General Information of the Cell Line
Cell Line ID
CL000104
Cell Line Name
SW620
Synonyms
SW-620
SW 620
SW.620
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0547
Tissue Information
Lymph node
Disease
Colon adenocarcinoma (NCIt: C4349)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01975, Cyclin-dependent kinase 8
 Protein Info 
Compound ID Compound Name Compound Formula
CP0016718
 Compound Info 
8-[6-(2-methoxyethylcarbamoyl)-2-methylpyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C20H20N4O4S2
  1
1
EC50 = 0.35 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0027462
 Compound Info 
8-(6-acetamidopyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C17H14N4O3S2
  1
1
EC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016912
 Compound Info 
8-[6-(methylamino)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H14N4O2S2
  1
1
EC50 = 0.58 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0024578
 Compound Info 
8-phenoxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H12N2O2S2
  1
1
EC50 = 0.77 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0023952
 Compound Info 
8-[6-(2-methoxyethylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C19H18N4O4S2
  1
1
EC50 = 1.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0030415
 Compound Info 
8-(6-carbamoylpyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H12N4O3S2
  1
1
EC50 = 1.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016917
 Compound Info 
8-[6-(2-ethoxyethylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C20H20N4O4S2
  1
1
EC50 = 1.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0027478
 Compound Info 
8-(2-methylpyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H13N3O2S2
  1
1
EC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016918
 Compound Info 
8-(6-aminopyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C15H12N4O2S2
  1
1
EC50 = 2.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029602
 Compound Info 
8-[6-(methylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C17H14N4O3S2
  1
1
EC50 = 2.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029592
 Compound Info 
8-(6-methylpyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H13N3O2S2
  1
1
EC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0030416
 Compound Info 
8-pyridin-3-yloxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C15H11N3O2S2
  1
1
EC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0022922
 Compound Info 
8-[6-[(2-hydroxy-2-methylpropyl)carbamoyl]pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C20H20N4O4S2
  1
1
EC50 = 7.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016911
 Compound Info 
8-(2-methyl-1-oxidopyridin-1-ium-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H13N3O3S2
  1
1
EC50 = 8.3 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0021499
 Compound Info 
8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C11H10N2OS3
  1
1
EC50 = 8.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0024801
 Compound Info 
8-methoxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C11H10N2O2S2
  1
1
EC50 = 9.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016919
 Compound Info 
8-(4-methylpyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H13N3O2S2
  1
1
EC50 = 16 nM
 Bioactivity Info 
   TI
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CP0027468
 Compound Info 
8-[6-(dimethylcarbamoyl)pyridin-3-yl]oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C18H16N4O3S2
  1
1
EC50 = 21 nM
 Bioactivity Info 
   TI
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   LO
   TS
CP0022319
 Compound Info 
1-methyl-8-methylsulfanyl-4,5-dihydrothieno[3,4-g]indazole-6-carboxamide
   Show/Hide
C12H13N3OS2
  1
1
EC50 = 25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0023949
 Compound Info 
8-(5-methylpyridin-3-yl)oxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H13N3O2S2
  1
1
EC50 = 28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0022318
 Compound Info 
8-pyridin-2-yloxy-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C15H11N3O2S2
  1
1
EC50 = 66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0027460
 Compound Info 
8-methylsulfinyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C11H10N2O2S3
  1
1
EC50 = 70 nM
 Bioactivity Info 
   TI
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   LO
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CP0029601
 Compound Info 
N-methyl-8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C12H12N2OS3
  1
1
EC50 = 140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0020244
 Compound Info 
8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzoxazole-6-carboxamide
   Show/Hide
C11H10N2O2S2
  1
1
EC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0032209
 Compound Info 
8-methylsulfonyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C11H10N2O3S3
