Brief Information of the Compound and Protein
Compound Name
2-(3,4-difluorophenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)pyrrolidin-3-yl)acetamide
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PubChem ID
CID: 44562500
Canonical SMILES
Fc1ccc(OCC(=O)NC2CCN(Cc3ccn(c3)-c3ccc(cc3)C(F)(F)F)C2)cc1F
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Compound Formula C24H22F5N3O2
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
IC50 = 48 nM
   TI
   LI
   LO
   TS