General Information of the Compound
Compound ID |
CP0069311
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Compound Name |
US10633379, Compound X
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Synonyms |
1445993-26-9
8NG
ABBV-075
ABBV-075 (Mivebresib)
ABBV075
AKOS030628486
BDBM220447
CHEMBL3987016
CS-5815
EX-A1082
GTPL9117
Mivebresib
Mivebresib [INN]
Mivebresib(ABBV-075 pound(c)
MolPort-044-561-801
N-(4-(2,4-difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide
N-[4-(2,4-Difluorophenoxy)-3-(6-Methyl-7-Oxo-6,7-Dihydro-1h-Pyrrolo[2,3-C]pyridin-4-Yl)phenyl]ethanesulfonamide
RDONXGFGWSSFMY-UHFFFAOYSA-N
SCHEMBL15068241
UNII-VR86R11J7J
VR86R11J7J
ZINC146486516
s8400
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Structure |
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Formula |
C22H19F2N3O4S
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Molecular Weight |
459.474
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Canonical SMILES |
CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)c2[nH]ccc12
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InChI |
InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3
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InChIKey |
RDONXGFGWSSFMY-UHFFFAOYSA-N
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CAS |
1445993-26-9
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Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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PubChem ID | |||||||||||||||||||
ChEMBL ID |
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01462, Bromodomain-containing protein 4
Cell Viability or Cytotoxicity Assay
Cell Line ID | Cell Line Name | Cell Line Organism | |
CL000183 | MX-1 | Homo sapiens (Human) | 1 |
1 |
EC50 = 13 nM
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Clinical Information about the Compound