Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2-(2,4-difluorophenoxy)-5-methylsulfonylphenyl]-7-methyl-2,6-dihydropyrrolo[3,4-d]pyridazin-1-one
    Show/Hide
 PubChem ID
CID: 136387545
Canonical SMILES
Cc1[nH]c(-c2cc(ccc2Oc2ccc(F)cc2F)S(C)(=O)=O)c2cn[nH]c(=O)c12
    Show/Hide
Compound Formula C20H15F2N3O4S
Compound Structure
Protein Name
 Protein Info 
Bromodomain-containing protein 4
Protein Classification
Epigenetic regulator
>
Reader
>
Bromodomain
Uniprot ID
O60885
Gene Name
BRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000095 NCI-H1299
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 750 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 77 nM