Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
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 PubChem ID
CID: 137646281
Canonical SMILES
COc1ccccc1N1CCN(CCCSc2nnc(-c3ccccc3)n2C)CC1
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Compound Formula C23H29N5OS
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 254 nM
   TI
   LI
   LO
   TS
2
IC50 = 328.3 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 260 nM
   TI
   LI
   LO
   TS