Brief Information of the Compound and Protein
Compound Name
2-(4-chlorophenyl)-5-[6-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyridin-3-yl]-4H-pyrrolo[3,4-c]pyrazol-6-one
    Show/Hide
PubChem ID
CID: 46188603
SID: 96042096
Canonical SMILES
CN[C@H]1CCN(C1)c1ccc(cn1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1
    Show/Hide
Compound Formula C21H21ClN6O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 241 nM
   TI
   LI
   LO
   TS