Brief Information of the Compound and Protein
Compound Name
6-(4-chlorophenyl)-3-[4-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-methoxyphenyl]pyrrolo[2,1-f][1,2,4]triazin-4-one
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PubChem ID
CID: 45279868
SID: 92762297
Canonical SMILES
COc1cc(ccc1N1C[C@H](O)[C@H](O)C1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1
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Compound Formula C23H21ClN4O4
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
2
Ki = 3.1 nM
   TI
   LI
   LO
   TS