| Compound ID |
Compound Name |
Compound Formula |
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
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|
C8H11NO2
|
5
|
| 1 |
EC50 = 0.69 nM
|
|
|
| 2 |
EC50 = 0.99 nM
|
|
|
| 3 |
EC50 = 6.7 nM
|
|
|
| 4 |
EC50 = 40 nM
|
|
|
| 5 |
EC50 = 140 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
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|
C13H21N3
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0546706
|
[4-(3-carbamoylphenyl)-3-methoxyphenyl] N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
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|
C30H36N4O5
|
1
|
| 1 |
EC50 = 10.4 nM
|
|
|
|
CP0042751
|
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
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|
C17H17NO2
|
3
|
| 1 |
EC50 = 12.7 nM
|
|
|
| 2 |
IC50 = 4.2 nM
|
|
|
| 3 |
Ki > 217 nM
|
|
|
|
CP0420406
|
[4-(3-carbamoylphenyl)phenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C28H30Cl2N4O3
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0437064
|
[3-(3-carbamoylphenyl)phenyl] N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
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|
C27H28Cl2N4O3
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0437063
|
[4-(3-carbamoylphenyl)-3-fluorophenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C28H29Cl2FN4O3
|
1
|
| 1 |
EC50 = 13.7 nM
|
|
|
|
CP0463995
|
(4-phenylphenyl) N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
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|
C26H27Cl2N3O2
|
1
|
| 1 |
EC50 = 14.7 nM
|
|
|
|
CP0437066
|
[4-(3-carbamoylphenyl)phenyl] N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]carbamate
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|
C28H32N4O4
|
1
|
| 1 |
EC50 = 21.5 nM
|
|
|
|
CP0392723
|
N-[4-[2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
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|
C21H30N6
|
2
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0373187
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
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|
C22H31N5
|
2
|
| 1 |
EC50 = 29 nM
|
|
|
| 2 |
Ki = 5.2 nM
|
|
|
|
CP0546704
|
[4-(3-carbamoylphenyl)phenyl] N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]carbamate
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|
C27H28Cl2N4O3
|
1
|
| 1 |
EC50 = 39.9 nM
|
|
|
|
CP0420412
|
[3-(3-carbamoylphenyl)phenyl] N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
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|
C28H30Cl2N4O3
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0546705
|
[4-(3-carbamoylphenyl)phenyl] N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]carbamate
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|
C29H34N4O3
|
1
|
| 1 |
EC50 = 49.3 nM
|
|
|
|
CP0384679
|
N-(3-methylphenyl)-3-(4-pyridin-2-ylpiperidin-1-yl)propanamide
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|
C20H25N3O
|
4
|
| 1 |
EC50 = 50.1 nM
|
|
|
| 2 |
EC50 = 2480 nM
|
|
|
| 3 |
IC50 = 7627 nM
|
|
|
| 4 |
IC50 > 100000 nM
|
|
|
|
CP0862246
|
[4-(3-Carbamoylphenyl)phenyl]N-[4-[4-(2-Methoxyphenyl)-piperazin-1-yl]butyl]carbamate Hydrochloride
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|
C29H35ClN4O4
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
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|
C28H30N4O4S
|
2
|
| 1 |
EC50 = 54 nM
|
|
|
| 2 |
Ki = 6.3 nM
|
|
|
|
CP0420413
|
[3-(3-carbamoylphenyl)phenyl] N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]carbamate
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|
C28H32N4O4
|
1
|
| 1 |
EC50 = 54.2 nM
|
|
|
|
CP0408056
|
[3-(3-carbamoylphenyl)phenyl] N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
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|
C29H34N4O4
|
1
|
| 1 |
EC50 = 56.4 nM
|
|
|
|
CP0464005
|
9H-carbazol-2-yl N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]carbamate
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|
C28H32N4O3
|
1
|
| 1 |
EC50 = 57.9 nM
|
|
|
|
CP0437065
|
[4-(3-carbamoylphenyl)-3-fluorophenyl] N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]carbamate
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|
C28H27Cl2FN4O3
|
1
|
| 1 |
EC50 = 66.2 nM
|
|
|
|
CP0434177
|
[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
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|
C21H24N4O3
|
1
|
| 1 |
EC50 = 128 nM
|
|
|
|
CP0711830
|
(4-Phenylphenyl)N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]carbamate Hydrochloride
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|
C27H30Cl3N3O2
|
1
|
| 1 |
EC50 = 135 nM
|
|
|
|
CP0412102
|
(6-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C21H24N4O2
|
1
|
| 1 |
EC50 = 138 nM
|
|
|
|
CP0408058
|
[4-(3-carbamoylphenyl)phenyl] N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]carbamate
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|
C28H28Cl2N4O3
|
1
|
| 1 |
EC50 = 147 nM
|
|
|
|
CP0384372
|
N-(3-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propanamide
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|
C19H24N4O
|
4
|
| 1 |
EC50 = 154 nM
|
|
|
| 2 |
EC50 = 1455 nM
|
|
|
| 3 |
IC50 = 7067 nM
|
|
|
| 4 |
IC50 > 100000 nM
|
|
|
|
CP0434180
|
(4-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C21H24N4O2
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0418423
|
(6-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 183 nM
|
|
|
|
CP0382956
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0439996
|
(4-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 217 nM
|
|
|
|
CP0001212
|
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
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|
C23H29N5OS
|
2
|
| 1 |
EC50 = 254 nM
|
|
|
| 2 |
IC50 = 328.3 nM
|
|
|
|
CP0472959
|
(6-methoxy-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 364 nM
|
|
|
|
CP0472954
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 413 nM
|
|
|
|
CP0421087
|
1H-indol-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
EC50 = 570 nM
|
|
|
|
CP0421085
|
1-benzothiophen-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
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|
C20H21N3O2S
|
2
|
| 1 |
EC50 = 617 nM
|
|
|
| 2 |
IC50 = 2100 nM
|
|
|
|
CP0437975
|
(7-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 617 nM
|
|
|
|
CP0412093
|
1H-benzimidazol-2-yl-[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
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|
C21H24N4O3
|
2
|
| 1 |
EC50 = 660 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
|
CP0873148
|
1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
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|
C20H27Cl3N2O
|
1
|
| 1 |
EC50 = 757 nM
|
|
|
|
CP0384672
|
N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
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|
C18H22N4O
|
4
|
| 1 |
EC50 = 763 nM
|
|
|
| 2 |
EC50 = 26175 nM
|
|
|
| 3 |
IC50 = 16010 nM
|
|
|
| 4 |
IC50 > 100000 nM
|
|
|
|
CP0382983
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0412156
|
(7-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 786 nM
|
|
|
|
CP0421088
|
[4-[2-(5-chloropyridin-3-yl)oxyethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 790 nM
|
|
|
|
CP0412249
|
(3-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
|
CP0434157
|
[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
2
|
| 1 |
EC50 = 830 nM
|
|
|
| 2 |
IC50 = 7400 nM
|
|
|
|
CP0418430
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(6-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0434161
|
(5-methyl-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0434182
|
(5-chloro-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0384370
|
N-(3-ethylphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C19H24N4O
|
4
|
| 1 |
EC50 = 1600 nM
|
|
|
| 2 |
EC50 = 3887 nM
|
|
|
| 3 |
IC50 = 40466 nM
|
|
|
| 4 |
IC50 = 88447 nM
|
|
|
|
CP0434144
|
1-benzofuran-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0434159
|
(5-methoxy-1H-indol-2-yl)-[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0412250
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0434162
|
1H-indol-2-yl-[4-(2-phenoxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H23N3O2
|
2
|
| 1 |
EC50 = 1800 nM
|
|
|
| 2 |
IC50 = 535 nM
|
|
|
|
CP0439997
|
[4-[2-(4-chlorophenoxy)propyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0384381
|
N-pyridin-3-yl-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
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|
C16H19N5O
|
3
|
| 1 |
EC50 = 1965 nM
|
|
|
| 2 |
EC50 = 48503 nM
|
|
|
| 3 |
IC50 > 100000 nM
|
|
|
|
CP0384667
|
N-(3-methylphenyl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C17H21N5O
|
4
|
| 1 |
EC50 = 2092 nM
|
|
|
| 2 |
EC50 = 8321 nM
|
|
|
| 3 |
IC50 = 25008 nM
|
|
|
| 4 |
IC50 > 100000 nM
|
|
|
|
CP0422654
|
(4-methoxyphenyl)-[4-(2-phenoxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H24N2O3
|
2
|
| 1 |
EC50 = 2300 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0491760
|
1H-indol-2-yl-[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
2
|
| 1 |
EC50 = 2300 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0412251
|
1H-benzimidazol-2-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 2400 nM
|
|
|
|
CP0418429
|
1H-indol-5-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
2
|
| 1 |
EC50 = 2500 nM
|
|
|
| 2 |
IC50 = 4600 nM
|
|
|
|
CP0434179
|
(5-methoxy-1H-indol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0472960
|
(4-methoxyphenyl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C19H23N3O3
|
2
|
| 1 |
EC50 = 2900 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0472979
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrolo[3,2-b]pyridin-2-yl)methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0412108
|
1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)propyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0472957
|
(6-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
2
|
| 1 |
EC50 = 3500 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0418431
|
1H-indazol-3-yl-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
EC50 = 4100 nM
|
|
|
|
CP0434156
|
[4-[2-(4-methoxyphenoxy)ethyl]-2-methylpiperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
2
|
| 1 |
EC50 = 4200 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0422664
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
2
|
| 1 |
EC50 = 4300 nM
|
|
|
| 2 |
IC50 = 744 nM
|
|
|
|
CP0434181
|
(1-methylindol-3-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 4400 nM
|
|
|
|
CP0472980
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(3-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
2
|
| 1 |
EC50 = 4400 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0472958
|
(4-methoxy-2-methylphenyl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H25N3O3
|
2
|
| 1 |
EC50 = 4600 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0382982
|
(6-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
1
|
| 1 |
EC50 = 5200 nM
|
|
|
|
CP0412090
|
(4-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
2
|
| 1 |
EC50 = 5200 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0470714
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[3,2-c]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
2
|
| 1 |
EC50 = 5500 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0556582
|
(7-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
2
|
| 1 |
EC50 = 6000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0463486
|
[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]-(1H-pyrrol-2-yl)methanone
Show/Hide
|
C16H20N4O2
|
2
|
| 1 |
EC50 = 6100 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0439995
|
(1-methylindol-2-yl)-[4-(2-pyridin-3-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
EC50 = 6200 nM
|
|
|
|
CP0412157
|
[4-[2-(1,3-benzodioxol-5-yloxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H23N3O4
|
2
|
| 1 |
EC50 = 7000 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0382958
|
(4-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
2
|
| 1 |
EC50 = 7100 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0402333
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[2,3-c]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
2
|
| 1 |
EC50 = 7800 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0434200
|
(5-methoxy-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O4
|
2
|
| 1 |
EC50 = 7800 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0432152
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 61.45 nM
|
|
|
|
CP0137322
|
1H-indol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0439994
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(7-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
2
|
| 1 |
EC50 = 10100 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0422656
|
(7-chloro-1H-indol-2-yl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24ClN3O3
|
2
|
| 1 |
EC50 = 13000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0418417
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(3-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 24000 nM
|
|
|
|
CP0418424
|
[4-[2-(4-fluorophenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C21H22FN3O2
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 = 9700 nM
|
|
|
|
CP0422652
|
1H-indol-2-yl-[4-[2-(4-methylphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O2
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0460935
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(5-methoxypyridin-2-yl)methanone
Show/Hide
|
C20H25N3O4
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0460936
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(5-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0382979
|
[4-[2-(3-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 = 6800 nM
|
|
|
|
CP0412252
|
1H-indol-2-yl-[4-[2-[4-(trifluoromethoxy)phenoxy]ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H22F3N3O3
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0418416
|
1H-indol-3-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O3
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 = 2800 nM
|
|
|
|
CP0463485
|
1-[2-(4-methoxyphenoxy)ethyl]-4-(4-methoxyphenyl)sulfonylpiperazine
Show/Hide
|
C20H26N2O5S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0472955
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-pyrrolo[3,2-b]pyridin-2-yl)methanone
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0066236
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0366351
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
10
|
| 1 |
IC50 = 0.16 nM
|
|
|
| 2 |
Kd = 0.4898 nM
|
|
|
| 3 |
Ki = 0.44 nM
|
|
|
| 4 |
Ki = 0.4677 nM
|
|
|
| 5 |
Ki = 1.4 nM
|
|
|
| 6 |
Ki = 1.6 nM
|
|
|
| 7 |
Ki = 1.862 nM
|
|
|
| 8 |
Ki = 3.25 nM
|
|
|
| 9 |
Ki = 4 nM
|
|
|
| 10 |
Ki > 217 nM
|
|
|
|
CP0046637
|
2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
Show/Hide
|
C21H26ClN3OS
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
3
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
Ki = 2.344 nM
|
|
|
|
CP0427995
|
Amisulpride
Show/Hide
|
C17H27N3O4S
|
1
|
| 1 |
IC50 = 3.04 nM
|
|
|
|
CP0386823
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0460840
|
(4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
|
C23H33N5O
|
2
|
| 1 |
IC50 = 9.9 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0867161
|
1-[3-(2,4-Dimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride
Show/Hide
|
C22H31ClN2O2
|
1
|
| 1 |
IC50 = 17.7 nM
|
|
|
|
CP0386828
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-6-chloroimidazo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C24H30ClF3N8O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0224658
|
8-chloro-7-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H26ClFN2O4
|
1
|
| 1 |
IC50 = 26.3 nM
|
|
|
|
CP0386822
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyrimidine-2-carboxamide
Show/Hide
|
C24H31F3N8O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0420786
|
9,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,3-diol
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0042262
|
N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
Show/Hide
|
C15H23N3O4S
|
2
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
Kd = 2.818 nM
|
|
|
|
CP0378578
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyrazine-2-carboxamide
Show/Hide
|
C24H31F3N8O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0386825
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C23H26F3N5O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0420788
|
10-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,3,9-triol
Show/Hide
|
C18H19NO4
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0873149
|
1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
IC50 = 78.5 nM
|
|
|
|
CP0404510
|
(4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
|
C22H30FN5
|
2
|
| 1 |
IC50 = 79 nM
|
|
|
| 2 |
Ki = 8.5 nM
|
|
|
|
CP0864251
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0410602
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C22H25Cl2N5O
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0386824
|
N-[4-(4-quinolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
IC50 = 161 nM
|
|
|
|
CP0420871
|
5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-19-ol
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0400253
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-3-[(dimethylamino)methyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C28H39F3N8O
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0379466
|
N-[4-(4-quinazolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
IC50 = 248 nM
|
|
|
|
CP0379465
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
1
|
| 1 |
IC50 = 261 nM
|
|
|
|
CP0379464
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-5-[(dimethylamino)methyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C28H39F3N8O
|
1
|
| 1 |
IC50 = 281 nM
|
|
|
|
CP0386830
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1H-benzimidazole-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
1
|
| 1 |
IC50 = 301 nM
|
|
|
|
CP0378576
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-3-[(dimethylamino)methyl]-1H-indole-2-carboxamide
Show/Hide
|
C29H40F3N7O
|
1
|
| 1 |
IC50 = 311 nM
|
|
|
|
CP0386826
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33F3N6O
|
1
|
| 1 |
IC50 = 418 nM
|
|
|
|
CP0419719
|
(17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-16-yl) acetate
Show/Hide
|
C21H21NO5
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0422653
|
1H-indol-2-yl-[4-[2-(1H-indol-5-yloxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0230384
|
(-)-Tetrahydropalmatine
Show/Hide
|
C21H25NO4
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0455841
|
5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-17-ol
Show/Hide
|
C18H17NO3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0472981
|
1H-indol-2-yl-[4-[3-(4-methoxyphenoxy)propyl]piperazin-1-yl]methanone
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
IC50 = 691 nM
|
|
|
|
CP0420785
|
17,19-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15,17,19-hexaen-18-ol
Show/Hide
|
C20H21NO5
|
1
|
| 1 |
IC50 = 1080 nM
|
|
|
|
CP0382984
|
1H-indol-2-yl-[4-[4-(4-methoxyphenoxy)butyl]piperazin-1-yl]methanone
Show/Hide
|
C24H29N3O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0427612
|
2,3-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-10-ol
Show/Hide
|
C19H21NO3
|
1
|
| 1 |
IC50 = 1530 nM
|
|
|
|
CP0003459
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H37N5OS
|
1
|
| 1 |
IC50 = 1616 nM
|
|
|
|
CP0046341
|
8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)
Show/Hide
|
C17H18ClNO
|
1
|
| 1 |
IC50 = 2050 nM
|
|
|
|
CP0424424
|
2,3,10-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-11-ol
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
IC50 = 2590 nM
|
|
|
|
CP0420870
|
2,3,10-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-9-ol
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
IC50 = 3110 nM
|
|
|
|
CP0455842
|
3,10,11-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
IC50 = 3580 nM
|
|
|
|
CP0463489
|
[4-[2-(4-chloro-3-methylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0424422
|
17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15,17,19-hexaen-18-ol
Show/Hide
|
C19H19NO4
|
1
|
| 1 |
IC50 = 4940 nM
|
|
|
|
CP0412091
|
1-benzothiophen-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0384374
|
2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)-N-(m-tolyl)acetamide
Show/Hide
|
C19H23N3O
|
2
|
| 1 |
IC50 = 5846 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0382981
|
(4-ethylphenyl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0438684
|
2,3,10,12-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-11-ol
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C21H25NO5
|
1
|
| 1 |
IC50 = 6360 nM
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CP0384369
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2-(4-phenylpiperidin-1-yl)-N-(m-tolyl)acetamide
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C20H24N2O
|
2
|
| 1 |
IC50 = 7692 nM
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| 2 |
IC50 = 16447 nM
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CP0412155
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1-benzofuran-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
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C22H24N2O4
|
1
|
| 1 |
IC50 = 7700 nM
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CP0427611
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(17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-16-yl) (E)-3-(4-acetyloxy-3-methoxyphenyl)prop-2-enoate
Show/Hide
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C31H29NO8
|
1
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| 1 |
IC50 = 7960 nM
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CP0559803
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2,3,11,12-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-10-ol
Show/Hide
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C21H25NO5
|
1
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| 1 |
IC50 = 8810 nM
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CP0434155
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[4-[2-(2-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
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C21H26N2O4
|
1
|
| 1 |
IC50 = 9000 nM
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CP0434172
