Compound ID |
Compound Name |
Compound Formula |
CP0482696
|
N-(12-chloro-23-methyl-22-oxo-8,19-dioxa-23-azatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-4-yl)ethanesulfonamide
Show/Hide
|
C24H25ClN2O5S
|
1
|
1 |
EC50 = 5.1 nM
|
|
|
CP0538674
|
N-(10,12-difluoro-23-methyl-22-oxo-8,19-dioxa-6,23-diazatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-4-yl)ethanesulfonamide
Show/Hide
|
C23H23F2N3O5S
|
1
|
1 |
EC50 = 6.4 nM
|
|
|
CP0538673
|
N-(10,12-difluoro-23-methyl-22-oxo-8,19-dioxa-23-azatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-4-yl)ethanesulfonamide
Show/Hide
|
C24H24F2N2O5S
|
1
|
1 |
EC50 = 6.5 nM
|
|
|
CP0567176
|
4-ethylsulfonyl-23-methyl-8,19-dioxa-23-azatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9,11,13,20-octaen-22-one
Show/Hide
|
C24H25NO5S
|
1
|
1 |
EC50 = 6.7 nM
|
|
|
CP0106552
|
US9296741, 21
Show/Hide
|
C22H21N3O4S
|
1
|
1 |
EC50 = 8.1 nM
|
|
|
CP0567179
|
N-(12-chloro-23-methyl-22-oxo-8,19-dioxa-6,23-diazatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-4-yl)ethanesulfonamide
Show/Hide
|
C23H24ClN3O5S
|
1
|
1 |
EC50 = 9.3 nM
|
|
|
CP0120224
|
US9296741, 4
Show/Hide
|
C21H19N3O4S
|
1
|
1 |
EC50 = 11 nM
|
|
|
CP0202074
|
12-chloro-4-ethylsulfonyl-23-methyl-8,19-dioxa-23-azatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-22-one
Show/Hide
|
C24H24ClNO5S
|
1
|
1 |
EC50 = 16 nM
|
|
|
CP0369516
|
N-[4-(4-chlorophenoxy)-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide
Show/Hide
|
C22H20ClN3O4S
|
1
|
1 |
EC50 = 17 nM
|
|
|
CP0227160
|
US9296741, 57
Show/Hide
|
C21H25N3O4S
|
1
|
1 |
EC50 = 18 nM
|
|
|
CP0543503
|
12-chloro-23-methyl-4-(methylsulfonylmethyl)-8,19-dioxa-23-azatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-22-one
Show/Hide
|
C24H24ClNO5S
|
1
|
1 |
EC50 = 18 nM
|
|
|
CP0153834
|
US9296741, 62
Show/Hide
|
C22H18F3N3O4S
|
1
|
1 |
EC50 = 19 nM
|
|
|
CP0069311
|
US10633379, Compound X
Show/Hide
|
C22H19F2N3O4S
|
2
|
1 |
EC50 = 20 nM
|
|
|
2 |
IC50 = 20 nM
|
|
|
CP0244069
|
US9296741, 59
Show/Hide
|
C21H23F2N3O4S
|
1
|
1 |
EC50 = 20 nM
|
|
|
CP0217104
|
US9296741, 27
Show/Hide
|
C21H17F2N3O4S
|
1
|
1 |
EC50 = 21 nM
|
|
|
CP0326185
|
US9296741, 5
Show/Hide
|
C22H18F3N3O4S
|
1
|
1 |
EC50 = 22 nM
|
|
|
CP0511722
|
12-chloro-23-methyl-4-(methylsulfonylmethyl)-8,19-dioxa-6,23-diazatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-22-one
Show/Hide
|
C23H23ClN2O5S
|
1
|
1 |
EC50 = 24 nM
|
|
|
CP0244064
|
US9296741, 6
Show/Hide
|
C22H19N3O3
|
1
|
1 |
EC50 = 26 nM
|
|
|
CP0562948
|
4-ethylsulfonyl-22-methyl-8,18-dioxa-22-azatetracyclo[17.4.0.02,7.09,14]tricosa-1(23),2(7),3,5,9,11,13,19-octaen-21-one
Show/Hide
|
C23H23NO5S
|
1
|
1 |
EC50 = 26 nM
|
|
|
CP0477221
|
N-[4-(4-chlorophenoxy)-3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C22H23ClN2O5S