  1
1
EC50 = 220 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0030137
 Compound Info 
8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carbonitrile
   Show/Hide
C11H8N2S3
  1
1
EC50 = 490 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016915
 Compound Info 
8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2,3]benzothiadiazole-6-carboxamide
   Show/Hide
C10H9N3OS3
  1
1
EC50 = 550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0027461
 Compound Info 
8-methylsulfanyl-N-(1,2-thiazol-3-yl)-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C14H11N3OS4
  1
1
EC50 = 620 nM
 Bioactivity Info 
   TI
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   TS
CP0027479
 Compound Info 
8-methylsulfanyl-N-(1,2-oxazol-3-yl)-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C14H11N3O2S3
  1
1
EC50 = 890 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0016916
 Compound Info 
8-methylsulfanyl-4,5-dihydro-1H-thieno[3,4-g]indazole-6-carboxamide
   Show/Hide
C11H11N3OS2
  1
1
EC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0023950
 Compound Info 
N-(1-methylpyrazol-3-yl)-8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C15H14N4OS3
  1
1
EC50 = 1400 nM
 Bioactivity Info 
   TI
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CP0030140
 Compound Info 
N,N-dimethyl-8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C13H14N2OS3
  1
1
EC50 = 1700 nM
 Bioactivity Info 
   TI
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CP0020240
 Compound Info 
8-methylsulfanyl-N-pyridin-2-yl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C16H13N3OS3
  1
1
EC50 = 2800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0022561
 Compound Info 
2-methyl-8-methylsulfanyl-4,5-dihydrothieno[3,4-g]indazole-6-carboxamide
   Show/Hide
C12H13N3OS2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0023951
 Compound Info 
8-methylsulfanyl-N-phenyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxamide
   Show/Hide
C17H14N2OS3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0029593
 Compound Info 
8-methylsulfanyl-4,5-dihydrothieno[3,4-g][1,2]benzothiazole-6-carboxylic acid
   Show/Hide
C11H9NO2S3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
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CP0001577
 Compound Info 
N-methyl-3-[(1-methylindazol-5-yl)methyl]-2H-indazole-5-carboxamide
   Show/Hide
C18H17N5O
  1
1
IC50 = 49 nM
 Bioactivity Info 
   TI
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Protein ID: PT06808, Na(+)/H(+) exchange regulatory cofactor NHE-RF1
 Protein Info 
Protein ID: PT05574, Palmitoleoyl-protein carboxylesterase NOTUM
 Protein Info 
Protein ID: PT04124, Proteinase-activated receptor 2
 Protein Info 
Protein ID: PT00865, Serine/threonine-protein kinase Chk1
 Protein Info 
Protein ID: PT01466, Telomerase reverse transcriptase
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0007711
 Compound Info 
(E)-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-N'-propylprop-2-enehydrazide;2,2,2-trifluoroacetic acid
   Show/Hide
 C26H31F3N4O3  1
1
LC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0035025
 Compound Info 
4-anilinoquinazoline deriv. 2
   Show/Hide
 C17H13BrN4O  1
1
IC50 = 8230 nM
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CP0042443
 Compound Info 
(S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophen-2-yl)urea
   Show/Hide
 C17H20N4O2S  1
1
GI50 = 839 nM
   TI
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CP0064592
 Compound Info 
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
   Show/Hide
 C47H51NO14  1
1
GI50 = 4 nM
   TI
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CP0066302
 Compound Info 
(E)-1-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7,8-dihydropyrimido[5,4-g][1,4]benzoxazin-6-yl]-4-(dimethylamino)but-2-en-1-one
   Show/Hide
 C29H27ClFN5O3  1
1
IC50 = 6200 nM
   TI
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   TS
CP0076082
 Compound Info 
N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
   Show/Hide
 C22H18N4O2S3  1
1
EC50 = 1900 nM
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CP0077619
 Compound Info 
Andrographolide
   Show/Hide
 C20H30O5  1
1
GI50 = 3000 nM
   TI
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CP0082019
 Compound Info 
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
   Show/Hide
 C22H21NO2S  1
1
GI50 = 1580 nM
   TI
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CP0148456
 Compound Info 
(2R)-2-amino-3-[(4-methoxyphenyl)-diphenylmethyl]sulfanylpropan-1-ol
   Show/Hide
 C23H25NO2S  1
1
GI50 = 70 nM
   TI
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CP0292135
 Compound Info 
4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile
   Show/Hide
 C18H13ClFN3O2  1
1
IC50 = 9890 nM
   TI
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CP0383276
 Compound Info 
