General Information of the Compound
Compound ID
CP0429443
Compound Name
1-(benzenesulfonyl)-4-[4-(3-phenoxypropyl)piperazin-1-yl]indole
    Show/Hide
Structure
Formula
C27H29N3O3S
Molecular Weight
475.614
Canonical SMILES
O=S(=O)(c1ccccc1)n1ccc2c(cccc12)N1CCN(CCCOc2ccccc2)CC1
    Show/Hide
InChI
InChI=1S/C27H29N3O3S/c31-34(32,24-11-5-2-6-12-24)30-17-15-25-26(13-7-14-27(25)30)29-20-18-28(19-21-29)16-8-22-33-23-9-3-1-4-10-23/h1-7,9-15,17H,8,16,18-22H2
    Show/Hide
InChIKey
VESLKGGUOOCKRO-UHFFFAOYSA-N
Physicochemical Property
logP
4.4694
Rotatable Bonds
8
Heavy Atom Count
34
Polar Areas
54.78
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 71502631
SID: 163487349
ChEMBL ID
CHEMBL3409260
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 7.6 nM
   TI
   LI
   LO
   TS
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 290 nM
   TI
   LI
   LO
   TS