O3
|
1
|
| 1 |
Ki = 96 nM
|
|
|
|
CP0463163
|
4'-[1-cyclopropyl-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C31H30N4O3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0559607
|
4-cyclohexyl-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-N-methylbenzamide
Show/Hide
|
C29H42N2O3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0082135
|
(S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4'-fluoro-N-methylbiphenyl-4-carboxamide
Show/Hide
|
C31H34FN3O2
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0449043
|
1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-phenyl-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C30H28FN5O2
|
1
|
| 1 |
Ki = 115 nM
|
|
|
|
CP0161873
|
(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-5-phenylpicolinamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
Ki = 118 nM
|
|
|
|
CP0448998
|
6-(5-chloropyridin-2-yl)-3-[6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C20H17ClN6O2
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0421191
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-2-methyl-4-phenylbenzamide
Show/Hide
|
C29H36N2O3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0503390
|
2-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-5-phenylisoindole-1,3-dione
Show/Hide
|
C29H32N2O4
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0194286
|
(S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxamido)-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)piperazine-1-carboxamide
Show/Hide
|
C30H33FN4O2
|
1
|
| 1 |
Ki = 129 nM
|
|
|
|
CP0276531
|
(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-2-yl)benzamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0547177
|
Biphenyl-4-carboxylic acid methyl-{3-[methyl-(1-methyl-pyrrolidin-3-yl)-carbamoyl]-propyl}-amide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0082125
|
(S)-4'-fluoro-N-methyl-N-(6-((3-oxopiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)biphenyl-4-carboxamide
Show/Hide
|
C29H30FN3O2
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0140703
|
(S)-1-(((S)-6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxamido)-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C32H36FN3O2
|
1
|
| 1 |
Ki = 146 nM
|
|
|
|
CP0353013
|
7-(4-fluorobenzoyl)-2-(4-(piperidin-1-ylmethyl)phenethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
Show/Hide
|
C28H30FN3O2
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0445596
|
(R)-3-{Methyl-[5-(4-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C24H29F3N4O2S
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0373712
|
3-benzyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C31H30FN5O2
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0434140
|
N-[3-[4-[[1-[(2-fluorophenyl)methyl]-3-(3-methoxyphenyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]phenyl]acetamide
Show/Hide
|
C36H35FN4O4
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0538531
|
3-benzyl-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]benzamide
Show/Hide
|
C29H36N2O3
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0562389
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-3-methyl-4-phenylbenzamide
Show/Hide
|
C29H36N2O3
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0403082
|
4'-[3-(3-methoxy-phenyl)-1-methyl-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C29H28N4O3
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0257092
|
(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-6-(4-fluorophenyl)-N-methylnicotinamide
Show/Hide
|
C26H28FN3O
|
1
|
| 1 |
Ki = 184 nM
|
|
|
|
CP0483528
|
(R)-3-{Methyl-[5-(4-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((S)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C24H29F3N4O2S
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0381846
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-4-phenoxybenzamide
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0503391
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]phenyl]-9-oxofluorene-2-carboxamide
Show/Hide
|
C28H30N2O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0522671
|
3-butyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C28H32FN5O2
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0373711
|
4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-4-carbonitrile
Show/Hide
|
C35H31FN4O3
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0082123
|
7-(4-fluorobenzyl)-2-(4-(piperidin-1-ylmethyl)phenethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
Show/Hide
|
C28H32FN3O
|
1
|
| 1 |
Ki = 228 nM
|
|
|
|
CP0437449
|
8-[4-(4-chloro-pyridin-3-yl)-benzyl]-1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C33H30ClFN4O3
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0421314
|
N-[4-[2-(diethylamino)ethoxy]-3-(1-hydroxyethyl)phenyl]-4-phenylbenzamide
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0516233
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-4-[3-(trifluoromethyl)phenyl]benzamide
Show/Hide
|
C29H33F3N2O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0551210
|
N-[4-[2-(diethylamino)ethoxy]-3-methoxyphenyl]-N-ethyl-4-phenylbenzamide
Show/Hide
|
C28H34N2O3
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0449040
|
4'-[3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-3-carbonitrile
Show/Hide
|
C28H26N4O3
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0394574
|
1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(2-methyl-imidazol-1-yl)-benzyl]-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C32H32FN5O3
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0082131
|
(S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-5-(4-fluorophenyl)-N-methylpicolinamide
Show/Hide
|
C30H33FN4O2
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0480645
|
(S)-3-{[5-(2,6-Dimethyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C25H34N4O2S
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0522670
|
1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(6-methoxy-pyridin-3-yl)-benzyl]-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C34H33FN4O4
|
1
|
| 1 |
Ki = 315 nM
|
|
|
|
CP0442859
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]phenyl]-N-methyl-9,10-dihydrophenanthrene-2-carboxamide
Show/Hide
|
C30H36N2O2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0467206
|
3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-6-phenoxyquinazolin-4-one
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0445592
|
(S)-3-{[5-(3-Chloro-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
|
C23H29ClN4O2S
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0437450
|
1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyrimidin-5-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C32H30FN5O3
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0953973
|
(R)-3-{Methyl-[5-(4-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid (R)-[1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-amide
Show/Hide
|
C31H41F3N4O2S
|
1
|
| 1 |
Ki = 338 nM
|
|
|
|
CP0434143
|
3-cyclohexyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C30H34FN5O2
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0449042
|
1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C34H34FN5O2
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0408510
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-fluorophenyl]-4-phenylbenzamide
Show/Hide
|
C27H31FN2O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0485277
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-N-methyl-3-phenoxybenzamide
Show/Hide
|
C29H36N2O4
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0393930
|
2-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-6-phenyl-3H-isoindol-1-one
