Brief Information of the Compound and Protein
Compound Name
(-)-Tetrahydropalmatine
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PubChem ID
CID: 72301
SID: 16014105
Canonical SMILES
COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(OC)c4OC
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Compound Formula C21H25NO4
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 5000 nM
   TI
   LI
   LO
   TS