|
1
|
1 |
EC50 = 27 nM
|
|
|
CP0567270
|
12-chloro-4-ethylsulfonyl-23-methyl-8,19-dioxa-6,23-diazatetracyclo[18.4.0.02,7.09,14]tetracosa-1(24),2(7),3,5,9(14),10,12,20-octaen-22-one
Show/Hide
|
C23H23ClN2O5S
|
1
|
1 |
EC50 = 34 nM
|
|
|
CP0347240
|
US9296741, 34
Show/Hide
|
C21H17ClFN3O4S
|
1
|
1 |
EC50 = 35 nM
|
|
|
CP0423161
|
N-(12-chloro-24-methyl-23-oxo-8,20-dioxa-24-azatetracyclo[19.4.0.02,7.09,14]pentacosa-1(25),2(7),3,5,9(14),10,12,21-octaen-4-yl)ethanesulfonamide
Show/Hide
|
C25H27ClN2O5S
|
1
|
1 |
EC50 = 35 nM
|
|
|
CP0198214
|
US9296741, 95
Show/Hide
|
C20H17N3O4S
|
1
|
1 |
EC50 = 39 nM
|
|
|
CP0437285
|
N-[4-(2,4-difluorophenoxy)-3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C22H22F2N2O5S
|
1
|
1 |
EC50 = 39 nM
|
|
|
CP0477220
|
N-[3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)-4-phenoxyphenyl]ethanesulfonamide
Show/Hide
|
C22H24N2O5S
|
1
|
1 |
EC50 = 39 nM
|
|
|
CP0236547
|
3-[2-(2,4-difluorophenoxy)-5-(methylsulfonylmethyl)phenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C22H18F2N2O4S
|
1
|
1 |
EC50 = 40 nM
|
|
|
CP0131103
|
US9296741, 22
Show/Hide
|
C22H22N4O4S
|
1
|
1 |
EC50 = 43 nM
|
|
|
CP0408390
|
N-[6-(2,4-difluorophenoxy)-5-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)pyridin-3-yl]ethanesulfonamide
Show/Hide
|
C21H21F2N3O5S
|
1
|
1 |
EC50 = 45 nM
|
|
|
CP0072563
|
N-[4-(2,4-difluorophenoxy)-3-(1-methyl-7-oxo-6H-pyrrolo[2,3-c]pyridin-3-yl)phenyl]methanesulfonamide
Show/Hide
|
C21H17F2N3O4S
|
1
|
1 |
EC50 = 46 nM
|
|
|
CP0311314
|
N-[4-(4-fluorophenoxy)-3-(1-methyl-7-oxo-6H-pyrrolo[2,3-c]pyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C22H20FN3O4S
|
1
|
1 |
EC50 = 47 nM
|
|
|
CP0199479
|
US9296741, 90
Show/Hide
|
C23H20N4O4S
|
1
|
1 |
EC50 = 48 nM
|
|
|
CP0494506
|
N-[4-(2,4-difluorophenoxy)-3-[1-methyl-4-(oxetan-3-yloxy)-6-oxopyridin-3-yl]phenyl]ethanesulfonamide
Show/Hide
|
C23H22F2N2O6S
|
1
|
1 |
EC50 = 48 nM
|
|
|
CP0355322
|
US9296741, 85
Show/Hide
|
C21H18N2O4S
|
1
|
1 |
EC50 = 50 nM
|
|
|
CP0082466
|
N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)-4-phenoxyphenyl]methanesulfonamide
Show/Hide
|
C22H22N2O4S
|
1
|
1 |
EC50 = 51 nM
|
|
|
CP0539347
|
N-[4-(4-cyanophenoxy)-3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C23H23N3O5S
|
1
|
1 |
EC50 = 55 nM
|
|
|
CP0326282
|
N-[4-(2,4-difluorophenoxy)-3-(1-methyl-7-oxo-6H-pyrrolo[2,3-c]pyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C22H19F2N3O4S
|
1
|
1 |
EC50 = 56 nM
|
|
|
CP0404514
|
N-[4-(2,4-difluorophenoxy)-3-(4-methoxy-1-methyl-6-oxopyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C21H20F2N2O5S
|
1
|
1 |
EC50 = 56 nM
|
|
|
CP0199478
|
N-[3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-[4-(trifluoromethyl)phenoxy]phenyl]ethanesulfonamide
