Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[7-[(4-chlorophenyl)methyl]-1,3-dioxo-5,6,8,8a-tetrahydroimidazo[1,5-a]pyrazin-2-yl] 2,3-dihydro-1,4-benzoxazine-4-carboxylate
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 PubChem ID
CID: 134817170
Canonical SMILES
Clc1ccc(CN2CCN3C(C2)C(=O)N(OC(=O)N2CCOc4ccccc24)C3=O)cc1
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Compound Formula C22H21ClN4O5
Compound Structure
Protein Name
 Protein Info 
Palmitoleoyl-protein carboxylesterase NOTUM
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q6P988
Gene Name
NOTUM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CL000104 SW620
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
IC50 = 89 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 170 nM