Brief Information of the Compound and Protein
| Compound Name |
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
D(2) dopamine receptor
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Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
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| Uniprot ID | Gene Name | DRD2 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 10 nM | ||
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| 2 | Ki = 2.1 nM | ||
| 3 | Ki = 11 nM | ||
| 4 | Ki = 17 nM | ||
| 5 | Ki = 20 nM | ||
| 6 | Ki = 31 nM | ||
| 7 | Ki = 58 nM | ||
| 8 | Ki = 78 nM | ||
| 9 | Ki = 100 nM | ||