| Compound ID |
Compound Name |
Compound Formula |
|
CP0437560
|
(E)-3-[6-(3-chloro-4-pyridin-2-ylphenoxy)pyridin-3-yl]-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]prop-2-enamide
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C38H35ClN4O4
|
2
|
| 1 |
EC50 = 37.2 nM
|
|
|
| 2 |
IC50 = 560 nM
|
|
|
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CP0391451
|
(E)-3-[6-(3-cyano-4-pyridin-2-ylphenoxy)pyridin-3-yl]-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]prop-2-enamide
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|
C39H35N5O4
|
2
|
| 1 |
EC50 = 51 nM
|
|
|
| 2 |
IC50 = 610 nM
|
|
|
|
CP0437791
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(4-pyridin-3-ylphenoxy)pyridin-3-yl]prop-2-enamide
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|
C38H36N4O4
|
2
|
| 1 |
EC50 = 103.4 nM
|
|
|
| 2 |
IC50 = 390 nM
|
|
|
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CP0577510
|
(3R,11S,11aS)-2-acetyl-3-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinolin-6-one
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|
C29H26N2O6
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0575134
|
(8S,10aS,11R)-9-acetyl-8-benzyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-8,10,10a,11-tetrahydro-7H-pyrazino[1,2-g][1,6]naphthyridin-5-one
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|
C28H27N3O5
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0489344
|
(5S,5aS,8S)-7-acetyl-8-benzoyl-5-(7-methoxy-1,3-benzodioxol-5-yl)-5a,6,8,9-tetrahydro-5H-pyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C28H25N3O6
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0571947
|
(8R,10aS,11R)-9-acetyl-8-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-8,10,10a,11-tetrahydro-7H-pyrazino[1,2-g][1,6]naphthyridin-5-one
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|
C28H25N3O6
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0575297
|
(5S,5aS,8R)-7-acetyl-8-benzoyl-5-(7-methoxy-1,3-benzodioxol-5-yl)-5a,6,8,9-tetrahydro-5H-pyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C28H25N3O6
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0534311
|
(3S,11S,11aS)-2-acetyl-3-benzyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b][2,7]naphthyridin-6-one
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|
C28H27N3O5
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0571895
|
(3S,11S,11aS)-2-acetyl-3-benzyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinolin-6-one
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|
C29H28N2O5
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0535459
|
(5S,5aS)-7-acetyl-5-(7-methoxy-1,3-benzodioxol-5-yl)-5a,6-dihydro-5H-pyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C21H19N3O5
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0539724
|
1-[(2R,3S,6S,10R,11S)-13-methoxy-6-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-5-yl]ethanone
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|
C33H34N2O7
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0542871
|
(2R,3S,6S,10R,11S)-5-acetyl-13-methoxy-6-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-9-one
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|
C33H32N2O8
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0574392
|
(5S,5aS,8S)-7-acetyl-8-benzyl-5-(7-methoxy-1,3-benzodioxol-5-yl)-5a,6,8,9-tetrahydro-5H-pyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C28H27N3O5
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0420976
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(3-methyl-4-pyridin-2-ylphenoxy)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C39H38N4O4
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0574393
|
(5S,5aS,8S)-5-(7-methoxy-1,3-benzodioxol-5-yl)-8-(1-phenylethenyl)-5,5a,6,7,8,9-hexahydropyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C27H25N3O4
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0521003
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-2-(1-methyl-2-phenylindol-3-yl)-2-morpholin-4-ylacetamide
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|
C40H44N4O4
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0524626
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-(3-methyl-5-pyridin-2-yl-2-pyridin-2-yloxyphenyl)prop-2-enamide
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|
C39H38N4O4
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0571945
|
(5S,5aS,8S)-8-benzoyl-5-(7-methoxy-1,3-benzodioxol-5-yl)-5,5a,6,7,8,9-hexahydropyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C26H23N3O5
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0574391
|
(5S,5aS,8R)-8-benzoyl-5-(7-methoxy-1,3-benzodioxol-5-yl)-5,5a,6,7,8,9-hexahydropyrazino[2,1-g][1,7]naphthyridin-11-one
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|
C26H23N3O5
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0570872
|
(10aS,11R)-9-acetyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-10a,11-dihydro-10H-pyrazino[1,2-g][1,6]naphthyridin-5-one
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|
C21H19N3O5
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0036382
|
CAS_52-53-9
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|
C27H38N2O4
|
5
|
| 1 |
IC50 = 630 nM
|
|
|
| 2 |
IC50 = 710 nM
|
|
|
| 3 |
IC50 = 810 nM
|
|
|
| 4 |
IC50 = 2980 nM