Show/Hide
|
C23H20F3N3O4S
|
1
|
1 |
EC50 = 65 nM
|
|
|
CP0538672
|
5-[2-(2,4-difluorophenoxy)-5-ethylsulfonylphenyl]-4-ethoxy-1-methylpyridin-2-one
Show/Hide
|
C22H21F2NO5S
|
1
|
1 |
EC50 = 66 nM
|
|
|
CP0263573
|
US9296741, 11
Show/Hide
|
C20H18N4O4S
|
1
|
1 |
EC50 = 67 nM
|
|
|
CP0562947
|
N-[3-(4-methoxy-1-methyl-6-oxopyridin-3-yl)-4-phenoxyphenyl]ethanesulfonamide
Show/Hide
|
C21H22N2O5S
|
1
|
1 |
EC50 = 67 nM
|
|
|
CP0567268
|
N-[3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)-4-(4-fluorophenoxy)phenyl]ethanesulfonamide
Show/Hide
|
C22H23FN2O5S
|
1
|
1 |
EC50 = 69 nM
|
|
|
CP0286070
|
US9296741, 13
Show/Hide
|
C23H21N3O3
|
1
|
1 |
EC50 = 70 nM
|
|
|
CP0265296
|
US9296741, 19
Show/Hide
|
C21H17N3O3
|
1
|
1 |
EC50 = 71 nM
|
|
|
CP0102233
|
N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)phenyl]methanesulfonamide
Show/Hide
|
C22H20F2N2O4S
|
1
|
1 |
EC50 = 75 nM
|
|
|
CP0326283
|
N-[3-(7-methyl-1-oxo-2,6-dihydropyrrolo[3,4-d]pyridazin-5-yl)-4-phenoxyphenyl]ethanesulfonamide
Show/Hide
|
C21H20N4O4S
|
1
|
1 |
EC50 = 75 nM
|
|
|
CP0566085
|
N-[3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-[2-(trifluoromethyl)phenoxy]phenyl]methanesulfonamide
Show/Hide
|
C22H18F3N3O4S
|
1
|
1 |
EC50 = 76 nM
|
|
|
CP0567174
|
N-[3-(4-methoxy-1-methyl-6-oxopyridin-3-yl)-4-phenoxyphenyl]methanesulfonamide
Show/Hide
|
C20H20N2O5S
|
1
|
1 |
EC50 = 77 nM
|
|
|
CP0325482
|
US9296741, 144
Show/Hide
|
C21H27N3O4S
|
1
|
1 |
EC50 = 79 nM
|
|
|
CP0131105
|
US9296741, 23
Show/Hide
|
C20H18N4O4S
|
1
|
1 |
EC50 = 88 nM
|
|
|
CP0198210
|
US9296741, 29
Show/Hide
|
C20H23N3O5S
|
1
|
1 |
EC50 = 90 nM
|
|
|
CP0536109
|
1-methyl-3-(5-methylsulfonyl-2-phenoxyphenyl)-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C21H18N2O4S
|
1
|
1 |
EC50 = 91 nM
|
|
|
CP0389294
|
N-[4-(2,4-difluorophenoxy)-3-[1-methyl-6-oxo-4-(2,2,2-trifluoroethoxy)pyridin-3-yl]phenyl]ethanesulfonamide
Show/Hide
|
C22H19F5N2O5S
|
1
|
1 |
EC50 = 100 nM
|
|
|
CP0244071
|
US9296741, 63
Show/Hide
|
C22H21N3O4S
|
1
|
1 |
EC50 = 120 nM
|
|
|
CP0078527
|
N-[3-(3-methyl-4-oxo-2,5,6,7-tetrahydropyrrolo[3,4-c]pyridin-1-yl)-4-phenoxyphenyl]methanesulfonamide
Show/Hide
|
C21H21N3O4S
|
1
|
1 |
EC50 = 120 nM
|
|
|
CP0408389
|
N-[4-(2,4-difluorophenoxy)-3-[4-(ethylamino)-1-methyl-6-oxopyridin-3-yl]phenyl]ethanesulfonamide
Show/Hide
|
C22H23F2N3O4S
|
1
|
1 |
EC50 = 140 nM
|
|
|
CP0227914
|
3-[2-(2,4-difluorophenoxy)-5-methylsulfonylphenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C21H16F2N2O4S
|
1
|
1 |
EC50 = 150 nM
|
|
|
CP0408387
|
N-[3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)-4-pyridin-3-yloxyphenyl]ethanesulfonamide
Show/Hide
|
C21H23N3O5S
|
1
|
1 |
EC50 = 150 nM
|
|
|
CP0004236
|
(+)-JQ1
Show/Hide
|
C23H25ClN4O2S
|
