General Information of the Cell Line
Cell Line ID
CL000521
Cell Line Name
LAPC-4
Synonyms
LAPC4
Los Angeles Prostate Cancer-4
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_4744
Tissue Information
Lymph node
Disease
Prostate carcinoma (NCIt: C4863)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00894, Androgen receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0565134
 Compound Info 
1-ethyl-3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C14H14F4N2O2
  1
1
IC50 = 140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0317458
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
   Show/Hide
C10H6F4N2O2
  1
1
IC50 = 260 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552074
 Compound Info 
2-[3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl]acetonitrile
   Show/Hide
C14H11F4N3O2
  1
1
IC50 = 290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077490
 Compound Info 
5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin
   Show/Hide
C12H10F3N3O4
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0261257
 Compound Info 
1-[4-fluoro-3-(trifluoromethyl)phenyl]-3,3-dimethylpyrrolidine-2,5-dione
   Show/Hide
C13H11F4NO2
  1
1
IC50 = 910 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0224987
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.4]nonane-2,4-dione
   Show/Hide
C14H12F4N2O2
  1
1
IC50 = 990 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0274366
 Compound Info 
5,5-dimethyl-3-quinolin-4-ylimidazolidine-2,4-dione
   Show/Hide
C14H13N3O2
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0317461
 Compound Info 
3-[4-chloro-3-(trifluoromethyl)phenyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C12H10ClF3N2O2
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557320
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,5,5-trimethylimidazolidine-2,4-dione
   Show/Hide
C13H12F4N2O2
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564940
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethyl-1,3-oxazolidine-2,4-dione
   Show/Hide
C12H9F4NO3
  1
1
IC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0488998
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethyl-1-(2-phenylethyl)imidazolidine-2,4-dione
   Show/Hide
C20H18F4N2O2
  1
1
IC50 = 2400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0344856
 Compound Info 
1-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C12H10F4N2O2
  1
1
IC50 = 2800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0575758
 Compound Info 
2-[[4-fluoro-3-(trifluoromethyl)phenyl]carbamoylamino]-2-methylpropanoic acid
   Show/Hide
C12H12F4N2O3
  1
1
IC50 = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577643
 Compound Info 
2-[4-fluoro-3-(trifluoromethyl)phenyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione
   Show/Hide
C13H10F4N2O2
  1
1
IC50 = 3500 nM
 Bioactivity Info 
   TI
   LI
   LO
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CP0470077
 Compound Info 
5-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-fluorobenzonitrile
   Show/Hide
C12H10FN3O2
  1
1
IC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552088
 Compound Info 
5,5-dimethyl-3-pyridin-4-ylimidazolidine-2,4-dione
   Show/Hide
C10H11N3O2
  1
1
IC50 = 3800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0470074
 Compound Info 
3-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C13H12F4N2O2
  1
1
IC50 = 4200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564941
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decane-2,4-dione
   Show/Hide
C15H14F4N2O2
  1
1
IC50 = 4200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0488997
 Compound Info 
1-(benzenesulfonyl)-3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C18H14F4N2O4S
  1
1
IC50 = 4300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528435
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C12H10F4N2O2
  1
1
IC50 = 4400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0564942
 Compound Info 
5,5-dimethyl-3-[2-(trifluoromethyl)pyridin-4-yl]imidazolidine-2,4-dione
   Show/Hide
C11H10F3N3O2
  1
1
IC50 = 4500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557188
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(hydroxymethyl)-5-methylimidazolidine-2,4-dione
   Show/Hide
C12H10F4N2O3
  1
1
IC50 = 4800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565117
 Compound Info 
(5R)-3-[3-(difluoromethyl)-4-fluorophenyl]-5-phenylimidazolidine-2,4-dione
   Show/Hide
C16H11F3N2O2
  1
1
IC50 = 5300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552112
 Compound Info 