Show/Hide
|
C29H34N2O3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0480364
|
N-[4-[2-[di(propan-2-yl)amino]ethoxy]phenyl]-N-methyl-9H-fluorene-2-carboxamide
Show/Hide
|
C29H34N2O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0394575
|
1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-3-phenethyl-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
|
C32H32FN5O2
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0499032
|
2-(4-Trifluoromethyl-phenyl)-thiazole-5-carboxylic acid (1-{[1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-carbamoyl}-pyrrolidin-3-yl)-methyl-amide
Show/Hide
|
C30H40F3N5O2S
|
1
|
| 1 |
Ki = 456 nM
|
|
|
|
CP0432697
|
5-(4-((diethylamino)methyl)phenethyl)-4-oxo-N-(3-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
Show/Hide
|
C27H30F3N5O2
|
1
|
| 1 |
Ki = 497 nM
|
|
|
|
CP0467209
|
N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0463164
|
1-(2-fluoro-benzyl)-8-(3'-methoxy-biphenyl-4-ylmethyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C35H34FN3O4
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1
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| 1 |
Ki = 620 nM
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CP0194284
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N-(4-fluorophenyl)-1-oxo-2-[2-[4-(piperidin-1-ylmethyl)phenyl]ethyl]-3,4-dihydropyrrolo[1,2-a]pyrazine-7-carboxamide
Show/Hide
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C28H31FN4O2
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1
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| 1 |
Ki = 625 nM
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CP0406532
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1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(6-methyl-pyridin-3-yl)-benzyl]-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C34H33FN4O3
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1
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| 1 |
Ki = 640 nM
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CP0254323
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(S)-N-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-2-yl)benzamide
Show/Hide
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C30H34N4O2
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1
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| 1 |
Ki = 727 nM
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CP0082124
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N-[(2S)-6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-1,2,3,4-tetrahydronaphthalen-2-yl]-4-(4-fluorophenyl)-N-methylbenzamide
Show/Hide
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C29H31FN2O3S
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1
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| 1 |
Ki = 755 nM
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CP0562396
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3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-6-phenylthieno[2,3-d]pyrimidin-4-one
Show/Hide
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C25H25N3O3S
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1
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| 1 |
Ki = 794.33 nM
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CP0045216
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(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-3-yl)benzamide
Show/Hide
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C26H29N3O
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1
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| 1 |
Ki = 890 nM
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CP0515362
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(S)-3-{[5-(3-Methoxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H32N4O3S
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1
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| 1 |
Ki = 900 nM
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CP0393931
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N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-9,10-dihydrophenanthrene-2-carboxamide
Show/Hide
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C27H28N2O2
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1
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| 1 |
Ki = 1000 nM
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CP0551287
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6-(4-chlorophenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]quinazolin-4-one
Show/Hide
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C27H26ClN3O3
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1
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| 1 |
Ki = 1000 nM
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CP0439424
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4-(5-methoxy-pyridin-3-yl)-N-methyl-N-{(S)-1-[(S)-3-(3-phenyl-propylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-benzamide
Show/Hide
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C32H39N5O3
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1
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| 1 |
Ki = 1000 nM
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CP0506578
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3-[1-Oxo-5-(4-trifluoromethyl-phenyl)-1,3-dihydro-isoindol-2-yl]-pyrrolidine-1-carboxylic acid methyl-[1-(3-phenyl-propyl)-pyrrolidin-3-yl]-amide
Show/Hide
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C34H37F3N4O2
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1
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| 1 |
Ki = 1019 nM
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CP0506577
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3-{[4-(6-Methoxy-pyridazin-3-yl)-benzoyl]-methyl-amino}-pyrrolidine-1-carboxylic acid [1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-amide
Show/Hide
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C31H44N6O3
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1
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| 1 |
Ki = 1043 nM
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CP0288190
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3-[1,1-di(acetyloxymethyl)propyl]-1-(3'-cyano-4-biphenylmethyl)-1-{2-[1-(4-methylbenzyl)-4-piperidinyl]ethyl}urea
Show/Hide
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C39H48N4O5
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1
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| 1 |
Ki = 1080 nM
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CP0394849
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2-(4-Trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acid (1-{[1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-carbamoyl}-pyrrolidin-3-yl)-methyl-amide
Show/Hide
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C30H41F3N6O2
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1
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| 1 |
Ki = 1096 nM
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CP0522672
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3-ethyl-1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C26H28FN5O2
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1
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| 1 |
Ki = 1100 nM
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CP0332300
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3-[1,1-di(acetyloxymethyl)propyl]-1-(2'-methoxy-4-biphenylmethyl)-1-{2-[1-(4-methylbenzyl)-4-piperidinyl]ethyl}urea
Show/Hide
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C39H51N3O6
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1
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| 1 |
Ki = 1200 nM
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CP0333635
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1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyrrol-1-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C32H31FN4O3
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1
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| 1 |
Ki = 1500 nM
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CP0480699
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(S)-3-{Methyl-[5-(3-trifluoromethyl-phenyl)-thiophene-2-carbonyl]-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H29F3N4O2S
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1
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| 1 |
Ki = 1800 nM
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CP0506528
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N-[4-[2-[di(propan-2-yl)amino]ethoxy]phenyl]dibenzofuran-2-carboxamide
Show/Hide
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C27H30N2O3
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1
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| 1 |
Ki = 1995.26 nM
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CP0486189
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1-(2-fluoro-benzyl)-8-(4-imidazol-1-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C24H24FN5O2
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1
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| 1 |
Ki = 2100 nM
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CP0451881
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(S)-3-{[5-(4-Cyano-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H29N5O2S
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1
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| 1 |
Ki = 2400 nM
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CP0045222
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(S)-N-(6-((dimethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-N-methyl-4-(pyridin-4-yl)benzamide
Show/Hide
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C26H29N3O
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1
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| 1 |
Ki = 2480 nM
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CP0454370
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5-(4-((diethylamino)methyl)phenethyl)-4-oxo-N-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
Show/Hide
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C27H30F3N5O2
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1
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| 1 |
Ki = 2482 nM
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CP0480365
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4-cyclohexyl-N-[4-[(1S,2S)-2-(dimethylamino)cyclohexyl]oxy-3-methoxyphenyl]benzamide
Show/Hide
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C28H38N2O3
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1
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| 1 |
Ki = 2511.89 nM
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CP0521198
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N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]dibenzofuran-2-carboxamide
Show/Hide
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C25H24N2O3
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1
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| 1 |
Ki = 2511.89 nM
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CP0403083
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1-(2-fluoro-benzyl)-8-(3'-hydroxy-biphenyl-4-ylmethyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C34H32FN3O4
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1
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| 1 |
Ki = 2900 nM
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CP0461513
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(S)-3-{[5-(4-Isopropoxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C26H36N4O3S
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1
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| 1 |
Ki = 3300 nM
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CP0499070
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(S)-3-{[5-(2-Methoxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H32N4O3S
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1
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| 1 |
Ki = 3400 nM
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CP0110078
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(S)-6-(4-fluorophenyl)-N-methyl-N-(6-((3-oxopiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)nicotinamide
Show/Hide
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C28H29FN4O2
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1
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| 1 |
Ki = 3465 nM
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CP0530732
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N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-3-phenylbenzamide
Show/Hide
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C28H34N2O3
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1
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| 1 |
Ki = 5011.87 nM
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CP0254319
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N-(4-fluorophenyl)-N-methyl-4-oxo-5-[2-[4-(piperidin-1-ylmethyl)phenyl]ethyl]-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxamide
Show/Hide
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C28H32FN5O2
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1
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| 1 |
Ki = 5294 nM
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CP0455683
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(S)-3-{[5-(4-Methanesulfonyl-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C24H32N4O4S2
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1
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| 1 |
Ki = 6000 nM
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CP0399505
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N-[3-[4-[[1-[(2-fluorophenyl)methyl]-3-(3-methoxyphenyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]phenyl]methanesulfonamide
Show/Hide
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C35H35FN4O5S
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1
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| 1 |
Ki = 8000 nM
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CP0045224
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(S)-4-(4-fluorophenethyl)-1-(6-((4-(trifluoromethyl)piperidin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one
Show/Hide
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C29H35F4N3O
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1
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| 1 |
Ki = 8700 nM
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CP0434141
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8-biphenyl-4-ylmethyl-1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione
Show/Hide
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C34H32FN3O3
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1
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| 1 |
Ki = 9300 nM
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CP0491865