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(4-chlorophenyl)-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
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C20H23ClN2O3
|
1
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| 1 |
IC50 = 9000 nM
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CP0412099
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[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1-methylindol-2-yl)methanone
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C23H27N3O3
|
1
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| 1 |
IC50 = 9600 nM
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CP0377202
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N-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
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C22H25N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0377208
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N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
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C21H23N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0398637
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-1-sulfonamide
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C24H29N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0398640
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
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C24H29N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0416325
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N-ethyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
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C23H27N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0416326
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N-(cyclopropylmethyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
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C25H29N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0417851
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N-benzyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
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C28H29N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0417858
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzenesulfonamide
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C20H27N3O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0487098
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propylnaphthalene-2-sulfonamide
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C24H29N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0424421
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(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(1R)-17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-16-yl]oxy]oxane-3,4,5-triol
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C25H29NO9
|
1
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| 1 |
IC50 > 10000 nM
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CP0427613
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19-phenylmethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaene
Show/Hide
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C25H23NO3
|
1
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| 1 |
IC50 > 10000 nM
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CP0440860
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(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(1S)-17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-16-yl]oxy]oxane-3,4,5-triol
Show/Hide
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C25H29NO9
|
1
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| 1 |
IC50 > 10000 nM
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CP0415799
|
[4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
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C20H23ClN2O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0422660
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[4-[2-(1,3-benzodioxol-5-yloxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
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C21H24N2O5
|
1
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| 1 |
IC50 > 10000 nM
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CP0443819
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[4-[2-(2-chloro-4-methoxyphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
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C22H24ClN3O3
|
1
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| 1 |
IC50 > 10000 nM
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CP0384371
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N-(3-methylphenyl)-3-(4-pyrimidin-2-ylpiperazin-1-yl)propanamide
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C18H23N5O
|
2
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| 1 |
IC50 = 11847 nM
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| 2 |
IC50 > 100000 nM
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CP0463488
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[4-[2-(3,4-dimethylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
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C23H27N3O2
|
1
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| 1 |
IC50 = 13000 nM
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CP0382963
|
MLS001173843
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C21H26N2O4
|
1
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| 1 |
IC50 = 15700 nM
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CP0384677
|
N-(3-ethylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide
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C20H25N3O
|
2
|
| 1 |
IC50 = 16278 nM
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| 2 |
IC50 = 67613 nM
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CP0434173
|
[4-[2-(4-methoxyphenoxy)propyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
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C22H28N2O4
|
1
|
| 1 |
IC50 = 18000 nM
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CP0434175
|
4-methoxy-N-[2-[2-(4-methoxyphenoxy)ethyl-methylamino]ethyl]-N-methylbenzamide
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C21H28N2O4
|
1
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| 1 |
IC50 = 18000 nM
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CP0384675
|
N-(3-methylphenyl)-2-[4-(4-methylphenyl)piperidin-1-yl]acetamide
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C21H26N2O
|
2
|
| 1 |
IC50 = 44834 nM
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| 2 |
IC50 = 89153 nM
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CP0384367
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-(3-ethylphenyl)acetamide
Show/Hide
|
C19H23ClN4O
|
2
|
| 1 |
IC50 = 46795 nM
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| 2 |
IC50 = 70703 nM
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CP0382957
|
[4-[2-(4-ethylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
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C23H27N3O2
|
1
|
| 1 |
IC50 > 50000 nM
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CP0382985
|
[4-[2-(4-ethylphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O3
|
1
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| 1 |
IC50 > 50000 nM
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CP0412092
|
1-[2-(4-methoxyphenoxy)ethyl]-4-(4-methoxyphenyl)piperazine
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C20H26N2O3
|
1
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| 1 |
IC50 > 50000 nM
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CP0412154
|
1H-benzimidazol-2-yl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C21H24N4O3
|
1
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| 1 |
IC50 > 50000 nM
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CP0412158
|
[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-phenylmethanone
Show/Hide
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C20H24N2O3
|
1
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| 1 |
IC50 > 50000 nM
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CP0418422
|
cyclohexyl-[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C20H30N2O3
|
1
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| 1 |
IC50 > 50000 nM
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CP0421086
|
[4-[2-(4-chlorophenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
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C21H22ClN3O2
|
1
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| 1 |
IC50 > 50000 nM
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CP0434169
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(4-methoxyphenyl)-[4-[2-[4-(trifluoromethoxy)phenoxy]ethyl]piperazin-1-yl]methanone
Show/Hide
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C21H23F3N2O4
|
1
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| 1 |
IC50 > 50000 nM
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CP0434170
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[4-[2-(3,5-dimethoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O5
|
1
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| 1 |
IC50 > 50000 nM
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CP0463487
|
[4-[2-(3,4-dimethoxyphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O4
|
1
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| 1 |
IC50 > 50000 nM
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CP0416633
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-(3-methylphenyl)acetamide
Show/Hide
|
C18H21ClN4O
|
2
|
| 1 |
IC50 = 66077 nM
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| 2 |
IC50 > 100000 nM
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CP0384375
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N-(3-methylphenyl)-2-(4-naphthalen-1-ylpiperazin-1-yl)acetamide
Show/Hide
|
C23H25N3O
|
2
|
| 1 |
IC50 = 68329 nM
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| 2 |
IC50 > 100000 nM
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CP0384376
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N-(3-methylphenyl)-2-[4-(5-methylpyridin-2-yl)piperidin-1-yl]acetamide
Show/Hide
|
C20H25N3O
|
2
|
| 1 |
IC50 = 71065 nM
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| 2 |
IC50 > 100000 nM
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CP0384366
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2-[4-(4-chlorophenyl)piperidin-1-yl]-N-(3-methylphenyl)acetamide
Show/Hide
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C20H23ClN2O
|
2
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| 1 |
IC50 = 71437 nM
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| 2 |
IC50 > 100000 nM
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CP0384678
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2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-pyrimidin-5-ylacetamide
Show/Hide
|
C15H17ClN6O
|
1
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| 1 |
IC50 = 72516 nM
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CP0421988
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-pyridin-3-ylacetamide
Show/Hide
|
C16H18ClN5O
|
1
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| 1 |
IC50 = 86617 nM
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CP0384383
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2-(4-pyridin-2-ylpiperazin-1-yl)-N-pyrimidin-5-ylacetamide
Show/Hide
|
C15H18N6O
|
1
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| 1 |
IC50 = 94255 nM
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CP0382960
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[4-[1-(4-methoxyphenoxy)propan-2-yl]piperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
1
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| 1 |
IC50 > 100000 nM
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CP0382961
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[4-[2-(4-ethoxyphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C23H27N3O3
|
1
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| 1 |
IC50 > 100000 nM
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CP0418425
|
[4-[2-(4-bromophenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C21H22BrN3O2
|
1
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| 1 |
IC50 > 100000 nM
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CP0421090
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1H-indol-2-yl-[4-[2-(4-methoxy-N-methylanilino)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C23H28N4O2
|
1
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| 1 |
IC50 > 100000 nM
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CP0434135
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[4-[2-(4-tert-butylphenoxy)ethyl]piperazin-1-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C25H31N3O2
|
1
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| 1 |
IC50 > 100000 nM
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CP0434164
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1H-indol-2-yl-[4-[2-(4-methylsulfanylphenoxy)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O2S
|
1
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| 1 |
IC50 > 100000 nM
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CP0434171
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[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(2-methoxyphenyl)methanone
Show/Hide
|
C21H26N2O4
|
1
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| 1 |
IC50 > 100000 nM
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CP0437980
|
1H-indol-2-yl-[4-(2-pyridin-2-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H22N4O2
|
1
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| 1 |
IC50 > 100000 nM
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CP0472956
|
1H-indol-2-yl-[4-(2-pyridin-4-yloxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C20H22N4O2
|
1
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| 1 |
IC50 > 100000 nM
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CP0491764
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1H-indol-2-yl-[4-[2-(4-methoxyphenyl)sulfanylethyl]piperazin-1-yl]methanone
Show/Hide
|
C22H25N3O2S
|
1
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| 1 |
IC50 > 100000 nM
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CP0491767
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[4-[2-(4-methoxyphenoxy)ethyl]-3-methylpiperazin-1-yl]-(4-methoxyphenyl)methanone
Show/Hide
|
C22H28N2O4
|
1
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| 1 |
IC50 > 100000 nM
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CP0386829
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
|
C30H42F3N5O
|
1
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| 1 |
IC50 > 500 nM
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CP0380100
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2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)-N,N-dimethylethanamine
Show/Hide
|
C17H18FN3O2S
|
1
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| 1 |
IC50 < 5000 nM
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CP0405688
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2-[3-(3-chlorophenyl)sulfonylpyrrolo[2,3-b]pyridin-1-yl]-N,N-dimethylethanamine
Show/Hide
|
C17H18ClN3O2S
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1
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| 1 |
IC50 < 5000 nM
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CP0419036
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N,N-dimethyl-2-(3-naphthalen-1-ylsulfonylpyrrolo[2,3-b]pyridin-1-yl)ethanamine
Show/Hide
|
C21H21N3O2S
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1
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| 1 |
IC50 < 5000 nM
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CP0424416
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2-[3-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl]ethylamine
Show/Hide
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C15H15N3O2S
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1
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| 1 |
IC50 < 5000 nM
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CP0439248
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2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}ethylamine
Show/Hide
|
C15H14ClN3O2S
|
1
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| 1 |
IC50 < 5000 nM
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CP0422595
|
4-[(1R,5S)-3-(4-chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C23H25ClFNO2
|
2
|
| 1 |
Kd = 0.05495 nM
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| 2 |
Ki = 0.05248 nM
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CP0418382
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4-[4-(3,4-dichlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C21H22Cl2FNO2
|
2
|
| 1 |
Kd = 0.1445 nM
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| 2 |
Ki = 0.1549 nM
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CP0422617
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4-[6-(4-chlorophenyl)-3-azabicyclo[4.1.0]heptan-3-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C22H23ClFNO
|
2
|
| 1 |
Kd = 0.1445 nM
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| 2 |
Ki = 0.1585 nM
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CP0434039
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4-[4-(2,3-dichlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C21H22Cl2FNO2
|
2
|
| 1 |
Kd = 0.1445 nM
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| 2 |
Ki = 0.1202 nM
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CP0418385
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1-(4-fluorophenyl)-4-[4-hydroxy-4-[4-(trifluoromethyl)phenyl]piperidin-1-yl]butan-1-one
Show/Hide
|
C22H23F4NO2
|
2
|
| 1 |
Kd = 0.4571 nM
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| 2 |
Ki = 0.3236 nM
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CP0422606
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4-[4-(3,5-dichlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C21H22Cl2FNO2
|
2
|
| 1 |
Kd = 0.537 nM
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| 2 |
Ki = 0.4467 nM
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CP0086592
|
4-(4-chlorophenyl)-1-[3-(4-fluorophenoxy)propyl]piperidin-4-ol
Show/Hide
|
C20H23ClFNO2
|
2
|
| 1 |
Kd = 0.7943 nM
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| 2 |
Ki = 1.072 nM
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CP0418378
|
CAS_1050-79-9
Show/Hide
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C22H26FNO2
|
2
|
| 1 |
Kd = 0.955 nM
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| 2 |
Ki = 0.7244 nM
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CP0418403
|
4-[4-(3-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C21H23ClFNO2
|
2
|
| 1 |
Kd = 1 nM
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| 2 |
Ki = 1 nM
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CP0421006
|
4-[4-(2,5-dichlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
|
C21H22Cl2FNO2
|
2
|
| 1 |
Kd = 1.047 nM
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| 2 |
Ki = 1.023 nM
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CP0418384
|
4-(4-chlorophenyl)-1-[2-[(1R,2S)-2-(4-fluorophenyl)cyclopropyl]ethyl]piperidin-4-ol
Show/Hide
|
C22H25ClFNO
|
2
|
| 1 |
Kd = 1.514 nM
|
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| 2 |
Ki = 1.514 nM
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CP0421011
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-phenyl-butan-1-one
Show/Hide
|
C21H24ClNO2
|
2
|
| 1 |
Kd = 1.778 nM
|
|
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| 2 |
Ki = 1.778 nM
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CP0437870
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4-[4-(4-chlorophenyl)-4-methoxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C22H25ClFNO2
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2
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| 1 |
Kd = 1.862 nM
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| 2 |
Ki = 1.905 nM
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CP0130353
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4-[4-(4-chlorophenyl)piperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C22H25N3O3S3
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2
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| 1 |
Kd = 1.905 nM
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| 2 |
Ki = 1.738 nM
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CP0074434
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4-(4-chlorophenyl)-1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-ol
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C20H23ClFNOS
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2
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| 1 |
Kd = 1.95 nM
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| 2 |
Ki = 2.089 nM
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CP0459706
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2-methylphenyl)butan-1-one
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C22H26ClNO2
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2
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| 1 |
Kd = 1.95 nM
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| 2 |
Ki = 3.548 nM
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CP0422612
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4-[4-(2,6-dichlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C21H22Cl2FNO2
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2
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| 1 |
Kd = 2.089 nM
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| 2 |
Ki = 1.479 nM
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CP0422618
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4-[4-(2,4-dichlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C21H22Cl2FNO2
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2
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| 1 |
Kd = 2.399 nM
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| 2 |
Ki = 2.63 nM
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CP0440040
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4-[4-[2-(2-chlorophenyl)phenyl]-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C27H27ClFNO2
