Brief Information of the Compound and Protein
Compound Name
N-[3-[4-[[1-[(2-fluorophenyl)methyl]-3-(3-methoxyphenyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]phenyl]phenyl]methanesulfonamide
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PubChem ID
CID: 44425822
Canonical SMILES
COc1cccc(c1)N1C(=O)N(Cc2ccccc2F)C2(CCN(Cc3ccc(cc3)-c3cccc(NS(C)(=O)=O)c3)CC2)C1=O
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Compound Formula C35H35FN4O5S
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 8000 nM
   TI
   LI
   LO
   TS