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(S)-3-{[5-(4-Hydroxy-phenyl)-thiophene-2-carbonyl]-methyl-amino}-pyrrolidine-1-carboxylic acid methyl-((R)-1-methyl-pyrrolidin-3-yl)-amide
Show/Hide
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C23H30N4O3S
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1
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| 1 |
Ki > 10000 nM
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CP0439708
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4'-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4-dioxo-1,3,8-triaza-spiro[4.5]dec-8-ylmethyl]-biphenyl-2-carbonitrile
Show/Hide
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C35H31FN4O3
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1
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| 1 |
Ki > 10000 nM
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CP0439423
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4'-methanesulfonylamino-biphenyl-4-carboxylic acid methyl-{(S)-1-[(S)-3-(3-phenyl-propylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide
Show/Hide
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C33H41N5O4S
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1
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| 1 |
Ki > 10000 nM
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CP0254330
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(S)-4-(4-fluorophenethyl)-1-(6-(morpholinomethyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one
Show/Hide
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C27H34FN3O2
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1
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| 1 |
Ki = 15000 nM
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CP0161878
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(S)-1-(6-((4-acetylpiperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(4-fluorophenethyl)piperazin-2-one
Show/Hide
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C29H37FN4O2
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1
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| 1 |
Ki = 16000 nM
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CP0194290
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(S)-4-(4-fluorophenethyl)-1-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one
Show/Hide
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C28H37FN4O3S
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1
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| 1 |
Ki = 30000 nM
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CP0257094
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(S)-1-(6-((1H-imidazol-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(4-fluorophenethyl)piperazin-2-one
Show/Hide
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C26H29FN4O
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1
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| 1 |
Ki = 52000 nM
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CP0045228
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1-((S)-6-(((2R,6S)-2,6-dimethylpiperidin-1-yl)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(4-fluorophenethyl)piperazin-2-one
Show/Hide
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C30H40FN3O
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1
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| 1 |
Ki = 62000 nM
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CP0194291
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4-{[(6S)-6-{4-[2-(4-fluorophenyl)ethyl]-2-oxopiperazin-1-yl}-5,6,7,8-tetrahydronaphthalen-2-yl]methyl}-1,4-thiomorpholine-1,1-dione
Show/Hide
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C27H34FN3O3S
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1
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| 1 |
Ki = 94000 nM
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CP0309395
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(S)-4-(4-fluorophenethyl)-1-(6-((2,2,2-trifluoroethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one
Show/Hide
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C25H29F4N3O
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1
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| 1 |
Ki = 100000 nM
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CP0038564
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3-isopropyl-1-((2'-methoxybiphenyl-4-yl)methyl)-1-(2-(1-(4-methylbenzyl)piperidin-4-yl)ethyl)urea
Show/Hide
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C33H43N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0332299
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1-(4-biphenylmethyl)-1-(3-hydroxy-3-methyl-2-oxobutyl)-3-[1-(4-methylbenzyl)-4-piperidinyl]urea
Show/Hide
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C32H39N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0369958
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1-(3-hydroxy-3-methyl-2-oxobutyl)-1-((4'-methoxybiphenyl-4-yl)methyl)-3-(1-(4-methylbenzyl)piperidin-4-yl)urea
Show/Hide
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C33H41N3O4
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1
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| 1 |
Ki > 1000 nM
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CP0381837
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4-bromo-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]benzamide
Show/Hide
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C22H29BrN2O3
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1
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| 1 |
Ki < 6309.57 nM
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CP0529105
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N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-N-methyl-4-phenylbenzenesulfonamide
Show/Hide
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C28H36N2O4S
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1
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| 1 |
Ki < 10000 nM
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CP0529106
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3-benzoyl-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]benzamide
Show/Hide
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C29H34N2O4
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1
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| 1 |
Ki < 10000 nM
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CP0538529
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N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]benzamide
Show/Hide
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C22H30N2O3
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1
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| 1 |
Ki < 10000 nM
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CP0538530
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N-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-4-phenylbenzenesulfonamide
Show/Hide
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C25H28N2O4S
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1
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| 1 |
Ki < 10000 nM
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CP0559604
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4-tert-butyl-N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]benzamide
Show/Hide
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C26H38N2O3
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1
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| 1 |
Ki < 10000 nM
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