| Compound ID |
Compound Name |
Compound Formula |
|
CP0527522
|
4-(4-cyanophenyl)-N-quinolin-2-ylbenzenesulfonamide
Show/Hide
|
C22H15N3O2S
|
1
|
| 1 |
EC50 = 0.03 nM
|
|
|
|
CP0515388
|
3-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptyl-N-cyclopropylbenzamide
Show/Hide
|
C25H28ClN3O4S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0415760
|
3-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cyclohexyl-N-cyclopropylbenzamide
Show/Hide
|
C24H26ClN3O4S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0426196
|
N-(2-adamantyl)-3-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-methylbenzamide
Show/Hide
|
C26H28ClN3O4S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0522510
|
3-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptyl-N-methylbenzamide
Show/Hide
|
C23H26ClN3O4S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0070242
|
N-(Pyridin-2-yl) arylsulfonamide, 26
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|
C18H14N4O2S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0276378
|
N-(Pyridin-2-yl) arylsulfonamide, 25
Show/Hide
|
C21H19N3O2S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0316854
|
N-(Pyridin-2-yl) arylsulfonamide, 28
Show/Hide
|
C20H18N4O2S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0099120
|
(3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
Show/Hide
|
C42H62O16
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0428445
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptyl-N-methylpiperidine-1-carboxamide
Show/Hide
|
C22H31ClN4O4S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0486469
|
4-(4-cyanophenyl)-N-(4,6-dimethylpyridin-2-yl)benzenesulfonamide
Show/Hide
|
C20H17N3O2S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0145647
|
N-(Pyridin-2-yl) arylsulfonamide, 23
Show/Hide
|
C20H17N3O2S
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0208823
|
N-(Pyridin-2-yl) arylsulfonamide, 22
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|
C19H15N3O2S
|
2
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
EC50 = 53 nM
|
|
|
|
CP0428443
|
N-(1-adamantyl)-4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]benzamide
Show/Hide
|
C25H26ClN3O4S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0527521
|
N-(6-amino-4-methylpyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide
Show/Hide
|
C19H16N4O2S
|
1
|
| 1 |
EC50 = 49 nM
|
|
|
|
CP0191830
|
N-(Pyridin-2-yl) arylsulfonamide, 24
Show/Hide
|
C21H17N3O2S
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0555795
|
4-(4-cyanophenyl)-N-[6-[(1R)-1-hydroxypropyl]pyridin-2-yl]benzenesulfonamide
Show/Hide
|
C21H19N3O3S
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0428442
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptyl-N-cyclopropylbenzamide
Show/Hide
|
C25H28ClN3O4S
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0525314
|
4-(4-cyanophenyl)-N-[6-(hydroxymethyl)pyridin-2-yl]benzenesulfonamide
Show/Hide
|
C19H15N3O3S
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0426200
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cyclohexyl-N-cyclopropylbenzamide
Show/Hide
|
C24H26ClN3O4S
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0428439
|
N-(1-adamantyl)-4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-methylbenzamide
Show/Hide
|
C26H28ClN3O4S
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0511057
|
4-(4-cyanophenyl)-N-(1,5-naphthyridin-2-yl)benzenesulfonamide
Show/Hide
|
C21H14N4O2S
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
|
CP0515387
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptyl-N-methylbenzamide
Show/Hide
|
C23H26ClN3O4S
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0428842
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cyclohexyl-N-cyclopropylpiperidine-1-carboxamide
Show/Hide
|
C23H31ClN4O4S
|
1
|
| 1 |
EC50 = 121 nM
|
|
|
|
CP0428441
|
N-(2-adamantyl)-4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-methylpiperidine-1-carboxamide
Show/Hide
|
C25H33ClN4O4S
|
1
|
| 1 |
EC50 = 158 nM
|
|
|
|
CP0316853
|
N-(Pyridin-2-yl) arylsulfonamide, 27
Show/Hide
|
C19H16N4O2S
|
1
|
| 1 |
EC50 = 184 nM
|
|
|
|
CP0560899
|
4-(4-cyanophenyl)-N-[6-[(1R)-1-hydroxyethyl]pyridin-2-yl]benzenesulfonamide
Show/Hide
|
C20H17N3O3S
|
1
|
| 1 |
EC50 = 184 nM
|
|
|
|
CP0527635
|
4-(4-cyanophenyl)-N-(5-fluoro-6-methylpyridin-2-yl)benzenesulfonamide
Show/Hide
|
C19H14FN3O2S
|
1
|
| 1 |
EC50 = 194 nM
|
|
|
|
CP0489410
|
4-(4-cyanophenyl)-N-(5,6-dimethylpyridin-2-yl)benzenesulfonamide
Show/Hide
|
C20H17N3O2S
|
1
|
| 1 |
EC50 = 213 nM
|
|
|
|
CP0428440
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptylpiperidine-1-carboxamide
Show/Hide
|
C21H29ClN4O4S
|
1
|
| 1 |
EC50 = 283 nM
|
|
|
|
CP0850956
|
rac-4'-cyano-N-(6-(1-hydroxyethyl)pyridin-2-yl)biphenyl-4-sulfonamide
Show/Hide
|
C20H17N3O3S
|
1
|
| 1 |
EC50 = 327 nM
|
|
|
|
CP0524068
|
4-(4-cyanophenyl)-N-[6-(2-hydroxyethyl)pyridin-2-yl]benzenesulfonamide
Show/Hide
|
C20H17N3O3S
|
1
|
| 1 |
EC50 = 423 nM
|
|
|
|
CP0426199
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cyclooctylbenzamide
Show/Hide
|
C23H26ClN3O4S
|
1
|
| 1 |
EC50 = 443 nM
|
|
|
|
CP0428444
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptyl-N-cyclopropylpiperidine-1-carboxamide
Show/Hide
|
C24H33ClN4O4S
|
1
|
| 1 |
EC50 = 517 nM
|
|
|
|
CP0560898
|
4-(4-cyanophenyl)-N-pyridin-2-ylbenzenesulfonamide
Show/Hide
|
C18H13N3O2S
|
1
|
| 1 |
EC50 = 604 nM
|
|
|
|
CP0426198
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cyclohexylbenzamide
Show/Hide
|
C21H22ClN3O4S
|
1
|
| 1 |
EC50 = 686 nM
|
|
|
|
CP0513741
|
4-[(7-chloro-1,1,3-trioxo-4H-1lambda6,2,4-benzothiadiazin-2-yl)methyl]-N-cycloheptylbenzamide
Show/Hide
|
C22H24ClN3O4S
|
1
|
| 1 |
EC50 = 802 nM
|
|
|
|
CP0807468
|
4'-cyano-N-(6-(dimethylamino)pyridin-2-yl)biphenyl-4-sulfonamide
Show/Hide
|
C20H18N4O2S
|
1
|
| 1 |
EC50 = 846 nM
|
|
|
|
CP0538019
|
4-(4-cyanophenyl)-N-[6-[(1S)-1-hydroxypropyl]pyridin-2-yl]benzenesulfonamide
Show/Hide
|
C21H19N3O3S
|
1
|
| 1 |
EC50 = 936 nM
|
|
|
|
CP0527520
|
4-(4-cyanophenyl)-N-[6-[(1S)-1-hydroxyethyl]pyridin-2-yl]benzenesulfonamide
Show/Hide
|
C20H17N3O3S
|
1
|
| 1 |
EC50 = 1161 nM
|
|
|
|
CP0525315
|
4-(4-cyanophenyl)-N-(3-fluoro-6-methylpyridin-2-yl)benzenesulfonamide
Show/Hide
|
C19H14FN3O2S
|
1
|
| 1 |
EC50 = 1980 nM
|
|
|
|
CP0527523
|
4-(4-cyanophenyl)-N-(3-methoxy-6-methylpyridin-2-yl)benzenesulfonamide
Show/Hide
|
C20H17N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0062088
|
(2R)-N-(adamantan-2-yl)-1-[(4-cyanophenyl)methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 0.03 nM
|
|
|
|
CP0062228
|
(2R)-N-(adamantan-2-yl)-1-(2-methylpropyl)pyrrolidine-2-carboxamide
Show/Hide
|
C19H32N2O
|
1
|
| 1 |
IC50 = 0.03 nM
|
|
|
|
CP0239999
|
(2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclohexyl)methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C22H36N2O2
|
1
|
| 1 |
IC50 = 0.03 nM
|
|
|
|
CP0333803
|
(2R)-N-(adamantan-2-yl)-1-(cyclopentylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C21H34N2O
|
1
|
| 1 |
IC50 = 0.03 nM
|
|
|
|
CP0333804
|
(2R)-N-(adamantan-2-yl)-1-(cyclobutylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C20H32N2O
|
1
|
| 1 |
IC50 = 0.03 nM
|
|
|
|
CP0062229
|
(2R)-N-(adamantan-2-yl)-1-(cyclohexylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C22H36N2O
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0128628
|
(2R)-N-(adamantan-2-yl)-1-[(3-cyanophenyl)methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0224913
|
(2R)-N-(adamantan-2-yl)-1-[(4-chlorophenyl)methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C22H29ClN2O
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0277565
|
(2R)-N-(adamantan-2-yl)-1-(2,2,2-trifluoroethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C17H25F3N2O
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0289367
|
(2R)-N-(adamantan-2-yl)-1-(3,3,3-trifluoropropyl)pyrrolidine-2-carboxamide
Show/Hide
|
C18H27F3N2O
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0128626
|
(2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclopentyl)methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C21H34N2O2
|
1
|
| 1 |
IC50 = 0.34 nM
|
|
|
|
CP0576026
|
3-[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]-3-methylbutan-1-ol
Show/Hide
|
C20H22ClN3O
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0455881
|
N-{4-[(1-cyanocyclopropyl)methyl]cyclohexyl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H29F3N2O2
|
2
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
|
CP0300917
|
(2R)-N-(adamantan-2-yl)-1-propylpyrrolidine-2-carboxamide
Show/Hide
|
C18H30N2O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0138426
|
N-[4-(2-cyanoethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C22H27F3N2O2
|
3
|
| 1 |
IC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
| 3 |
IC50 = 11 nM
|
|
|
|
CP0218947
|
(S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-Nethylbenzamide
Show/Hide
|
C18H24F3NO2
|
2
|
| 1 |
IC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
|
CP0422749
|
N-[4-(2-cyano-2,2-dimethylethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H31F3N2O2
|
2
|
| 1 |
IC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0527808
|
N-(5-hydroxy-2-adamantyl)-6-piperidin-1-ylpyridine-2-carboxamide
Show/Hide
|
C21H29N3O2
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0398275
|
N-cyclopropyl-N-(4-hydroxycyclohexyl)-6-piperidin-1-ylpyridine-2-carboxamide
Show/Hide
|
C20H29N3O2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0425913
|
N-(5-hydroxy-2-adamantyl)-6-[4-(hydroxymethyl)piperidin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C22H31N3O3
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0452572
|
4-[(3-Chlorophenylsulfonamido)methyl]-N-cycloheptyl-N-propylbenzamide
Show/Hide
|
C24H31ClN2O3S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0465974
|
1,1,1-trifluoro-2-(4-((S)-2-methylpiperidin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C15H20F3NO3S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0062226
|
N-(2-adamantyl)-2-[cyclohexyl(ethyl)amino]acetamide
Show/Hide
|
C20H34N2O
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0432946
|
2,5-dichloro-N-propan-2-yl-N-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl]benzenesulfonamide
Show/Hide
|
C18H18Cl2F3NO3S
|
2
|
| 1 |
IC50 = 2.2 nM
|
|
|
| 2 |
IC50 = 21 nM
|
|
|
|
CP0254866
|
BMS-823778
Show/Hide
|
C18H18ClN3O
|
2
|
| 1 |
IC50 = 2.3 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0040791
|
(S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylbenzamide
Show/Hide
|
C19H24F3NO2
|
2
|
| 1 |
IC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 38 nM
|
|
|
|
CP0296448
|
(S)-3'-cyclopropyl-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile
Show/Hide
|
C25H20F3NO3S
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0414130
|
CHEMBL3394400
Show/Hide
|
C22H28F3N3O3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0397873
|
3-cycloheptyl-8-[(3,5-dichlorophenyl)sulfanylmethyl]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C20H21Cl2N3S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0386769
|
6-[4-(4-cyanophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H31N5O2
|
2
|
| 1 |
IC50 = 2.8 nM
|
|
|
| 2 |
IC50 = 6.7 nM
|
|
|
|
CP0574752
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-2-methyl-4-[6-(methylcarbamoyl)pyridin-3-yl]piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C28H36N6O3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0132712
|
1-[(2-chlorophenyl)methoxy]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H15ClN2O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0323520
|
1-[(2-cyanopyridin-3-yl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H14N4OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0425912
|
N-(5-hydroxy-2-adamantyl)-6-[4-(4-hydroxyphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0524591
|
CHEMBL3401681
Show/Hide
|
C28H36N4O4S
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0514693
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-2-methyl-4-(4-methylsulfonylphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C28H36N4O4S
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0398274
|
N-(5-hydroxy-2-adamantyl)-6-(4-hydroxy-4-phenylpiperidin-1-yl)pyridine-2-carboxamide
Show/Hide
|
C27H33N3O3
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0400070
|
CHEMBL3394402
Show/Hide
|
C24H33N3O3
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0236512
|
(2R)-N-(adamantan-2-yl)-1-(propan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C18H30N2O
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0514694
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-4-[6-(2-hydroxypropan-2-yl)pyridin-3-yl]-2-methylpiperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C29H39N5O3
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0287484
|
3-(1-bicyclo[2.2.1]heptanyl)-8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C20H20ClN3O
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0218934
|
1-[(2-chloro-6-fluorophenyl)methyl]-4-naphthalen-2-ylsulfonyl-1,4-diazepane
Show/Hide
|
C22H22ClFN2O2S
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0398497
|
N-cyclopropyl-N-[4-hydroxy-4-(trifluoromethyl)cyclohexyl]-6-piperidin-1-ylpyridine-2-carboxamide
Show/Hide
|
C21H28F3N3O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0418666
|
N-(5-hydroxy-2-adamantyl)-6-(4-pyridin-2-ylpiperazin-1-yl)pyridine-2-carboxamide
Show/Hide
|
C25H31N5O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0577612
|
6-[(2R)-4-(6-carbamoylpyridin-3-yl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H34N6O3
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0400067
|
N-(5-hydroxy-2-adamantyl)-6-(4-phenylpiperazin-1-yl)pyridine-2-carboxamide
Show/Hide
|
C26H32N4O2
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0109469
|
N-[4-(3-amino-3-oxopropyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C28H33F3N2O3
|
2
|
| 1 |
IC50 = 3.9 nM
|
|
|
| 2 |
IC50 = 37 nM
|
|
|
|
CP0398496
|
CHEMBL3394401
Show/Hide
|
C22H31N3O3
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0418707
|
N-(5-hydroxy-2-adamantyl)-6-[4-(4-methylsulfonylphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C27H34N4O4S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0093369
|
1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H11ClN2OS
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0273842
|
1-[(2,6-dichlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H14Cl2N2OS
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0566935
|
(1R,7S)-1,3,10,10-tetramethyl-4-[[2-(trifluoromethyl)phenyl]methyl]-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C20H23F3N2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0411289
|
CHEMBL3394407
Show/Hide
|
C24H34N4O3
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0259117
|
(2R)-N-(adamantan-2-yl)-1-ethylpyrrolidine-2-carboxamide
Show/Hide
|
C17H28N2O
|
1
|
| 1 |
IC50 = 4.15 nM
|
|
|
|
CP0577986
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-2-methyl-4-[4-(methylsulfamoyl)phenyl]piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C28H37N5O4S
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0317450
|
2-[(2R)-4-(2-fluoro-4-methylsulfonylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C27H34FN5O4S
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0102242
|
((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamido)-1-phenylcyclohexyl)methyl carbamate
Show/Hide
|
C27H31F3N2O4
|
2
|
| 1 |
IC50 = 4.6 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0398260
|
CHEMBL3394396
Show/Hide
|
C21H31N3O2
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0514695
|
2-[(2R)-4-(4-ethylsulfonyl-2-fluorophenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C28H36FN5O4S
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0524592
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-4-[4-(2-hydroxypropan-2-yl)phenyl]-2-methylpiperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C30H40N4O3
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0455922
|
N-{4-[(1-carbamoylcyclopropyl)methyl]cyclohexyl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H31F3N2O3
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 90 nM
|
|
|
|
CP0270350
|
(2R)-N-(adamantan-2-yl)-1-(pyridin-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C20H27N3O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0237982
|
4-benzylsulfanyl-2-oxo-5,6-dihydro-3H-benzo[f]isoquinoline-1-carbonitrile
Show/Hide
|
C21H16N2OS
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0487003
|
6-[(2R)-4-(4-cyanophenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C28H33N5O2
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0253178
|
8-(3-chloro-2-methylphenoxy)-3-(1-methoxycycloheptyl)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0342276
|
8-(3-chloro-2-methylphenoxy)-3-(3-methoxy-1-adamantyl)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C24H26ClN3O2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0054284
|
((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamido)-1-(2-fluorophenyl)cyclohexyl)methyl carbamate
Show/Hide
|
C27H30F4N2O4
|
2
|
| 1 |
IC50 = 5.7 nM
|
|
|
| 2 |
IC50 = 135 nM
|
|
|
|
CP0128835
|
N-cyclopropyl-N-[4-(pyridin-3-yl)cyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H27F3N2O2
|
2
|
| 1 |
IC50 = 5.8 nM
|
|
|
| 2 |
IC50 = 124 nM
|
|
|
|
CP0234339
|
2-chloro-N-propan-2-yl-N-[4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl]benzenesulfonamide
Show/Hide
|
C18H19ClF3NO3S
|
2
|
| 1 |
IC50 = 5.8 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
|
CP0135040
|
[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]-cyclopropylmethanol
Show/Hide
|
C19H18ClN3O
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0093366
|
1-[(2-chlorophenyl)methylsulfanyl]-8-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H10ClFN2OS
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0556226