1
|
1 |
EC50 = 153 nM
|
|
|
CP0217103
|
US9296741, 141
Show/Hide
|
C20H19N5O4S
|
1
|
1 |
EC50 = 170 nM
|
|
|
CP0326285
|
N-[3-(7-methyl-1-oxo-2,6-dihydropyrrolo[3,4-d]pyridazin-5-yl)-4-phenoxyphenyl]methanesulfonamide
Show/Hide
|
C20H18N4O4S
|
1
|
1 |
EC50 = 180 nM
|
|
|
CP0408388
|
N-[4-(2,4-difluorophenoxy)-3-[1-methyl-4-(2-methylpropoxy)-6-oxopyridin-3-yl]phenyl]ethanesulfonamide
Show/Hide
|
C24H26F2N2O5S
|
1
|
1 |
EC50 = 180 nM
|
|
|
CP0408386
|
N-[3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)-4-[4-(trifluoromethoxy)phenoxy]phenyl]ethanesulfonamide
Show/Hide
|
C23H23F3N2O6S
|
1
|
1 |
EC50 = 210 nM
|
|
|
CP0078526
|
7-methyl-5-(2-phenoxyphenyl)-2,6-dihydropyrrolo[3,4-d]pyridazin-1-one
Show/Hide
|
C19H15N3O2
|
1
|
1 |
EC50 = 220 nM
|
|
|
CP0539327
|
5-[2-(2,4-difluorophenoxy)-5-(methylsulfonylmethyl)phenyl]-4-ethoxy-1-methylpyridin-2-one
Show/Hide
|
C22H21F2NO5S
|
1
|
1 |
EC50 = 230 nM
|
|
|
CP0558506
|
N-[3-(4-methoxy-1-methyl-6-oxopyridazin-3-yl)-4-phenoxyphenyl]methanesulfonamide
Show/Hide
|
C19H19N3O5S
|
1
|
1 |
EC50 = 230 nM
|
|
|
CP0237899
|
N-[4-[4-(dimethylamino)cyclohexyl]oxy-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]ethanesulfonamide
Show/Hide
|
C24H32N4O4S
|
1
|
1 |
EC50 = 270 nM
|
|
|
CP0072566
|
3-methyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrahydro-4H-isoindol-4-one
Show/Hide
|
C21H19NO2
|
1
|
1 |
EC50 = 280 nM
|
|
|
CP0078524
|
N-[4-(2,4-difluorophenoxy)-3-(7-methyl-1-oxo-2,6-dihydropyrrolo[3,4-d]pyridazin-5-yl)phenyl]methanesulfonamide
Show/Hide
|
C20H16F2N4O4S
|
1
|
1 |
EC50 = 280 nM
|
|
|
CP0356978
|
3-methyl-1-(2-phenoxyphenyl)-2,5,6,7-tetrahydropyrrolo[3,4-c]pyridin-4-one
Show/Hide
|
C20H18N2O2
|
1
|
1 |
EC50 = 280 nM
|
|
|
CP0558974
|
5-[2-(4-chlorophenoxy)phenyl]-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C18H15ClN2O2
|
1
|
1 |
EC50 = 280 nM
|
|
|
CP0102231
|
1-[2-(2,4-difluorophenoxy)-5-methylsulfonylphenyl]-3-methyl-2,5,6,7-tetrahydropyrrolo[3,4-c]pyridin-4-one
Show/Hide
|
C21H18F2N2O4S
|
1
|
1 |
EC50 = 290 nM
|
|
|
CP0102234
|
1-(5-amino-2-phenoxyphenyl)-3-methyl-2,5,6,7-tetrahydro-4H-isoindol-4-one
Show/Hide
|
C21H20N2O2
|
1
|
1 |
EC50 = 300 nM
|
|
|
CP0567267
|
N-[3-(4-methoxy-1-methyl-6-oxopyridazin-3-yl)-4-phenoxyphenyl]acetamide
Show/Hide
|
C20H19N3O4
|
1
|
1 |
EC50 = 370 nM
|
|
|
CP0437005
|
N-[4-(4,4-difluorocyclohexyl)oxy-3-(4-ethoxy-1-methyl-6-oxopyridin-3-yl)phenyl]ethanesulfonamide
Show/Hide
|
C22H28F2N2O5S
|
1
|
1 |
EC50 = 390 nM
|
|
|
CP0571581
|
N-[3-(5-methyl-4-oxo-3,6-dihydropyrrolo[3,4-d]pyrimidin-7-yl)-4-phenoxyphenyl]methanesulfonamide
Show/Hide
|
C20H18N4O4S
|
1
|
1 |
EC50 = 410 nM
|
|
|
CP0468714
|
N-[4-(2,4-difluorophenoxy)-3-(3-methyl-4-oxo-2,5,6,7-tetrahydropyrrolo[3,4-c]pyridin-1-yl)phenyl]methanesulfonamide