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2
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| 1 |
Kd = 2.692 nM
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| 2 |
Ki = 2.455 nM
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CP0418380
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1-(4-fluorophenyl)-4-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]butan-1-one
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C21H23F2NO2
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2
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| 1 |
Kd = 3.02 nM
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| 2 |
Ki = 3.311 nM
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CP0418404
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4-[4-(2-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C21H23ClFNO2
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2
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| 1 |
Kd = 3.236 nM
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| 2 |
Ki = 2.138 nM
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CP0418399
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1-(2-chlorophenyl)-4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]butan-1-one
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C21H23Cl2NO2
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2
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| 1 |
Kd = 3.388 nM
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| 2 |
Ki = 3.548 nM
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CP0868218
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SID50106905
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C21H28ClNO
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1
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| 1 |
Kd = 4.32 nM
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CP0051336
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1-(4-Chloro-phenyl)-4-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-butan-1-one
Show/Hide
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C21H23Cl2NO2
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2
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| 1 |
Kd = 5.012 nM
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| 2 |
Ki = 5.012 nM
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CP0089174
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4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)butyl]piperidin-4-ol
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C21H25ClFNO
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2
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| 1 |
Kd = 6.761 nM
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| 2 |
Ki = 5.37 nM
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CP0468008
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(3,4-difluorophenyl)butan-1-one
Show/Hide
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C21H22ClF2NO2
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2
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| 1 |
Kd = 7.413 nM
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| 2 |
Ki = 7.762 nM
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CP0468011
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4-[4-[4-(dimethylamino)phenyl]-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C23H29FN2O2
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2
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| 1 |
Kd = 7.586 nM
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| 2 |
Ki = 5.248 nM
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CP0479779
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1-(4-Fluoro-phenyl)-4-(4-phenyl-piperidin-1-yl)-butan-1-one
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C21H24FNO
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2
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| 1 |
Kd = 7.943 nM
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| 2 |
Ki = 7.762 nM
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CP0459705
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1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butan-1-one
Show/Hide
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C21H24FNO2
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2
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| 1 |
Kd = 8.511 nM
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| 2 |
Ki = 7.586 nM
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CP0422594
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4-[4-(4-chlorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-1-(4-fluorophenyl)butan-1-one
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C21H21ClFNO
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2
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| 1 |
Kd = 10 nM
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| 2 |
Ki = 10 nM
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CP0418381
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2-fluorophenyl)butan-1-one
Show/Hide
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C21H23ClFNO2
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2
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| 1 |
Kd = 10.23 nM
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| 2 |
Ki = 7.943 nM
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CP0418383
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4-(4-chlorophenyl)-1-[(E)-4-(4-fluorophenyl)but-3-enyl]piperidin-4-ol
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C21H23ClFNO
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2
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| 1 |
Kd = 11.48 nM
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| 2 |
Ki = 11.22 nM
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CP0422615
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5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)pentan-1-one
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C22H25ClFNO2
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2
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| 1 |
Kd = 12.88 nM
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| 2 |
Ki = 12.02 nM
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CP0422616
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4-(4-chlorophenyl)-1-[5-(4-fluorophenyl)pent-4-ynyl]piperidin-4-ol
Show/Hide
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C22H23ClFNO
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2
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| 1 |
Kd = 17.78 nM
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| 2 |
Ki = 19.05 nM
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CP0433998
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1-(4-chlorophenyl)-4-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]butan-1-one
Show/Hide
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C21H23ClFNO2
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2
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| 1 |
Kd = 18.62 nM
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| 2 |
Ki = 17.78 nM
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CP0418402
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4-(4-chlorophenyl)-1-[5-(4-fluorophenyl)pentyl]piperidin-4-ol
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C22H27ClFNO
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2
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| 1 |
Kd = 21.88 nM
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| 2 |
Ki = 21.88 nM
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CP0080249
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4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride
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C20H22ClFN2O
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2
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| 1 |
Kd = 28.18 nM
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| 2 |
Ki = 29.51 nM
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CP0418401
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4-(4-chlorophenyl)-1-[2-[(1R,2R)-2-(4-fluorophenyl)cyclopropyl]ethyl]piperidin-4-ol
Show/Hide
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C22H25ClFNO
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2
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| 1 |
Kd = 30.9 nM
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| 2 |
Ki = 29.51 nM
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CP0433997
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4-(4-hydroxy-4-phenylpiperidin-1-yl)-1-phenylbutan-1-one
Show/Hide
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C21H25NO2
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2
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| 1 |
Kd = 30.9 nM
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| 2 |
Ki = 32.36 nM
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CP0418400
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4-(4-chlorophenyl)-1-[(Z)-4-(4-fluorophenyl)but-3-enyl]piperidin-4-ol
Show/Hide
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C21H23ClFNO
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2
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| 1 |
Kd = 32.36 nM
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| 2 |
Ki = 29.51 nM
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CP0422619
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(3-fluorophenyl)butan-1-one
Show/Hide
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C21H23ClFNO2
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2
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| 1 |
Kd = 40.74 nM
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| 2 |
Ki = 38.02 nM
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CP0468007
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,3-difluorophenyl)butan-1-one
Show/Hide
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C21H22ClF2NO2
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2
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| 1 |
Kd = 52.48 nM
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| 2 |
Ki = 46.77 nM
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CP0422596
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,6-difluorophenyl)butan-1-one
Show/Hide
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C21H22ClF2NO2
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2
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| 1 |
Kd = 60.26 nM
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| 2 |
Ki = 63.1 nM
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CP0433996
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4-(4-chlorophenyl)-1-[3-(4-fluorophenyl)propyl]piperidin-4-ol
Show/Hide
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C20H23ClFNO
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2
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| 1 |
Kd = 66.07 nM
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| 2 |
Ki = 61.66 nM
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CP0439934
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4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)but-3-ynyl]piperidin-4-ol
Show/Hide
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C21H21ClFNO
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2
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| 1 |
Kd = 70.79 nM
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| 2 |
Ki = 74.13 nM
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CP0358314
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4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
Show/Hide
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C21H25ClFNO2
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2
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| 1 |
Kd = 91.2 nM
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| 2 |
Ki = 91.2 nM
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CP0421005
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,4-difluorophenyl)butan-1-one
Show/Hide
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C21H22ClF2NO2
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2
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| 1 |
Kd = 120.23 nM
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| 2 |
Ki = 83.18 nM
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CP0554566
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,5-difluorophenyl)butan-1-one
Show/Hide
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C21H22ClF2NO2
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2
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| 1 |
Kd = 141.25 nM
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| 2 |
Ki = 112.2 nM
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CP0439936
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3-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)propan-1-one
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C23H26Cl2FN3O3S
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2
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| 1 |
Kd = 144.54 nM
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| 2 |
Ki = 131.83 nM
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CP0418397
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4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(3,5-difluorophenyl)butan-1-one
Show/Hide
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C21H22ClF2NO2
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2
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| 1 |
Kd = 213.8 nM
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| 2 |
Ki = 169.82 nM
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CP0468006
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4-(4-chlorophenyl)-1-[3-(4-fluorophenyl)prop-2-ynyl]piperidin-4-ol
Show/Hide
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C20H19ClFNO
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2
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| 1 |
Kd = 288.4 nM
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| 2 |
Ki = 281.84 nM
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CP0343133
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(S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C19H25NOS
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2
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| 1 |
Ki = 0.06 nM
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| 2 |
Ki = 20 nM
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CP0448444
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6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C19H25NOS
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2
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| 1 |
Ki = 0.14 nM
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| 2 |
Ki = 24 nM
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CP0408135
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N-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H28FN3O2S
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1
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| 1 |
Ki = 0.3 nM
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CP0374327
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(R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C21H27NO
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2
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| 1 |
Ki = 0.5 nM
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| 2 |
Ki = 19 nM
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CP0437030
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6-Propylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
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C13H19NO
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2
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| 1 |
Ki = 0.5 nM
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| 2 |
Ki = 285 nM
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CP0439589
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7-(Methyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C14H21NO
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2
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| 1 |
Ki = 0.67 nM
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| 2 |
Ki = 190 nM
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CP0468855
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N-[3-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H26FN3O2S
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1
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| 1 |
Ki = 0.7 nM
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CP0442595
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7-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C19H25NOS
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2
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| 1 |
Ki = 0.76 nM
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| 2 |
Ki = 59 nM
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CP0461293
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H28N4O2S2
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1
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| 1 |
Ki = 0.9 nM
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CP0395875
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H26FN3O3S
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1
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| 1 |
Ki = 1 nM
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CP0399032
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6-chloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H27ClFN3O3S
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1
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| 1 |
Ki = 1 nM
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CP0472939
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3-chloro-N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]benzenesulfonamide
Show/Hide
|
C23H25Cl2N3O2S
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1
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| 1 |
Ki = 1 nM
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CP0440755
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
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C26H28FN3O3S
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1
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| 1 |
Ki = 1.1 nM
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CP0412072
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(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO2S
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1
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| 1 |
Ki = 1.14 nM
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CP0447245
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6-chloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H25ClFN3O3S2
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1
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| 1 |
Ki = 1.2 nM
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CP0337657
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7-[4-[4-[1-[(3-chlorophenyl)methyl]indol-4-yl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C32H35ClN4O2
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1
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| 1 |
Ki = 1.3 nM
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CP0398684
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7-[4-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C31H34N4O4S
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1
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| 1 |
Ki = 1.3 nM
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CP0440753
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5-chloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C25H27ClFN3O3S2
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1
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| 1 |
Ki = 1.5 nM
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CP0393444
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N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-hydroxybenzenesulfonamide
Show/Hide
|
C21H22ClN3O3S
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1
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| 1 |
Ki = 1.5 nM
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CP0513529
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N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-fluorobenzenesulfonamide
Show/Hide
|
C22H23ClFN3O2S
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1
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| 1 |
Ki = 1.7 nM
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CP0436652
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-fluorobenzenesulfonamide
Show/Hide
|
C23H25ClFN3O2S
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1
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| 1 |
Ki = 1.8 nM
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CP0443093
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5-fluoro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C25H27F2N3O3S2
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1
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| 1 |
Ki = 1.9 nM
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CP0307921
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
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1
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| 1 |
Ki = 2 nM
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CP0461294
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N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C24H26N4O2S2
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1
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| 1 |
Ki = 2.2 nM
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CP0393441
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-1-sulfonamide
Show/Hide
|
C27H28ClN3O2S
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1
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| 1 |
Ki = 2.3 nM
