General Information of the Cell Line
Cell Line ID
CL000888
Cell Line Name
LNCaP-hr
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0395
Tissue Information
Lymph node
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00894, Androgen receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0044960
 Compound Info 
(1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-5-one
   Show/Hide
C19H30O2
  2
1
EC50 = 6.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 15 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385183
 Compound Info 
2-chloro-4-[(2S,3R)-3-(4-fluorophenyl)-3-hydroxy-2-methylpyrrolidin-1-yl]benzonitrile
   Show/Hide
C18H16ClFN2O
  2
1
EC50 = 20 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391690
 Compound Info 
2-chloro-4-(3-hydroxypyrrolidin-1-yl)benzonitrile
   Show/Hide
C11H11ClN2O
  2
1
EC50 = 640 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 4700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391689
 Compound Info 
4-(3-benzyl-3-hydroxypyrrolidin-1-yl)-2-chlorobenzonitrile
   Show/Hide
C18H17ClN2O
  2
1
EC50 = 4800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385187
 Compound Info 
6-[(2S,3S)-1-(3-chloro-4-cyanophenyl)-3-hydroxy-2-methylpyrrolidin-3-yl]-N-methylpyridine-3-carboxamide
   Show/Hide
C19H19ClN4O2
  2
1
EC50 = 5100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0146696
 Compound Info 
Bicalutamide
   Show/Hide
C18H14F4N2O4S
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385184
 Compound Info 
4-[(2S,3R)-1-(3-chloro-4-cyanophenyl)-3-hydroxy-2-methylpyrrolidin-3-yl]-N-methylbenzamide
   Show/Hide
C20H20ClN3O2
  2
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385185
 Compound Info 
2-chloro-4-[3-(4-fluorophenyl)-3-hydroxypyrrolidin-1-yl]benzonitrile
   Show/Hide
C17H14ClFN2O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385186
 Compound Info 
5-[(2S,3R)-1-(3-chloro-4-cyanophenyl)-3-hydroxy-2-methylpyrrolidin-3-yl]-N-methylpyridine-2-carboxamide
   Show/Hide
C19H19ClN4O2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391672
 Compound Info 
5-[(2R,3S)-1-(3-chloro-4-cyanophenyl)-3-hydroxy-2-methylpyrrolidin-3-yl]-N-methylpyridine-2-carboxamide
   Show/Hide
C19H19ClN4O2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391673
 Compound Info 
4-[(2S,3R)-1-(3-chloro-4-cyanophenyl)-3-hydroxy-2-methylpyrrolidin-3-yl]benzamide
   Show/Hide
C19H18ClN3O2
  2
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391674
 Compound Info 
5-[(2S,3R)-1-(3-chloro-4-cyanophenyl)-3-hydroxy-2-methylpyrrolidin-3-yl]-N,N-dimethylpyridine-2-carboxamide
   Show/Hide
C20H21ClN4O2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0449090
 Compound Info 
2-chloro-4-(3-hydroxy-3-phenylpyrrolidin-1-yl)benzonitrile
   Show/Hide
C17H15ClN2O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lymph node)
Cell Line Name Organism Disease
AN3-CA
 Cell Line Info 
Homo sapiens (Human) Acanthosis nigricans--NCIt; C7359; Endometrial adenocarcinoma
A2058
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
LOX-IMVI
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SW620
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW620/AD300
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LoVo
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SK-MEL-5
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
SU-DHL-5
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HOC313
 Cell Line Info 
Homo sapiens (Human) Floor of mouth squamous cell carcinoma
HGC-27
 Cell Line Info 
Homo sapiens (Human) Gastric carcinoma
NUGC-4
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
NCI-H1993
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC-9
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H838
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1568
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC9-DRH
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2009
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1299
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H1155
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H292
 Cell Line Info 
Homo sapiens (Human) Lung mucoepidermoid carcinoma
HBL-2 [Human mantle cell lymphoma]
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
MNT-1
 Cell Line Info 
Homo sapiens (Human) Melanoma
JR8
 Cell Line Info 
Homo sapiens (Human) Melanoma
MM96L
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM3629
 Cell Line Info 
Homo sapiens (Human) Melanoma
L3.6pl
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenosquamous carcinoma
LNCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LAPC-4
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP C4-2
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MR49F
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCap-ARR2PB-eGFP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
Th17
 Cell Line Info 
Mus musculus (Mouse) -