Brief Information of the Compound and Protein
Compound Name
(1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-((1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)methyl)cyclopentane-1,3-diamine
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PubChem ID
CID: 23657037
SID: 46529384
Canonical SMILES
COc1ccc2c(C)cc(N[C@H]3CC[C@@H](C3)NCc3cn(C)c4cccnc34)nc2c1
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Compound Formula C25H29N5O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
IC50 = 83 nM
   TI
   LI
   LO
   TS