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CP0408141
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N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-fluorobenzenesulfonamide
Show/Hide
|
C21H21ClFN3O2S
|
1
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| 1 |
Ki = 2.4 nM
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CP0405626
|
7-(Ethyl-methyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C13H19NO
|
2
|
| 1 |
Ki = 2.5 nM
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| 2 |
Ki = 173 nM
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CP0403349
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C24H28ClN3O2S
|
1
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| 1 |
Ki = 2.5 nM
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CP0413408
|
N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-hydroxybenzenesulfonamide
Show/Hide
|
C23H26ClN3O3S
|
1
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| 1 |
Ki = 2.5 nM
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CP0408139
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-hydroxybenzenesulfonamide
Show/Hide
|
C22H24ClN3O3S
|
1
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| 1 |
Ki = 2.6 nM
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CP0474916
|
N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H28ClN3O2S
|
1
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| 1 |
Ki = 2.6 nM
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CP0413409
|
4-chloro-N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C22H23Cl2N3O2S
|
1
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| 1 |
Ki = 2.7 nM
|
|
|
|
CP0475024
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-1-sulfonamide
Show/Hide
|
C26H26ClN3O2S
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0921606
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-1,3-benzothiazol-2-amine
Show/Hide
|
C22H28N4O2S
|
1
|
| 1 |
Ki = 2.818 nM
|
|
|
|
CP0447214
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]naphthalene-1-sulfonamide
Show/Hide
|
C26H28FN3O3S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0393440
|
N-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C24H28FN3O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0392694
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]quinazolin-4-amine
Show/Hide
|
C26H33N5
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0395870
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]thiophene-2-sulfonamide
Show/Hide
|
C19H24N4O2S3
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0921607
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-1,3-benzothiazole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 3.236 nM
|
|
|
|
CP0162288
|
7-Amino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C10H13NO
|
2
|
| 1 |
Ki = 3.3 nM
|
|
|
| 2 |
Ki = 78 nM
|
|
|
|
CP0393445
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H24ClN3O2S
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0404236
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]thiophene-2-carboxamide
Show/Hide
|
C23H31N3OS
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0393439
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C22H23ClFN3O2S
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0440757
|
3-chloro-4-fluoro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C21H22ClF2N3O3S
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0436651
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H26ClN3O2S
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0406988
|
7-Propylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C13H19NO
|
2
|
| 1 |
Ki = 3.8 nM
|
|
|
| 2 |
Ki = 836 nM
|
|
|
|
CP0486995
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]naphthalene-1-sulfonamide
Show/Hide
|
C25H26FN3O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0073285
|
6-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]-2,4-dimethyl-7-phenylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C29H33N7O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0463656
|
N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C23H25ClFN3O2S
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0408140
|
4-chloro-N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]benzenesulfonamide
Show/Hide
|
C23H25Cl2N3O2S
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0430512
|
N-[4-[2-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C23H30N4
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0430456
|
N-methyl-N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C23H33N5
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0412623
|
7-[4-[4-(1-benzylindol-3-yl)piperidin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C33H37N3O2
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0380541
|
6-N,6-N-dipropyl-5,6,7,8-tetrahydroquinoline-2,6-diamine
Show/Hide
|
C15H25N3
|
2
|
| 1 |
Ki = 5 nM
|
|
|
| 2 |
Ki = 17.1 nM
|
|
|
|
CP0510211
|
N-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
|
C24H24FN3O3S
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0528055
|
6-fluoro-3-[3-[3-(naphthalen-2-ylsulfonylmethyl)pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C25H25FN2O3S
|
1
|
| 1 |
Ki = 5.248 nM
|
|
|
|
CP0497344
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]thiophene-2-sulfonamide
Show/Hide
|
C19H24N4O3S2
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0428555
|
7-Dimethylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C12H17NO
|
2
|
| 1 |
Ki = 5.4 nM
|
|
|
| 2 |
Ki = 55 nM
|
|
|
|
CP0463415
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C23H26ClN3O2S
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0408136
|
3-chloro-N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C22H23Cl2N3O2S
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0486407
|
N-[4-[(4-phenylpiperazin-1-yl)methyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C21H29N5
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0103545
|
(-)-5-hydroxy-2-(dipropylamino)tetralin
Show/Hide
|
C16H25NO
|
2
|
| 1 |
Ki = 6 nM
|
|
|
| 2 |
Ki = 26 nM
|
|
|
|
CP0413983
|
(2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C16H25NO
|
2
|
| 1 |
Ki = 6 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
|
CP0503028
|
N-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C23H30F3N5
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0505971
|
(4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
|
C23H33N5O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0468505
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C24H25ClN4O2S2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0260687
|
7-[4-[4-[1-[(3-fluorophenyl)methyl]indol-4-yl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C32H35FN4O2
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0511219
|
4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C15H21NO2
|
1
|
| 1 |
Ki = 6.24 nM
|
|
|
|
CP0923262
|
US8952128, 2
Show/Hide
|
C79H103FN16O9
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0398029
|
N-[4-[3-(4-phenylpiperazin-1-yl)propyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C23H33N5
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0483771
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
|
C20H22Cl2N4O2S2
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0461307
|
5-fluoro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H25F2N3O3S2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0395871
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25FN4O2S3
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0082770
|
(-)-3-(1-Propyl-piperidin-3-yl)-phenol
Show/Hide
|
C14H21NO
|
2
|
| 1 |
Ki = 8.5 nM
|
|
|
| 2 |
Ki = 39 nM
|
|
|
|
CP0904368
|
US8952128, 41
Show/Hide
|
C87H111N17O11S
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0395869
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H28N4O2S2
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0443102
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]thiophene-2-sulfonamide
Show/Hide
|
C19H22FN3O3S2
|
1
|
| 1 |
Ki = 8.7 nM
|
|
|
|
CP0123095
|
6-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-2,4-dimethyl-7-phenylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C30H34ClN7O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0443103
|
N-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]naphthalene-1-sulfonamide
Show/Hide
|
C24H24FN3O3S
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0468311
|
5-[5-[3-[1-(3,5-dichlorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26Cl2N6OS
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0429556
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C21H21ClFN3O2S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0931211
|
US8952128, 1
Show/Hide
|
C78H101FN16O9
|
1
|
| 1 |
Ki = 10.8 nM
|
|
|
|
CP0454453
|
3-[(S)-1-(2-Ethyl-thiophen-3-yl)-piperidin-3-yl]-benzonitrile
Show/Hide
|
C18H20N2S
|
2
|
| 1 |
Ki = 11 nM
|
|
|
| 2 |
Ki = 134 nM
|
|
|
|
CP0503336
|
(4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
Show/Hide
|
C22H29Cl2N5
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0461312
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H24FN3O3S2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0412626
|
7-[4-[4-[1-[(2-fluorophenyl)methyl]indol-4-yl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C32H35FN4O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0393443
|
4-chloro-N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]benzenesulfonamide
Show/Hide
|
C21H21Cl2N3O2S
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0471904
|
7-[4-[4-[1-[(4-fluorophenyl)methyl]indol-4-yl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C32H35FN4O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0468503
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C21H26N4O2S2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0791662
|
6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0395881
|
3,4-dichloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C21H22Cl2FN3O3S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0398680
|
7-[4-[4-[1-(benzenesulfonyl)indol-3-yl]piperidin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C32H35N3O4S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0904367
|
US8952128, 28A
Show/Hide
|
C90H117FN18O11
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0480970
|
N-[2-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H24FN3O2S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0409085
|
((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C18H29NO
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0440756
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H28N4O3S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0447097
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C22H24FN5O3S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0466976
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26N4O2S3
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0486987
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H24N4O3S2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0499522
|
3,4-dichloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]benzenesulfonamide
Show/Hide
|
C22H24Cl2FN3O3S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0968833
|
US8952128, 33
Show/Hide
|
C87H111N17O12S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0395876
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C22H25N5O2S3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0447122
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H26FN3O3S
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0957178
|
US8952128, 6A
Show/Hide
|
C78H100F2N16O9S
|
1
|
| 1 |
Ki = 16.9 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
1
|
| 1 |
Ki = 16.98 nM
|
|
|
|
CP0395874
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C23H28FN3O3S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0462037
|
N-[3-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C23H26FN3O2S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0234696
|
(3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole
Show/Hide
|
C16H21NO
|
2
|
| 1 |
Ki = 18 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0486986
|
N-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
|
C23H24N4O2S2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0902275
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C21H28Cl2N4S
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
|
CP0930840
|
US8952128, 48
Show/Hide
|
C79H103FN16O11S
|
1
|
| 1 |
Ki = 19.4 nM
|
|
|
|
CP0468309
|
4-methyl-5-[4-methyl-5-[3-[1-[2-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
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C23H27F3N6O2S
|
1
|
| 1 |
Ki = 19.95 nM
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CP0551501
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3-[3-[3-[(3,4-dimethylphenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
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C23H27FN2O3S
|
1
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| 1 |
Ki = 19.95 nM
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CP0059541
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(3-Phenoxy-propyl)-(2-o-tolyloxy-ethyl)-amine
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C18H23NO2
|
1
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| 1 |
Ki = 20 nM
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CP0404640
|
N,N-dipropyl-4,5,6,7-tetrahydro-1-benzothiophen-5-amine
Show/Hide
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C14H23NS
|
1
|
| 1 |
Ki = 20 nM
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CP0440062
|
N-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
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C21H24FN3O3S
|
1
|
| 1 |
Ki = 20 nM
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CP0379281
|
7-[4-[4-(1-benzylindol-4-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C32H36N4O2
|
1
|
| 1 |
Ki = 20 nM
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CP0472938
|
N-[2-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
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C22H24FN3O2S
|
1
|
| 1 |
Ki = 20 nM
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CP0411521
|
2-[3-[4-[1-[(2-fluorophenyl)methyl]indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
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C29H31FN4O2
|
1
|
| 1 |
Ki = 21 nM
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CP0440416
|
3-((S)-1-Phenethyl-piperidin-3-yl)-benzonitrile
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C20H22N2
|
2
|
| 1 |
Ki = 22 nM
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| 2 |
Ki > 217 nM
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CP0077360
|
N-[2-(3-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
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C17H20ClNO2
|
1
|
| 1 |
Ki = 22 nM
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CP0447218
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-3-sulfonamide
Show/Hide
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C24H26FN3O3S2
|
1
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| 1 |
Ki = 22 nM
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CP0877515
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6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine
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C21H29Cl2N5S
|
1
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| 1 |
Ki = 22.39 nM
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CP0917644
|
US8952128, 16
Show/Hide
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C101H133N21O14S2
|
1
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| 1 |
Ki = 22.5 nM
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CP0468502
|
6-chloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C25H25ClFN3O3S
|
1
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| 1 |
Ki = 23 nM
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CP0411522
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7-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C30H32N4O4S
|
1
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| 1 |
Ki = 23 nM
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CP0282007
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6-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]-2,4-dimethyl-7-phenylpurino[7,8-a]imidazole-1,3-dione
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C29H32ClN7O2
|
1
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| 1 |
Ki = 23 nM
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CP0393442
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3-chloro-N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]benzenesulfonamide
Show/Hide
|
C21H21Cl2N3O2S
|
1
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| 1 |
Ki = 23 nM
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CP0148485
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6-[5-[4-(2-hydroxyphenyl)piperazin-1-yl]pentyl]-2,4-dimethyl-7-phenylpurino[7,8-a]imidazole-1,3-dione
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C30H35N7O3
|
1
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| 1 |
Ki = 24 nM
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CP0466921
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N-[4-[2-(4-pyridin-3-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
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C21H30N6
|
1
|
| 1 |
Ki = 25 nM
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CP0443106
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
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C23H25FN4O3S2
|
1
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| 1 |
Ki = 25 nM
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CP0917645
|
US8952128, 37
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C87H109N17O12S
|
1
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| 1 |
Ki = 25.3 nM
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CP0919310
|
US8952128, 6B
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C78H100F2N16O9S
|
1
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| 1 |
Ki = 25.4 nM
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CP0300421
|
3-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-1H-indole
Show/Hide
|
C20H20N2
|
1
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| 1 |
Ki = 25.8 nM
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CP0447213
|
3-chloro-4-fluoro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]benzenesulfonamide
Show/Hide
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C22H24ClF2N3O3S
|
1
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| 1 |
Ki = 26 nM
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CP0461305
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
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C21H24N6O2S2
|
1
|
| 1 |
Ki = 26 nM
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CP0424242
|
3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C21H22N2O
|
1
|
| 1 |
Ki = 26.9 nM
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CP0413018
|
6-N,6-N-dipropyl-6,7-dihydro-5H-cyclopenta[f][1,3]benzothiazole-2,6-diamine
Show/Hide
|
C16H23N3S
|
1
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| 1 |
Ki = 27 nM
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CP0448483
|
N,N-dipropyl-4,5,6,7-tetrahydro-1-benzothiophen-6-amine
Show/Hide
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C14H23NS
|
1
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| 1 |
Ki = 27 nM
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CP0447123
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3,4-dichlorobenzenesulfonamide
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|
C21H24Cl2N4O2S2
|
1
|
| 1 |
Ki = 27 nM
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CP0468504
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide
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|
C21H23F3N4O3S2
|
1
|
| 1 |
Ki = 27 nM
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CP0473172
|
6-chloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClFN3O3S2
|
1
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| 1 |
Ki = 27 nM
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CP0482709
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C21H23N5O2S3
|
1
|
| 1 |
Ki = 27 nM
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CP0121966
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6-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-2,4,7-trimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C26H35N7O2
|
1
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| 1 |
Ki = 27 nM
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CP0395430
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C22H31N5
|
1
|
| 1 |
Ki = 28 nM
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CP0960068
|
US8952128, 5
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C87H110FN17O11S
|
1
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| 1 |
Ki = 28.5 nM
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CP0421428
|
US10562853, Compound 60
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C25H29ClF2N2O3
|
1
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| 1 |
Ki = 28.84 nM
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CP0482852
|
3-[(S)-1-(3-Phenyl-propyl)-piperidin-3-yl]-benzonitrile
Show/Hide
|
C21H24N2
|
2
|
| 1 |
Ki = 29 nM
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| 2 |
Ki = 60 nM
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CP0429321
|
2-[3-[4-(1-benzylindol-3-yl)piperidin-1-yl]propoxy]benzamide
Show/Hide
|
C30H33N3O2
|
1
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| 1 |
Ki = 29 nM
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CP0486993
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H23ClN4O3S2
|
1
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| 1 |
Ki = 30 nM
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CP0488670
|
N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzofuran-2-sulfonamide
Show/Hide
|
C23H24FN3O4S
|
1
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| 1 |
Ki = 30.2 nM
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CP0926705
|
US8952128, 6C
Show/Hide
|
C78H101FN16O9S
|
1
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| 1 |
Ki = 30.3 nM
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CP0398683
|
2-[3-[4-(1-benzylindol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propoxy]benzamide
