Brief Information of the Compound and Protein
Compound Name
6-(5-chloropyridin-2-yl)-3-[6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
    Show/Hide
PubChem ID
CID: 45278576
SID: 92761016
Canonical SMILES
O[C@@H]1CCN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1
    Show/Hide
Compound Formula C20H17ClN6O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 124 nM
   TI
   LI
   LO
   TS