|
|
|
| 5 |
IC50 > 30000 nM
|
|
|
|
CP0437559
|
(E)-3-[6-(2-bromo-4-pyridin-2-ylphenoxy)pyridin-3-yl]-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]prop-2-enamide
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|
C38H35BrN4O4
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0417462
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(2-methyl-4-pyridin-2-ylphenoxy)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C39H38N4O4
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0473128
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(3-pyridin-2-ylphenoxy)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C38H36N4O4
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0417463
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(2-iodo-4-pyridin-2-ylphenoxy)pyridin-3-yl]prop-2-enamide
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|
C38H35IN4O4
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0420977
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-2-[6-(4-pyridin-2-ylphenoxy)pyridin-3-yl]cyclopropane-1-carboxamide
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|
C39H38N4O4
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0542875
|
(2R,3S,6S,10R,11S)-13-methoxy-6-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-triene
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|
C31H32N2O6
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0543935
|
(3R,11S,11aS)-3-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b][2,6]naphthyridin-6-one
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|
C26H23N3O5
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0571896
|
(3S,11S,11aS)-3-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b][2,6]naphthyridin-6-one
Show/Hide
|
C26H23N3O5
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0520980
|
(E)-3-[6-(3,5-dihydroxy-4-pyridin-2-ylphenoxy)pyridin-3-yl]-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]prop-2-enamide
Show/Hide
|
C38H36N4O6
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0577025
|
(11S,11aS)-2-acetyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-11,11a-dihydro-1H-pyrazino[1,2-b]isoquinolin-6-one
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|
C22H20N2O5
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0416401
|
(2R,3S,6S,10S,11S)-5-acetyl-6-benzyl-10-hydroxy-13-methoxy-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-9-one
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|
C31H30N2O6
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
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CP0437790
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-enamide
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|
C36H36N4O3
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0521337
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(3-hydroxy-4-pyridin-2-ylphenoxy)pyridin-3-yl]prop-2-enamide
Show/Hide
|
C38H36N4O5
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0576785
|
(11S,11aS)-2-acetyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-11,11a-dihydro-1H-pyrazino[1,2-b][2,7]naphthyridin-6-one
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|
C21H19N3O5
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
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CP0396931
|
1-[(2R,3S,6S,10S,11S)-10-hydroxy-13-methoxy-6-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-5-yl]ethanone
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|
C33H34N2O8
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0496307
|
(2R,3S,6S,10S,11S)-5-acetyl-10-hydroxy-13-methoxy-6-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-9-one
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|
C33H32N2O9
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0535457
|
(3R,11S,11aS)-2-acetyl-3-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b][2,6]naphthyridin-6-one
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|
C28H25N3O6
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0575135
|
(3S,11S,11aS)-2-acetyl-3-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b][2,6]naphthyridin-6-one
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|
C28H25N3O6
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0542874
|
(3R,11S,11aS)-3-benzoyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b]isoquinolin-6-one
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|
C27H24N2O5
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0574394
|
(3S,11S,11aS)-11-(7-methoxy-1,3-benzodioxol-5-yl)-3-(1-phenylethenyl)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b][2,6]naphthyridin-6-one
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|
C27H25N3O4
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0460826
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-[6-(4-pyridin-2-ylphenoxy)pyridin-2-yl]prop-2-enamide
Show/Hide
|
C38H36N4O4
|
1
|
| 1 |
IC50 = 990 nM
|
|
|
|
CP0489345
|
(3S,11S,11aS)-2-acetyl-3-benzyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b][2,6]naphthyridin-6-one
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|
C28H27N3O5
|
1
|
| 1 |
IC50 = 1010 nM
|
|
|
|
CP0544225
|
2-[(3S,14S)-12-hydroxy-3-[(1R)-1-hydroxyethyl]-14-methyl-10-oxo-15-oxa-2-azapentacyclo[9.7.1.02,6.07,19.013,18]nonadeca-1(19),6,8,11,13(18),16-hexaen-16-yl]acetic acid
