Brief Information of the Compound and Protein
Compound Name
2-(3-chlorophenoxy)-N-((1S,5R,6s)-3-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)-3-aza-bicyclo[3.1.0]hexan-6-yl)acetamide
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Canonical SMILES
FC(F)(F)c1ccc(cc1)-n1ccc(CN2C[C@H]3[C@@H](C2)[C@@H]3NC(=O)COc2cccc(Cl)c2)c1
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Compound Formula C25H23ClF3N3O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 111 nM
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