General Information of the Compound
| Compound ID |
CP0013606
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| Compound Name |
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
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| Synonyms |
1225037-39-7
5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine
5-[bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)pyridin-2-amine
6Z3QHB00LB
ADGGYDAFIHSYFI-UHFFFAOYSA-N
BCP15887
Bimiralisib
Bimiralisib [INN]
Bimiralisib [USAN]
Bimiralisib [WHO-DD]
Bimiralisib free base
EX-A2018
GTPL8383
NCB5
PI3K-IN-2
PQR-309
PQR-309(PI3K-IN-2)
PQR309
SCHEMBL1309049
UNII-6Z3QHB00LB
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| Structure |
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| Formula |
C17H20F3N7O2
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| Molecular Weight |
411.388
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| Canonical SMILES |
Nc1cc(c(cn1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F
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| InChI |
InChI=1S/C17H20F3N7O2/c18-17(19,20)12-9-13(21)22-10-11(12)14-23-15(26-1-5-28-6-2-26)25-16(24-14)27-3-7-29-8-4-27/h9-10H,1-8H2,(H2,21,22)
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| InChIKey |
ADGGYDAFIHSYFI-UHFFFAOYSA-N
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| CAS |
1225037-39-7
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000098 | A2058 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 2333 nM
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Clinical Information about the Compound