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-4-(4-methoxyphenyl)-2-methylpiperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C28H36N4O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0528351
|
N-[4-(2-carbamoyl-2,2-dimethylethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H33F3N2O3
|
2
|
| 1 |
IC50 = 6.1 nM
|
|
|
| 2 |
IC50 = 97 nM
|
|
|
|
CP0398273
|
N-cyclopropyl-N-(4-hydroxy-4-methylcyclohexyl)-6-piperidin-1-ylpyridine-2-carboxamide
Show/Hide
|
C21H31N3O2
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0204550
|
2-bromo-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H19BrF3NO3S
|
2
|
| 1 |
IC50 = 6.6 nM
|
|
|
| 2 |
IC50 = 86 nM
|
|
|
|
CP0398259
|
6-[4-(2-amino-2-oxoethyl)piperidin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C23H32N4O3
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0140347
|
N-[4-(acetamidomethyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C28H33F3N2O3
|
2
|
| 1 |
IC50 = 6.7 nM
|
|
|
| 2 |
IC50 = 129 nM
|
|
|
|
CP0541951
|
CHEMBL3394409
Show/Hide
|
C27H34N4O2
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0523318
|
N-(5-hydroxy-2-adamantyl)-6-[(2S)-2-methyl-4-(4-methylsulfonylphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C28H36N4O4S
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0172643
|
1-piperidin-1-yl-cyclopropanecarboxylic acid (5-hydroxy-adamantan-2-yl)-amide
Show/Hide
|
C19H30N2O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0080441
|
N-[4-(3-amino-3-oxopropyl)-4-(2-fluorophenyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C28H32F4N2O3
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
IC50 = 109 nM
|
|
|
|
CP0335644
|
1-[(2-cyanophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C18H15N3OS
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0262956
|
(1R,7S)-4-(2,5-dichlorophenyl)-1,3,10,10-tetramethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0556658
|
(1R,7S)-3-benzyl-4-(2-fluorophenyl)-1,10,10-trimethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C24H25FN2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0411288
|
N-(5-hydroxy-2-adamantyl)-6-[4-(pyridin-3-ylmethyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C26H33N5O2
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0274454
|
(1-(((R)-3-methyl-4-(4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)-piperazin-1-yl)methyl)-cyclopropanecarboxamide)
Show/Hide
|
C19H26F3N3O4S
|
2
|
| 1 |
IC50 = 7.3 nM
|
|
|
| 2 |
IC50 = 14 nM
|
|
|
|
CP0540132
|
2-[(2R)-4-(2,5-difluoro-4-methylsulfonylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C27H33F2N5O4S
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0574754
|
2-[(2R)-4-(2-chloro-4-methylsulfonylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C27H34ClN5O4S
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0386770
|
6-[4-(4-carbamoyl-2-chlorophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H32ClN5O3
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0045207
|
(3r,9r)-9-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo[3.3.1]nonane-3-carboxamide
Show/Hide
|
C20H27ClN2O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0398772
|
N-[4-(2-cyano-2,2-dimethylethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H31F3N2O2
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 129 nM
|
|
|
|
CP0093365
|
1-[(2-cyanopyridin-3-yl)methylsulfanyl]-7-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H9FN4OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0093367
|
1-[(2-chlorophenyl)methylsulfanyl]-5-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H10ClFN2OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0284367
|
1-[(2-chlorophenyl)methylsulfanyl]-6-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H10ClFN2OS
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0416528
|
2-nitro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H19F3N2O5S
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 103 nM
|
|
|
|
CP0205402
|
(1R,7S)-4-(3-iodophenyl)-1,3,10,10-tetramethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C18H21IN2O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0566242
|
N-(5-hydroxy-2-adamantyl)-2-[(2R)-2-methyl-4-(2-methyl-4-methylsulfonylphenyl)piperazin-1-yl]pyrimidine-4-carboxamide
Show/Hide
|
C28H37N5O4S
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0164285
|
(1R,2R)-1-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]-7,7-dimethylbicyclo[2.2.1]heptan-2-ol
Show/Hide
|
C22H24ClN3O2
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0487004
|
6-[(2R)-4-(4-carbamoylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C28H35N5O3
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0559050
|
6-[(2R)-4-(4-carbamoylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C28H35N5O3
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0164286
|
8-(3-chloro-2-methylphenoxy)-3-(4-fluoro-1-bicyclo[2.2.2]octanyl)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C21H21ClFN3O
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0577419
|
N-(5-hydroxy-2-adamantyl)-2-[(2R)-2-methyl-4-(4-methylsulfonylphenyl)piperazin-1-yl]pyrimidine-4-carboxamide
Show/Hide
|
C27H35N5O4S
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0052039
|
18beta-glycyrrhetic acid
Show/Hide
|
C30H46O4
|
6
|
| 1 |
IC50 = 8.6 nM
|
|
|
| 2 |
IC50 = 8.8 nM
|
|
|
| 3 |
IC50 = 11.3 nM
|
|
|
| 4 |
IC50 = 13 nM
|
|
|
| 5 |
IC50 = 29.1 nM
|
|
|
| 6 |
IC50 = 778 nM
|
|
|
|
CP0386887
|
CHEMBL3394408
Show/Hide
|
C24H33N3O4
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0578511
|
2-[(2R)-4-[2-fluoro-4-(2-hydroxypropan-2-yl)phenyl]-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C29H38FN5O3
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0199789
|
1-(cyclobutylmethylsulfanyl)-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C15H18N2OS
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0704826
|
rac-2,5-dichloro-N-isopropyl-N-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)benzenesulfonamide
Show/Hide
|
C18H18Cl2F3NO3S
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 54 nM
|
|
|
|
CP0708228
|
rac-2-chloro-N-isopropyl-N-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)benzenesulfonamide
Show/Hide
|
C18H19ClF3NO3S
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 49 nM
|
|
|
|
CP0224347
|
(1R,7S)-3-benzyl-4-(2,4-difluorophenyl)-1,10,10-trimethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C24H24F2N2O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0572587
|
(1R,7S)-3-ethyl-1,10,10-trimethyl-4-phenyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0481878
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-2-methyl-4-[4-(methylcarbamoyl)phenyl]piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C29H37N5O3
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0557062
|
N-(5-hydroxy-2-adamantyl)-2-[(2R)-4-[4-(2-hydroxypropan-2-yl)phenyl]-2-methylpiperazin-1-yl]pyrimidine-4-carboxamide
Show/Hide
|
C29H39N5O3
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0559051
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-2-methyl-4-[4-(methylcarbamoyl)phenyl]piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C29H37N5O3
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0414127
|
CHEMBL3394410
Show/Hide
|
C26H33N5O2
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0379264
|
6-[4-(4-chlorophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C26H31ClN4O2
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0552096
|
2-[(2R)-4-(4-cyanophenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C27H32N6O2
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0379266
|
6-[(2S)-4-(4-cyanophenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C28H33N5O2
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
|
CP0559052
|
N-(5-hydroxy-2-adamantyl)-6-[(2R)-2-methyl-4-(4-sulfamoylphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C27H35N5O4S
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
|
CP0513534
|
2-fluoro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H19F4NO3S
|
2
|
| 1 |
IC50 = 9.9 nM
|
|
|
| 2 |
IC50 = 48 nM
|
|
|
|
CP0528350
|
N-[4-(2-cyanoethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C22H27F3N2O2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
|
CP0062086
|
(2R)-N-(adamantan-2-yl)-1-(oxan-4-ylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C21H34N2O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0238025
|
1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-2H-isoquinoline-4,7-dicarbonitrile
Show/Hide
|
C18H10ClN3OS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0282874
|
(1R,7S)-3-benzyl-1,10,10-trimethyl-4-phenyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C24H26N2O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0135762
|
(S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one
Show/Hide
|
C14H22N2OS
|
1
|
| 1 |
IC50 = 10.1 nM
|
|
|
|
CP0220531
|
N-[4-(cyanomethyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C27H29F3N2O2
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0311741
|
(S)-3'-chloro-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile
Show/Hide
|
C22H15ClF3NO3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0389032
|
3-cyclohexyl-8-[(2,6-dichlorophenyl)sulfanylmethyl]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C19H19Cl2N3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0415507
|
3-cycloheptyl-8-[(2,6-dichlorophenoxy)methyl]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C20H21Cl2N3O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0082646
|
arylsulfonylpiperazine, 18
Show/Hide
|
C20H18F3N3O2S
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 547 nM
|
|
|
|
CP0338183
|
1-[(5-cyano-2-fluorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C18H14FN3OS
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0379265
|
6-[1-(4-cyanophenyl)piperidin-4-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C28H32N4O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0530899
|
N-(5-hydroxy-2-adamantyl)-6-[4-(4-nitrophenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C26H31N5O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0534661
|
3-[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]propan-1-ol
Show/Hide
|
C18H18ClN3O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0147281
|
2-methyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C19H22F3NO3S
|
2
|
| 1 |
IC50 = 11.2 nM
|
|
|
| 2 |
IC50 = 91 nM
|
|
|
|
CP0207477
|
(S)-N-[trans-4-(4-Cyanophenyl)cyclohexyl]-4-[1,1,1-trifluoro-2-hydroxypropan-2-yl]-N-cyclopropylbenzamide
Show/Hide
|
C26H27F3N2O2
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 161 nM
|
|
|
|
CP0102240
|
N-cyclopropyl-N-[4-(2-hydroxyethyl)-4-phenylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C27H32F3NO3
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0280306
|
N-[4-(3-amino-3-oxopropyl)-4-(4-fluorophenyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C28H32F4N2O3
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 55 nM
|
|
|
|
CP0342277
|
4-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]bicyclo[2.2.2]octan-1-ol
Show/Hide
|
C21H22ClN3O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0528765
|
3-chloro-N-[(3-cycloheptyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)methyl]-2-methylbenzenesulfonamide
Show/Hide
|
C21H25ClN4O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0338182
|
1-[2-(2-chlorophenyl)ethylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C18H17ClN2OS
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0418710
|
6-[4-(5-cyanopyridin-2-yl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C26H30N6O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0481877
|
6-[4-(4-carbamoyl-3-fluorophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H32FN5O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0558324
|
2-[(2R)-4-(2,6-difluoro-4-methylsulfonylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
|
C27H33F2N5O4S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0421588
|
(R,S)-2-((+/-)-exo-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one
Show/Hide
|
C14H22N2OS
|
1
|
| 1 |
IC50 = 12.6 nM
|
|
|
|
CP0118608
|
arylsulfonylpiperazine, 19
Show/Hide
|
C20H18F3N3O2S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 329 nM
|
|
|
|
CP0284369
|
8-[(2-chlorophenyl)methylsulfanyl]-6-oxo-1,3,4,7-tetrahydropyrano[3,4-c]pyridine-5-carbonitrile
Show/Hide
|
C16H13ClN2O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0555894
|
(1R,7S)-4-(2-fluorophenyl)-1,10,10-trimethyl-3-propan-2-yl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C20H25FN2O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0572588
|
(1R,7S)-1,3,10,10-tetramethyl-4-[2-(trifluoromethyl)phenyl]-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C19H21F3N2O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0105606
|
3-[1-(4-chlorophenyl)cyclopropyl]-8-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C18H16ClN3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0527809
|
CHEMBL3394398
Show/Hide
|
C21H28F3N3O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0418711
|
6-[4-(2-chloro-4-cyanophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H30ClN5O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0455255
|
4-[(3-Chlorophenylsulfonamido)methyl]-N-(1-adamantyl)benzamide
Show/Hide
|
C24H27ClN2O3S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0315769
|
2,3-dichloro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H18Cl2F3NO3S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 108 nM
|
|
|
|
CP0224815
|
(1R,7S)-4-(2-chlorophenyl)-1,3,10,10-tetramethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C18H21ClN2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0318090
|
(1R,7S)-4-(2,4-difluorophenyl)-1,10,10-trimethyl-3-(2-phenylethyl)-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C25H26F2N2O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0386771
|
N-(5-hydroxy-2-adamantyl)-6-[(2S)-4-(4-methoxyphenyl)-2-methylpiperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C28H36N4O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0466784
|
((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamido)-1-(4-fluorophenyl)cyclohexyl)methyl carbamate
Show/Hide
|
C27H30F4N2O4
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 34 nM
|
|
|
|
CP0145677
|
1-benzylsulfanyl-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H16N2OS
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0121511
|
2-chloro-5-nitro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H18ClF3N2O5S
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 113 nM
|
|
|
|
CP0318091
|
(1R,7S)-1,3,10,10-tetramethyl-4-[[3-(2-methylphenyl)phenyl]methyl]-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C26H30N2O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0418708
|
N-(5-hydroxy-2-adamantyl)-6-[4-(4-methoxyphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C27H34N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0926202
|
(S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthiazol-4(5H)-one
Show/Hide
|
C13H20N2OS
|
1
|
| 1 |
IC50 = 15.3 nM
|
|
|
|
CP0415338
|
[(3S,5R,8R,9R,10R,12R,13S,14R,17R)-3-hydroxy-17-methoxy-4,4,8,10,14-pentamethyl-15-oxo-1,2,3,5,6,7,9,11,12,13,16,17-dodecahydrocyclopenta[a]phenanthren-12-yl] acetate
Show/Hide
|
C25H40O5
|
1
|
| 1 |
IC50 = 15.3 nM
|
|
|
|
CP0922420
|
trans-N-(4-(cyanomethyl)cyclohexyl)-N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide
Show/Hide
|
C21H25F3N2O2
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
|
CP0094336
|
(S)-N-(trans-4-Phenyl)cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylbenzamide
Show/Hide
|
C25H28F3NO2
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 155 nM
|
|
|
|
CP0109467
|
N-[4-(2-amino-2-oxoethyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C27H31F3N2O3
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 92 nM
|
|
|
|
CP0111024
|
((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamido)-1-(thiazol-4-yl)cyclohexyl)methyl carbamate
Show/Hide
|
C24H28F3N3O4S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 63 nM
|
|
|
|
CP0210676
|
1-[(3-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H15ClN2OS
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0062324
|
(4-amino-3,5-dichlorophenyl)(1,3,3-trimethyl-6-aza-bicyclo[3.2.1]octan-6-yl)methanone
Show/Hide
|
C17H22Cl2N2O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0914946
|
trans-N-(4-(3-amino-3-oxopropyl)cyclohexyl)-N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide
Show/Hide
|
C22H29F3N2O3
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 = 77 nM
|
|
|
|
CP0527364
|
2,6-dichloro-N-[(3-cycloheptyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)methyl]benzenesulfonamide
Show/Hide
|
C20H22Cl2N4O2S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0204240
|
[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]methanol
Show/Hide
|
C16H14ClN3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0194127
|
2-(5-bromo-pyridin-2-yloxy)-N-((1R,2S,5R,7S)-5-carbamoylmethyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C21H28BrN3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0291573
|
(S)-N-(cis-4-Phenyl)cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylbenzamide
Show/Hide
|
C25H28F3NO2
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 123 nM
|
|
|
|
CP0400068
|
CHEMBL3394406
Show/Hide
|
C23H31N3O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0400224
|
6-[1-(5-cyanopyridin-2-yl)piperidin-4-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H31N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0577418
|
N-(5-hydroxy-2-adamantyl)-2-[(2R)-2-methyl-4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]pyrimidine-4-carboxamide
Show/Hide
|
C27H32F3N5O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0036385
|
4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclobutanecarbonyl}-amino)-adamantane-1-carboxylic acid amide
Show/Hide
|
