General Information of the Compound
| Compound ID |
CP0468740
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| Compound Name |
6-methyl-5-[4-methyl-5-[3-[(2R,3S)-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptan-5-yl]propylsulfanyl]-1,2,4-triazol-3-yl]pyridine-2-carboxylic acid
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| Structure |
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| Formula |
C26H28F3N5O2S
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| Molecular Weight |
531.604
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| Canonical SMILES |
Cc1nc(ccc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)n1C)C(O)=O
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| InChI |
InChI=1S/C26H28F3N5O2S/c1-16-19(8-9-21(30-16)23(35)36)22-31-32-24(33(22)2)37-13-3-11-34-12-10-25(15-34)14-20(25)17-4-6-18(7-5-17)26(27,28)29/h4-9,20H,3,10-15H2,1-2H3,(H,35,36)/t20-,25+/m1/s1
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| InChIKey |
FXIOLEMXUYMYEG-NLFFAJNJSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Protein ID: PT00943, D(3) dopamine receptor
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2