Brief Information of the Compound and Protein
Compound Name
2-(4-ethylsulfonylphenyl)-N-[5-(2-methoxyphenoxy)-4-phenyl-1,3-thiazol-2-yl]acetamide
    Show/Hide
PubChem ID
CID: 122186248
Canonical SMILES
CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(Oc3ccccc3OC)s2)-c2ccccc2)cc1
    Show/Hide
Compound Formula C26H24N2O5S2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51450
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000792 Th17 Mus musculus (Mouse)  1
1
IC50 = 251.19 nM
   TI
   LI
   LO
   TS