Show/Hide
|
C30H31N3O2
|
1
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| 1 |
Ki = 31 nM
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CP0414386
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[2-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7OS
|
1
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| 1 |
Ki = 31.62 nM
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CP0414727
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[3-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H26F3N7S
|
1
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| 1 |
Ki = 31.62 nM
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CP0957179
|
US8952128, 6D
Show/Hide
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C78H101FN16O9S
|
1
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| 1 |
Ki = 31.8 nM
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CP0960070
|
US8952128, 13
Show/Hide
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C87H110FN17O12S
|
1
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| 1 |
Ki = 32.5 nM
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CP0468501
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C22H23F4N3O4S
|
1
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| 1 |
Ki = 33 nM
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CP0044536
|
(2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C16H25NO
|
2
|
| 1 |
Ki = 34 nM
|
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| 2 |
Ki = 56 nM
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CP0957180
|
US8952128, 7
Show/Hide
|
C77H101N17O10S
|
1
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| 1 |
Ki = 34.3 nM
|
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CP0489949
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1-benzothiophene-3-sulfonamide
Show/Hide
|
C23H24FN3O3S2
|
1
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| 1 |
Ki = 36 nM
|
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CP0506619
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C20H22ClFN4O2S2
|
1
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| 1 |
Ki = 37 nM
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CP0393455
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-1-sulfonamide
Show/Hide
|
C25H24ClN3O2S
|
1
|
| 1 |
Ki = 37 nM
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CP0375682
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]cyclohexyl]cyclohexanecarboxamide
Show/Hide
|
C25H39N3O
|
1
|
| 1 |
Ki = 38 nM
|
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CP0957614
|
US8952128, 31::US8952128, 43
Show/Hide
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C87H111N17O11S
|
1
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| 1 |
Ki = 38.6 nM
|
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CP0503327
|
N-[4-[2-[methyl(2-phenylethyl)amino]ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C21H30N4
|
1
|
| 1 |
Ki = 39 nM
|
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CP0510212
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C21H24ClFN4O2S2
|
1
|
| 1 |
Ki = 39 nM
|
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CP0957613
|
US8952128, 9
Show/Hide
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C101H133N21O11S2
|
1
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| 1 |
Ki = 39.2 nM
|
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CP0396195
|
2-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
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| 1 |
Ki = 39.81 nM
|
|
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CP0964148
|
US8952128, 28
Show/Hide
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C83H108FN17O11
|
1
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| 1 |
Ki = 39.9 nM
|
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CP0398681
|
7-[4-[4-[1-(benzenesulfonyl)indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C32H33N3O4S
|
1
|
| 1 |
Ki = 40 nM
|
|
|
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CP0952344
|
US8952128, 6E
Show/Hide
|
C78H97F5N16O9S
|
1
|
| 1 |
Ki = 40.4 nM
|
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CP0391260
|
(4aS,10bR)-4-propyl-3,4a,5,10b-tetrahydro-1H-chromeno[3,4-d][1,3]oxazin-9-ol
Show/Hide
|
C14H19NO3
|
2
|
| 1 |
Ki = 42 nM
|
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| 2 |
Ki = 1183 nM
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CP0446525
|
1-(benzenesulfonyl)-4-(4-propylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 42 nM
|
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CP0458499
|
N-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C20H24N4O2S2
|
1
|
| 1 |
Ki = 43 nM
|
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CP0468506
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H27FN4O2S3
|
1
|
| 1 |
Ki = 44 nM
|
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CP0473171
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H28N4O3S
|
1
|
| 1 |
Ki = 44 nM
|
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CP0441717
|
2-[3-[4-[1-[(4-fluorophenyl)methyl]indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C29H31FN4O2
|
1
|
| 1 |
Ki = 44 nM
|
|
|
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CP0408137
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H24ClN3O2S
|
1
|
| 1 |
Ki = 44 nM
|
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|
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CP0447124
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25ClN4O2S3
|
1
|
| 1 |
Ki = 45 nM
|
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CP0445063
|
2-[3-[4-[1-[(3-fluorophenyl)methyl]indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C29H31FN4O2
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0961982
|
US8952128, 3
Show/Hide
|
C80H105FN16O9
|
1
|
| 1 |
Ki = 45.2 nM
|
|
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CP0497229
|
N-[4-[2-[4-(1,3-thiazol-2-yl)piperazin-1-yl]ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C19H28N6S
|
1
|
| 1 |
Ki = 46 nM
|
|
|
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CP0440922
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H27FN4O3S2
|
1
|
| 1 |
Ki = 46 nM
|
|
|
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CP0481185
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C22H26N6O2S2
|
1
|
| 1 |
Ki = 46 nM
|
|
|
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CP0552785
|
N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H26FN3O3S
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0922736
|
US8952128, 29A
Show/Hide
|
C81H106FN17O10
|
1
|
| 1 |
Ki = 46.8 nM
|
|
|
|
CP0380569
|
8-N,8-N-dipropyl-8,9-dihydro-7H-pyrano[2,3-g][1,3]benzothiazole-2,8-diamine
Show/Hide
|
C16H23N3OS
|
2
|
| 1 |
Ki = 47 nM
|
|
|
| 2 |
Ki = 5920 nM
|
|
|
|
CP0389008
|
1-(benzenesulfonyl)-4-[4-[4-(4-fluorophenoxy)butyl]piperazin-1-yl]indole
Show/Hide
|
C28H30FN3O3S
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0448607
|
(-)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester
Show/Hide
|
C15H20F3NO3S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0447121
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C22H25F3N4O3S2
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0461314
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H24N4O2S3
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0447107
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C25H27ClN4O2S2
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0448100
|
(3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole
Show/Hide
|
C16H21NO
|
2
|
| 1 |
Ki = 50 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0532876
|
3-[3-[3-[(3,4-dichlorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
|
C21H21Cl2FN2O3S
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0395872
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C25H27ClN4O3S
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0039002
|
1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one(Azaperone)
Show/Hide
|
C19H22FN3O
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0528047
|
5-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H25ClFN3O3S2
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0528228
|
N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-3-sulfonamide
Show/Hide
|
C23H24FN3O3S2
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0534014
|
6-fluoro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23F2N3O3S2
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0395873
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25ClN4O3S2
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0549990
|
N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H24FN3O3S2
|
1
|
| 1 |
Ki = 54.95 nM
|
|
|
|
CP0447212
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]thiophene-2-sulfonamide
Show/Hide
|
C18H22N4O3S2
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0401215
|
(R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C16H25NO
|
2
|
| 1 |
Ki = 55.1 nM
|
|
|
| 2 |
Ki = 90 nM
|
|
|
|
CP0506649
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]thiophene-2-sulfonamide
Show/Hide
|
C18H22N4O2S3
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0447151
|
N-[4-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C25H30ClN3O2S
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0887496
|
US8952128, 10
Show/Hide
|
C78H101FN16O11S
|
1
|
| 1 |
Ki = 56.4 nM
|
|
|
|
CP0453529
|
6-N,6-N-dipropyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Show/Hide
|
C13H23N3S
|
2
|
| 1 |
Ki = 57 nM
|
|
|
| 2 |
Ki = 462 nM
|
|
|
|
CP0440055
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
|
C21H24Cl2N4O3S
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0389596
|
6-[5-[4-(3,4-dichlorophenyl)piperazin-1-yl]pentyl]-2,4,7-trimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C25H31Cl2N7O2
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0059544
|
(3-Phenoxy-propyl)-(2-m-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0396191
|
5-[5-[3-[(2R,3S)-2-(3,5-dichlorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25Cl2N5OS
|
1
|
| 1 |
Ki = 61.66 nM
|
|
|
|
CP0411523
|
2-[3-[4-[1-(benzenesulfonyl)indol-3-yl]piperidin-1-yl]propoxy]benzamide
Show/Hide
|
C29H31N3O4S
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0429322
|
1-(benzenesulfonyl)-4-[4-(4-phenoxybutyl)piperazin-1-yl]indole
Show/Hide
|
C28H31N3O3S
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0435202
|
3-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-methoxy-1H-indole
Show/Hide
|
C21H22N2O
|
1
|
| 1 |
Ki = 62.7 nM
|
|
|
|
CP0497340
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C21H23F3N4O4S
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0476087
|
4-methyl-5-[4-methyl-5-[3-[(2R,3R)-2-[2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0146487
|
(2-Phenoxy-ethyl)-(3-p-tolyloxy-propyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0481184
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C23H25F4N3O4S
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0902273
|
6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C21H30N4OS
|
1
|
| 1 |
Ki = 64.57 nM
|
|
|
|
CP0445694
|
5-[5-[3-[(2S,3S)-2-(3,5-dichlorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25Cl2N5OS
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0488653
|
1-(benzenesulfonyl)-4-[4-[3-(4-fluorophenoxy)propyl]piperazin-1-yl]indole
Show/Hide
|
C27H28FN3O3S
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0494035
|
N-[3-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C24H28ClN3O2S
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0963705
|
US8952128, 17
Show/Hide
|
C101H133N21O13S2
|
1
|
| 1 |
Ki = 67.6 nM
|
|
|
|
CP0188400
|
9-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]-1,3-dimethylpurino[7,8-a]pyrimidine-2,4,8-trione
Show/Hide
|
C24H28ClN7O3
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0397448
|
2-[3-[(3S)-1-propylpiperidin-3-yl]phenyl]acetonitrile
Show/Hide
|
C16H22N2
|
2
|
| 1 |
Ki = 69 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0380664
|
7-[4-[2-(1-benzylindol-3-yl)ethylamino]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0424241
|
3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C18H18N2S
|
1
|
| 1 |
Ki = 71.9 nM
|
|
|
|
CP0502546
|
(S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
Show/Hide
|
C21H25ClFNO2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0395221
|
[3-[(3S)-1-(2-phenylethyl)piperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
|
C20H22F3NO3S
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0398682
|
7-[4-[4-(1-benzylindol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C33H35N3O2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0405425
|
(cis)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO2S
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0445066
|
2-[3-[4-[1-[(3-chlorophenyl)methyl]indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C29H31ClN4O2
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0893853
|
US8952128, 14
Show/Hide
|
C78H101FN16O10S
|
1
|
| 1 |
Ki = 76.5 nM
|
|
|
|
CP0447211
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C21H24ClFN4O3S
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0488217
|
2-[4-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]butoxy]benzamide
Show/Hide
|
C29H32N4O4S
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0923263
|
US8952128, 11
Show/Hide
|
C77H101N17O11S
|
1
|
| 1 |
Ki = 79.7 nM
|
|
|
|
CP0462080
|
1-(benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0960072
|
US8952128, 47
Show/Hide
|
C102H133FN20O11S2
|
1
|
| 1 |
Ki = 84.2 nM
|
|
|
|
CP0899498
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C22H32N4OS
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0424239
|
3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C21H22N2O
|
1
|
| 1 |
Ki = 87.3 nM
|
|
|
|
CP0420370
|
N,N-dimethyl-3-[(3S)-1-propylpiperidin-3-yl]benzenesulfonamide
Show/Hide
|
C16H26N2O2S
|
2
|
| 1 |
Ki = 91 nM
|
|
|
| 2 |
Ki = 227 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0546332
|
6-fluoro-3-[3-[3-[(3-methylphenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C22H25FN2O3S
|
1
|
| 1 |
Ki = 93.33 nM
|
|
|
|
CP0441724
|
2-[3-[4-(1-benzylindol-4-yl)piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C29H32N4O2
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0462048
|
1-(benzenesulfonyl)-6-(4-propylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0528049
|
6-fluoro-3-[3-[3-[[4-(trifluoromethyl)phenyl]sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C22H22F4N2O3S
|
1
|
| 1 |
Ki = 95.5 nM
|
|
|
|
CP0373104
|
3-((S)-1-sec-Butyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C16H22N2
|
2
|
| 1 |
Ki = 98 nM
|
|
|
| 2 |
Ki = 187 nM
|
|
|
|
CP0447152
|
N-[4-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H30ClN3O2S
|
1
|
| 1 |
Ki = 99 nM
|
|
|
|
CP0447262
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C22H26N6O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0414387
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[3-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7OS
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0414436
|
3-[5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Show/Hide
|
C23H26N8S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0462036
|
N-[3-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H28ClN3O2S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0960069
|
US8952128, 6
Show/Hide
|
C78H101FN16O9S
|
1
|
| 1 |
Ki = 100.9 nM
|
|
|
|
CP0526678
|
(S)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol
Show/Hide
|
C19H24FN3O
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0448764
|
3-((S)-1-Isopropyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H20N2
|
2
|
| 1 |
Ki = 106 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0519720
|
6-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-2,4,7-trimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C25H32ClN7O2
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0424237
|
5-ethoxy-3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0430235
|
N-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C21H28N4
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0379282
|
1-(benzenesulfonyl)-4-[4-[3-(2-propan-2-yloxyphenoxy)propyl]piperazin-1-yl]indole
Show/Hide
|
C30H35N3O4S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0050117
|
N-[2-(2-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNO2
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0435204
|
5-methoxy-3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0488671
|
6-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClFN3O3S2
|
1
|
| 1 |
Ki = 112.2 nM
|
|
|
|
CP0887495
|
US8952128, 8
Show/Hide
|
C101H133N21O12S2
|
1
|
| 1 |
Ki = 112.8 nM
|
|
|
|
CP0887497
|
US8952128, 20
Show/Hide
|
C77H101N17O12S
|
1
|
| 1 |
Ki = 114.6 nM
|
|
|
|
CP0476091
|
4-[4-methyl-5-[3-[(2S,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]thiadiazole
Show/Hide
|
C21H23F3N6S2
|
1
|
| 1 |
Ki = 117.49 nM
|
|
|
|
CP0454875
|
(3-Phenylsulfanyl-propyl)-(2-p-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NOS
|
1
|
| 1 |
Ki = 118 nM
|
|
|
|
CP0449181
|
3-((S)-1-Propyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H20N2
|
2
|
| 1 |
Ki = 119 nM
|
|
|
| 2 |
Ki = 265 nM
|
|
|
|
CP0447817
|
N,N-diethyl-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0389009
|
1-(benzenesulfonyl)-4-[4-[4-(2-propan-2-yloxyphenoxy)butyl]piperazin-1-yl]indole
Show/Hide
|
C31H37N3O4S
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0519883
|
7-[4-[2-[1-(benzenesulfonyl)indol-3-yl]ethylamino]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C29H31N3O4S
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0282006
|
6-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]-2,4,7-trimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C24H30ClN7O2
|
1
|
| 1 |
Ki = 123 nM
|
|
|
|
CP0398325
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]thiadiazole
Show/Hide
|
C21H23F3N6S2
|
1
|
| 1 |
Ki = 128.82 nM
|
|
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|
CP0528053
|
3-chloro-4-fluoro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C21H22ClF2N3O3S
|
1
|
| 1 |
Ki = 128.82 nM
|
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|
CP0442593
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-methyl-amine
Show/Hide
|
C12H17NO
|
1
|
| 1 |
Ki = 131 nM
|
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|
|
CP0435206
|
5-ethoxy-3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 132 nM
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CP0403814
|
(S)-1-Propyl-3-(3-thiophen-3-yl-phenyl)-piperidine
Show/Hide
|
C18H23NS
|
2
|
| 1 |
Ki = 134 nM
|
|
|
| 2 |
Ki > 217 nM
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CP0551500
|
3-[3-[3-[(3-chloro-4-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
|
C21H21ClF2N2O3S
|
1
|
| 1 |
Ki = 134.9 nM
|
|
|
|
CP0946851
|
US8952128, 29
Show/Hide
|
C95H123N19O9S2
|
1
|
| 1 |
Ki = 135.2 nM
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|
|
CP0462047
|
1-(benzenesulfonyl)-6-(4-ethylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 136 nM
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|
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CP0127400
|
(-)-Pramipexole
Show/Hide
|
C10H17N3S
|
1
|
| 1 |
Ki = 139 nM
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CP0435205
|
5-methoxy-3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C19H20N2OS
|
1
|
| 1 |
Ki = 141 nM
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|
|
|
CP0508131
|
3-[1-(furan-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-5-methoxy-1H-indole
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0059512
|
N-[2-(3,4-dimethylphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0449207
|
3-((S)-1-Propyl-piperidin-3-yl)-benzaldehyde
Show/Hide
|
C15H21NO
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0338014
|
AJ 76
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 145 nM
|
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CP0424240
|
5-methoxy-3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0893854
|
US8952128, 15
Show/Hide
|
C86H110N18O12S
|
1
|
| 1 |
Ki = 149.3 nM
|
|
|
|
CP0435203
|
3-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-5-ethoxy-1H-indole
Show/Hide
|
C22H24N2O
|
1
|
| 1 |
Ki = 151 nM
|
|
|
|
CP0964096
|
6-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C20H28N4OS
|
1
|
| 1 |
Ki = 151.36 nM
|
|
|
|
CP0534012
|
6-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H25ClFN3O3S
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0552784
|
3-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C21H23ClFN3O3S
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0404649
|
2-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
|
C22H25F3N6S2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0414719
|
5-[5-[3-[1-(3-fluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H27FN6OS
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0420012
|
3-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,2-oxazole
Show/Hide
|
C23H27F3N6OS
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
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CP0518055
|
5-[3-[(4-methyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
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CP0412625
|
2-[3-[4-[1-(benzenesulfonyl)indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl]propoxy]benzamide
Show/Hide
|
C29H29N3O4S
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0488674
|
3-[3-[3-[(3-chlorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
|
C21H22ClFN2O3S
|
1
|
| 1 |
Ki = 162.18 nM
|
|
|
|
CP0535812
|
3-[1-[(4-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-5-propan-2-yloxy-1H-indole
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
Ki = 165 nM
|
|
|
|
CP0445692
|
5-[5-[3-[(2S,3S)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 165.96 nM
|
|
|
|
CP0435199
|
5-ethoxy-3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C20H22N2OS
|
1
|
| 1 |
Ki = 166 nM
|
|
|
|
CP0439610
|
(S)-3-(3-Bromo-phenyl)-1-propyl-piperidine
Show/Hide
|
C14H20BrN
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0395880
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C22H25N5O3S2
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0919311
|
US8952128, 24
Show/Hide
|
C77H99N17O10S
|
1
|
| 1 |
Ki = 175.3 nM
|
|
|
|
CP0902274
|
5-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3a,4,6,7,8,8a-hexahydrothiazolo[5,4-c]azepine
Show/Hide
|
C21H30N4OS
|
1
|
| 1 |
Ki = 177.83 nM
