Brief Information of the Cell Line and Protein
Cell Line ID: CL000098 , A2058
Synonyms
A 2058
A-2058
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1059
Protein ID: PT01065 , Serine/threonine-protein kinase mTOR
Gene Name MTOR
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P42345
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000098  Protein ID: PT01065
 
Compound ID Compound Name Compound Formula
CP0013606
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
   Show/Hide
C17H20F3N7O2
 1
1
IC50 = 205 nM
   TI
   LI
   LO
   TS
CP0536937
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine
   Show/Hide
C16H19F3N8O2
 1
1
IC50 = 312 nM
   TI
   LI
   LO
   TS
CP0456424
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)pyridin-2-amine
   Show/Hide
C16H21N7O2
 1
1
IC50 = 415 nM
   TI
   LI
   LO
   TS
CP0563000
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)pyrimidin-2-amine
   Show/Hide
C15H20N8O2
 1
1
IC50 = 415 nM
   TI
   LI
   LO
   TS
CP0454795
N-[5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl]acetamide
   Show/Hide
C19H22F3N7O3
 1
1
IC50 = 729 nM
   TI
   LI
   LO
   TS
CP0574318
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)pyrazin-2-amine
   Show/Hide
C15H20N8O2
 1
1
IC50 = 817 nM
   TI
   LI
   LO
   TS
CP0476128
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-methylpyrimidin-2-amine
   Show/Hide
C16H22N8O2
 1
1
IC50 = 831 nM
   TI
   LI
   LO
   TS
CP0454797
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-methylpyridin-2-amine
   Show/Hide
C17H23N7O2
 1
1
IC50 = 939 nM
   TI
   LI
   LO
   TS
CP0508404
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-3-methylpyridin-2-amine
   Show/Hide
C17H23N7O2
 1
1
IC50 = 1105 nM
   TI
   LI
   LO
   TS
CP0394871
4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline
   Show/Hide
C17H22N6O2
 1
1
IC50 = 1282 nM
   TI
   LI
   LO
   TS
CP0454796
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-3-(trifluoromethyl)pyridin-2-amine
   Show/Hide
C17H20F3N7O2
 1
1
IC50 = 1638 nM
   TI
   LI
   LO
   TS
CP0567096
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-N-methoxy-4-(trifluoromethyl)pyridin-2-amine
   Show/Hide
C18H22F3N7O3
 1
1
IC50 = 5588 nM
   TI
   LI
   LO
   TS
CP0562999
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)-1H-pyridin-2-one
   Show/Hide
C17H19F3N6O3
 1
1
IC50 = 17000000 nM
   TI
   LI
   LO
   TS