General Information of the Cell Line
Cell Line ID
CL000098
Cell Line Name
A2058
Synonyms
A 2058
A-2058
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1059
Tissue Information
Lymph node
Disease
Amelanotic melanoma (NCIt: C3802)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01786, Autotaxin
 Protein Info 
Compound ID Compound Name Compound Formula
CP0082479
 Compound Info 
2,4-dichloro-5-morpholin-4-ylsulfonyl-N-(3,4,5-trifluorophenyl)benzenecarbothioamide
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C17H13Cl2F3N2O3S2
  1
1
IC50 = 403 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0526186
 Compound Info 
2,4-dichloro-N-(3,4-difluorophenyl)-5-morpholin-4-ylsulfonylbenzamide
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C17H14Cl2F2N2O4S
  1
1
IC50 = 528 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0248462
 Compound Info 
2,4-dichloro-N-(4-chloro-3,5-difluorophenyl)-5-morpholin-4-ylsulfonylbenzamide
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C17H13Cl3F2N2O4S
  1
1
IC50 = 740.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0260174
 Compound Info 
2,4-dichloro-5-morpholin-4-ylsulfonyl-N-(3,4,5-trifluorophenyl)benzamide
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C17H13Cl2F3N2O4S
  1
1
IC50 = 1478 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0008108
 Compound Info 
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-hydroxy(phenyl)methyl]oxolane-3,4-diol
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 C17H18N4O4  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CP0013606
 Compound Info 
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
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 C17H20F3N7O2  1
1
IC50 = 2333 nM
   TI
   LI
   LO
   TS
CP0454796
 Compound Info 
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-3-(trifluoromethyl)pyridin-2-amine
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 C17H20F3N7O2  1
1
IC50 > 20000 nM
   TI
   LI
   LO
   TS
CP0456424
 Compound Info 
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)pyridin-2-amine
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 C16H21N7O2  1
1
IC50 = 3819 nM
   TI
   LI
   LO
   TS
CP0476128
 Compound Info 
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-methylpyrimidin-2-amine
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 C16H22N8O2  1
1
IC50 = 2934 nM
   TI
   LI
   LO
   TS
CP0508404
 Compound Info 
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-3-methylpyridin-2-amine
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 C17H23N7O2  1
1
IC50 = 14210 nM
   TI
   LI
   LO
   TS
CP0567096
 Compound Info 
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-N-methoxy-4-(trifluoromethyl)pyridin-2-amine
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 C18H22F3N7O3  1
1
IC50 = 19200 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lymph node)
Cell Line Name Organism Disease
AN3-CA
 Cell Line Info 
Homo sapiens (Human) Acanthosis nigricans--NCIt; C7359; Endometrial adenocarcinoma
LOX-IMVI
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SW620
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW620/AD300
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LoVo
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SK-MEL-5
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
SU-DHL-5
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HOC313
 Cell Line Info 
Homo sapiens (Human) Floor of mouth squamous cell carcinoma
HGC-27
 Cell Line Info 
Homo sapiens (Human) Gastric carcinoma
NUGC-4
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
NCI-H1993
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC-9
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H838
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1568
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC9-DRH
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2009
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1299
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H1155
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H292
 Cell Line Info 
Homo sapiens (Human) Lung mucoepidermoid carcinoma
HBL-2 [Human mantle cell lymphoma]
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
MNT-1
 Cell Line Info 
Homo sapiens (Human) Melanoma
JR8
 Cell Line Info 
Homo sapiens (Human) Melanoma
MM96L
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM3629
 Cell Line Info 
Homo sapiens (Human) Melanoma
L3.6pl
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenosquamous carcinoma
LNCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LAPC-4
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP C4-2
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MR49F
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-hr
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCap-ARR2PB-eGFP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
Th17
 Cell Line Info 
Mus musculus (Mouse) -