Brief Information of the Cell Line and Protein
Cell Line ID: CL000104 , SW620
 Cell Line Info 
Synonyms
SW-620
SW 620
SW.620
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0547
Protein ID: PT05574 , Palmitoleoyl-protein carboxylesterase NOTUM
 Protein Info 
Gene Name NOTUM
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q6P988
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000104
 Cell Line Info 
 Protein ID: PT05574
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0408413
 Compound Info 
[7-[(4-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 2,3-dihydro-1,4-benzoxazine-4-carboxylate
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C22H21ClN4O5
  2
1
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 89 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0493755
 Compound Info 
[7-[(2-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 4-(4-methoxyphenyl)piperazine-1-carboxylate
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C25H28ClN5O5
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0529071
 Compound Info 
[7-[(4-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 4-(4-methoxyphenyl)piperazine-1-carboxylate
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C25H28ClN5O5
  1
1
IC50 = 290 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0408414
 Compound Info 
[7-(4-chlorobenzoyl)-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 2,3-dihydro-1,4-benzoxazine-4-carboxylate
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C22H19ClN4O6
  2
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 > 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0547962
 Compound Info 
[7-[(3-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 4-(4-methoxyphenyl)piperazine-1-carboxylate
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C25H28ClN5O5
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS