Brief Information of the Compound and Protein
Compound Name
(4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-pyrimidin-2-yl-amine
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PubChem ID
SID: 15775030
Canonical SMILES
Fc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)Nc2ncccn2)CC1
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Compound Formula C22H30FN5
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 79 nM
   TI
   LI
   LO
   TS
2
Ki = 8.5 nM
   TI
   LI
   LO
   TS