|
|
|
|
CP0959002
|
US8952128, 38
Show/Hide
|
C86H110N18O11S
|
1
|
| 1 |
Ki = 179.4 nM
|
|
|
|
CP0483810
|
N-ethyl-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0461007
|
N-[4-[2-(4-pyrazin-2-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C20H29N7
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0523324
|
2-[3-[2-[1-(benzenesulfonyl)indol-3-yl]ethylamino]propoxy]benzamide
Show/Hide
|
C26H27N3O4S
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0408138
|
N-[2-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H26ClN3O2S
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0459059
|
2-(benzenesulfonyl)-4-(4-propylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0456715
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-amine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki = 181 nM
|
|
|
|
CP0959000
|
US8952128, 4
Show/Hide
|
C86H110N18O11S
|
1
|
| 1 |
Ki = 182.5 nM
|
|
|
|
CP0377270
|
[3-[(3S)-1-propylpiperidin-3-yl]phenyl] methanesulfonate
Show/Hide
|
C15H23NO3S
|
2
|
| 1 |
Ki = 192 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0494751
|
9-Oxo-1-propyl-2,3,4a,9,10,10a-hexahydro-1H-4-oxa-9lambda*4*-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3S
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0919306
|
US8952128, 22
Show/Hide
|
C81H106FN17O10
|
1
|
| 1 |
Ki = 199.5 nM
|
|
|
|
CP0404645
|
1-(4-fluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H26FN7S
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0414437
|
5-[3-[[4-methyl-5-(1-methylpyrazol-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H28F3N7S
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0420015
|
2-[5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Show/Hide
|
C23H26N8S
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0943801
|
US8952128, 44
Show/Hide
|
C78H100N16O10S
|
1
|
| 1 |
Ki = 199.6 nM
|
|
|
|
CP0467676
|
1-(benzenesulfonyl)-4-(4-methylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C19H23N3O2S
|
1
|
| 1 |
Ki = 211 nM
|
|
|
|
CP0113424
|
9-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-1,3-dimethylpurino[7,8-a]pyrimidine-2,4,8-trione
Show/Hide
|
C25H30ClN7O3
|
1
|
| 1 |
Ki = 215 nM
|
|
|
|
CP0445670
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzenesulfonamide
Show/Hide
|
C25H28F3N5O2S2
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0573071
|
1-[(2,6-dimethylphenoxy)ethoxyethyl]-4-(2-methoxyphenyl)piperazine hydrochloride (5)
Show/Hide
|
C23H32N2O3
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0523325
|
1-(benzenesulfonyl)-4-[4-[3-(1-benzofuran-6-yloxy)propyl]piperazin-1-yl]indole
Show/Hide
|
C29H29N3O4S
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0395411
|
(3-Phenoxy-propyl)-(2-p-tolylsulfanyl-ethyl)-amine
Show/Hide
|
C18H23NOS
|
1
|
| 1 |
Ki = 222 nM
|
|
|
|
CP0398324
|
5-[5-[3-[(2R,3R)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 223.87 nM
|
|
|
|
CP0454510
|
N-[2-(4-chlorophenoxy)ethyl]-3-phenylsulfanylpropan-1-amine
Show/Hide
|
C17H20ClNOS
|
1
|
| 1 |
Ki = 227 nM
|
|
|
|
CP0059618
|
N-[2-(4-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNO2
|
1
|
| 1 |
Ki = 228 nM
|
|
|
|
CP0404021
|
3-((S)-1-Ethyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C14H18N2
|
2
|
| 1 |
Ki = 235 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0465118
|
5-[5-[3-[(2S,3R)-2-(4-fluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26FN5OS
|
1
|
| 1 |
Ki = 239.88 nM
|
|
|
|
CP0403569
|
[3-[(3S)-1-propylpiperidin-3-yl]phenyl]methanol
Show/Hide
|
C15H23NO
|
2
|
| 1 |
Ki = 240 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0505972
|
CHEMBL349980
Show/Hide
|
C20H29N7
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0409290
|
(R)-1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
|
C20H25NO3
|
1
|
| 1 |
Ki = 244 nM
|
|
|
|
CP0159469
|
N-[2-(4-chlorophenoxy)ethyl]-3-(4-fluorophenoxy)propan-1-amine
Show/Hide
|
C17H19ClFNO2
|
1
|
| 1 |
Ki = 245 nM
|
|
|
|
CP0410831
|
1-(benzenesulfonyl)-5-(4-propylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C21H27N3O2S
|
1
|
| 1 |
Ki = 245 nM
|
|
|
|
CP0405312
|
((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
Show/Hide
|
C20H27NOS
|
2
|
| 1 |
Ki = 250 nM
|
|
|
| 2 |
Ki = 1241 nM
|
|
|
|
CP0059535
|
(2-Phenoxy-ethyl)-(3-phenoxy-propyl)-amine
Show/Hide
|
C17H21NO2
|
1
|
| 1 |
Ki = 251 nM
|
|
|
|
CP0448071
|
1-(3-fluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H26FN7S
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0518051
|
5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[2-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0451585
|
3-((S)-1-Allyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C15H18N2
|
2
|
| 1 |
Ki = 254 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0424236
|
3-[1-(furan-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C18H18N2O
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0386381
|
5-[5-[3-[(2R,3R)-2-(2,4-difluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25F2N5OS
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0488673
|
6-fluoro-3-[3-[3-[(4-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C21H22F2N2O3S
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0441366
|
6-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C24H30ClN7O2
|
1
|
| 1 |
Ki = 259 nM
|
|
|
|
CP0123092
|
6-[5-[4-(2-hydroxyphenyl)piperazin-1-yl]pentyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C24H31N7O3
|
1
|
| 1 |
Ki = 265 nM
|
|
|
|
CP0178983
|
(3-Phenoxy-propyl)-(2-p-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 268 nM
|
|
|
|
CP0445064
|
2-[3-[2-(1-benzylindol-3-yl)ethylamino]propoxy]benzamide
Show/Hide
|
C27H29N3O2
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0479938
|
N,N-dipropyl-5,6,7,8-tetrahydroquinolin-6-amine
Show/Hide
|
C15H24N2
|
2
|
| 1 |
Ki = 272 nM
|
|
|
| 2 |
Ki = 466 nM
|
|
|
|
CP0961984
|
US8952128, 25
Show/Hide
|
C77H99N17O11S
|
1
|
| 1 |
Ki = 272.4 nM
|
|
|
|
CP0448509
|
(7S)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C16H25NO
|
2
|
| 1 |
Ki = 275 nM
|
|
|
| 2 |
Ki = 4777 nM
|
|
|
|
CP0960424
|
US8952128, 27
Show/Hide
|
C90H115FN18O12
|
1
|
| 1 |
Ki = 276.8 nM
|
|
|
|
CP0146505
|
(2-p-Tolyloxy-ethyl)-(3-p-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 277 nM
|
|
|
|
CP0503037
|
(R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol
Show/Hide
|
C21H25ClFNO2
|
1
|
| 1 |
Ki = 279 nM
|
|
|
|
CP0887499
|
US8952128, 42
Show/Hide
|
C89H115FN18O13S
|
1
|
| 1 |
Ki = 285.3 nM
|
|
|
|
CP0429443
|
1-(benzenesulfonyl)-4-[4-(3-phenoxypropyl)piperazin-1-yl]indole
Show/Hide
|
C27H29N3O3S
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0215268
|
N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 291 nM
|
|
|
|
CP0141761
|
(2-p-Tolyloxy-ethyl)-(3-m-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 292 nM
|
|
|
|
CP0476089
|
5-[5-[3-[(2S,3S)-2-(2,4-difluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25F2N5OS
|
1
|
| 1 |
Ki = 295.12 nM
|
|
|
|
CP0551286
|
(2R,3S)-5-[3-[(4-methyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 295.12 nM
|
|
|
|
CP0059513
|
(2-p-Tolyloxy-ethyl)-(3-o-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 296 nM
|
|
|
|
CP0930838
|
US8952128, 34
Show/Hide
|
C78H99FN16O10S
|
1
|
| 1 |
Ki = 298.9 nM
|
|
|
|
CP0077362
|
N-[2-(3-chloro-4-methylphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C18H22ClNO2
|
1
|
| 1 |
Ki = 299 nM
|
|
|
|
CP0558519
|
3-[1-[(3-methoxyphenyl)methyl]-3,6-dihydro-2H-pyridin-4-yl]-5-propan-2-yloxy-1H-indole
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
Ki = 299 nM
|
|
|
|
CP0532871
|
6-fluoro-3-[3-[3-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C22H22F4N2O3S
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0922735
|
US8952128, 26
Show/Hide
|
C78H102N16O9S
|
1
|
| 1 |
Ki = 309 nM
|
|
|
|
CP0040250
|
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
Show/Hide
|
C21H25N3O2S
|
1
|
| 1 |
Ki = 309.03 nM
|
|
|
|
CP0469321
|
2-(benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-1,3-dihydroisoindole
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0443640
|
(S)-3-Piperidin-3-yl-benzonitrile
Show/Hide
|
C12H14N2
|
2
|
| 1 |
Ki = 314 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0404644
|
1-(2-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7OS
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0404651
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7OS
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0443498
|
1-(3-methylphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0447868
|
5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[2-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0447885
|
5-[3-[(4-methyl-5-pyridazin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7S
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0435201
|
3-(1-benzyl-3,6-dihydro-2H-pyridin-4-yl)-5-propan-2-yloxy-1H-indole
Show/Hide
|
C23H26N2O
|
1
|
| 1 |
Ki = 321 nM
|
|
|
|
CP0446528
|
1-(benzenesulfonyl)-6-(1-propylpiperidin-4-yl)-2,3-dihydroindole
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
Ki = 324 nM
|
|
|
|
CP0957182
|
US8952128, 23
Show/Hide
|
C77H101N17O9S
|
1
|
| 1 |
Ki = 328.3 nM
|
|
|
|
CP0930839
|
US8952128, 39
Show/Hide
|
C96H123FN18O9S2
|
1
|
| 1 |
Ki = 329.7 nM
|
|
|
|
CP0510743
|
(2R,3S)-5-[3-[(4-methyl-5-thiophen-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4S2
|
1
|
| 1 |
Ki = 331.13 nM
|
|
|
|
CP0275794
|
5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine
Show/Hide
|
C11H15NO
|
1
|
| 1 |
Ki = 334 nM
|
|
|
|
CP0484978
|
US10562853, Compound 7
Show/Hide
|
C22H25Cl2FN2O3
|
1
|
| 1 |
Ki = 338.84 nM
|
|
|
|
CP0118231
|
9-[5-[4-(2-hydroxyphenyl)piperazin-1-yl]pentyl]-1,3-dimethylpurino[7,8-a]pyrimidine-2,4,8-trione
Show/Hide
|
C25H31N7O4
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0968834
|
US8952128, 35
Show/Hide
|
C95H123N19O10S2
|
1
|
| 1 |
Ki = 345.2 nM
|
|
|
|
CP0401866
|
(2R,3S)-5-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4S2
|
1
|
| 1 |
Ki = 346.74 nM
|
|
|
|
CP0507041
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzonitrile
Show/Hide
|
C26H26F3N5S
|
1
|
| 1 |
Ki = 346.74 nM
|
|
|
|
CP0110881
|
4-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 349 nM
|
|
|
|
CP0474914
|
N-[2-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C23H26ClN3O2S
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0454831
|
N-[2-(4-chlorophenyl)sulfanylethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNOS
|
1
|
| 1 |
Ki = 352 nM
|
|
|
|
CP0398326
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 354.81 nM
|
|
|
|
CP0410826
|
1-(benzenesulfonyl)-4-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 355 nM
|
|
|
|
CP0179022
|
2-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]-1,3-oxazole
Show/Hide
|
C28H28F3N5OS
|
1
|
| 1 |
Ki = 363.08 nM
|
|
|
|
CP0374180
|
(3-Phenoxy-propyl)-(3-p-tolyl-propyl)-amine
Show/Hide
|
C19H25NO
|
1
|
| 1 |
Ki = 364 nM
|
|
|
|
CP0467609
|
2-Phenyl-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C21H25NO2
|
1
|
| 1 |
Ki = 375 nM
|
|
|
|
CP0375804
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki = 380 nM
|
|
|
|
CP0059517
|
3-(4-fluorophenoxy)-N-[2-(4-methylphenoxy)ethyl]propan-1-amine
Show/Hide
|
C18H22FNO2
|
1
|
| 1 |
Ki = 391 nM
|
|
|
|
CP0404648
|
5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0404652
|
1-(3-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7OS
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0404657
|
5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0404661
|
1-(2-fluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H26FN7S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0443497
|
1-[2-fluoro-6-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H25F4N7S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0448069
|
4-[5-[3-[1-(4-fluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-1-methylpyridin-2-one
Show/Hide
|
C24H29FN6OS
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0455671
|
5-[4-methyl-5-[3-[1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1H-pyridin-2-one
Show/Hide
|
C24H27F3N6OS
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0461296
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C22H25F3N4O4S
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0505664
|
(R)-1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-ol
Show/Hide
|
C19H24FN3O
|
1
|
| 1 |
Ki = 403 nM
|
|
|
|
CP0459054
|
1-(benzenesulfonyl)-6-(4-cyclobutylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C22H27N3O2S
|
1
|
| 1 |
Ki = 411 nM
|
|
|
|
CP0221754
|
(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
|
C17H27NO
|
1
|
| 1 |
Ki = 416 nM
|
|
|
|
CP0396192
|
2-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
|
C22H24F3N5S2
|
1
|
| 1 |
Ki = 426.58 nM
|
|
|
|
CP0573889
|
3-[3-[3-[(3,4-difluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
|
C21H21F3N2O3S
|
1
|
| 1 |
Ki = 426.58 nM
|
|
|
|
CP0118234
|
6-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]-2,4,7-trimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C24H31N7O3
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0393312
|
3-Benzyl-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H19NO3
|
1
|
| 1 |
Ki = 436 nM
|
|
|
|
CP0507046
|
(2S,3S)-5-[3-[(4-methyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0564999
|
US10562853, Compound 17
Show/Hide
|
C24H24Cl2FN3O2
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0462058
|
1-(benzenesulfonyl)-5-(4-ethylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C20H25N3O2S
|
1
|
| 1 |
Ki = 438 nM
|
|
|
|
CP0526746
|
N,N-bis(2-thiophen-3-ylethyl)propan-1-amine
Show/Hide
|
C15H21NS2
|
1
|
| 1 |
Ki = 439 nM
|
|
|
|
CP0954982
|
US8952128, 40
Show/Hide
|
C96H124N18O9S2
|
1
|
| 1 |
Ki = 444.9 nM
|
|
|
|
CP0507029
|
1-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]ethanone
Show/Hide
|
C27H29F3N4OS
|
1
|
| 1 |
Ki = 446.68 nM
|
|
|
|
CP0308847
|
(S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine
Show/Hide
|
C15H23NO2S
|
2
|
| 1 |
Ki = 447 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0178952
|
3-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 451 nM
|
|
|
|
CP0398323
|
N-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]cyclohexyl]acetamide
Show/Hide
|
C27H36F3N5OS
|
1
|
| 1 |
Ki = 457.09 nM
|
|
|
|
CP0482470
|
1-(benzenesulfonyl)-6-(4-methylpiperazin-1-yl)-2,3-dihydroindole
Show/Hide
|
C19H23N3O2S
|
1
|
| 1 |
Ki = 458 nM
|
|
|
|
CP0435200
|
5-propan-2-yloxy-3-[1-(thiophen-2-ylmethyl)-3,6-dihydro-2H-pyridin-4-yl]-1H-indole
Show/Hide
|
C21H24N2OS
|
1
|
| 1 |
Ki = 465 nM
|
|
|
|
CP0269448
|
N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 466 nM
|
|
|
|
CP0396194
|
2-[4-methyl-5-[3-[(2S,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
|
C22H24F3N5S2
|
1
|
| 1 |
Ki = 467.74 nM
|
|
|
|
CP0419780
|
2-[4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]acetamide
Show/Hide
|
C27H30F3N5OS
|
1
|
| 1 |
Ki = 467.74 nM
|
|
|
|
CP0419781
|
(2R,3S)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N6S
|
1
|
| 1 |
Ki = 467.74 nM
|
|
|
|
CP0073286
|
6-[5-[4-(2-hydroxyphenyl)piperazin-1-yl]pentyl]-2,4,7-trimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C25H33N7O3
|
1
|
| 1 |
Ki = 468 nM
|
|
|
|
CP0419778
|
(2R,3S)-5-[3-[[5-(furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4OS
|
1
|
| 1 |
Ki = 478.63 nM
|
|
|
|
CP0200768
|
N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
Show/Hide
|
C28H30N4O
|
2
|
| 1 |
Ki = 489.78 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0269449
|
4-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C18H19Cl2N3O
|
1
|
| 1 |
Ki = 495 nM
|
|
|
|
CP0418912
|
7-N,7-N-dipropyl-7,8-dihydro-6H-cyclopenta[g][1,3]benzothiazole-2,7-diamine
Show/Hide
|
C16H23N3S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0404638
|
1-(4-fluoro-3-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H28FN7OS
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0443257
|
5-[5-[3-[1-(2,4-dichlorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26Cl2N6OS
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0468310
|
5-[5-[3-[1-(2,6-difluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26F2N6OS
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0380643
|
2-[3-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]phenyl]-1,3-oxazole
Show/Hide
|
C28H28F3N5OS
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0396193
|
(2R,3S)-5-[3-[[5-(furan-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F3N4OS
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0454452
|
3-((S)-1-Cyclopropylmethyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C16H20N2
|
2
|
| 1 |
Ki = 519 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0395466
|
(3-Phenoxy-propyl)-(3-phenyl-propyl)-amine
Show/Hide
|
C18H23NO
|
1
|
| 1 |
Ki = 519 nM
|
|
|
|
CP0413089
|
N,N-dipropyl-4,5,6,7-tetrahydro-1H-indazol-5-amine
Show/Hide
|
C13H23N3
|
2
|
| 1 |
Ki = 523 nM
|
|
|
| 2 |
Ki > 3333 nM
|
|
|
|
CP0494825
|
7-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C21H27NO
|
1
|
| 1 |
Ki = 524 nM
|
|
|
|
CP0380527
|
(2R,3S)-5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0396198
|
(2S,3S)-2-(2,4-difluorophenyl)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H25F2N5S
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0419779
|
3-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,2-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0476090
|
4-methyl-5-[4-methyl-5-[2-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]ethylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0401205
|
(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO2S
|
1
|
| 1 |
Ki = 533 nM
|
|
|
|
CP0467385
|
7-N,7-N-dipropyl-7,8-dihydro-6H-pyrano[2,3-e][1,3]benzothiazole-2,7-diamine
Show/Hide
|
C16H23N3OS
|
2
|
| 1 |
Ki = 536 nM
|
|
|
| 2 |
Ki = 3510 nM
|
|
|
|
CP0476093
|
(2R,3S)-5-[3-[[4-methyl-5-(1-methylpyrazol-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H27F3N6S
|
1
|
| 1 |
Ki = 537.03 nM
|
|
|
|
CP0420797
|
[(5S,6R)-6-(dipropylamino)-5-methyl-5,6,7,8-tetrahydronaphthalen-1-yl] trifluoromethanesulfonate
Show/Hide
|
C18H26F3NO3S
|
1
|
| 1 |
Ki = 546 nM
|
|
|
|
CP0214556
|
5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
|
C25H27F3N6OS
|
1
|
| 1 |
Ki = 549.54 nM
|
|
|
|
CP0404069
|
((R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
Show/Hide
|
C20H27NOS
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0077361
|
4-[2-(3-Phenoxy-propylamino)-ethoxy]-phenol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Ki = 556 nM
|
|
|
|
CP0410018
|
(2R,3S)-5-[3-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C25H33F3N4S
|
1
|
| 1 |
Ki = 588.84 nM
|
|
|
|
CP0448191
|
(S)-3-(3-Methoxy-phenyl)-1-propyl-piperidine
Show/Hide
|
C15H23NO
|
2
|
| 1 |
Ki = 602 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0507038
|
(2R,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 616.6 nM
|
|
|
|
CP0441462
|
6-Propyl-4,5a,6,7,8,9a-hexahydro-5H-9-oxa-3-thia-6-aza-cyclopenta[a]naphthalene
Show/Hide
|
C13H19NOS
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0404653
|
1-(4-methylphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H29N7S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0404655
|
4-methyl-5-[4-methyl-5-[3-[1-[4-(trifluoromethoxy)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H27F3N6O2S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0414385
|
5-[3-[(4-methyl-5-pyridazin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C23H26F3N7S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0414725
|
1-(2,6-difluorophenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H25F2N7S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0514940
|
5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-(2,4,6-trifluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C22H24F3N7S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0516086
|
4-[5-[3-[1-(4-fluorophenyl)-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-1H-pyridin-2-one
Show/Hide
|
C23H27FN6OS
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0300572
|
3-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzamide
Show/Hide
|
C26H28F3N5OS
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0396201
|
(2S,3S)-5-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0465127
|
4-methyl-5-[4-methyl-5-[3-[(2R,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C23H26F3N5OS
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0552783
|
6-fluoro-3-[3-[3-[(3-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C21H22F2N2O3S
|
1
|
| 1 |
Ki = 645.65 nM
|
|
|
|
CP0415028
|
3-Benzyl-7,8-dimethoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H21NO4
|
1
|
| 1 |
Ki = 659 nM
|
|
|
|
CP0396199
|
(2R,3S)-2-(4-fluorophenyl)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H26FN5S
|
1
|
| 1 |
Ki = 660.69 nM
|
|
|
|
CP0421434
|
US10562853, Compound 6
Show/Hide
|
C22H25ClF2N2O3
|
1
|
| 1 |
Ki = 676.08 nM
|
|
|
|
CP0510730
|
5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
Show/Hide
|
C25H25F3N6S
|
1
|
| 1 |
Ki = 691.83 nM
|
|
|
|
CP0405129
|
Butyl-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine
Show/Hide
|
C15H23NO
|
1
|
| 1 |
Ki = 694 nM
|
|
|
|
CP0121965
|
6-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]-2,4-dimethylpurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C23H29N7O3
|
1
|
| 1 |
Ki = 700 nM
|
|
|
|
CP0465123
|
4-methyl-5-[4-methyl-5-[3-[(2R,3R)-2-phenyl-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 707.95 nM
|
|
|
|
CP0420854
|
(S)-1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
|
C20H25NO3
|
1
|
| 1 |
Ki = 709 nM
|
|
|
|
CP0476096
|
(2S,3S)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H25F4N5S
|
1
|
| 1 |
Ki = 724.44 nM
|
|
|
|
CP0380640
|
(2R,3S)-5-[3-[[4-methyl-5-(8-oxabicyclo[3.2.1]octan-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C26H33F3N4OS
|
1
|
| 1 |
Ki = 741.31 nM
|
|
|
|
CP0405628
|
3-Benzyl-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H19NO2
|
1
|
| 1 |
Ki = 774 nM
|
|
|
|
CP0468306
|
5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
|
C24H27F3N6S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0237860
|
4-methyl-5-[4-methyl-5-[3-[(2S,3R)-2-phenyl-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0510741
|
4-methyl-5-[4-methyl-5-[2-[(2R,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]ethylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C22H24F3N5OS
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0519603
|
5-[5-[3-[(2R,3R)-2-(4-fluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H26FN5OS
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0380480
|