Show/Hide
|
C21H19F2N3O4S
|
1
|
1 |
EC50 = 420 nM
|
|
|
CP0359971
|
2-methyl-5-(2-phenoxyphenyl)-1H-pyrrole-3-carboxamide
Show/Hide
|
C18H16N2O2
|
1
|
1 |
EC50 = 450 nM
|
|
|
CP0093431
|
US9296741, 1
Show/Hide
|
C20H16N2O2
|
1
|
1 |
EC50 = 480 nM
|
|
|
CP0567175
|
4-ethylsulfonyl-21-methyl-8,17-dioxa-21-azatetracyclo[16.4.0.02,7.09,14]docosa-1(22),2(7),3,5,9,11,13,18-octaen-20-one
Show/Hide
|
C22H21NO5S
|
1
|
1 |
EC50 = 630 nM
|
|
|
CP0308317
|
3-methyl-1-(2-phenoxyphenyl)-2,5-dihydropyrrolo[3,4-c]pyridin-4-one
Show/Hide
|
C20H16N2O2
|
1
|
1 |
EC50 = 700 nM
|
|
|
CP0308316
|
5-[2-(2,4-difluorophenoxy)-5-methylsulfonylphenyl]-7-methyl-2,6-dihydropyrrolo[3,4-d]pyridazin-1-one
Show/Hide
|
C20H15F2N3O4S
|
1
|
1 |
EC50 = 750 nM
|
|
|
CP0548979
|
N-[3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-(1-methylpiperidin-4-yl)oxyphenyl]ethanesulfonamide
Show/Hide
|
C22H28N4O4S
|
1
|
1 |
EC50 = 880 nM
|
|
|
CP0308318
|
5-(5-amino-2-phenoxyphenyl)-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C18H17N3O2
|
1
|
1 |
EC50 = 880 nM
|
|
|
CP0308310
|
1-methyl-3-(2-phenoxyphenyl)-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C20H16N2O2
|
1
|
1 |
EC50 = 1100 nM
|
|
|
CP0509625
|
N-[4-(2,4-difluorophenoxy)-3-[4-(2-hydroxy-2-methylpropoxy)-1-methyl-6-oxopyridin-3-yl]phenyl]ethanesulfonamide
Show/Hide
|
C24H26F2N2O6S
|
1
|
1 |
EC50 = 1100 nM
|
|
|
CP0224571
|
5-[5-(methanesulfonamido)-2-phenoxyphenyl]-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C19H19N3O4S
|
1
|
1 |
EC50 = 1400 nM
|
|
|
CP0536108
|
N-ethyl-3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindol-1-yl)-4-phenoxybenzamide
Show/Hide
|
C24H24N2O3
|
1
|
1 |
EC50 = 1400 nM
|
|
|
CP0566098
|
1-[2-(2,4-difluorophenoxy)-5-methylsulfonylphenyl]-3-methyl-2,5,6,7-tetrahydroisoindol-4-one
Show/Hide
|
C22H19F2NO4S
|
1
|
1 |
EC50 = 1400 nM
|
|
|
CP0261379
|
5-methyl-7-(2-phenoxyphenyl)-3,6-dihydropyrrolo[3,4-d]pyrimidin-4-one
Show/Hide
|
C19H15N3O2
|
1
|
1 |
EC50 = 1600 nM
|
|
|
CP0536107
|
US9776990, Example 53
Show/Hide
|
C23H21NO4
|
1
|
1 |
EC50 = 2000 nM
|
|
|
CP0536106
|
5-(2-amino-6-phenoxyphenyl)-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C18H17N3O2
|
1
|
1 |
EC50 = 2100 nM
|
|
|
CP0567269
|
N-[4-(2,4-difluorophenoxy)-3-[1-methyl-4-(2-morpholin-4-ylethoxy)-6-oxopyridin-3-yl]phenyl]ethanesulfonamide
Show/Hide
|
C26H29F2N3O6S
|
1
|
1 |
EC50 = 2200 nM
|
|
|
CP0563514
|
3-methyl-5-(2-phenoxyphenyl)-1H-pyridin-2-one
Show/Hide
|
C18H15NO2
|
1
|
1 |
EC50 = 2300 nM
|
|
|
CP0475376
|
5-[2-(2,4-difluorophenoxy)-5-(methanesulfonamido)phenyl]-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C19H17F2N3O4S
|
1
|
1 |
EC50 = 2300 nM
|
|
|
CP0308319
|
5-(2-anilinophenyl)-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C18H17N3O
