Brief Information of the Compound and Protein
Compound Name
 Compound Info 
12-methyl-4-(methylsulfonylmethyl)-8-pyridin-2-yl-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaen-14-one
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 PubChem ID
CID: 145966522
Canonical SMILES
Cn1cc2CN(c3ccccn3)c3ccc(CS(C)(=O)=O)cc3-c3c[nH]c(=O)c1c23
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Compound Formula C22H20N4O3S
Compound Structure
Protein Name
 Protein Info 
Bromodomain-containing protein 4
Protein Classification
Epigenetic regulator
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Bromodomain
Uniprot ID
O60885
Gene Name
BRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000095 NCI-H1299
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.9 nM