General Information of the Compound
Compound ID
CP0394653
Compound Name
3-acetamido-4-(3,4-dimethylphenoxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
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Structure
Formula
C23H29N3O3
Molecular Weight
395.503
Canonical SMILES
CC(=O)Nc1cc(ccc1Oc1ccc(C)c(C)c1)C(=O)NCCN1CCCC1
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InChI
InChI=1S/C23H29N3O3/c1-16-6-8-20(14-17(16)2)29-22-9-7-19(15-21(22)25-18(3)27)23(28)24-10-13-26-11-4-5-12-26/h6-9,14-15H,4-5,10-13H2,1-3H3,(H,24,28)(H,25,27)
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InChIKey
GGQLFJONUYDABC-UHFFFAOYSA-N
Physicochemical Property
logP
3.87974
Rotatable Bonds
7
Heavy Atom Count
29
Polar Areas
70.67
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11710969
SID: 16815831
ChEMBL ID
CHEMBL215841
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01388, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT03304, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS