General Information of the Compound
Compound ID
CP0930839
Compound Name
US8952128, 39
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Structure
Formula
C96H123FN18O9S2
Molecular Weight
1756.289
Canonical SMILES
C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N(CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCSC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)CCCCNC(=O)[C@H](Cc2ccc(F)cc2)NC1=O
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InChI
InChI=1S/C96H123FN18O9S2/c1-58(116)87-95(124)111-78(47-61-32-34-67(97)35-33-61)88(117)101-37-15-13-31-82(115(39-41-125-56-62-43-71-69-24-16-28-74-85(69)65(52-104-74)49-83(71)113(2)54-62)40-42-126-57-63-44-72-70-25-17-29-75-86(70)66(53-105-75)50-84(72)114(3)55-63)94(123)107-77(30-18-38-102-96(99)100)89(118)108-79(45-59-19-6-4-7-20-59)91(120)109-80(46-60-21-8-5-9-22-60)92(121)110-81(48-64-51-103-73-26-11-10-23-68(64)73)93(122)106-76(90(119)112-87)27-12-14-36-98/h4-11,16-17,19-26,28-29,32-35,51-53,58,62-63,71-72,76-84,87,103-105,116H,12-15,18,27,30-31,36-50,54-57,98H2,1-3H3,(H,101,117)(H,106,122)(H,107,123)(H,108,118)(H,109,120)(H,110,121)(H,111,124)(H,112,119)(H4,99,100,102)/t58-,62-,63-,71-,72-,76+,77+,78+,79+,80+,81-,82-,83-,84-,87+/m1/s1
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InChIKey
QUQFXVLPNVKYNB-QXRKNLDISA-N
Physicochemical Property
logP
7.46437
Rotatable Bonds
28
Heavy Atom Count
126
Polar Areas
398.04
Hydrogen Bond Donor Count
16
Hydrogen Bond Acceptor Count
16
Complexity
126

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 91809315
ChEMBL ID
CHEMBL3647714
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 329.7 nM
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   LI
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