(2R,3S)-5-[3-[[4-methyl-5-(oxan-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H31F3N4OS
|
1
|
| 1 |
Ki = 812.83 nM
|
|
|
|
CP0459368
|
(S)-1-Propyl-3-[3-(2,2,2-trifluoro-ethoxy)-phenyl]-piperidine
Show/Hide
|
C16H22F3NO
|
2
|
| 1 |
Ki = 820 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0076889
|
N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-3-methylbenzamide
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 835 nM
|
|
|
|
CP0476095
|
(2R,3S)-5-[3-[[4-methyl-5-(2-methylpyrazol-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C23H27F3N6S
|
1
|
| 1 |
Ki = 851.14 nM
|
|
|
|
CP0508599
|
(+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO2S
|
1
|
| 1 |
Ki = 854 nM
|
|
|
|
CP0473908
|
1-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridin-2-one
Show/Hide
|
C25H28F3N5OS
|
1
|
| 1 |
Ki = 870.96 nM
|
|
|
|
CP0476097
|
(2S,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 870.96 nM
|
|
|
|
CP0476098
|
(2R,3S)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C24H26F3N5S
|
1
|
| 1 |
Ki = 891.25 nM
|
|
|
|
CP0040962
|
3-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H19ClN4O
|
1
|
| 1 |
Ki = 897 nM
|
|
|
|
CP0375013
|
1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
|
C20H25NO3
|
1
|
| 1 |
Ki = 911 nM
|
|
|
|
CP0479917
|
US10562853, Compound 15
Show/Hide
|
C23H25Cl2FN2O4
|
1
|
| 1 |
Ki = 912.01 nM
|
|
|
|
CP0269450
|
4-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H19ClN4O
|
1
|
| 1 |
Ki = 929 nM
|
|
|
|
CP0476086
|
5-[5-[3-[(2S,3R)-2-(2,4-difluorophenyl)-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H25F2N5OS
|
1
|
| 1 |
Ki = 954.99 nM
|
|
|
|
CP0507030
|
(2R,3S)-5-[3-[[4-methyl-5-[2-(trifluoromethyl)pyridin-3-yl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
|
C25H25F6N5S
|
1
|
| 1 |
Ki = 954.99 nM
|
|
|
|
CP0380641
|
4-methyl-5-[4-methyl-5-[4-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]butylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
|
C24H28F3N5OS
|
1
|
| 1 |
Ki = 977.24 nM
|
|
|
|
CP0380642
|
5-[5-[3-[(2S,3R)-2-[2-fluoro-4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C23H25F4N5OS
|
1
|
| 1 |
Ki = 977.24 nM
|
|
|
|
CP0448943
|
3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carbonitrile
Show/Hide
|
C16H18N2
|
2
|
| 1 |
Ki = 984 nM
|
|
|
| 2 |
Ki > 217 nM
|
|
|
|
CP0462407
|
4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidine-1-carboxamide
Show/Hide
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C25H33F3N6OS
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1
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| 1 |
Ki = 1000 nM
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CP0451515
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3-((S)-1-Methyl-piperidin-3-yl)-benzonitrile
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C13H16N2
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2
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| 1 |
Ki = 1040 nM
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| 2 |
Ki > 217 nM
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CP0390674
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1-(benzenesulfonyl)-4-(1-cyclobutylpiperidin-4-yl)-2,3-dihydroindole
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C23H28N2O2S
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1
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| 1 |
Ki = 1042 nM
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CP0409110
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(5-Cyclopentyloxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-(2-thiophen-2-yl-ethyl)-amine
Show/Hide
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C24H33NOS
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1
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| 1 |
Ki = 1046 nM
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CP0460133
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N-(2-thiophen-2-ylethyl)-N-(2-thiophen-3-ylethyl)propan-1-amine
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C15H21NS2
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1
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| 1 |
Ki = 1080 nM
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CP0396200
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(2R,3S)-5-[3-[[5-(2-methoxypyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
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C25H28F3N5OS
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1
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| 1 |
Ki = 1148.15 nM
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CP0420595
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6-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxamide
Show/Hide
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C26H29F3N6OS
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1
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| 1 |
Ki = 1148.15 nM
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CP0178951
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-4-methylbenzamide
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C20H22N4O
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1
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| 1 |
Ki = 1150 nM
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CP0393326
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3-(4-Chloro-benzyl)-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
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C20H18ClNO2
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1
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| 1 |
Ki = 1170 nM
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CP0422922
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8-Methoxy-3-(4-methyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
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C21H21NO3
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1
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| 1 |
Ki = 1170 nM
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CP0451272
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3-((S)-1-Prop-2-ynyl-piperidin-3-yl)-benzonitrile
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C15H16N2
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2
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| 1 |
Ki = 1178 nM
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| 2 |
Ki > 217 nM
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CP0402371
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(2-Methoxy-5,6,7,8-tetrahydro-quinolin-6-yl)-dipropyl-amine
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C16H26N2O
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2
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| 1 |
Ki = 1202 nM
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| 2 |
Ki > 3333 nM
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CP0211490
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(2R,3S)-5-[3-[[5-(2,6-dimethylpyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
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C26H30F3N5S
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1
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| 1 |
Ki = 1230.27 nM
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CP0465130
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4-methyl-5-[4-methyl-5-[3-[(2S,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
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C23H26F3N5S2
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1
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| 1 |
Ki = 1230.27 nM
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CP0404650
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5-[3-[(4-methyl-5-pyrimidin-5-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H26F3N7S
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1
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| 1 |
Ki = 1258.93 nM
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CP0414435
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1-[4-fluoro-2-(trifluoromethyl)phenyl]-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H25F4N7S
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1
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| 1 |
Ki = 1258.93 nM
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CP0398329
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5-[5-[3-[(2S,3R)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
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C23H25F4N5OS
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1
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| 1 |
Ki = 1288.25 nM
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CP0443099
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N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
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C23H26N4O3S2
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1
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| 1 |
Ki = 1300 nM
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CP0159467
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N-[2-(4-chlorophenoxy)ethyl]-3-(4-methylphenoxy)propan-1-amine
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C18H22ClNO2
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1
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| 1 |
Ki = 1320 nM
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CP0178940
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N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
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C19H22ClN3O
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1
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| 1 |
Ki = 1330 nM
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CP0399463
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4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidin-2-one
Show/Hide
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C24H30F3N5OS
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1
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| 1 |
Ki = 1348.96 nM
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CP0507039
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(2S,3S)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C24H26F3N5S
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1
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| 1 |
Ki = 1348.96 nM
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CP0431710
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6-N-propyl-6,7-dihydro-5H-cyclopenta[f][1,3]benzothiazole-2,6-diamine
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C13H17N3S
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1
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| 1 |
Ki = 1350 nM
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CP0507045
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(2R,3S)-5-[3-[(4-methyl-5-pyridazin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 1380.38 nM
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CP0269451
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N-[2-(4-nitrophenoxy)ethyl]-3-phenoxypropan-1-amine
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C17H20N2O4
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1
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| 1 |
Ki = 1400 nM
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CP0457060
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1-(4-Benzyl-piperidin-1-yl)-3-(naphthalen-1-yloxy)-propan-2-ol
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C25H29NO2
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1
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| 1 |
Ki = 1438 nM
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CP0396197
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(2S,3S)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 1445.44 nM
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CP0398322
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4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-3H-pyridin-2-one
Show/Hide
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C24H26F3N5OS
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1
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| 1 |
Ki = 1445.44 nM
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CP0420656
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(2R,3S)-5-[3-[[4-methyl-5-(2-methylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C25H28F3N5S
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1
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| 1 |
Ki = 1479.11 nM
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CP0348498
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6-Amino-5,6,7,8-tetrahydro-naphthalen-1-ol
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C10H13NO
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1
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| 1 |
Ki = 1492 nM
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CP0110876
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N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
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C18H20ClN3O
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1
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| 1 |
Ki = 1500 nM
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CP0565597
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(2R,3S)-5-[3-[(4-methyl-5-pyridazin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 1548.82 nM
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CP0404659
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1-(4-methoxyphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H29N7OS
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1
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| 1 |
Ki = 1584.89 nM
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CP0465124
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4-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-oxazole
Show/Hide
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C23H26F3N5OS
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1
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| 1 |
Ki = 1584.89 nM
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CP0482523
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2-(benzenesulfonyl)-4-(4-cyclobutylpiperazin-1-yl)-1,3-dihydroisoindole
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C22H27N3O2S
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1
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| 1 |
Ki = 1592 nM
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CP0476094
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4-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]-1,3-thiazole
Show/Hide
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C23H26F3N5S2
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1
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| 1 |
Ki = 1621.81 nM
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CP0399464
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1-methyl-4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]piperidin-2-one
Show/Hide
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C25H32F3N5OS
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1
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| 1 |
Ki = 1698.24 nM
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CP0445693
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1-[[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-1,2,4-triazol-3-yl]sulfanyl]-3-[(2S,3R)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propan-2-ol
Show/Hide
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C23H26F3N5O2S
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1
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| 1 |
Ki = 1737.8 nM
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CP0507044
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(2S,3S)-5-[3-[(4-methyl-5-pyridazin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 1778.28 nM
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CP0390671
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2-(benzenesulfonyl)-4-(1-cyclobutylpiperidin-4-yl)-1,3-dihydroisoindole
Show/Hide
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C23H28N2O2S
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1
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| 1 |
Ki = 1826 nM
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CP0311650
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N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
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C19H23N3O2
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1
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| 1 |
Ki = 1880 nM
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CP0098943
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N-[2-(4-methoxyphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
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C18H23NO3
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1
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| 1 |
Ki = 1950 nM
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CP0510210
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
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C21H26N4O3S
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1
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| 1 |
Ki = 2000 nM
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CP0405530
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N-propyl-N-(4,5,6,7-tetrahydro-1-benzothiophen-5-ylmethyl)propan-1-amine
Show/Hide
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C15H25NS
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1
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| 1 |
Ki = 2037 nM
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CP0465122
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5-[5-[3-[(2R,3R)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C23H25F4N5OS
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1
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| 1 |
Ki = 2187.76 nM
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CP0398327
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1-methyl-4-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridin-2-one
Show/Hide
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C25H28F3N5OS
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1
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| 1 |
Ki = 2238.72 nM
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CP0424568
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(5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-naphthalene-1-carboxylic acid methyl ester
Show/Hide
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C16H23NO2
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1
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| 1 |
Ki = 2328 nM
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CP0467603
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1-(Naphthalen-1-yloxy)-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol
Show/Hide
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C24H27NO3
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1
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| 1 |
Ki = 2336 nM
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CP0418838
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N-[4-[2-(dipropylamino)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
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C18H32N4
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1
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| 1 |
Ki = 2400 nM
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CP0374678
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3-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
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C18H19Cl2N3O
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1
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| 1 |
Ki = 2420 nM
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CP0899499
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6-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
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C19H28N6S
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1
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| 1 |
Ki = 2511.89 nM
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CP0494145
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[(5S,6R)-5-methyl-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-yl] trifluoromethanesulfonate
Show/Hide
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C15H20F3NO3S
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1
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| 1 |
Ki = 2557 nM
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CP0396202
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(2S,3S)-5-[3-[(4-methyl-5-pyridazin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane
Show/Hide
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C23H25F3N6S
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1
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| 1 |
Ki = 2570.4 nM
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CP0958935
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6-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine
Show/Hide
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C19H29N7S
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1
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| 1 |
Ki = 2754.23 nM
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CP0429011
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3-(4-Chloro-benzyl)-8-hydroxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
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C19H16ClNO3
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1
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| 1 |
Ki = 2780 nM
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CP0431124
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N-propyl-N-(4,5,6,7-tetrahydro-1-benzothiophen-6-ylmethyl)propan-1-amine
Show/Hide