C26H34F3N5O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0090112
|
((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamido)-1-(pyridin-2-yl)cyclohexyl)methyl carbamate
Show/Hide
|
C26H30F3N3O4
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 74 nM
|
|
|
|
CP0073737
|
2-chloro-5-methyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C19H21ClF3NO3S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 103 nM
|
|
|
|
CP0121512
|
5-bromo-2-chloro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H18BrClF3NO3S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 106 nM
|
|
|
|
CP0204553
|
2-chloro-N-cyclopropyl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
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C18H17ClF3NO3S
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2
|
| 1 |
IC50 = 19 nM
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| 2 |
IC50 = 411 nM
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CP0418709
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6-[4-(4-fluorophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
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C26H31FN4O2
|
1
|
| 1 |
IC50 = 19 nM
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CP0128629
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(2R)-N-(adamantan-2-yl)-1-(2-hydroxyethyl)pyrrolidine-2-carboxamide
Show/Hide
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C17H28N2O2
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1
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| 1 |
IC50 = 20 nM
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CP0282875
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(1R,7S)-4-(2-fluorophenyl)-1,10,10-trimethyl-3-propyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
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C20H25FN2O
|
1
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| 1 |
IC50 = 20 nM
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CP0180623
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(S)-3'-(2-fluoroethyl)-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile
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C24H19F4NO3S
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1
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| 1 |
IC50 = 20.7 nM
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CP0645488
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4-[2-(4-methoxy-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid amide
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C22H30N2O4
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1
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| 1 |
IC50 = 21 nM
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CP0167343
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N-(5-hydroxy-2-adamantyl)-2-(6,7,9,10-tetrahydro-[1,3]dioxolo[4,5-i][3]benzazepin-8-yl)propanamide
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C24H32N2O4
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1
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| 1 |
IC50 = 21 nM
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CP0502285
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
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C21H26F3N3O3S
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1
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| 1 |
IC50 = 21 nM
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CP0398261
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CHEMBL3394393
Show/Hide
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C20H29N3O2
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1
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| 1 |
IC50 = 21 nM
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CP0379262
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6-[4-(4-carbamoylphenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
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C27H33N5O3
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1
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| 1 |
IC50 = 21 nM
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CP0559053
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2-[(2R)-4-(4-chlorophenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
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C26H32ClN5O2
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1
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| 1 |
IC50 = 21 nM
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CP0137352
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(3s,9s)-9-(2-(5-cyanopyridin-2-yloxy)-2-methylpropanamido)bicyclo[3.3.1]nonane-3-carboxamide
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C20H26N4O3
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1
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| 1 |
IC50 = 22 nM
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CP0766570
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4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid amide
Show/Hide
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C21H27ClN2O3
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1
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| 1 |
IC50 = 22 nM
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CP0206409
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4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclopropanecarbonyl}-amino)-adamantane-1-carboxylic acid amide
Show/Hide
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C25H32F3N5O2
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1
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| 1 |
IC50 = 22 nM
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CP0149591
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(2R)-N-(adamantan-2-yl)-1-methylpyrrolidine-2-carboxamide
Show/Hide
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C16H26N2O
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1
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| 1 |
IC50 = 22 nM
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CP0314759
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3-chloro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
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C18H19ClF3NO3S
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2
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| 1 |
IC50 = 22 nM
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| 2 |
IC50 = 262 nM
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CP0205403
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(1R,7S)-4-(2-fluorophenyl)-1,10,10-trimethyl-3-prop-2-enyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
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C20H23FN2O
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1
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| 1 |
IC50 = 22 nM
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CP0384748
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6-[4-(4-cyano-3-fluorophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
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C27H30FN5O2
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1
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| 1 |
IC50 = 22 nM
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CP0574753
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2-[(2R)-4-(4-fluorophenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
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C26H32FN5O2
|
1
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| 1 |
IC50 = 22 nM
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CP0253165
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8-(3-chloro-2-methylphenoxy)-3-cycloheptyl-[1,2,4]triazolo[4,3-a]pyridine
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C20H22ClN3O
|
1
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| 1 |
IC50 = 23 nM
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CP0311882
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(1R,7S)-4-(3-methoxyphenyl)-1,3,10,10-tetramethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
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C19H24N2O2
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1
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| 1 |
IC50 = 23 nM
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CP0379263
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N-(5-hydroxy-2-adamantyl)-6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
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C27H31F3N4O2
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1
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| 1 |
IC50 = 23 nM
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CP0655739
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4-(2-methyl-2-phenoxy-propionylamino)-adamantane-1-carboxylic acid amide
Show/Hide
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C21H28N2O3
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1
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| 1 |
IC50 = 24 nM
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CP0036381
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4-{2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-butyrylamino}-adamantane-1-carboxylic acid amide
Show/Hide
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C25H34F3N5O2
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1
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| 1 |
IC50 = 24 nM
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CP0128806
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(S)-N-Cyclohexyl-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-(2,2,2-trifluoroethyl)benzamide
Show/Hide
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C18H21F6NO2
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2
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| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 163 nM
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CP0259524
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1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)piperazin-1-yl)methyl)cyclopropanecarboxamide
Show/Hide
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C19H26F3N3O4S
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1
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| 1 |
IC50 = 25.4 nM
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CP0509965
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N-cyclopropyl-N-(4-hydroxy-4-propan-2-ylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
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C22H30F3NO3
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2
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| 1 |
IC50 = 26 nM
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| 2 |
IC50 = 69 nM
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CP0431380
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-3-yl)cyclopropyl)methyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C23H28F3N3O3S
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1
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| 1 |
IC50 = 27 nM
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CP0529012
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-3-yl)cyclobutyl)methyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C24H30F3N3O3S
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1
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| 1 |
IC50 = 27 nM
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CP0474819
|
CHEMBL473347
Show/Hide
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C23H30F3NO3
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2
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| 1 |
IC50 = 27 nM
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| 2 |
IC50 = 154 nM
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CP0411291
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N-(4-hydroxycyclohexyl)-6-piperidin-1-ylpyridine-2-carboxamide
Show/Hide
|
C17H25N3O2
|
1
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| 1 |
IC50 = 27 nM
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CP0162641
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4-[4-(4-imidazol-1-yl-phenoxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-adamantane-1-carboxylic acid amide
Show/Hide
|
C27H34N4O3
|
1
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| 1 |
IC50 = 28 nM
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CP0036376
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N-(5-hydroxy-2-adamantyl)-2-methyl-2-piperidin-1-ylpropanamide
Show/Hide
|
C19H32N2O2
|
1
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| 1 |
IC50 = 28 nM
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CP0351939
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2-[4-(2-cyclopropylphenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
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C18H17F3O3S
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1
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| 1 |
IC50 = 28 nM
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CP0036916
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2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4-yl)-N,N-diethylacetamide
Show/Hide
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C16H20ClN3O3S2
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1
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| 1 |
IC50 = 28.4 nM
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CP0524002
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(S)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one
Show/Hide
|
C14H22N2OS
|
1
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| 1 |
IC50 = 28.6 nM
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CP0203522
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1-naphthalen-2-ylsulfonyl-4-phenyl-3,6-dihydro-2H-pyridine
Show/Hide
|
C21H19NO2S
|
1
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| 1 |
IC50 = 28.8 nM
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CP0045322
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N-(5-hydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C23H31F3N4O2
|
1
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| 1 |
IC50 = 29 nM
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CP0212300
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4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclopentanecarbonyl}-amino)-adamantane-1-carboxylic acid amide
Show/Hide
|
C27H36F3N5O2
|
1
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| 1 |
IC50 = 29 nM
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CP0412297
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-3-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C21H26F3N3O3S
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1
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| 1 |
IC50 = 29 nM
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CP0204555
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2-chloro-N-(1,3-difluoropropan-2-yl)-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H17ClF5NO3S
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2
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 162 nM
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CP0247227
|
2-cyano-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C19H19F3N2O3S
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2
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| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 261 nM
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CP0400403
|
6-[4-(5-cyanopyridin-2-yl)piperidin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C27H31N5O2
|
1
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| 1 |
IC50 = 29 nM
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CP0474991
|
1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-3-yl)cyclopentyl)methyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C25H32F3N3O3S
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1
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| 1 |
IC50 = 30 nM
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CP0466785
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((1R)-4-(N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamido)-1-(5-fluoropyridin-2-yl)cyclohexyl)methyl carbamate
Show/Hide
|
C26H29F4N3O4
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2
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| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 93 nM
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CP0217235
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2-(4-chloro-phenoxy)-N-((1R,2S,5S,7S)-5-isoxazol-5-yl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C23H27ClN2O3
|
1
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| 1 |
IC50 = 31 nM
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CP0236503
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1-(2-chlorophenyl)sulfanyl-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C16H13ClN2OS
|
1
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| 1 |
IC50 = 31 nM
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CP0916677
|
1-Adamantan-1-yl-2-(5-methyl-[1,3,4]thiadiazole-2-sulfonyl)-ethanone
Show/Hide
|
C15H20N2O3S2
|
1
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| 1 |
IC50 = 31 nM
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CP0169477
|
(1R,7S)-1,3,10,10-tetramethyl-4-phenyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C18H22N2O
|
1
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| 1 |
IC50 = 31 nM
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CP0324401
|
