General Information of the Cell Line
Cell Line ID
CL000792
Cell Line Name
Th17
Category
Transformed cell line
Organism
Mus musculus (Mouse)
Tissue Information
Lymph node
Disease None
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT05439, Nuclear receptor ROR-gamma
Compound ID Compound Name Compound Formula
CP0253979
US10435369, Example 137
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C26H25F8NO4S
 1
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
CP0129837
(1R,3S,4R)-4-[[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]amino]-3-methylcyclohexane-1-carboxylic acid
   Show/Hide
C29H30F8N2O4S
 1
1
EC50 = 11 nM
   TI
   LI
   LO
   TS
CP0558225
N-[3,5-dichloro-4-(6-methoxy-5-propan-2-ylpyridin-3-yl)oxyphenyl]-2-(1-methylsulfonylpiperidin-4-yl)acetamide
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C23H29Cl2N3O5S
 1
1
EC50 = 30 nM
   TI
   LI
   LO
   TS
CP0553176
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-(4-methylsulfonylpiperazin-1-yl)acetamide
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C23H29Cl2N3O5S
 1
1
EC50 = 34 nM
   TI
   LI
   LO
   TS
CP0556947
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-pyridin-4-ylacetamide
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C23H22Cl2N2O3
 1
1
EC50 = 81 nM
   TI
   LI
   LO
   TS
CP0334320
N-[1-[2-(2,4-dichlorophenyl)ethyl]indol-5-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C26H24Cl2N2O3S
 1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
CP0493777
2-(4-ethylsulfonylphenyl)-N-[1-[2-[4-(trifluoromethyl)phenyl]ethyl]indol-5-yl]acetamide
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C27H25F3N2O3S
 1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
CP0493776
N-[1-[2-(3,4-dichlorophenyl)ethyl]indol-5-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C26H24Cl2N2O3S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0486773
2-(4-ethylsulfonylphenyl)-N-[1-[2-(4-propan-2-yloxyphenyl)ethyl]indol-5-yl]acetamide
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C29H32N2O4S
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0066901
N-[5-[4-chloro-2-(trifluoromethyl)phenoxy]-4-(3-cyanophenyl)-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C27H19ClF3N3O4S2
 1
1
IC50 = 158.49 nM
   TI
   LI
   LO
   TS
CP0538990
N-[1-[2-(4-chlorophenyl)ethyl]indol-5-yl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C26H25ClN2O3S
 1
1
IC50 = 164 nM
   TI
   LI
   LO
   TS
CP0059071
N-[4-(3-cyanophenyl)-5-[2-(trifluoromethyl)phenoxy]-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C27H20F3N3O4S2
 1
1
IC50 = 251.19 nM
   TI
   LI
   LO
   TS
CP0066706
2-(4-ethylsulfonylphenyl)-N-[5-(2-methoxyphenoxy)-4-phenyl-1,3-thiazol-2-yl]acetamide
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C26H24N2O5S2
 1
1
IC50 = 251.19 nM
   TI
   LI
   LO
   TS
CP0519322
2-(4-ethylsulfonylphenyl)-N-[4-[[propyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]phenyl]acetamide
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C28H31F3N2O3S
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0059072
N-[5-[2-chloro-4-(trifluoromethyl)phenoxy]-4-(3-cyanophenyl)-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C27H19ClF3N3O4S2
 1
1
IC50 = 398.11 nM
   TI
   LI
   LO
   TS
CP0519321
N-[1-[2-(4-cyanophenyl)ethyl]indol-5-yl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C27H25N3O3S
 1
1
IC50 = 457 nM
   TI
   LI
   LO
   TS
CP0175161
2-(4-ethylsulfonylphenyl)-N-[4-phenyl-5-[4-(trifluoromethyl)phenoxy]-1,3-thiazol-2-yl]acetamide
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C26H21F3N2O4S2
 1
1
IC50 = 630.96 nM
   TI
   LI
   LO
   TS
CP0486774
2-(4-ethylsulfonylphenyl)-N-[4-[propyl-[2-[4-(trifluoromethyl)phenyl]ethyl]amino]phenyl]acetamide
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C28H31F3N2O3S
 1
1
IC50 = 733 nM
   TI
   LI
   LO
   TS
CP0247829
2-(4-ethylsulfonylphenyl)-N-[4-phenyl-5-[2-(trifluoromethyl)phenoxy]-1,3-thiazol-2-yl]acetamide
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C26H21F3N2O4S2
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0420736
N-[3-chloro-4-[2-[4-(trifluoromethyl)phenyl]ethylamino]phenyl]-2-(4-ethylsulfonylphenyl)acetamide
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C25H24ClF3N2O3S
 1
1
IC50 = 1023 nM
   TI
   LI
   LO
   TS
CP0059070
N-[4-(3-chlorophenyl)-5-phenoxy-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C25H21ClN2O4S2
 1
1
IC50 = 1584.89 nM
   TI
   LI
   LO
   TS
CP0066703
N-[5-(4-chlorophenoxy)-4-phenyl-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C25H21ClN2O4S2
 1
1
IC50 = 1584.89 nM
   TI
   LI
   LO
   TS
CP0067836
N-[5-(2-chlorophenoxy)-4-phenyl-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C25H21ClN2O4S2
 1
1
IC50 = 1584.89 nM
   TI
   LI
   LO
   TS
CP0101927
N-[4-(3-chlorophenyl)-5-[2-(trifluoromethyl)phenoxy]-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C26H20ClF3N2O4S2
 1
1
IC50 = 1995.26 nM
   TI
   LI
   LO
   TS
CP0071666
N-[4-(4-chlorophenyl)-5-phenoxy-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
   Show/Hide
C25H21ClN2O4S2
 1
1
IC50 = 3981.07 nM
   TI
   LI
   LO
   TS
CP0514635
2-(4-ethylsulfonylphenyl)-N-[4-[[[4-(trifluoromethyl)phenyl]methylamino]methyl]phenyl]acetamide
   Show/Hide
C25H25F3N2O3S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0066702
2-(4-ethylsulfonylphenyl)-N-[5-(4-methoxyphenoxy)-4-phenyl-1,3-thiazol-2-yl]acetamide
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C26H24N2O5S2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lymph node)
Cell Line Name Organism Disease
AN3-CA Homo sapiens (Human) Acanthosis nigricans--NCIt; C7359; Endometrial adenocarcinoma
A2058 Homo sapiens (Human) Amelanotic melanoma
LOX-IMVI Homo sapiens (Human) Amelanotic melanoma
SW620 Homo sapiens (Human) Colon adenocarcinoma
SW620/AD300 Homo sapiens (Human) Colon adenocarcinoma
LoVo Homo sapiens (Human) Colon adenocarcinoma
SK-MEL-5 Homo sapiens (Human) Cutaneous melanoma
SU-DHL-5 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HOC313 Homo sapiens (Human) Floor of mouth squamous cell carcinoma
HGC-27 Homo sapiens (Human) Gastric carcinoma
NUGC-4 Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
NCI-H1993 Homo sapiens (Human) Lung adenocarcinoma
PC-9 Homo sapiens (Human) Lung adenocarcinoma
NCI-H838 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1568 Homo sapiens (Human) Lung adenocarcinoma
PC9-DRH Homo sapiens (Human) Lung adenocarcinoma
NCI-H2009 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1299 Homo sapiens (Human) Lung large cell carcinoma
NCI-H1155 Homo sapiens (Human) Lung large cell carcinoma
NCI-H292 Homo sapiens (Human) Lung mucoepidermoid carcinoma
HBL-2 [Human mantle cell lymphoma] Homo sapiens (Human) Mantle cell lymphoma
MNT-1 Homo sapiens (Human) Melanoma
JR8 Homo sapiens (Human) Melanoma
MM96L Homo sapiens (Human) Melanoma
WM3629 Homo sapiens (Human) Melanoma
L3.6pl Homo sapiens (Human) Pancreatic adenosquamous carcinoma
LNCaP Homo sapiens (Human) Prostate carcinoma
LAPC-4 Homo sapiens (Human) Prostate carcinoma
LNCaP-AR Homo sapiens (Human) Prostate carcinoma
LNCaP C4-2 Homo sapiens (Human) Prostate carcinoma
MR49F Homo sapiens (Human) Prostate carcinoma
LNCaP-hr Homo sapiens (Human) Prostate carcinoma
LNCap-ARR2PB-eGFP Homo sapiens (Human) Prostate carcinoma