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
   Show/Hide
 C16H17N3O2  1
1
GI50 = 29.8 nM
   TI
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CP0389175
 Compound Info 
2-(1H-benzimidazol-2-ylmethylsulfanyl)-5-phenyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
   Show/Hide
 C19H14N6OS  3
1
IC50 = 6.32 nM
   TI
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2
IC50 = 6.79 nM
   TI
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3
IC50 = 1576.68 nM
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CP0389966
 Compound Info 
8-[2-(4-propan-2-ylphenyl)-3H-benzimidazole-5-carbonyl]-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
   Show/Hide
 C32H31F3N4O2  1
1
IC50 > 10000 nM
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CP0396933
 Compound Info 
(3S,3'S,7R,8R,8aS)-2-acetyl-3-benzyl-8-(7-methoxy-1,3-benzodioxol-5-yl)-3'-phenylspiro[3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazine-7,2'-oxirane]-6-one
   Show/Hide
 C31H30N2O6  1
1
IC50 > 30000 nM
   TI
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CP0415607
 Compound Info 
8-(2-phenyl-3H-benzimidazole-5-carbonyl)-2-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decan-3-one
   Show/Hide
 C29H25F3N4O2  1
1
IC50 = 2050 nM
   TI
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CP0415608
 Compound Info 
methyl 4-[8-(7-methyl-1H-indazole-5-carbonyl)-3-oxo-2,8-diazaspiro[4.5]decan-2-yl]benzoate
   Show/Hide
 C25H26N4O4  1
1
IC50 > 10000 nM
   TI
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CP0465282
 Compound Info 
4-N-(4-methoxyphenyl)-4-N-methyl-9H-pyrimido[4,5-b]indole-2,4-diamine
   Show/Hide
 C18H17N5O  1
1
GI50 = 19 nM
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CP0504740
 Compound Info 
4-(6-methoxy-3,4-dihydro-2H-quinolin-1-yl)-2,6-dimethylfuro[2,3-d]pyrimidine
   Show/Hide
 C18H19N3O2  1
1
GI50 < 10 nM
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CP0541597
 Compound Info 
(3S,7E,8S,8aS)-2-acetyl-7-benzylidene-8-(7-methoxy-1,3-benzodioxol-5-yl)-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
   Show/Hide
 C33H32N2O8  1
1
IC50 > 30000 nM
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CP0634648
 Compound Info 
N-((R)-Cyclopropyl(pyridin-2-yl)methyl)-3-(4-((endo)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)phenyl)-1H-indazole-5-carboxamide
   Show/Hide
 C30H31N5O2  1
1
GI50 = 30 nM
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CP0894107
 Compound Info 
(2R,3R)-ethyl 3-(4-(3-bromoanilino)quinazolin-6-ylcarbamoyl)oxirane-2-carboxylate
   Show/Hide
 C18H13BrN4O4  1
1
IC50 > 10000 nM
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CP0897293
 Compound Info 
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
   Show/Hide
 C24H25ClN4O  1
1
GI50 = 370 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lymph node)
Cell Line Name Organism Disease
AN3-CA
 Cell Line Info 
Homo sapiens (Human) Acanthosis nigricans--NCIt; C7359; Endometrial adenocarcinoma
A2058
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
LOX-IMVI
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SW620/AD300
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LoVo
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SK-MEL-5
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
SU-DHL-5
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HOC313
 Cell Line Info 
Homo sapiens (Human) Floor of mouth squamous cell carcinoma
HGC-27
 Cell Line Info 
Homo sapiens (Human) Gastric carcinoma
NUGC-4
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
NCI-H1993
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC-9
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H838
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1568
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC9-DRH
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2009
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1299
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H1155
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H292
 Cell Line Info 
Homo sapiens (Human) Lung mucoepidermoid carcinoma
HBL-2 [Human mantle cell lymphoma]
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
MNT-1
 Cell Line Info 
Homo sapiens (Human) Melanoma
JR8
 Cell Line Info 
Homo sapiens (Human) Melanoma
MM96L
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM3629
 Cell Line Info 
Homo sapiens (Human) Melanoma
L3.6pl
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenosquamous carcinoma
LNCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LAPC-4
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP C4-2
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MR49F
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-hr
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCap-ARR2PB-eGFP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
Th17
 Cell Line Info 
Mus musculus (Mouse) -