(1R,7S)-4-benzyl-1,3,10,10-tetramethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C19H24N2O
|
1
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| 1 |
IC50 = 31 nM
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CP0253702
|
1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-naphthalen-2-ylsulfonylpiperazine
Show/Hide
|
C20H17ClF3N3O2S
|
1
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| 1 |
IC50 = 32.7 nM
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CP0344777
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-4-yl)cyclopropyl)methyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C23H28F3N3O3S
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1
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| 1 |
IC50 = 33 nM
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CP0517454
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2-(4-((R)-4-(2,2-difluoro-2-(pyridin-4-yl)ethyl)-2-methylpiperazin-1-ylsulfonyl)phenyl)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C21H24F5N3O3S
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1
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| 1 |
IC50 = 33 nM
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CP0436758
|
3-cycloheptyl-8-[(2,6-dichlorophenyl)methoxymethyl]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C21H23Cl2N3O
|
1
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| 1 |
IC50 = 34 nM
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CP0448210
|
[(3S,5R,8R,9R,10R,12R,13R,14R)-3-hydroxy-4,4,8,10,14-pentamethyl-15-oxo-1,2,3,5,6,7,9,11,12,13-decahydrocyclopenta[a]phenanthren-12-yl] acetate
Show/Hide
|
C24H36O4
|
1
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| 1 |
IC50 = 34.1 nM
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CP0200219
|
N-(5-hydroxy-2-adamantyl)-2-[(3S)-3-(trifluoromethyl)pyrrolidin-1-yl]acetamide
Show/Hide
|
C17H25F3N2O2
|
1
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| 1 |
IC50 = 35 nM
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CP0517452
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-4-yl)cyclopentyl)methyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C25H32F3N3O3S
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1
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| 1 |
IC50 = 35 nM
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CP0429308
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N-(5-hydroxy-2-adamantyl)-6-[4-(4-methylphenyl)piperazin-1-yl]pyridine-2-carboxamide
Show/Hide
|
C27H34N4O2
|
1
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| 1 |
IC50 = 35 nM
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CP0172464
|
4-[2-(3,3-difluoro-piperidin-1-yl)-butyrylamino]-adamantane-1-carboxylic acid amide
Show/Hide
|
C20H31F2N3O2
|
1
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| 1 |
IC50 = 36 nM
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CP0386472
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N-(4-cyano-4-cyclopropylcyclohexyl)-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C23H27F3N2O2
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2
|
| 1 |
IC50 = 36 nM
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| 2 |
IC50 = 64 nM
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CP0256274
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(S)-N-(trans-4-Fluorocyclohexyl)-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)-N-cyclopropylbenzamide
Show/Hide
|
C19H23F4NO2
|
2
|
| 1 |
IC50 = 36 nM
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| 2 |
IC50 = 140 nM
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CP0528764
|
3-cycloheptyl-8-(2,6-dichlorophenoxy)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C19H19Cl2N3O
|
1
|
| 1 |
IC50 = 36 nM
|
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CP0052162
|
4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclobutanecarbonyl}-amino)-adamantane-1-carboxylic acid
Show/Hide
|
C26H33F3N4O3
|
1
|
| 1 |
IC50 = 37 nM
|
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CP0141752
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N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-methyl-2-(5-pyrazol-1-ylpyridin-2-yl)oxypropanamide
Show/Hide
|
C24H31N5O3
|
1
|
| 1 |
IC50 = 38 nM
|
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CP0161868
|
4-{2-cyclopropyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-acetylamino}-adamantane-1-carboxylic acid amide
Show/Hide
|
C26H34F3N5O2
|
1
|
| 1 |
IC50 = 38 nM
|
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CP0245172
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N-cyclohexyl-N-(cyclopropylmethyl)-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide
Show/Hide
|
C20H26F3NO2
|
2
|
| 1 |
IC50 = 38 nM
|
|
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| 2 |
IC50 = 849 nM
|
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CP0102627
|
4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-propionylamino}-adamantane-1-carboxylic acid
Show/Hide
|
C25H33F3N4O3
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0514716
|
CHEMBL2021498
Show/Hide
|
C25H26F3N3O2
|
2
|
| 1 |
IC50 = 39 nM
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|
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| 2 |
IC50 > 300 nM
|
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CP0289292
|
3-chloro-4-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylbenzonitrile
Show/Hide
|
C16H11ClF3NO3S
|
1
|
| 1 |
IC50 = 39 nM
|
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CP0274946
|
(4-amino-3,5-dichloro-phenyl)-(2-aza-tricyclo[3.3.1.1*3,7*]dec-2-yl)-methanone
Show/Hide
|
C16H18Cl2N2O
|
1
|
| 1 |
IC50 = 41 nM
|
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CP0502585
|
N-(4-cyano-4-pyridin-2-ylcyclohexyl)-N-cyclopropyl-4-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C25H26F3N3O2
|
2
|
| 1 |
IC50 = 41 nM
|
|
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| 2 |
IC50 > 300 nM
|
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CP0140363
|
N-cyclopropyl-N-[4-(hydroxymethyl)-4-phenylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C26H30F3NO3
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
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CP0525145
|
6-[4-(4-aminophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
|
C26H33N5O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
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CP0235642
|
N-benzyl-4-(3-chloro-2-cyanophenoxy)-N-methylbenzenesulfonamide
Show/Hide
|
C21H17ClN2O3S
|
1
|
| 1 |
IC50 = 41.3 nM
|
|
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CP0204554
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N-tert-butyl-2-chloro-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
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C19H21ClF3NO3S
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2
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| 1 |
IC50 = 42 nM
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| 2 |
IC50 = 614 nM
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CP0848109
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(3beta,18beta,20beta)-3-Methoxyamino-11-oxo-olean-12-en-29-oic acid hydrochloride
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C31H50ClNO4
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1
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| 1 |
IC50 = 42.7 nM
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CP0274991
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4-[3,3-dimethyl-2-oxo-4-(4-[1,2,4]triazol-1-yl-phenoxymethyl)-pyrrolidin-1-yl]-adamantane-1-carboxylic acid amide
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C26H33N5O3
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1
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| 1 |
IC50 = 43 nM
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CP0517453
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1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-4-yl)cyclobutyl)methyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
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C24H30F3N3O3S
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1
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| 1 |
IC50 = 43 nM
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CP0350975
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2-[4-(2,4-dichlorophenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
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C15H11Cl2F3O3S
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1
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| 1 |
IC50 = 43 nM
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CP0326315
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4-[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]-2-methylbutan-2-ol
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C20H22ClN3O
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1
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| 1 |
IC50 = 43 nM
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CP0111847
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4-[4-(5-cyano-pyridin-2-yloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-adamantane-1-carboxylic acid amide
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C24H30N4O3
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1
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| 1 |
IC50 = 45 nM
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CP0102623
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4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-propionylamino}-adamantane-1-carboxylic acid amide
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C25H34F3N5O2
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1
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| 1 |
IC50 = 45 nM
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CP0206284
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4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclopropanecarbonyl}-amino)-adamantane-1-carboxylic acid
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C25H31F3N4O3
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1
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| 1 |
IC50 = 45 nM
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CP0203339
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3-[(2-chloro-6-fluorophenyl)methylsulfanyl]-5-(furan-2-yl)-4-(4-phenylmethoxyphenyl)-1,2,4-triazole
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C26H19ClFN3O2S
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1
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| 1 |
IC50 = 45 nM
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CP0045323
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N-(5-hydroxy-2-adamantyl)-2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
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C24H33F3N4O2
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1
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| 1 |
IC50 = 46 nM
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CP0500697
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(E)-N-(5-methoxy-adamantan-2-yl)-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-propionamide
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C24H33F3N4O2
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1
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| 1 |
IC50 = 46 nM
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CP0215568
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2-chloro-N-cyclobutyl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
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C19H19ClF3NO3S
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2
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| 1 |
IC50 = 46 nM
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| 2 |
IC50 = 441 nM
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CP0531874
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(R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(3-(pyridin-4-yl)propyl)piperazine
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C23H33N3O2S
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1
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| 1 |
IC50 = 47 nM
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CP0496192
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N-butyl-4-[[(3-chlorophenyl)sulfonylamino]methyl]-N-cycloheptylbenzamide
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C25H33ClN2O3S
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1
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| 1 |
IC50 = 47 nM
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CP0385533
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2-chloro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]-5-(trifluoromethyl)benzenesulfonamide
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C19H18ClF6NO3S
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2
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| 1 |
IC50 = 47 nM
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| 2 |
IC50 = 268 nM
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CP0386730
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CHEMBL2021499
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C26H26F4N2O2
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2
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| 1 |
IC50 = 48 nM
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| 2 |
IC50 > 300 nM
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CP0474821
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N-cyclopropyl-N-(4-hydroxy-4-phenylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
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C25H28F3NO3
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2
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| 1 |
IC50 = 48 nM
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| 2 |
IC50 > 300 nM
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CP0455309
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4-[(3-Chlorophenylsulfonamido)methyl]-N-cycloheptylbenzamide
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C21H25ClN2O3S
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1
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| 1 |
IC50 = 49 nM
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CP0284374
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1-[(2-methylsulfonylphenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
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C18H18N2O3S2
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1
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| 1 |
IC50 = 49 nM
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CP0289288
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2-[4-(2-chlorophenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
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C15H12ClF3O3S
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1
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| 1 |
IC50 = 50 nM
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CP0102255
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N-cyclopropyl-N-(4-cyclopropyl-4-hydroxycyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
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C22H28F3NO3
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2
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| 1 |
IC50 = 52 nM
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| 2 |
IC50 = 121 nM
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CP0858422
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cis-N-(4-(cyanomethyl)cyclohexyl)-N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide
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C21H25F3N2O2
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2
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| 1 |
IC50 = 52 nM
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| 2 |
IC50 = 202 nM
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CP0645485
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2-(4-chloro-phenoxy)-N-(5-hydroxymethyl-adamantan-2-yl)-2-methyl-propionamide
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C21H28ClNO3
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1
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| 1 |
IC50 = 53 nM
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CP0136126
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2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-2-(2-trifluoromethoxy-phenoxy)-propionamide
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C21H27F3N2O5S
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1
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| 1 |
IC50 = 54 nM
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CP0766281
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2-(2-chloro-4-fluoro-phenoxy)-2-methyl-N-[5-(1H-tetrazol-5-yl)-adamantan-2-yl]-propionamide
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C21H25ClFN5O2
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1
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| 1 |
IC50 = 54 nM
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CP0542921
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(R)-(1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)cyclopropyl)methanol
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C22H29N3O3S
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1
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| 1 |
IC50 = 55 nM
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CP0422722
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N-{1-[(1-cyanocyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
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C23H28F3N3O2
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2
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| 1 |
IC50 = 56 nM
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| 2 |
IC50 = 108 nM
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CP0311736
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1,1,1-trifluoro-2-[4-(2-methylphenyl)sulfonylphenyl]propan-2-ol
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C16H15F3O3S
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1
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| 1 |
IC50 = 56 nM
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CP0520657
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(R)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one
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C14H22N2OS
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1
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| 1 |
IC50 = 56.8 nM
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CP0082642
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(2R)-1-(4-tert-butylphenyl)sulfonyl-2-methyl-4-(4-nitrophenyl)piperazine
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C21H27N3O4S
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1
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| 1 |
IC50 = 57 nM
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CP0400405
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6-[4-(4-cyanophenyl)piperidin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
Show/Hide
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C28H32N4O2
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1
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| 1 |
IC50 = 57 nM
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CP0398495
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N-cyclohexyl-6-piperidin-1-ylpyridine-2-carboxamide
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C17H25N3O
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1
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| 1 |
IC50 = 58 nM
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CP0253704
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1-(2,3-Dihydro-indol-1-yl)-2-(5,6-diphenyl-[1,2,4]triazin-3-ylsulfanyl)-ethanone
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C25H20N4OS
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1
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| 1 |
IC50 = 58.1 nM
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CP0655742
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4-[2-(2-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid
Show/Hide
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C21H26ClNO4
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1
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| 1 |
IC50 = 59 nM
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CP0766279
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4-[({4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carbonyl}-amino)-methyl]-benzoic acid
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C29H33ClN2O5
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1
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| 1 |
IC50 = 59 nM
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CP0289291
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2-[4-(4-bromo-2-chlorophenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
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C15H11BrClF3O3S
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1
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| 1 |
IC50 = 59 nM
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CP0322334
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(1S,7R)-1,3,10,10-tetramethyl-4-phenyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
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C18H22N2O
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1
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| 1 |
IC50 = 60 nM
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CP0511450
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(R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazine
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C22H31N3O2S
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1
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| 1 |
IC50 = 61 nM
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CP0965223
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1-Adamantan-1-yl-2-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanyl)-ethanone
Show/Hide
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C15H20N2OS2
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1
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| 1 |
IC50 = 61 nM
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CP0845174
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(3alpha,18beta,20beta)-3-Methoxyamino-11-oxo-olean-12-en-29-oic acid hydrochloride
Show/Hide
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C31H50ClNO4
|
1
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| 1 |
IC50 = 61.9 nM
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CP0514730
|
CHEMBL517760
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C26H27F3N2O2
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2
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| 1 |
IC50 = 62 nM
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| 2 |
IC50 = 219 nM
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CP0454250
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(R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one
Show/Hide
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C14H22N2OS
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1
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| 1 |
IC50 = 62 nM
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CP0215567
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5-amino-2-chloro-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C18H20ClF3N2O3S
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2
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| 1 |
IC50 = 63 nM
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| 2 |
IC50 = 271 nM
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CP0073872
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3-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]adamantan-1-ol
Show/Hide
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C23H24ClN3O2
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1
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| 1 |
IC50 = 64 nM
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CP0235641
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(E)-2-(2,4-dichlorophenyl)sulfonyl-3-(2,3-dihydro-1-benzofuran-5-yl)prop-2-enenitrile
Show/Hide
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C17H11Cl2NO3S
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1
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| 1 |
IC50 = 66.7 nM
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CP0528379
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(R)-2-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
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C21H29N3O3S
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1
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| 1 |
IC50 = 69 nM
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CP0474297
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1-(4-((R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)ethanol
Show/Hide
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C20H27N3O3S
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1
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| 1 |
IC50 = 70 nM
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CP0136849
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2-[3-(2-fluoro-phenoxy)-azetidin-1-yl]-N-(5-hydroxy-adamantan-2-yl)-propionamide
Show/Hide
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C22H29FN2O3
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1
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| 1 |
IC50 = 71 nM
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CP0422529
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(2R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)-1-(4-(1,1,1,2-tetrafluoropropan-2-yl)phenylsulfonyl)piperazine
Show/Hide
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C21H25F4N3O2S
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1
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| 1 |
IC50 = 71 nM
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CP0204551
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N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]-2-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C19H19F6NO3S
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2
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| 1 |
IC50 = 71 nM
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| 2 |
IC50 = 769 nM
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CP0356968
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1-[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]ethane-1,2-diol
Show/Hide
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C17H16ClN3O2
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1
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| 1 |
IC50 = 71 nM
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CP0257107
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3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dimethylpiperidin-4-yl)benzo[d]oxazol-2(3H)-one
Show/Hide
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C21H21Cl2N3O3
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1
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| 1 |
IC50 = 72 nM
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CP0345657
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8-(3-chloro-2-methylphenoxy)-3-(4-methoxy-1-bicyclo[2.2.2]octanyl)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
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C22H24ClN3O2
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1
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| 1 |
IC50 = 72 nM
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CP0286513
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(3s,9s)-9-(2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanamido)bicyclo[3.3.1]nonane-3-carboxamide
Show/Hide
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C24H34F3N5O2
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1
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| 1 |
IC50 = 73 nM
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CP0046007
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(3r,8r)-8-(2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanamido)bicyclo[3.2.1]octane-3-carboxylic acid
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C23H31F3N4O3
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1
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| 1 |
IC50 = 75 nM
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CP0453424
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[(3S,5R,8R,9R,10R,12R,13S,14R,17R)-3,17-dihydroxy-4,4,8,10,14-pentamethyl-15-oxo-1,2,3,5,6,7,9,11,12,13,16,17-dodecahydrocyclopenta[a]phenanthren-12-yl] acetate
Show/Hide
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C24H38O5
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1
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| 1 |
IC50 = 75.5 nM
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CP0051767
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1-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dimethylpiperidin-4-yl)imidazolidin-2-one
Show/Hide
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C17H22Cl2N4O2
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1
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| 1 |
IC50 = 76 nM
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CP0431381
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2-(4-((R)-4-(2,2-difluoro-2-(pyridin-3-yl)ethyl)-2-methylpiperazin-1-ylsulfonyl)phenyl)-1,1,1-trifluoropropan-2-ol
Show/Hide
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C21H24F5N3O3S
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1
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| 1 |
IC50 = 78 nM
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CP0526784
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(R)-4-((4-(4-tert-butylphenylsulfonyl)-3-methylpiperazin-1-yl)methyl)quinoline
Show/Hide
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C25H31N3O2S
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1
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| 1 |
IC50 = 78 nM
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CP0335646
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1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
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C17H15ClN2OS
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1
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| 1 |
IC50 = 78 nM
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CP0083549
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(3s,9s)-9-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo[3.3.1]nonane-3-carboxylic acid
Show/Hide
|
C20H26ClNO4
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1
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| 1 |
IC50 = 80 nM
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CP0320947
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(4-methyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
|
C23H32N2O
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1
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| 1 |
IC50 = 80 nM
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CP0110246
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2-[(3S)-4-[[2-(4-chlorophenoxy)-2-methylpropanoyl]amino]-1-adamantyl]acetic acid
Show/Hide
|
C22H28ClNO4
|
1
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| 1 |
IC50 = 82 nM
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CP0431578
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N-[4-cyano-4-(4-cyanophenyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C27H26F3N3O2
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2
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| 1 |
IC50 = 82 nM
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| 2 |
IC50 > 300 nM
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CP0157266
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2-(2-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C20H27ClN2O4S
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1
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| 1 |
IC50 = 83 nM
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CP0335645
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1-[(4-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H15ClN2OS
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1
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| 1 |
IC50 = 85 nM
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CP0525788
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(R)-1-(4-(1,1-difluoroethyl)phenylsulfonyl)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazine
Show/Hide
|
C20H25F2N3O2S
|
1
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| 1 |
IC50 = 86 nM
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CP0283357
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N-cyclopropyl-N-[4-(methanesulfonamidomethyl)-4-phenylcyclohexyl]-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C27H33F3N2O4S
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2
|
| 1 |
IC50 = 86 nM
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| 2 |
IC50 = 259 nM
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CP0206408
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4-{2-cyclopropyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-acetylamino}-adamantane-1-carboxylic acid
Show/Hide
|
C26H33F3N4O3
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1
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| 1 |
IC50 = 87 nM
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CP0558227
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(1R,7S)-1,3,10,10-tetramethyl-4-(4-methylphenyl)-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C19H24N2O
|
1
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| 1 |
IC50 = 89 nM
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CP0645487
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4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-amide
Show/Hide
|
C27H32ClN3O3
|
1
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| 1 |
IC50 = 91 nM
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CP0704322
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4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid (thiazol-5-ylmethyl)-amide
Show/Hide
|
C25H30ClN3O3S
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1
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| 1 |
IC50 = 92 nM
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CP0463304
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1-(3,4-dimethoxyphenyl)-2-(1-m-tolyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
|
C19H19N3O3S
|
1
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| 1 |
IC50 = 93 nM
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CP0294505
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2-[4-(2-ethylphenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C17H17F3O3S
|
1