5,5-dimethyl-3-[3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
   Show/Hide
C12H11F3N2O2
  1
1
IC50 = 6000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552107
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethyl-1-methylsulfonylimidazolidine-2,4-dione
   Show/Hide
C13H12F4N2O4S
  1
1
IC50 = 6300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558331
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethyl-1,3-diazinane-2,4-dione
   Show/Hide
C13H12F4N2O2
  1
1
IC50 = 6900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0558460
 Compound Info 
1-[4-fluoro-3-(trifluoromethyl)phenyl]-4,4-dimethylimidazolidin-2-one
   Show/Hide
C12H12F4N2O
  1
1
IC50 = 8100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552111
 Compound Info 
5-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-fluoro-N,N-dimethylbenzamide
   Show/Hide
C14H16FN3O3
  1
1
IC50 = 9100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0470076
 Compound Info 
5,5-dimethyl-3-pyridin-3-ylimidazolidine-2,4-dione
   Show/Hide
C10H11N3O2
  1
1
IC50 = 9600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0243413
 Compound Info 
5,5-dimethyl-3-pyrazin-2-ylimidazolidine-2,4-dione
   Show/Hide
C9H10N4O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0317457
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-6,6-dimethyl-1,3-diazinane-2,4-dione
   Show/Hide
C13H12F4N2O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0317459
 Compound Info 
5,5-dimethyl-3-[4-methyl-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
   Show/Hide
C13H13F3N2O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0353983
 Compound Info 
3-[3-(difluoromethyl)-4-fluorophenyl]-5-methylimidazolidine-2,4-dione
   Show/Hide
C11H9F3N2O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0470075
 Compound Info 
5,5-dimethyl-3-[6-(trifluoromethyl)pyridin-3-yl]imidazolidine-2,4-dione
   Show/Hide
C11H10F3N3O2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565133
 Compound Info 
3-[4-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethylpyrrolidine-2,4-dione
   Show/Hide
C13H11F4NO2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0958007
 Compound Info 
3-[3-(Difluoromethyl)-4-fluorophenyl]-5,5-dimethylimidazolidine-2,4-dione
   Show/Hide
C12H11F3N2O2
  1
1
IC50 >= 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Lymph node)
Cell Line Name Organism Disease
AN3-CA
 Cell Line Info 
Homo sapiens (Human) Acanthosis nigricans--NCIt; C7359; Endometrial adenocarcinoma
A2058
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
LOX-IMVI
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
SW620
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SW620/AD300
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
LoVo
 Cell Line Info 
Homo sapiens (Human) Colon adenocarcinoma
SK-MEL-5
 Cell Line Info 
Homo sapiens (Human) Cutaneous melanoma
SU-DHL-5
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma germinal center B-cell type
HOC313
 Cell Line Info 
Homo sapiens (Human) Floor of mouth squamous cell carcinoma
HGC-27
 Cell Line Info 
Homo sapiens (Human) Gastric carcinoma
NUGC-4
 Cell Line Info 
Homo sapiens (Human) Gastric signet ring cell adenocarcinoma
NCI-H1993
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC-9
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H838
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1568
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
PC9-DRH
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H2009
 Cell Line Info 
Homo sapiens (Human) Lung adenocarcinoma
NCI-H1299
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H1155
 Cell Line Info 
Homo sapiens (Human) Lung large cell carcinoma
NCI-H292
 Cell Line Info 
Homo sapiens (Human) Lung mucoepidermoid carcinoma
HBL-2 [Human mantle cell lymphoma]
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
MNT-1
 Cell Line Info 
Homo sapiens (Human) Melanoma
JR8
 Cell Line Info 
Homo sapiens (Human) Melanoma
MM96L
 Cell Line Info 
Homo sapiens (Human) Melanoma
WM3629
 Cell Line Info 
Homo sapiens (Human) Melanoma
L3.6pl
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenosquamous carcinoma
LNCaP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-AR
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP C4-2
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
MR49F
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCaP-hr
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
LNCap-ARR2PB-eGFP
 Cell Line Info 
Homo sapiens (Human) Prostate carcinoma
Th17
 Cell Line Info 
Mus musculus (Mouse) -