Brief Information of the Compound and Protein
Compound Name
5-methyl-4-phenyl-1-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1H-imidazol-2(3H)-one
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PubChem ID
CID: 44562600
Canonical SMILES
Cc1c([nH]c(=O)n1C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)-c1ccccc1
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Compound Formula C27H27F3N4O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
2
IC50 = 71 nM
   TI
   LI
   LO
   TS