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| 1 |
IC50 = 93 nM
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|
CP0169239
|
4-[1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinolin-4-yl]benzonitrile
Show/Hide
|
C23H19ClN2OS
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0501843
|
(2R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(1-(pyridin-4-yl)ethyl)piperazine
Show/Hide
|
C22H31N3O2S
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0514728
|
N-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-N-cyclopropyl-4-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C26H26F4N2O2
|
2
|
| 1 |
IC50 = 96 nM
|
|
|
| 2 |
IC50 > 300 nM
|
|
|
|
CP0474822
|
N-cyclopropyl-N-(4-hydroxy-4-methylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C20H26F3NO3
|
2
|
| 1 |
IC50 = 97 nM
|
|
|
| 2 |
IC50 > 300 nM
|
|
|
|
CP0553973
|
4-[(3R)-4-[6-[(5-hydroxy-2-adamantyl)carbamoyl]pyridin-2-yl]-3-methylpiperazin-1-yl]benzoic acid
Show/Hide
|
C28H34N4O4
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0035623
|
2-(2-chloro-4-fluoro-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C21H27ClFNO4S
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0212480
|
N-(1-adamantyl)-4-amino-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C18H22Cl2N2O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0488971
|
[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-acetyloxy-4,4,8,10,14-pentamethyl-17-(5-methylhexanoyl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
Show/Hide
|
C33H54O5
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0332685
|
2,5-dichloro-N-[3-(2-pyridin-2-ylethyl)phenyl]benzenesulfonamide
Show/Hide
|
C19H16Cl2N2O2S
|
1
|
| 1 |
IC50 = 102.4 nM
|
|
|
|
CP0273840
|
7-benzyl-1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-2,5,6,8-tetrahydro-2,7-naphthyridine-4-carbonitrile
Show/Hide
|
C23H20ClN3OS
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0076398
|
2-[4-(2-chloro-4-nitrophenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C15H11ClF3NO5S
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0870115
|
cis-N-(4-(3-amino-3-oxopropyl)cyclohexyl)-N-cyclopropyl-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide
Show/Hide
|
C22H29F3N2O3
|
2
|
| 1 |
IC50 = 109 nM
|
|
|
| 2 |
IC50 = 417 nM
|
|
|
|
CP0291062
|
2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(1H-imidazol-2-yl)-adamantan-2-yl]-2-methyl-propionamide
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0526913
|
N-(5-hydroxy-7-methoxy-2-adamantyl)-2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C25H35F3N4O3
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0289293
|
2-[4-(2-chloro-4-pyridin-4-ylphenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C20H15ClF3NO3S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0416524
|
2-chloro-N-(cyclopropylmethyl)-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C19H19ClF3NO3S
|
2
|
| 1 |
IC50 = 112 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0386454
|
3-(1-(3-chlorophenyl)-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0199949
|
N-methyl-N-[(1-methylpyrrol-2-yl)methyl]adamantane-1-carboxamide
Show/Hide
|
C18H26N2O
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
|
CP0417688
|
1-(3,4-dimethoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
|
C18H17N3O3S
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0435861
|
N-[(3-aminophenyl)methyl]-N-methyladamantane-1-carboxamide
Show/Hide
|
C19H26N2O
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0077765
|
2-(4-chloro-phenoxy)-2-methyl-N-[(1S,2S,5R,7S)-5-(1H-tetrazol-5-ylmethyl)-adamantan-2-yl]-propionamide
Show/Hide
|
C22H28ClN5O2
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0136127
|
2-methyl-N-(5-methylsulfonyl-2-adamantyl)-2-[2-(trifluoromethyl)phenoxy]propanamide
Show/Hide
|
C22H28F3NO4S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0254158
|
2-(2-chloro-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C21H28ClNO4S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0704323
|
4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid carbamoylmethyl-amide
Show/Hide
|
C23H30ClN3O4
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0453647
|
N-(5-fluoro-7-hydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C23H30F4N4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0285509
|
2-(4-chloro-phenoxy)-N-[(1R,2S,5S,7S)-5-(N-hydroxycarbamimidoyl)-adamantan-2-yl]-2-methyl-propionamide
Show/Hide
|
C21H28ClN3O3
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0145613
|
2-(2-chloro-4-fluoro-phenoxy)-2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C20H26ClFN2O4S
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0291161
|
(R)-3'-cyclopropyl-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile
Show/Hide
|
C25H20F3NO3S
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0484881
|
N-methyl-N-(thiophen-3-ylmethyl)adamantane-1-carboxamide
Show/Hide
|
C17H23NOS
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
|
CP0247579
|
1-(((R)-3-methyl-4-(4-((R)-1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)piperazin-1-yl)methyl)cyclopropanecarboxamide
Show/Hide
|
C19H26F3N3O4S
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0343525
|
1,1,1-trifluoro-2-[4-(2-fluorophenyl)sulfonylphenyl]propan-2-ol
Show/Hide
|
C15H12F4O3S
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0045301
|
N-(5-hydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
Show/Hide
|
C22H29F3N4O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0144600
|
4-amino-3,5-dichloro-N-cyclohexyl-N-cyclopropylbenzamide
Show/Hide
|
C16H20Cl2N2O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0506437
|
1,1,1-trifluoro-2-(4-((R)-2-methyl-4-(2-(pyridin-2-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)propan-2-ol
Show/Hide
|
C21H26F3N3O3S
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0147283
|
2-chloro-5-cyclopropyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C21H23ClF3NO3S
|
2
|
| 1 |
IC50 = 133 nM
|
|
|
| 2 |
IC50 = 612 nM
|
|
|
|
CP0093371
|
1-[(2-methoxyphenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C18H18N2O2S
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0502284
|
(2R)-1-(4-(1-fluoroethyl)phenylsulfonyl)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazine
Show/Hide
|
C20H26FN3O2S
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0323152
|
2-chloro-N-propan-2-yl-N-[4-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl]benzenesulfonamide
Show/Hide
|
C18H19ClF3NO3S
|
2
|
| 1 |
IC50 = 138 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0235870
|
1-(3-methoxyphenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanone
Show/Hide
|
C12H12N2O2S2
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0212505
|
4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbenzamide
Show/Hide
|
C15H18Cl2N2O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0437486
|
(3beta,18beta,20beta)-[3-(1,2,4-Oxadiazole-5(2H)-one)]-11-oxoolean-12-en-29-oic acid
Show/Hide
|
C32H46N2O6
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0521844
|
3-cyclohexyl-8-[(2,6-dichlorophenoxy)methyl]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C19H19Cl2N3O
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0215569
|
2-chloro-N-cyclopentyl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C20H21ClF3NO3S
|
2
|
| 1 |
IC50 = 144 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0517558
|
2-cyclopropyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C21H24F3NO3S
|
2
|
| 1 |
IC50 = 144 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0351938
|
1,1,1-trifluoro-2-[4-[2-(trifluoromethyl)phenyl]sulfonylphenyl]propan-2-ol
Show/Hide
|
C16H12F6O3S
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0386258
|
(R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(pyridin-4-ylmethyl)piperazine
Show/Hide
|
C21H29N3O2S
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0398774
|
N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C23H30F3N3O3
|
2
|
| 1 |
IC50 = 148 nM
|
|
|
| 2 |
IC50 = 167 nM
|
|
|
|
CP0043473
|
3-(2-bicyclo[2.2.1]heptanylmethyl)-8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0131997
|
N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-(5-cyanopyridin-2-yl)-2-methylpropanamide
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0124804
|
(R)-3'-chloro-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile
Show/Hide
|
C22H15ClF3NO3S
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0392284
|
N-methyl-N-(2-pyridin-2-ylethyl)adamantane-1-carboxamide
Show/Hide
|
C19H26N2O
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0131990
|
N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-methyl-2-(6-morpholin-4-ylpyridin-3-yl)propanamide
Show/Hide
|
C25H36N4O3
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
|
CP0386728
|
CHEMBL517434
Show/Hide
|
C24H27F3N2O3
|
2
|
| 1 |
IC50 = 170 nM
|
|
|
| 2 |
IC50 > 300 nM
|
|
|
|
CP0095261
|
(3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone
Show/Hide
|
C22H29NO
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0203718
|
(2R)-2-[(3R)-3-fluoropyrrolidin-1-yl]-N-(5-hydroxy-2-adamantyl)propanamide
Show/Hide
|
C17H27FN2O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0463305
|
2-(1-cyclohexyl-1H-tetrazol-5-ylthio)-1-(3,4-dimethoxyphenyl)ethanone
Show/Hide
|
C18H23N3O3S
|
1
|
| 1 |
IC50 = 183 nM
|
|
|
|
CP0330754
|
1-[[3-chloro-4-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylphenyl]methyl]cyclopropane-1-carbonitrile
Show/Hide
|
C20H17ClF3NO3S
|
1
|
| 1 |
IC50 = 184 nM
|
|
|
|
CP0035039
|
(1R,7S,8r)-4-(2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanamido)bicyclo[5.1.0]octane-8-carboxamide
Show/Hide
|
C23H32F3N5O2
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0147268
|
2-chloro-N-(2-methylpropyl)-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C19H21ClF3NO3S
|
2
|
| 1 |
IC50 = 185 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0302293
|
2-(2,6-dichloro-4-fluoro-phenoxy)-2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C20H25Cl2FN2O4S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0655741
|
4-[2-(3-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid
Show/Hide
|
C21H26ClNO4
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0422329
|
N-(2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
Show/Hide
|
C22H29F3N4O
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0257108
|
(4-amino-3,5-dichlorophenyl)((2R,6S)-4-(2-methoxyphenyl)-2,6-dimethylpiperazin-1-yl)methanone
Show/Hide
|
C20H23Cl2N3O2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0474820
|
CHEMBL460924
Show/Hide
|
C25H26F3N3O2
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 > 300 nM
|
|
|
|
CP0320948
|
1-adamantyl(piperidin-1-yl)methanone
Show/Hide
|
C16H25NO
|
1
|
| 1 |
IC50 = 193 nM
|
|
|
|
CP0450083
|
(3S,5R,8R,9R,10R,12R,13R,14R,17R)-3,12-dihydroxy-17-methoxy-4,4,8,10,14-pentamethyl-1,2,3,5,6,7,9,11,12,13,16,17-dodecahydrocyclopenta[a]phenanthren-15-one
Show/Hide
|
C23H38O4
|
1
|
| 1 |
IC50 = 194.5 nM
|
|
|
|
CP0311769
|
2-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]cycloheptan-1-ol
Show/Hide
|
C20H22ClN3O2
|
1
|
| 1 |
IC50 = 197 nM
|
|
|
|
CP0700654
|
2-(4-chlorophenoxy)-N-(1-hydroxy-2-oxatricyclo[3.3.1.1~3,7~]dec-6-yl)-2-methylpropanamide
Show/Hide
|
C19H24ClNO4
|
1
|
| 1 |
IC50 = 199 nM
|
|
|
|
CP0060298
|
2-adamantyl(piperidin-1-yl)methanone
Show/Hide
|
C16H25NO
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0303511
|
2,5-dichloro-N-propan-2-yl-N-[4-[(2R)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl]benzenesulfonamide
Show/Hide
|
C18H18Cl2F3NO3S
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0289422
|
arylsulfonylpiperazine, 10
Show/Hide
|
C20H24F3N3O2S
|
1
|
| 1 |
IC50 = 201 nM
|
|
|
|
CP0035625
|
2-(4-chloro-2-fluoro-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C21H27ClFNO4S
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0770611
|
2-(4-chloro-phenoxy)-2-methyl-N-[5-(3-methyl-ureidocarbonyl)-adamantan-2-yl]-propionamide
Show/Hide
|
C23H30ClN3O4
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0542309
|
N-(2-adamantyl)-2-[4-(4-chlorophenyl)piperazin-1-yl]acetamide
Show/Hide
|
C22H30ClN3O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0501867
|
1-(3-methoxyphenyl)-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0709767
|
2-(5-Methyl-1,3,4-thiadiazol-2-ylsulfinyl)-1-(4-(trifluoromethyl)-phenyl)ethanone
Show/Hide
|
C12H9F3N2O2S2
|
1
|
| 1 |
IC50 = 215 nM
|
|
|
|
CP0141850
|
N-(5-cyanocyclooctyl)-2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C23H32F3N5O
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0766280
|
4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid
Show/Hide
|
C21H26ClNO4
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0091419
|
3-oxo-1-[(2-phenylphenyl)methylsulfanyl]-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C23H20N2OS
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0351936
|
1,1,1-trifluoro-2-[4-(4-methoxyphenyl)sulfonylphenyl]propan-2-ol
Show/Hide
|
C16H15F3O4S
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0199950
|
N-methyl-N-(thiophen-2-ylmethyl)adamantane-1-carboxamide
Show/Hide
|
C17H23NOS
|
1
|
| 1 |
IC50 = 229 nM
|
|
|
|
CP0221390
|
2-(4-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C20H27ClN2O4S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0284920
|
3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-yl]-4-(5-trifluoromethyl-pyridin-2-yloxymethyl)-pyrrolidin-2-one
Show/Hide
|
C24H29F3N6O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0289289
|
1,1,1-trifluoro-2-[4-(4-nitrophenyl)sulfonylphenyl]propan-2-ol
Show/Hide
|
C15H12F3NO5S
|
1
|
| 1 |
IC50 = 233 nM
|
|
|
|
CP0350973
|
1,1,1-trifluoro-2-[4-(4-fluorophenyl)sulfonylphenyl]propan-2-ol
Show/Hide
|
C15H12F4O3S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0284372
|
1-[(2-chlorophenyl)methylsulfonyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H15ClN2O3S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0159922
|
arylsulfonylpiperazine, 22
Show/Hide
|
C16H14Cl2F3N3O2S
|
1
|
| 1 |
IC50 = 241 nM
|
|
|
|
CP0392282
|
[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-17-acetyl-12-acetyloxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
Show/Hide
|
C28H44O5
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
|
CP0194105
|
N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-methyl-2-[6-(methylamino)pyridin-3-yl]propanamide
Show/Hide
|
C22H32N4O2
|
1
|
| 1 |
IC50 = 246 nM
|
|
|
|
CP0315717
|
arylsulfonylpiperazine, 33
Show/Hide
|
C20H25N3O4S
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0413751
|
N-(furan-2-ylmethyl)-N-methyladamantane-1-carboxamide
Show/Hide
|
C17H23NO2
|
1
|
| 1 |
IC50 = 249 nM
|
|
|
|
CP0406051
|
3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylthio)butan-2-one
Show/Hide
|
C14H17N3OS
|
1
|
| 1 |
IC50 = 252 nM
|
|
|
|
CP0493642
|
1-phenyl-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
|
C16H13N3OS
|
1
|
| 1 |
IC50 = 257 nM
|
|
|
|
CP0194198
|
N-(2-adamantyl)-2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]acetamide
Show/Hide
|
C22H29N5O
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0173349
|
4-[3,3-dmethyl-2-oxo-4-(5-trifluoromethyl-pyridin-2-yloxymethyl)-pyrrolidin-1-yl]-N-hydroxy-adamantane-1-carboxamidine
Show/Hide
|
C24H31F3N4O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0709760
|
1-(4-Fluorophenyl)-2-(5-methyl-1,3,4-thiadiazol-2-ylthio)ethanone
Show/Hide
|
C11H9FN2OS2
|
1
|
| 1 |
IC50 = 266 nM
|
|
|
|
CP0210675
|
4-bromo-1-[(2-chlorophenyl)methylsulfanyl]-5,6,7,8-tetrahydro-2H-isoquinolin-3-one
Show/Hide
|
C16H15BrClNOS
|
1
|
| 1 |
IC50 = 269 nM
|
|
|
|
CP0335642
|
8-[(2-cyanopyridin-3-yl)methylsulfanyl]-6-oxo-1,3,4,7-tetrahydropyrano[3,4-c]pyridine-5-carbonitrile
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0433678
|
N-methyl-N-[(3-methylthiophen-2-yl)methyl]adamantane-1-carboxamide
Show/Hide
|
C18H25NOS
|
1
|
| 1 |
IC50 = 275 nM
|
|
|
|
CP0206286
|
4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclopentanecarbonyl}-amino)-adamantane-1-carboxylic acid
Show/Hide
|
C27H35F3N4O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0062330
|
(4-amino-3,5-dichlorophenyl)(3-benzyl-3,6-diaza-bicyclo[3.2.1]octan-6-yl)methanone
Show/Hide
|
C20H21Cl2N3O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0343526
|
2-[4-(2-tert-butylphenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C19H21F3O3S
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0078218
|
N-methyl-1-(4-methylphenyl)-N-(thiophen-2-ylmethyl)cyclopropane-1-carboxamide
Show/Hide
|
C17H19NOS
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0473133
|
1-phenyl-3-(1-phenyl-1H-tetrazol-5-ylthio)propan-2-one
Show/Hide
|
C17H15N3OS
|
1
|
| 1 |
IC50 = 289 nM
|
|
|
|
CP0095259
|
N-cyclohexyl-N-ethyl-2-(4,5,7,8-tetrahydro-[1,2]oxazolo[3,4-d]azepin-6-yl)acetamide
Show/Hide
|
C17H27N3O2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0709762
|
1-(4-Bromophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)sulfinyl)-ethanone
Show/Hide
|
C11H9BrN2O2S2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0345522
|
4-[3-chloro-4-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylphenyl]benzonitrile
Show/Hide
|
C22H15ClF3NO3S
|
1
|
| 1 |
IC50 = 294 nM
|
|
|
|
CP0221389
|
N-[5-(2-amino-2-oxoethyl)sulfonyl-2-adamantyl]-2-(2-chloro-4-fluorophenoxy)-2-methylpropanamide
Show/Hide
|
C22H28ClFN2O5S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0704324
|
4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid 4-sulfamoyl-benzylamide
Show/Hide
|
C28H34ClN3O5S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0401692
|
3-(1-(3-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 304 nM
|
|
|
|
CP0340511
|
CHEMBL219575
Show/Hide
|
C24H27ClN4O3
|
1
|
| 1 |
IC50 = 306 nM
|
|
|
|
CP0120584
|
2-(1-adamantyl)-N-methyl-N-(thiophen-2-ylmethyl)acetamide
Show/Hide
|
C18H25NOS
|
1
|
| 1 |
IC50 = 308 nM
|
|
|
|
CP0766282
|
4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid 4-methanesulfonylaminocarbonyl-benzylamide