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C15H25NS
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1
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| 1 |
Ki = 3107 nM
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CP0404660
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1-(2-methylphenyl)-5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C23H29N7S
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1
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| 1 |
Ki = 3162.28 nM
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CP0405625
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((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
Show/Hide
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C14H21NO
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1
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| 1 |
Ki = 3206 nM
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CP0396203
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(2R,3S)-5-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-phenyl-5-azaspiro[2.4]heptane
Show/Hide
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C23H27N5S
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1
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| 1 |
Ki = 3311.31 nM
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CP0310814
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(S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol
Show/Hide
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C18H22F2N4O
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1
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| 1 |
Ki = 3346 nM
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CP0447814
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((S)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
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C17H27NO
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1
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| 1 |
Ki = 3351 nM
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CP0504193
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4-(2-Thiophen-2-yl-ethyl)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
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C18H21NO2S
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1
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| 1 |
Ki = 3676 nM
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CP0375155
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8-Methoxy-3-(4-trifluoromethyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
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C21H18F3NO3
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1
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| 1 |
Ki = 3700 nM
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CP0159532
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
Show/Hide
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C20H22N4O
|
1
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| 1 |
Ki = 3740 nM
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CP0465125
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5-[5-[3-[(2R,3S)-2-[4-fluoro-2-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
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C23H25F4N5OS
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1
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| 1 |
Ki = 3801.89 nM
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CP0409707
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(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
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C17H27NO
|
2
|
| 1 |
Ki = 3940 nM
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| 2 |
Ki > 10000 nM
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CP0141757
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
|
C19H20N4O
|
1
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| 1 |
Ki = 4180 nM
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CP0374756
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N-[4-[2-(4-pyridin-4-ylpiperazin-1-yl)ethyl]cyclohexyl]pyrimidin-2-amine
Show/Hide
|
C21H30N6
|
1
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| 1 |
Ki = 4800 nM
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CP0921608
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N-[4-(4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-6-yl)butyl]adamantane-1-carboxamide
Show/Hide
|
C22H33N3OS
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1
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| 1 |
Ki = 5495.41 nM
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CP0449041
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3-(3-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H18ClNO3
|
1
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| 1 |
Ki = 5500 nM
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CP0077364
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3-(4-bromophenoxy)-N-[2-(4-methylphenoxy)ethyl]propan-1-amine
Show/Hide
|
C18H22BrNO2
|
1
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| 1 |
Ki = 5730 nM
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CP0297070
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7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine
Show/Hide
|
C11H15NO
|
1
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| 1 |
Ki = 5825 nM
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CP0419743
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((R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
Show/Hide
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C17H27NO
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1
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| 1 |
Ki = 5882 nM
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CP0403294
|
5-[3-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1-[4-(trifluoromethyl)phenyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole
Show/Hide
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C25H34F3N5S
|
1
|
| 1 |
Ki = 6309.57 nM
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CP0468308
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4-[5-[3-[(4-methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Show/Hide
|
C23H26N8S
|
1
|
| 1 |
Ki = 6309.57 nM
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CP0962520
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6-[4-(4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-6-yl)butyl]-4,5,7,8-tetrahydrothiazolo[4,5-d]azepine
Show/Hide
|
C18H26N4S2
|
1
|
| 1 |
Ki = 6309.57 nM
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CP0548414
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
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C24H26N4O3S
|
1
|
| 1 |
Ki = 7200 nM
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CP0468740
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6-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxylic acid
Show/Hide
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C26H28F3N5O2S
|
1
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| 1 |
Ki = 7585.78 nM
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CP0405332
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(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki > 10000 nM
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CP0453517
|
(cis)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki > 10000 nM
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CP0395877
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
|
C20H22Cl2N4O3S
|
1
|
| 1 |
Ki > 10000 nM
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CP0395878
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H25FN4O3S2
|
1
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| 1 |
Ki > 10000 nM
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CP0447126
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
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C21H23N5O3S2
|
1
|
| 1 |
Ki > 10000 nM
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CP0497341
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C24H25ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
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CP0510213
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C20H22ClFN4O3S
|
1
|
| 1 |
Ki > 10000 nM
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CP0877516
|
phenyl-[4-[2-(4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-6-yl)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C20H26N4OS
|
1
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| 1 |
Ki = 41686.94 nM
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CP0401217
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((R)-7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine
Show/Hide
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C14H21NO
|
1
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| 1 |
Ki = 58882 nM
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CP0095655
|
(R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide
Show/Hide
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C16H23BrN2O3
|
1
|
| 1 |
Ki > 217 nM
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CP0258196
|
(+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol
Show/Hide
|
C16H25NO2
|
1
|
| 1 |
Ki > 217 nM
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CP0285377
|
(3aS,9bR)-6-methoxy-3-prop-2-enyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indole
Show/Hide
|
C16H21NO
|
2
|
| 1 |
Ki > 217 nM
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| 2 |
Ki > 339 nM
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CP0374707
|
[3-[(3S)-1-ethylpiperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
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C14H18F3NO3S
|
1
|
| 1 |
Ki > 217 nM
|
|
|
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CP0377339
|
1-[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-ethanone
Show/Hide
|
C16H23NO
|
2
|
| 1 |
Ki > 217 nM
|
|
|
| 2 |
Ki > 1852 nM
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CP0377497
|
[(3aS,9bR)-3-prop-2-enyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-6-yl] trifluoromethanesulfonate
Show/Hide
|
C16H18F3NO3S
|
1
|
| 1 |
Ki > 217 nM
|
|
|
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CP0383244
|
(S)-1-Propyl-3-m-tolyl-piperidine
Show/Hide
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C15H23N
|
1
|
| 1 |
Ki > 217 nM
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|
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CP0395196
|
(S)-3-Phenyl-1-propyl-piperidine
Show/Hide
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C14H21N
|
1
|
| 1 |
Ki > 217 nM
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|
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CP0398217
|
[3-[(3S)-1-methylpiperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
|
C13H16F3NO3S
|
1
|
| 1 |
Ki > 217 nM
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CP0398227
|
[2-[(3S)-1-propylpiperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
|
C15H20F3NO3S
|
1
|
| 1 |
Ki > 217 nM
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|
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CP0398241
|
(3-propyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-6-yl) trifluoromethanesulfonate
Show/Hide
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C16H20F3NO3S
|
1
|
| 1 |
Ki > 217 nM
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|
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CP0403548
|
(S)-3-(3-Ethynyl-phenyl)-1-propyl-piperidine
Show/Hide
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C16H21N
|
1
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| 1 |
Ki > 217 nM
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CP0403905
|
[3-[(3S)-1-propylpiperidin-3-yl]phenyl] 4-methylbenzenesulfonate
Show/Hide
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C21H27NO3S
|
1
|
| 1 |
Ki > 217 nM
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|
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CP0422896
|
3-((S)-1-Propyl-piperidin-3-yl)-benzamide
Show/Hide
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C15H22N2O
|
2
|
| 1 |
Ki > 217 nM
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|
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| 2 |
Ki > 1852 nM
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CP0433176
|
3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carboxylic acid amide
Show/Hide
|
C16H20N2O
|
2
|
| 1 |
Ki > 217 nM
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| 2 |
Ki > 1500 nM
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CP0440419
|
3-((S)-1-Propyl-piperidin-3-yl)-benzoic acid methyl ester
Show/Hide
|
C16H23NO2
|
2
|
| 1 |
Ki > 217 nM
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| 2 |
Ki > 1852 nM
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|
CP0448508
|
3-((S)-1-Propyl-piperidin-3-yl)-phenylamine
Show/Hide
|
C14H22N2
|
1
|
| 1 |
Ki > 217 nM
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|
|
|
CP0448598
|
(S)-1-Propyl-3-(3-propyl-phenyl)-piperidine
Show/Hide
|
C17H27N
|
1
|
| 1 |
Ki > 217 nM
|
|
|
|
CP0454451
|
(S)-3-(3-Methylsulfanyl-phenyl)-1-propyl-piperidine
Show/Hide
|
C15H23NS
|
1
|
| 1 |
Ki > 217 nM
|
|
|
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CP0460417
|
[4-[(3S)-1-propylpiperidin-3-yl]-2-(trifluoromethylsulfonyloxy)phenyl] trifluoromethanesulfonate
Show/Hide
|
C16H19F6NO6S2
|
1
|
| 1 |
Ki > 217 nM
|
|
|
|
CP0460496
|
C,C,C-Trifluoro-N-[3-((S)-1-propyl-piperidin-3-yl)-phenyl]-methanesulfonamide
Show/Hide
|
C15H21F3N2O2S
|
1
|
| 1 |
Ki > 217 nM
|
|
|
|
CP0478351
|
(3-prop-2-enyl-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-6-yl) trifluoromethanesulfonate
Show/Hide
|
C16H18F3NO3S
|
1
|
| 1 |
Ki > 217 nM
|
|
|
|
CP0496401
|
(4-propyl-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-7-yl) trifluoromethanesulfonate
Show/Hide
|
C17H22F3NO3S
|
1
|
| 1 |
Ki > 217 nM
|
|
|
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CP0511132
|
3-((S)-1-Butyl-piperidin-3-yl)-benzonitrile
Show/Hide
|
C16H22N2
|
1
|
| 1 |
Ki > 217 nM
|
|
|
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CP0535152
|
[4-[(3S)-1-propylpiperidin-3-yl]phenyl] trifluoromethanesulfonate
Show/Hide
|
C15H20F3NO3S
|
1
|
| 1 |
Ki > 217 nM
|
|
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CP0190867
|
(E)-3-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-(4-methoxy-benzyl)-acrylamide
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0443105
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C22H23FN4O3S2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0447217
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]thiophene-2-sulfonamide
Show/Hide
|
C20H24FN3O3S2
|
1
|
| 1 |
Ki > 1000 nM
|
|
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|
CP0489950
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C23H26FN5O3S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0887498
|
US8952128, 21
Show/Hide
|
C86H110N18O13S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0960071
|
US8952128, 19
Show/Hide
|
C87H110FN17O13S
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0378668
|
(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyrimidin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C19H21ClF2N4O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421427
|
US10562853, Compound 63
Show/Hide
|
C22H25ClF2N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421429
|
US10562853, Compound 3
Show/Hide
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C23H26Cl2FN3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421456
|
US10562853, Compound 64
Show/Hide
|
C21H22ClF3N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421480
|
(3,4-dichlorophenyl)-[4-fluoro-4-[[2-(3-fluorophenoxy)ethylamino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C21H22Cl2F2N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0424643
|
US10562853, Compound 9
Show/Hide
|
C22H25Cl2FN2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0432123
|
(3-chloro-4-fluorophenyl)-[4-[[2-(2,3-dihydro-1H-indol-4-yloxy)ethylamino]methyl]-4-fluoropiperidin-1-yl]methanone
Show/Hide
|
C23H26ClF2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0432139
|
US10562853, Compound 62
Show/Hide
|
C21H22Cl2F2N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0448031
|
US10562853, Compound 10
Show/Hide
|
C22H25ClF2N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0471528
|
US10562853, Compound 45
Show/Hide
|
C23H28ClF2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0471529
|
US10562853, Compound 2
Show/Hide
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C23H26ClF2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0471679
|
US10562853, Compound 46
Show/Hide
|
C22H22ClF5N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0471680
|
US10562853, Compound 1
Show/Hide
|
C21H23ClF2N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479915
|
US10562853, Compound 44
Show/Hide
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C23H24ClF2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479916
|
US10562853, Compound 52
Show/Hide
|
C22H26ClF2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479918
|
US10562853, Compound 61
Show/Hide
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C21H22ClF3N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479919
|
US10562853, Compound 11
Show/Hide
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C22H25Cl2FN2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479920
|
US10562853, Compound 47
Show/Hide
|
C22H24ClF2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479922
|
US10562853, Compound 16
Show/Hide
|
C24H24ClF2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479927
|
US10562853, Compound 65
Show/Hide
|
C21H22Cl2F2N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479949
|
US10562853, Compound 8
Show/Hide
|
C22H25ClF2N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479950
|
US10562853, Compound 4
Show/Hide
|
C21H22Cl2F2N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479951
|
US10562853, Compound 5
Show/Hide
|
C21H22ClF3N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0479952
|
US10562853, Compound 51
Show/Hide
|
C22H26ClF2N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0484979
|
US10562853, Compound 48
Show/Hide
|
C22H24ClF2N3O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0552411
|
[4-[[2-(3-chlorophenoxy)ethylamino]methyl]-4-fluoropiperidin-1-yl]-(3,4-dichlorophenyl)methanone
Show/Hide
|
C21H22Cl3FN2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0552412
|
US10562853, Compound 14
Show/Hide
|
C23H25ClF2N2O4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0777252
|
2-Iodo-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
Show/Hide
|
C20H22IN3O2S
|
1
|
| 1 |
Ki > 2000 nM
|
|
|
|
CP0860616
|
3-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
Show/Hide
|
C20H22ClN3O2S
|
1
|
| 1 |
Ki > 2000 nM
|
|
|
|
CP0873359
|
2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
Show/Hide
|
C20H22ClN3O2S
|
1
|
| 1 |
Ki > 2000 nM
|
|
|
|
CP0376224
|
1-(2-Fluoro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
Show/Hide
|
C19H17FN2O2S
|
1
|
| 1 |
Ki > 2000 nM
|
|
|
|
CP0409239
|
1-(2-Chloro-benzenesulfonyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole
Show/Hide
|
C19H17ClN2O2S
|
1
|
| 1 |
Ki > 2000 nM
|
|
|
|
CP0416596
|
4-Phenethyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol
Show/Hide
|
C20H23NO2
|
1
|
| 1 |
Ki > 3676 nM
|
|
|
|
CP0465298
|
4,5a,6,7,8,9a-Hexahydro-5H-9-oxa-3-thia-6-aza-cyclopenta[a]naphthalene
Show/Hide
|
C10H13NOS
|
1
|
| 1 |
Ki > 4780 nM
|
|
|
|
CP0266526
|
(R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol
Show/Hide
|
C18H22F2N4O
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0853639
|
2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
Show/Hide
|
C19H20ClN3O2S
|
1
|
| 1 |
Ki > 5000 nM
|
|
|
|
CP0393313
|
8-Methoxy-3-(4-methoxy-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H21NO4
|
1
|
| 1 |
Ki > 5800 nM
|
|
|
|
CP0405629
|
3-(2-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H18ClNO3
|
1
|
| 1 |
Ki > 5800 nM
|
|
|
|
CP0406449
|
3-(4-Chloro-benzyl)-8,9-dimethoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C21H20ClNO4
|
1
|
| 1 |
Ki > 5800 nM
|
|
|
|
CP0409709
|
3-(4-Chloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H18ClNO3
|
1
|
| 1 |
Ki > 5800 nM
|
|
|
|
CP0419228
|
3-(3,4-Dichloro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H17Cl2NO3
|
1
|
| 1 |
Ki > 5800 nM
|
|
|
|
CP0424524
|
8-Methoxy-3-(4-nitro-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
Show/Hide
|
C20H18N2O5
|
1
|
| 1 |
Ki > 5800 nM
|
|
|
|
CP0424527
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8-Methoxy-3-pyridin-4-ylmethyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C19H18N2O3
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1
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| 1 |
Ki > 5800 nM
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CP0432916
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8-Methoxy-3-phenethyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C21H21NO3
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1
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| 1 |
Ki > 5800 nM
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CP0439261
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3-(4-Fluoro-benzyl)-8-methyl-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C20H18FNO2
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1
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| 1 |
Ki > 5800 nM
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CP0448817
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3-(4-Fluoro-benzyl)-8-methoxy-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one
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C20H18FNO3
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1
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| 1 |
Ki > 5800 nM
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CP0159468
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3-(4-bromophenoxy)-N-[2-(4-chlorophenoxy)ethyl]propan-1-amine
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C17H19BrClNO2
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1
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| 1 |
Ki > 5880 nM
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