Brief Information of the Compound and Protein
Compound Name
4-N,4-N-dimethyl-2-N-[(1S,3S)-3-(thiophen-3-ylmethylamino)cyclohexyl]quinoline-2,4-diamine
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PubChem ID
CID: 44442071
Canonical SMILES
CN(C)c1cc(N[C@H]2CCC[C@@H](C2)NCc2ccsc2)nc2ccccc12
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Compound Formula C22H28N4S
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
IC50 = 97 nM
   TI
   LI
   LO
   TS