General Information of the Compound
Compound ID
CP0381846
Compound Name
N-[4-[2-[di(propan-2-yl)amino]ethoxy]-3-methoxyphenyl]-4-phenoxybenzamide
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Structure
Formula
C28H34N2O4
Molecular Weight
462.59
Canonical SMILES
COc1cc(NC(=O)c2ccc(Oc3ccccc3)cc2)ccc1OCCN(C(C)C)C(C)C
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InChI
InChI=1S/C28H34N2O4/c1-20(2)30(21(3)4)17-18-33-26-16-13-23(19-27(26)32-5)29-28(31)22-11-14-25(15-12-22)34-24-9-7-6-8-10-24/h6-16,19-21H,17-18H2,1-5H3,(H,29,31)
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InChIKey
ZDPLAECUGFFDLN-UHFFFAOYSA-N
Physicochemical Property
logP
6.2374
Rotatable Bonds
11
Heavy Atom Count
34
Polar Areas
60.03
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44416711
ChEMBL ID
CHEMBL215141
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 199.53 nM
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