Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(3-cyanophenyl)-5-[2-(trifluoromethyl)phenoxy]-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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 PubChem ID
CID: 60142998
SID: 143485968
Canonical SMILES
CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(Oc3ccccc3C(F)(F)F)s2)-c2cccc(c2)C#N)cc1
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Compound Formula C27H20F3N3O4S2
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51450
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000792 Th17
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 251.19 nM
   TI
   LI
   LO
   TS