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|
C22H21NO6
|
1
|
| 1 |
IC50 = 1010 nM
|
|
|
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CP0496309
|
(11S,11aS)-2-acetyl-11-(7-methoxy-1,3-benzodioxol-5-yl)-11,11a-dihydro-1H-pyrazino[1,2-b][2,6]naphthyridin-6-one
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|
C21H19N3O5
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
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CP0528668
|
(2R,3S,6S,10R,11S)-6-benzyl-13-methoxy-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-9-one
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|
C29H28N2O4
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
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CP0572592
|
(3S,11S,11aS)-11-(7-methoxy-1,3-benzodioxol-5-yl)-3-(1-phenylethenyl)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b]isoquinolin-6-one
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|
C28H26N2O4
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
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CP0532246
|
(2R,3S,6S,10R,11S)-5-acetyl-6-benzyl-13-methoxy-11-phenyl-15,17-dioxa-5,8-diazapentacyclo[10.7.0.02,10.03,8.014,18]nonadeca-1(19),12,14(18)-trien-9-one
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|
C31H30N2O5
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
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CP0475228
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-2-hydroxy-2-(1-methyl-2-phenylindol-3-yl)acetamide
Show/Hide
|
C36H37N3O4
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
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CP0437558
|
(E)-3-[6-(2,6-diiodo-4-pyridin-2-ylphenoxy)pyridin-3-yl]-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]prop-2-enamide
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|
C38H34I2N4O4
|
1
|
| 1 |
IC50 = 1180 nM
|
|
|
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CP0564287
|
methyl 2-[(3S,14S,16R)-12-hydroxy-3-[(1R)-1-hydroxyethyl]-14-methyl-10-oxo-15-oxa-2-azapentacyclo[9.7.1.02,6.07,19.013,18]nonadeca-1(19),6,8,11,13(18)-pentaen-16-yl]acetate
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|
C23H25NO6
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
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CP0473127
|
(E)-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-3-(4-oxo-2-phenylchromen-3-yl)prop-2-enamide
Show/Hide
|
C37H34N2O5
|
1
|
| 1 |
IC50 = 1360 nM
|
|
|
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CP0564288
|
2-[(3S,14R)-12-hydroxy-3-[(1R)-1-hydroxyethyl]-14-methyl-10-oxo-15-oxa-2-azapentacyclo[9.7.1.02,6.07,19.013,18]nonadeca-1(19),6,8,11,13(18),16-hexaen-16-yl]acetic acid
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|
C22H21NO6
|
1
|
| 1 |
IC50 = 1440 nM
|
|
|
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CP0564289
|
2-[(3S,14S,16S)-12-hydroxy-3-[(1R)-1-hydroxyethyl]-14-methyl-10,17-dioxo-15-oxa-2-azapentacyclo[9.7.1.02,6.07,19.013,18]nonadeca-1(18),6,8,11(19),12-pentaen-16-yl]acetic acid
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|
C22H21NO7
|
1
|
| 1 |
IC50 = 1480 nM
|
|
|
|
CP0569641
|
2-[(3R,14R,16S)-12-hydroxy-3-[(1R)-1-hydroxyethyl]-14-methyl-10-oxo-15-oxa-2-azapentacyclo[9.7.1.02,6.07,19.013,18]nonadeca-1(19),6,8,11,13(18)-pentaen-16-yl]acetic acid
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|
C22H23NO6
|
1
|
| 1 |
IC50 = 1530 nM
|
|
|
|
CP0524407
|
N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-2-(7-methoxy-4-methyl-2-oxochromen-3-yl)acetamide
Show/Hide
|
C32H34N2O6
|
1
|
| 1 |
IC50 = 1970 nM
|
|
|
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CP0570871
|
1-[(2S,5S)-2-benzyl-5-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-4-(pyridine-2-carbonyl)piperazin-1-yl]ethanone
Show/Hide
|
C28H29N3O5
|
1
|
| 1 |
IC50 = 2770 nM
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CP0577511
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1-[(2S,5S)-4-benzoyl-2-benzyl-5-[(7-hydroxy-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl]ethanone
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C28H28N2O5
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1
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| 1 |
IC50 = 3130 nM
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CP0537745
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1-[(2S,5S)-2-benzyl-5-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-4-(pyridine-3-carbonyl)piperazin-1-yl]ethanone
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C28H29N3O5
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1
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| 1 |
IC50 = 3550 nM
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CP0571948
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(3S,7S,8aS)-2-acetyl-3-benzyl-3'-methoxyspiro[3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazine-7,5'-furan]-2',6-dione
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C20H22N2O5
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1
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| 1 |
IC50 = 4130 nM
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CP0575133
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1-[(2S,5S)-4-benzoyl-2-benzyl-5-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl]ethanone
