Brief Information of the Compound and Protein
Compound Name
4-(4-chlorophenyl)-1-[3-(4-fluorophenoxy)propyl]piperidin-4-ol
    Show/Hide
PubChem ID
CID: 21527771
Canonical SMILES
OC1(CCN(CCCOc2ccc(F)cc2)CC1)c1ccc(Cl)cc1
    Show/Hide
Compound Formula C20H23ClFNO2
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
Kd = 0.7943 nM
   TI
   LI
   LO
   TS
2
Ki = 1.072 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.3 nM
2 Ki = 8.8 nM