General Information of the Cell Line
Cell Line ID
CL000563
Cell Line Name
NCI-H1568
Synonyms
H1568
H-1568
NCIH1568
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1476
Tissue Information
Lymph node
Disease
Lung adenocarcinoma (NCIt: C3512)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT03381, 5'-nucleotidase
Compound ID Compound Name Compound Formula
CP0426496
[(2R)-2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1-hydroxy-3-methoxypropan-2-yl]phosphonic acid
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C19H29ClN5O9P
 1
1
EC50 = 0.79 nM
   TI
   LI
   LO
   TS
CP0135378
[[(2R,3S,4R,5R)-5-[6-chloro-4-[[(1S)-1-(2-fluorophenyl)ethyl]amino]pyrazolo[3,4-b]pyridin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acid
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C20H24ClFN4O9P2
 1
1
EC50 = 3.3 nM
   TI
   LI
   LO
   TS
CP0466407
[2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1,3-dihydroxypropan-2-yl]phosphonic acid
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C18H27ClN5O9P
 1
1
EC50 = 3.7 nM
   TI
   LI
   LO
   TS
CP0426495
[(2R)-2-[[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy]-1-hydroxypropan-2-yl]phosphonic acid
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C18H27ClN5O8P
 1
1
EC50 = 6.9 nM
   TI
   LI
   LO
   TS
CP0136183
ADP, alpha beta-me
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C11H17N5O9P2
 1
1
EC50 = 16268 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lymph node)
Cell Line Name Organism Disease
AN3-CA Homo sapiens (Human) Acanthosis nigricans--NCIt; C7359; Endometrial adenocarcinoma
A2058 Homo sapiens (Human) Amelanotic melanoma
LOX-IMVI Homo sapiens (Human) Amelanotic melanoma
SW620 Homo sapiens (Human) Colon adenocarcinoma
SW620/AD300 Homo sapiens (Human) Colon adenocarcinoma
LoVo Homo sapiens (Human) Colon adenocarcinoma
SK-MEL-5 Homo sapiens (Human) Cutaneous melanoma
SU-DHL-5 Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HOC313 Homo sapiens (Human) Floor of mouth squamous cell carcinoma
HGC-27 Homo sapiens (Human) Gastric carcinoma
NUGC-4 Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
NCI-H1993 Homo sapiens (Human) Lung adenocarcinoma
PC-9 Homo sapiens (Human) Lung adenocarcinoma
NCI-H838 Homo sapiens (Human) Lung adenocarcinoma
PC9-DRH Homo sapiens (Human) Lung adenocarcinoma
NCI-H2009 Homo sapiens (Human) Lung adenocarcinoma
NCI-H1299 Homo sapiens (Human) Lung large cell carcinoma
NCI-H1155 Homo sapiens (Human) Lung large cell carcinoma
NCI-H292 Homo sapiens (Human) Lung mucoepidermoid carcinoma
HBL-2 [Human mantle cell lymphoma] Homo sapiens (Human) Mantle cell lymphoma
MNT-1 Homo sapiens (Human) Melanoma
JR8 Homo sapiens (Human) Melanoma
MM96L Homo sapiens (Human) Melanoma
WM3629 Homo sapiens (Human) Melanoma
L3.6pl Homo sapiens (Human) Pancreatic adenosquamous carcinoma
LNCaP Homo sapiens (Human) Prostate carcinoma
LAPC-4 Homo sapiens (Human) Prostate carcinoma
LNCaP-AR Homo sapiens (Human) Prostate carcinoma
LNCaP C4-2 Homo sapiens (Human) Prostate carcinoma
MR49F Homo sapiens (Human) Prostate carcinoma
LNCaP-hr Homo sapiens (Human) Prostate carcinoma
LNCap-ARR2PB-eGFP Homo sapiens (Human) Prostate carcinoma
Th17 Mus musculus (Mouse) -