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C29H30N2O5
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1
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| 1 |
IC50 = 4360 nM
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CP0564290
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(3R)-4-[(8S)-4,5-dihydroxy-8-[(1R)-1-hydroxyethyl]-3-oxo-9,10-dihydro-8H-pyrrolo[1,2-a]benzo[cd]indol-6-yl]-3-hydroxybutanoic acid
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C20H21NO7
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1
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| 1 |
IC50 = 4490 nM
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CP0496308
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1-[(2S,5S)-2-benzyl-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]piperazin-1-yl]ethanone
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C22H28N2O4
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1
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| 1 |
IC50 = 4500 nM
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CP0001940
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(8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione
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C27H29NO11
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2
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| 1 |
IC50 = 4900 nM
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| 2 |
IC50 = 5750 nM
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CP0568010
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2-[(3S,15R,17R)-12-hydroxy-3-[(1R)-1-hydroxyethyl]-15-methyl-10-oxo-14,16-dioxa-2-azapentacyclo[9.8.1.02,6.07,20.013,19]icosa-1(19),6,8,11(20),12-pentaen-17-yl]acetic acid
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C22H23NO7
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1
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| 1 |
IC50 = 5040 nM
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CP0542876
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1-[(2S,5S)-4-benzoyl-2-benzyl-5-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]piperazin-1-yl]ethanone
Show/Hide
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C29H32N2O5
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1
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| 1 |
IC50 = 5080 nM
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CP0543937
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(3S,11S,11aS)-2-acetyl-3-benzoyl-11-(4-hydroxy-3,5-dimethoxyphenyl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinolin-6-one
Show/Hide
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C29H28N2O6
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1
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| 1 |
IC50 = 5150 nM
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CP0537747
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(E)-1-[(2S,5S)-4-acetyl-2,5-dibenzylpiperazin-1-yl]-3-phenylprop-2-en-1-one
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C29H30N2O2
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1
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| 1 |
IC50 = 5970 nM
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CP0571943
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1-[(2S,5S)-4-benzoyl-2,5-bis[(7-methoxy-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl]ethanone
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C31H32N2O8
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1
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| 1 |
IC50 = 6100 nM
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CP0577027
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1-[(2S,5S)-2-benzyl-5-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-4-(pyridine-4-carbonyl)piperazin-1-yl]ethanone
Show/Hide
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C28H29N3O5
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1
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| 1 |
IC50 = 6180 nM
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CP0535458
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(E)-1-[(2S,5S)-4-acetyl-5-benzyl-2-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl]-3-phenylprop-2-en-1-one
Show/Hide
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C31H32N2O5
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1
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| 1 |
IC50 = 6440 nM
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CP0542877
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(3S,7E,8S,8aS)-2-acetyl-7-[(4-hydroxyphenyl)methylidene]-8-(7-methoxy-1,3-benzodioxol-5-yl)-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
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C33H32N2O9
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1
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| 1 |
IC50 = 6450 nM
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CP0574390
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(3S,7E,8S,8aS)-2-acetyl-3-benzyl-7-[(4-hydroxy-3-methoxyphenyl)methylidene]-8-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
Show/Hide