|
1
|
1 |
EC50 = 2800 nM
|
|
|
CP0482694
|
1-ethyl-3-[3-(4-methoxy-1-methyl-6-oxopyridazin-3-yl)-4-phenoxyphenyl]urea
Show/Hide
|
C21H22N4O4
|
1
|
1 |
EC50 = 2800 nM
|
|
|
CP0509624
|
4-methoxy-1-methyl-5-(2-phenoxyphenyl)pyridin-2-one
Show/Hide
|
C19H17NO3
|
1
|
1 |
EC50 = 2800 nM
|
|
|
CP0494505
|
6-(5-amino-2-phenoxyphenyl)-5-methoxy-2-methylpyridazin-3-one
Show/Hide
|
C18H17N3O3
|
1
|
1 |
EC50 = 2900 nM
|
|
|
CP0408385
|
5-methoxy-2-methyl-6-(2-phenoxyphenyl)pyridazin-3-one
Show/Hide
|
C18H16N2O3
|
1
|
1 |
EC50 = 3000 nM
|
|
|
CP0198216
|
1-methyl-5-(2-phenoxyphenyl)pyridin-2-one
Show/Hide
|
C18H15NO2
|
1
|
1 |
EC50 = 4100 nM
|
|
|
CP0356979
|
5-[2-(2,4-difluorophenoxy)-5-methylsulfonylphenyl]-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C19H16F2N2O4S
|
1
|
1 |
EC50 = 4500 nM
|
|
|
CP0538671
|
ethyl N-[3-(4-methoxy-1-methyl-6-oxopyridazin-3-yl)-4-phenoxyphenyl]carbamate
Show/Hide
|
C21H21N3O5
|
1
|
1 |
EC50 = 4900 nM
|
|
|
CP0072567
|
1-(2-aminophenyl)-3-methyl-2,5,6,7-tetrahydro-4H-isoindol-4-one
Show/Hide
|
C15H16N2O
|
1
|
1 |
EC50 = 7100 nM
|
|
|
CP0244065
|
3-amino-1-methyl-5-(2-phenoxyphenyl)pyridin-2-one
Show/Hide
|
C18H16N2O2
|
1
|
1 |
EC50 = 8500 nM
|
|
|
CP0261380
|
5-(2-aminophenyl)-2-methyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C12H13N3O
|
1
|
1 |
EC50 > 10000 nM
|
|
|
CP0387151
|
8-(4-fluorophenyl)-15-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C23H20FN3O3S
|
1
|
1 |
IC50 = 1.5 nM
|
|
|
CP0069317
|
15-methyl-4-(methylsulfonylmethyl)-8-pyridin-2-yl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C22H20N4O3S
|
1
|
1 |
IC50 = 1.7 nM
|
|
|
CP0219122
|
12-methyl-4-(methylsulfonylmethyl)-8-pyridin-2-yl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C22H20N4O3S
|
1
|
1 |
IC50 = 2.3 nM
|
|
|
CP0069319
|
8-(4-fluorophenyl)-12-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C23H20FN3O3S
|
1
|
1 |
IC50 = 2.5 nM
|
|
|
CP0069312
|
8-(2,4-difluorophenyl)-15-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C23H19F2N3O3S
|
1
|
1 |
IC50 = 3.6 nM
|
|
|
CP0542881
|
8-(4,4-difluorocyclohexyl)-15-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C23H25F2N3O3S
|
1
|
1 |
IC50 = 3.7 nM
|
|
|
CP0429554
|
N-[8-(2,4-difluorophenyl)-15-methyl-14-oxo-6,8,12,15-tetrazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-4-yl]ethanesulfonamide
Show/Hide
|
C22H19F2N5O3S
|
1
|
1 |
IC50 = 4.1 nM
|
|
|
CP0542880
|
N-[8-(4-fluorophenyl)-12-methyl-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-4-yl]ethanesulfonamide
Show/Hide
|
C23H21FN4O3S
|
1
|
1 |
IC50 = 4.3 nM
|
|
|
CP0368355
|
8-(cyclopropylmethyl)-15-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C21H23N3O3S
|
1
|
1 |
IC50 = 4.6 nM
|
|
|
CP0148525
|