Show/Hide
|
C30H36ClN3O6S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0475314
|
1-(3-chlorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C17H14ClN3O
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0314761
|
2-chloro-N-(2,2,2-trifluoroethyl)-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C17H14ClF6NO3S
|
2
|
| 1 |
IC50 = 313 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0240957
|
arylsulfonylpiperazine, 38
Show/Hide
|
C21H26F3N3O2S
|
1
|
| 1 |
IC50 = 315 nM
|
|
|
|
CP0493084
|
N-[4-(carbamoylmethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C21H27F3N2O3
|
2
|
| 1 |
IC50 = 315 nM
|
|
|
| 2 |
IC50 = 1190 nM
|
|
|
|
CP0270136
|
2-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylbenzonitrile
Show/Hide
|
C16H12F3NO3S
|
1
|
| 1 |
IC50 = 315 nM
|
|
|
|
CP0180620
|
2-[4-(3-chlorophenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C15H12ClF3O3S
|
1
|
| 1 |
IC50 = 317 nM
|
|
|
|
CP0035630
|
2-(3-chloro-phenoxy)-2-methyl-N-(5-sulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C20H27ClN2O4S
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0709766
|
1-(4-Chlorophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)sulfinyl)-ethanone
Show/Hide
|
C11H9ClN2O2S2
|
1
|
| 1 |
IC50 = 326 nM
|
|
|
|
CP0062323
|
4-amino-3,5-dichloro-N-[4-(cyclohexylmethylcarbamoyl)cyclohexyl]-N-cyclopropylbenzamide
Show/Hide
|
C24H33Cl2N3O2
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0169237
|
1-[(2-chlorophenyl)methylsulfanyl]-7-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H10ClFN2OS
|
1
|
| 1 |
IC50 = 332 nM
|
|
|
|
CP0716080
|
1-(3-Methoxyphenyl)-2-(5-methyl-1,3,4-thiadiazol-2-ylsulfinyl)-ethanone
Show/Hide
|
C12H12N2O3S2
|
1
|
| 1 |
IC50 = 332 nM
|
|
|
|
CP0453917
|
2-(1-adamantyl)-N-methyl-N-(thiophen-3-ylmethyl)acetamide
Show/Hide
|
C18H25NOS
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0345521
|
2-[4-(benzenesulfonyl)phenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C15H13F3O3S
|
1
|
| 1 |
IC50 = 355 nM
|
|
|
|
CP0475313
|
1-phenyl-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C17H15N3O
|
1
|
| 1 |
IC50 = 359 nM
|
|
|
|
CP0343619
|
ethyl 2-[(3S,5R)-4-(4-amino-3,5-dichlorobenzoyl)-3,5-dimethylpiperazin-1-yl]pyridine-3-carboxylate
Show/Hide
|
C21H24Cl2N4O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0311781
|
4-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]-1-methylcyclohexan-1-ol
Show/Hide
|
C20H22ClN3O2
|
1
|
| 1 |
IC50 = 367 nM
|
|
|
|
CP0141090
|
(4-amino-3,5-dichlorophenyl)((2R,6S)-4-(3-aminopyridin-2-yl)-2,6-dimethylpiperazin-1-yl)methanone
Show/Hide
|
C18H21Cl2N5O
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0137355
|
N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-(5-cyanopyridin-2-yl)oxy-2-methylpropanamide
Show/Hide
|
C22H28N4O3
|
1
|
| 1 |
IC50 = 373 nM
|
|
|
|
CP0291162
|
(R)-3'-(2-fluoroethyl)-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile
Show/Hide
|
C24H19F4NO3S
|
1
|
| 1 |
IC50 = 376 nM
|
|
|
|
CP0381366
|
N-(2-pyridin-2-ylethyl)adamantane-1-carboxamide
Show/Hide
|
C18H24N2O
|
1
|
| 1 |
IC50 = 379 nM
|
|
|
|
CP0062303
|
3-((2R,4R)-1-(4-amino-3,5-dichlorobenzoyl)-2-methylpiperidin-4-yl)benzo[d]oxazol-2(3H)-one
Show/Hide
|
C20H19Cl2N3O3
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0455193
|
1-(4-chlorophenyl)-N-methyl-N-(thiophen-2-ylmethyl)cyclobutane-1-carboxamide
Show/Hide
|
C17H18ClNOS
|
1
|
| 1 |
IC50 = 385 nM
|
|
|
|
CP0036388
|
1-piperidin-1-yl-cyclopropanecarboxylic acid (5-hydroxy-adamantan-2-yl)-amide
Show/Hide
|
C19H30N2O2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0415339
|
(3S,5R,8R,9R,10R,12R,13R,14R)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-1,2,3,5,6,7,9,11,12,13-decahydrocyclopenta[a]phenanthren-15-one
Show/Hide
|
C22H34O3
|
1
|
| 1 |
IC50 = 395.2 nM
|
|
|
|
CP0323516
|
1-[(2-chlorophenyl)methoxy]-7-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C17H10ClFN2O2
|
1
|
| 1 |
IC50 = 396 nM
|
|
|
|
CP0673477
|
1-(4-Methoxyphenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)-sulfonyl)ethanone
Show/Hide
|
C12H12N2O4S2
|
1
|
| 1 |
IC50 = 401 nM
|
|
|
|
CP0339008
|
N-(thiophen-2-ylmethyl)adamantane-1-carboxamide
Show/Hide
|
C16H21NOS
|
1
|
| 1 |
IC50 = 403 nM
|
|
|
|
CP0035633
|
2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C21H28ClNO4S
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0433448
|
4-((5R,10S,13R,14R)-3-acetoxy-4,4,10,13,14-pentamethyl-7,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
Show/Hide
|
C29H42O6
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0497457
|
4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohexylbenzamide
Show/Hide
|
C20H23ClN2O3S
|
1
|
| 1 |
IC50 = 411 nM
|
|
|
|
CP0112295
|
2-phenyl-N-(5-sulfamoyl-adamantan-2-yl)-isobutyramide
Show/Hide
|
C20H28N2O3S
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0493647
|
3-(1-(4-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
|
C18H17N3O2
|
1
|
| 1 |
IC50 = 426 nM
|
|
|
|
CP0532107
|
N-(5,7-dihydroxy-2-adamantyl)-2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C24H33F3N4O3
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0045208
|
4-(2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanamido)bicyclo[2.2.2]octane-1-carboxamide
Show/Hide
|
C23H32F3N5O2
|
1
|
| 1 |
IC50 = 442 nM
|
|
|
|
CP0077766
|
N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-methyl-2-(5-morpholin-4-ylpyridin-2-yl)oxypropanamide
Show/Hide
|
C25H36N4O4
|
1
|
| 1 |
IC50 = 444 nM
|
|
|
|
CP0456740
|
N-methyl-N-(2-thiophen-2-ylethyl)adamantane-1-carboxamide
Show/Hide
|
C18H25NOS
|
1
|
| 1 |
IC50 = 448 nM
|
|
|
|
CP0045210
|
4-(2-(4-chlorophenoxy)-2-methylpropanamido)bicyclo[2.2.2]octane-1-carboxamide
Show/Hide
|
C19H25ClN2O3
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0112294
|
2-(2-chloro-4-fluoro-phenoxy)-N-(5-ethanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C22H29ClFNO4S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0200216
|
N-(5-fluoro-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
Show/Hide
|
C22H28F4N4O
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0200218
|
(2S)-2-[(3R)-3-fluoropyrrolidin-1-yl]-N-(5-hydroxy-2-adamantyl)propanamide
Show/Hide
|
C17H27FN2O2
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0110245
|
3-{(1R,4S,5R,7S)-4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantan-1-yl}-propionic acid
Show/Hide
|
C23H30ClNO4
|
1
|
| 1 |
IC50 = 455 nM
|
|
|
|
CP0311738
|
1-(4-tert-butylphenyl)sulfonyl-2-chlorobenzene
Show/Hide
|
C16H17ClO2S
|
1
|
| 1 |
IC50 = 455 nM
|
|
|
|
CP0203709
|
arylsulfonylpiperazine, 14
Show/Hide
|
C17H18F3N3O3S
|
1
|
| 1 |
IC50 = 456 nM
|
|
|
|
CP0341358
|
arylsulfonylpiperazine, 1
Show/Hide
|
C17H18F3N3O2S
|
1
|
| 1 |
IC50 = 461 nM
|
|
|
|
CP0276720
|
N-[(1S)-5-(3-amino-1H-1,2,4-triazol-5-yl)-2-adamantyl]-2-(4-chlorophenoxy)-2-methylpropanamide
Show/Hide
|
C22H28ClN5O2
|
1
|
| 1 |
IC50 = 476 nM
|
|
|
|
CP0417689
|
1-(furan-2-yl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
|
C14H11N3O2S
|
1
|
| 1 |
IC50 = 485 nM
|
|
|
|
CP0519326
|
[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-acetyloxy-17-(2-hydroxyacetyl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
Show/Hide
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C28H44O6
|
1
|
| 1 |
IC50 = 488 nM
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CP0052163
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4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclopropanecarbonyl}-amino)-adamantane-1-carboxylic acid amide
Show/Hide
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C25H32F3N5O2
|
1
|
| 1 |
IC50 = 490 nM
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CP0257109
|
ethyl 2-[(3S,5R)-4-(4-amino-3,5-dichlorobenzoyl)-3,5-dimethylpiperazin-1-yl]acetate
Show/Hide
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C17H23Cl2N3O3
|
1
|
| 1 |
IC50 = 490 nM
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CP0463310
|
3-(5-(4-methoxyphenyl)-1H-tetrazol-1-yl)-1-phenylpropan-1-one
Show/Hide
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C17H16N4O2
|
1
|
| 1 |
IC50 = 493 nM
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CP0035846
|
[4-(2-hydroxyethyl)piperazin-1-yl]-[3-(4-methylphenyl)-1-adamantyl]methanone
Show/Hide
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C24H34N2O2
|
1
|
| 1 |
IC50 = 498 nM
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CP0172611
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(3R,5R)-adamantan-1-yl(pyrrolidin-1-yl)methanone
Show/Hide
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C15H23NO
|
1
|
| 1 |
IC50 = 498 nM
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CP0303510
|
N-[4-chloro-3-[propan-2-yl-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]phenyl]acetamide
Show/Hide
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C20H22ClF3N2O4S
|
2
|
| 1 |
IC50 = 498 nM
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| 2 |
IC50 > 1000 nM
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CP0035634
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2-(2-chloro-4-fluoro-phenoxy)-2-methyl-N-[5-(3-morpholin-4-yl-propane-1-sulfonyl)-adamantan-2-yl]-propionamide
Show/Hide
|
C27H38ClFN2O5S
|
1
|
| 1 |
IC50 = 500 nM
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CP0173347
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34-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethyl-2-oxopyrrolidin-1-yl)bicyclo[2.2.2]octane-1-carboxamide
Show/Hide
|
C22H28N4O3
|
1
|
| 1 |
IC50 = 500 nM
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CP0378937
|
(3beta,18beta,20beta)-N-Hydroxy-N-methyl-[3-(1,2,4-oxadiazole-5(2H)-one)]-11-oxo-olean-12-en-29-amide
Show/Hide
|
C33H49N3O6
|
1
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| 1 |
IC50 = 504 nM
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CP0414927
|
(R)-4-((1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)cyclopropyl)methyl)morpholine
Show/Hide
|
C26H36N4O3S
|
1
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| 1 |
IC50 = 505 nM
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CP0475315
|
1-cyclohexyl-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
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C16H20N4O
|
1
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| 1 |
IC50 = 506 nM
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CP0162639
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(3s,9s)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethyl-2-oxopyrrolidin-1-yl)bicyclo[3.3.1]nonane-3-carboxamide
Show/Hide
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C23H30N4O3
|
1
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| 1 |
IC50 = 510 nM
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CP0157644
|
arylsulfonylpiperazine, 7
Show/Hide
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C18H20F3N3O2S
|
1
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| 1 |
IC50 = 510 nM
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CP0173432
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(1R,7S,8r)-ethyl 4-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-dimethyl-2-oxopyrrolidin-1-yl)bicyclo[5.1.0]octane-8-carboxylate
Show/Hide
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C24H31N3O4
|
1
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| 1 |
IC50 = 518 nM
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CP0318464
|
arylsulfonylpiperazine, 12
Show/Hide
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C16H15ClF3N3O2S
|
1
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| 1 |
IC50 = 518 nM
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CP0202491
|
arylsulfonylpiperazine, 46
Show/Hide
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C21H27N3O4S
|
1
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| 1 |
IC50 = 527 nM
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CP0136130
|
2-(3-chloro-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
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C21H28ClNO4S
|
1
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| 1 |
IC50 = 530 nM
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CP0203747
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2-(4-chloro-phenoxy)-2-methyl-N-[(1R,2S,5S,7S)-5-(5-oxo-4,5-dihydro-[1,2,4]oxadiazol-3-yl)-adamantan-2-yl]-propionamide
Show/Hide
|
C22H26ClN3O4
|
1
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| 1 |
IC50 = 532 nM
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CP0504269
|
1-(4-dichlorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
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C17H14ClN3O
|
1
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| 1 |
IC50 = 539 nM
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CP0350386
|
8-(3-chloro-2-methylphenoxy)-3-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]pyridine
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C18H18ClN3O2
|
1
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| 1 |
IC50 = 544 nM
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CP0314760
|
2-methylsulfonyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
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C19H22F3NO5S2
|
2
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| 1 |
IC50 = 548 nM
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| 2 |
IC50 > 1000 nM
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CP0045321
|
N-(5-fluoro-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
Show/Hide
|
C22H28F4N4O
|
1
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| 1 |
IC50 = 550 nM
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CP0157643
|
arylsulfonylpiperazine, 9
Show/Hide
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C19H22F3N3O2S
|
1
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| 1 |
IC50 = 556 nM
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CP0035627
|
2-(4-chloro-phenoxy)-N-(5-dimethylsulfamoyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C22H31ClN2O4S
|
1
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| 1 |
IC50 = 560 nM
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CP0202492
|
arylsulfonylpiperazine, 44
Show/Hide
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C21H26F3N3O2S
|
1
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| 1 |
IC50 = 569 nM
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CP0109258
|
arylsulfonylpiperazine, 6
Show/Hide
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C17H18F3N3O2S
|
1
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| 1 |
IC50 = 574 nM
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CP0373462
|
3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
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C17H14ClN3O
|
1
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| 1 |
IC50 = 575 nM
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CP0673479
|
1-(4-Fluorophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)sulfinyl)-ethanone
Show/Hide
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C11H9FN2O2S2
|
1
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| 1 |
IC50 = 576 nM
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CP0528763
|
3-cycloheptyl-8-[(2,6-dichlorophenyl)methoxy]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C20H21Cl2N3O
|
1
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| 1 |
IC50 = 578 nM
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CP0035626
|
2-methyl-2-phenoxy-N-(5-sulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C20H28N2O4S
|
1
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| 1 |
IC50 = 580 nM
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CP0755426
|
2-(5-Methyl-1,3,4-thiadiazol-2-ylsulfinyl)-1-(4-nitrophenyl)-ethanone
Show/Hide
|
C11H9N3O4S2
|
1
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| 1 |
IC50 = 582 nM
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CP0501859
|
1-phenyl-3-(1-p-tolyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C18H17N3O
|
1
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| 1 |
IC50 = 588 nM
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CP0473139
|
1-(3-fluorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C17H14FN3O
|
1
|
| 1 |
IC50 = 597 nM
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CP0187123
|
(4-ethyl-piperazin-1-yl)-[3-(4-methoxy-phenyl)-adamantan-1-yl]-methanone
Show/Hide
|
C24H34N2O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
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CP0318431
|
arylsulfonylpiperazine, 17
Show/Hide
|
C22H20F3N3O2S
|
1
|
| 1 |
IC50 = 603 nM
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CP0118230
|
(3r,9r)-9-(2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanamido)bicyclo[3.3.1]nonane-3-carboxylic acid
Show/Hide
|
C24H33F3N4O3
|
1
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| 1 |
IC50 = 606 nM
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CP0136460
|
arylsulfonylpiperazine, 8
Show/Hide
|
C19H22F3N3O2S
|
1
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| 1 |
IC50 = 613 nM
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CP0051196
|
(18beta,20beta)-3,11-Dioxo-olean-12-en-29-oic acid
Show/Hide
|
C30H44O4
|
1
|
| 1 |
IC50 = 619 nM
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CP0136125
|
2-(4-chloro-phenoxy)-2-methyl-N-(5-methylsulfamoyl-adamantan-2-yl)-propionamide
Show/Hide
|
C21H29ClN2O4S
|
1
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| 1 |
IC50 = 620 nM
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CP0147270
|
2-chloro-N-phenyl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
Show/Hide
|
C21H17ClF3NO3S
|
1
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| 1 |
IC50 = 620 nM
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CP0379552
|
(3beta,18beta,20beta)-3-Acetoxy-N-hydroxy-11-oxo-olean-12-en-29-amide
Show/Hide
|
C32H49NO5
|
1
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| 1 |
