Brief Information of the Compound and Protein
Compound Name
3-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)propan-1-one
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PubChem ID
CID: 21390740
Canonical SMILES
CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)c2cc(Cl)cc(Cl)c2)c(F)c1
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Compound Formula C23H26Cl2FN3O3S
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
Kd = 144.54 nM
   TI
   LI
   LO
   TS
2
Ki = 131.83 nM
   TI
   LI
   LO
   TS