General Information of the Compound
Compound ID
CP0554544
Compound Name
2-(3-chlorophenoxy)-N-(1-((1-(isoxazol-3-yl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
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Structure
Formula
C21H23ClN4O3
Molecular Weight
414.893
Canonical SMILES
Clc1cccc(OCC(=O)NC2CCN(Cc3ccn(c3)-c3ccon3)CC2)c1
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InChI
InChI=1S/C21H23ClN4O3/c22-17-2-1-3-19(12-17)28-15-21(27)23-18-5-8-25(9-6-18)13-16-4-10-26(14-16)20-7-11-29-24-20/h1-4,7,10-12,14,18H,5-6,8-9,13,15H2,(H,23,27)
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InChIKey
WUUMNGKLBFZACB-UHFFFAOYSA-N
Physicochemical Property
logP
3.2783
Rotatable Bonds
7
Heavy Atom Count
29
Polar Areas
72.53
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44562461
ChEMBL ID
CHEMBL507549
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1500 nM
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