8-(2,4-difluorophenyl)-12-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C23H19F2N3O3S
|
1
|
1 |
IC50 = 6.5 nM
|
|
|
CP0320208
|
15-methyl-4-(methylsulfonylmethyl)-8-propanoyl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C20H21N3O4S
|
1
|
1 |
IC50 = 9 nM
|
|
|
CP0514936
|
N-(12-methyl-14-oxo-8-pyridin-2-yl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-4-yl)ethanesulfonamide
Show/Hide
|
C22H21N5O3S
|
1
|
1 |
IC50 = 18 nM
|
|
|
CP0219124
|
US9296741, 329
Show/Hide
|
C19H21N3O3S
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0320209
|
8-(cyclopropanecarbonyl)-15-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C21H21N3O4S
|
1
|
1 |
IC50 = 21 nM
|
|
|
CP0148529
|
8-(cyclopropylmethyl)-15-methyl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2,4,6,10,13(17)-hexaen-14-one
Show/Hide
|
C19H19N3O
|
1
|
1 |
IC50 = 23 nM
|
|
|
CP0515982
|
8-(cyclopropylmethyl)-15-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.014,17]heptadeca-1(16),2(7),3,5,10,14(17)-hexaen-13-one
Show/Hide
|
C21H23N3O3S
|
1
|
1 |
IC50 = 23 nM
|
|
|
CP0219123
|
8-(cyclopropylmethyl)-15-methyl-4-methylsulfonyl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C20H21N3O3S
|
1
|
1 |
IC50 = 28 nM
|
|
|
CP0578000
|
8-(cyclopropanecarbonyl)-12-methyl-4-(methylsulfonylmethyl)-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
Show/Hide
|
C21H21N3O4S
|
1
|
1 |
IC50 = 31 nM
|
|
|
CP0317868
|
N-[8-(2,4-difluorophenyl)-12-methyl-14-oxo-6,8,12,15-tetrazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-4-yl]ethanesulfonamide
Show/Hide
|
C22H19F2N5O3S
|
1
|
1 |
IC50 = 32 nM
|
|
|
CP0148526
|
methyl 12-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-8-carboxylate
Show/Hide
|
C19H19N3O5S
|
1
|
1 |
IC50 = 48 nM
|
|
|
CP0069313
|
US9296741, 328
Show/Hide
|
C20H23N3O3S
|
1
|
1 |
IC50 = 58 nM
|
|
|
CP0148528
|
8-(cyclopropylmethyl)-15-methyl-8,12,15-triazatetracyclo[8.6.1.02,7.014,17]heptadeca-1(16),2,4,6,10,14(17)-hexaen-13-one
Show/Hide
|
C19H19N3O
|
1
|
1 |
IC50 = 95 nM
|
|
|
CP0515981
|
3-[2-(cyclopropylmethylamino)-5-methylsulfonylphenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C19H21N3O3S
|
1
|
1 |
IC50 = 150 nM
|
|
|
CP0148527
|
8-(cyclopropylmethyl)-15-methyl-4-methylsulfonyl-8,12,15-triazatetracyclo[8.6.1.02,7.014,17]heptadeca-1(16),2(7),3,5,10,14(17)-hexaen-13-one
Show/Hide
|
C20H21N3O3S
|
1
|
1 |
IC50 = 190 nM
|
|
|
CP0368354
|
3-[2-(cyclopropylmethylamino)-5-(methylsulfonylmethyl)phenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C20H23N3O3S
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0097771
|
US9296741, 352
Show/Hide
|
C18H19N3O
|
1
|
1 |
IC50 = 1900 nM
|
|
|
CP0219126
|
3-[2-(cyclopropylmethylamino)phenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one
Show/Hide
|
C18H19N3O
|
1
|
1 |
IC50 = 5000 nM
|
|
|