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C32H32N2O7
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1
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| 1 |
IC50 = 6850 nM
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CP0542872
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(3R,11S,11aS)-2-acetyl-3-benzoyl-11-(4-hydroxy-3,5-dimethoxyphenyl)-3,4,11,11a-tetrahydro-1H-pyrazino[1,2-b]isoquinolin-6-one
Show/Hide
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C29H28N2O6
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1
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| 1 |
IC50 = 7050 nM
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CP0571944
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1-[(2S,5S)-4-benzoyl-2,5-dibenzylpiperazin-1-yl]ethanone
Show/Hide
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C27H28N2O2
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1
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| 1 |
IC50 = 7130 nM
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CP0542873
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(3S,7E,8S,8aS)-2-acetyl-3-benzyl-7-[(4-hydroxyphenyl)methylidene]-8-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
Show/Hide
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C31H30N2O6
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1
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| 1 |
IC50 = 7280 nM
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CP0546148
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(3R,7R,9R,20R)-11-hydroxy-20-[(1R)-1-hydroxyethyl]-3,7,9-trimethyl-4,8-dioxa-21-azahexacyclo[10.9.1.02,10.03,7.016,22.017,21]docosa-1,10,12(22),14,16-pentaene-5,13-dione
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C24H25NO6
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1
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| 1 |
IC50 = 7580 nM
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CP0542878
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(3S,7E,8S,8aS)-2-acetyl-7-[(4-hydroxy-3-methoxyphenyl)methylidene]-8-(7-methoxy-1,3-benzodioxol-5-yl)-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
Show/Hide
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C34H34N2O10
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1
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| 1 |
IC50 = 7640 nM
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CP0570873
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(E)-1-[(2S,5S)-4-acetyl-2,5-bis[(7-methoxy-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl]-3-phenylprop-2-en-1-one
Show/Hide
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C33H34N2O8
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1
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| 1 |
IC50 = 7820 nM
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CP0574799
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(E)-1-[(2S,5S)-4-acetyl-2,5-bis[(7-methoxy-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one
Show/Hide
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C34H36N2O10
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1
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| 1 |
IC50 = 9070 nM
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CP0396933
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(3S,3'S,7R,8R,8aS)-2-acetyl-3-benzyl-8-(7-methoxy-1,3-benzodioxol-5-yl)-3'-phenylspiro[3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazine-7,2'-oxirane]-6-one
Show/Hide
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C31H30N2O6
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1
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| 1 |
IC50 > 30000 nM
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CP0489400
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(3S,7E,8S,8aS)-2-acetyl-3-benzyl-7-benzylidene-8-(7-methoxy-1,3-benzodioxol-5-yl)-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
Show/Hide
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C31H30N2O5
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1
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| 1 |
IC50 > 30000 nM
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CP0530790
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(3S,3'S,7R,8R,8aS)-2-acetyl-8-(7-methoxy-1,3-benzodioxol-5-yl)-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-3'-phenylspiro[3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazine-7,2'-oxirane]-6-one
Show/Hide
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C33H32N2O9
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1
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| 1 |
IC50 > 30000 nM
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CP0541597
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(3S,7E,8S,8aS)-2-acetyl-7-benzylidene-8-(7-methoxy-1,3-benzodioxol-5-yl)-3-[(7-methoxy-1,3-benzodioxol-5-yl)methyl]-3,4,8,8a-tetrahydro-1H-pyrrolo[1,2-a]pyrazin-6-one
Show/Hide
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C33H32N2O8
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1
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| 1 |
IC50 > 30000 nM
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