IC50 = 626 nM
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CP0761781
|
1-(4-Methoxyphenyl)-2-(5-methyl-1,3,4-thiadiazol-2-ylthio)-ethanone
Show/Hide
|
C12H12N2O2S2
|
1
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| 1 |
IC50 = 628 nM
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CP0677424
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1-Oxo-2-pyridin-3-yl-hexahydro-1lambda*4*-thiopyran-2-carbothioic acid methylamide
Show/Hide
|
C21H30O3
|
1
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| 1 |
IC50 = 630 nM
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CP0308960
|
arylsulfonylpiperazine, 39
Show/Hide
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C21H26F3N3O2S
|
1
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| 1 |
IC50 = 632 nM
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CP0282838
|
(1R,7S)-1,3,10,10-tetramethyl-4-pyridin-2-yl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C17H21N3O
|
1
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| 1 |
IC50 = 634 nM
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CP0035047
|
2-(4-chlorophenoxy)-N-(5-cyanocyclooctyl)-2-methylpropanamide
Show/Hide
|
C19H25ClN2O2
|
1
|
| 1 |
IC50 = 637 nM
|
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CP0205735
|
arylsulfonylpiperazine, 42
Show/Hide
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C22H28F3N3O2S
|
1
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| 1 |
IC50 = 638 nM
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CP0452571
|
4-[(3-Chlorophenylsulfonamido)methyl]-N-cycloheptyl-N-methylbenzamide
Show/Hide
|
C22H27ClN2O3S
|
1
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| 1 |
IC50 = 638 nM
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CP0154849
|
4-[2-(3,3-difluoro-piperidin-1-yl)-butyrylamino]-adamantane-1-carboxylic acid
Show/Hide
|
C20H30F2N2O3
|
1
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| 1 |
IC50 = 640 nM
|
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CP0297083
|
4-amino-N-((1s,4s)-4-(benzylcarbamoyl)cyclohexyl)-3,5-dichloro-N-cyclopropylbenzamide
Show/Hide
|
C24H27Cl2N3O2
|
1
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| 1 |
IC50 = 640 nM
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CP0912152
|
ethyl 3-((8S,9S,10R,11S,13S,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-11-ylamino)-2-(hydroxyimino)propanoate
Show/Hide
|
C26H38N2O5
|
1
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| 1 |
IC50 = 640 nM
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CP0473900
|
3-Chloro-N-[4-(piperidine-1-carbonyl)benzyl]benzenesulfonamide
Show/Hide
|
C19H21ClN2O3S
|
1
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| 1 |
IC50 = 647 nM
|
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CP0330755
|
1-[[3-chloro-4-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylphenyl]methyl]cyclopropane-1-carboxamide
Show/Hide
|
C20H19ClF3NO4S
|
1
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| 1 |
IC50 = 650 nM
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CP0455195
|
2-(1-adamantyl)-N-methyl-N-[(1-methylpyrrol-2-yl)methyl]acetamide
Show/Hide
|
C19H28N2O
|
1
|
| 1 |
IC50 = 655 nM
|
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CP0118609
|
arylsulfonylpiperazine, 11
Show/Hide
|
C16H15F4N3O2S
|
1
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| 1 |
IC50 = 667 nM
|
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CP0689451
|
{4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantan-1-ylmethoxy}-acetic acid
Show/Hide
|
C23H30ClNO5
|
1
|
| 1 |
IC50 = 670 nM
|
|
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CP0498129
|
Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-amide
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
IC50 = 676 nM
|
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CP0449677
|
N-(2-thiophen-2-ylethyl)adamantane-1-carboxamide
Show/Hide
|
C17H23NOS
|
1
|
| 1 |
IC50 = 679 nM
|
|
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CP0493641
|
1-phenyl-3-(1-o-tolyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
IC50 = 683 nM
|
|
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CP0469747
|
4-(5-(3-oxo-3-phenylpropyl)-1H-tetrazol-1-yl)benzonitrile
Show/Hide
|
C18H14N4O
|
1
|
| 1 |
IC50 = 686 nM
|
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CP0035632
|
2-(4-fluoro-2-methoxy-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C22H30FNO5S
|
1
|
| 1 |
IC50 = 690 nM
|
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CP0645486
|
4-[2-(4-chloro-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid 4-(1H-tetrazol-5-yl)-benzylamide
Show/Hide
|
C29H33ClN6O3
|
1
|
| 1 |
IC50 = 690 nM
|
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CP0215435
|
1-adamantyl-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C16H26N2O
|
1
|
| 1 |
IC50 = 700 nM
|
|
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CP0407736
|
1-methyl-2-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]benzimidazole
Show/Hide
|
C19H22N4O2S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
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CP0337220
|
arylsulfonylpiperazine, 29
Show/Hide
|
C21H28N2O2S
|
1
|
| 1 |
IC50 = 702 nM
|
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CP0475316
|
3-(5-(benzo[d][1,3]dioxol-5-yl)-1H-tetrazol-1-yl)-1-phenylpropan-1-one
Show/Hide
|
C17H14N4O3
|
1
|
| 1 |
IC50 = 722 nM
|
|
|
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CP0043733
|
arylsulfonylpiperazine, 2
Show/Hide
|
C16H16F3N3O2S
|
1
|
| 1 |
IC50 = 724 nM
|
|
|
|
CP0254468
|
arylsulfonylpiperazine, 13
Show/Hide
|
C17H15F6N3O2S
|
1
|
| 1 |
IC50 = 727 nM
|
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CP0396388
|
[(2S,4aR,4bR,6R,8S,8aR,10aR)-6-hydroxy-1,1,4a,8,8a-pentamethyl-7-oxo-8-(3-oxopentyl)-3,4,4b,5,6,9,10,10a-octahydro-2H-phenanthren-2-yl] acetate
Show/Hide
|
C26H42O5
|
1
|
| 1 |
IC50 = 729 nM
|
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CP0645484
|
2-(2-chloro-phenoxy)-N-(5-methanesulfonylaminocarbonyl-adamantan-2-yl)-2-methyl-propionamide
Show/Hide
|
C22H29ClN2O5S
|
1
|
| 1 |
IC50 = 744 nM
|
|
|
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CP0476434
|
3-(5-(2-methoxyphenyl)-1H-tetrazol-1-yl)-1-phenylpropan-1-one
Show/Hide
|
C17H16N4O2
|
1
|
| 1 |
IC50 = 751 nM
|
|
|
|
CP0157546
|
1-adamantyl-(4-ethylpiperazin-1-yl)methanone
Show/Hide
|
C17H28N2O
|
1
|
| 1 |
IC50 = 756 nM
|
|
|
|
CP0335801
|
arylsulfonylpiperazine, 43
Show/Hide
|
C21H26F3N3O2S
|
1
|
| 1 |
IC50 = 762 nM
|
|
|
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CP0138094
|
(1S,2R,4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid
Show/Hide
|
C30H48O4
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0473137
|
1-phenyl-4-(1-phenyl-1H-tetrazol-5-yl)butan-2-one
Show/Hide
|
C17H16N4O
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0474298
|
(2R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(phenyl(pyridin-4-yl)methyl)piperazine
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
IC50 = 825 nM
|
|
|
|
CP0378934
|
(3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean-12-en-29-oicacid
Show/Hide
|
C32H49NO4
|
1
|
| 1 |
IC50 = 825 nM
|
|
|
|
CP0349472
|
arylsulfonylpiperazine, 32
Show/Hide
|
C20H25N3O4S
|
1
|
| 1 |
IC50 = 839 nM
|
|
|
|
CP0770610
|
4-(2-methyl-2-phenoxy-propionylamino)-adamantane-1-carboxylic acid
Show/Hide
|
C21H27NO4
|
1
|
| 1 |
IC50 = 840 nM
|
|
|
|
CP0501863
|
1-phenyl-3-(5-phenyl-1H-tetrazol-1-yl)propan-1-one
Show/Hide
|
C16H14N4O
|
1
|
| 1 |
IC50 = 843 nM
|
|
|
|
CP0353974
|
3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl(1-adamantyl)methanone
Show/Hide
|
C20H31NO
|
1
|
| 1 |
IC50 = 846 nM
|
|
|
|
CP0494597
|
N-[(5-hydroxy-1,3,3-trimethylcyclohexyl)methyl]dibenzofuran-2-sulfonamide
Show/Hide
|
C22H27NO4S
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0463302
|
2-(1-benzyl-1H-tetrazol-5-ylthio)-1-(3,4-dimethoxyphenyl)ethanone
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C19H19N3O3S
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1
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| 1 |
IC50 = 860 nM
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CP0114442
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1-(4-chlorophenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanone
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C11H9ClN2OS2
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1
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| 1 |
IC50 = 877 nM
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CP0890150
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(R)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthiazol-4(5H)-one
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C13H20N2OS
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1
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| 1 |
IC50 = 885 nM
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CP0161088
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(1s,4s)-ethyl 4-(4-amino-3,5-dichloro-N-cyclopropylbenzamido)cyclohexanecarboxylate
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C19H24Cl2N2O3
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1
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| 1 |
IC50 = 900 nM
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CP0502306
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3-(1-cyclohexyl-1H-tetrazol-5-yl)-1-phenylpropan-1-one
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C17H21N3O
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1
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| 1 |
IC50 = 915 nM
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CP0256567
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arylsulfonylpiperazine, 15
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C16H15F3N4O4S
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1
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| 1 |
IC50 = 922 nM
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CP0374726
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(3beta,18beta,20beta)-3-Hydroxy-N-methoxy-11-oxo-olean-12-en-29-amide
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C31H49NO4
|
1
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| 1 |
IC50 = 929 nM
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CP0890151
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(S)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthiazol-4(5H)-one
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C13H20N2OS
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1
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| 1 |
IC50 = 931 nM
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CP0311780
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8-(3-chloro-2-methylphenoxy)-3-(4,4-difluorocyclohexyl)-[1,2,4]triazolo[4,3-a]pyridine
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C19H18ClF2N3O
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1
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| 1 |
IC50 = 939 nM
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CP0401691
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3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylsulfonyl)butan-2-one
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C14H17N3O3S
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1
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| 1 |
IC50 = 943 nM
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CP0505799
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1-phenyl-3-(1-m-tolyl-1H-tetrazol-5-yl)propan-1-one
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C18H17N3O
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1
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| 1 |
IC50 = 948 nM
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CP0401688
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1-(3,4-dimethoxyphenyl)-2-(1-isopropyl-1H-tetrazol-5-ylthio)ethanone
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C15H19N3O3S
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1
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| 1 |
IC50 = 954 nM
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CP0141097
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(4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan-1-yl)methanone
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C20H23Cl2N3O
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1
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| 1 |
IC50 = 960 nM
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CP0118603
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arylsulfonylpiperazine, 28
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C21H25F3N2O2S
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1
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| 1 |
IC50 = 971 nM
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CP0506233
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1-phenyl-2-(1-phenyl-1H-tetrazol-5-yloxy)ethanone
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C16H13N3O2
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1
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| 1 |
IC50 = 971 nM
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CP0205690
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arylsulfonylpiperazine, 16
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C17H15F3N4O2S
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1
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| 1 |
IC50 = 978 nM
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CP0399849
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ethyl 5-[(2,5-dimethylphenyl)sulfonylamino]-2-propyl-1-benzofuran-3-carboxylate
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C22H25NO5S
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1
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| 1 |
IC50 = 980 nM
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CP0504267
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1-phenyl-5-(1-phenyl-1H-tetrazol-5-yl)pentan-3-one
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C18H18N4O
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1
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| 1 |
IC50 = 987 nM
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CP0522113
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3-(1-cyclopentyl-1H-tetrazol-5-yl)-1-phenylpropan-1-one
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C16H19N3O
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1
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| 1 |
IC50 = 987 nM
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CP0392285
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[(3S,5R,8R,9R,10R,12R,13S,14R,17S)-12,17-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
Show/Hide
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C24H40O4
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1
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| 1 |
IC50 = 994 nM
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CP0335796
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(3-benzyl-adamantan-1-yl)-(4-ethyl-piperazin-1-yl)-methanone
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C24H34N2O
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1
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| 1 |
IC50 = 1000 nM
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CP0373457
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1-(3,4-dimethoxyphenyl)-2-(1-(2,4-dimethylphenyl)-1H-tetrazol-5-ylthio)ethanone
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C20H21N3O3S
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1
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| 1 |
IC50 = 1000 nM
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CP0373256
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(3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy-11-oxoolean-12-en-29-amide
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C33H51NO5
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2
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| 1 |
IC50 = 1010 nM
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| 2 |
IC50 = 1012 nM
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CP0433446
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(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
Show/Hide
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C30H47NO3
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1
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| 1 |
IC50 = 1020 nM
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CP0709761
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N-(4-(2-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)acetyl)phenyl)-acetamide
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C13H13N3O2S2
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1
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| 1 |
IC50 = 1031 nM
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CP0417685
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2-(1-(4-chlorophenyl)-1H-tetrazol-5-ylthio)-1-(3,4-dimethoxyphenyl)ethanone
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C18H16ClN3O3S
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1
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| 1 |
IC50 = 1040 nM
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CP0396390
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(3S,5R,8R,9R,10R,14S)-3-hydroxy-4,4,8,10,14-pentamethyl-1,2,3,5,6,7,9,11,15,16-decahydrocyclopenta[a]phenanthren-12-one
Show/Hide
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C22H34O2
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1
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| 1 |
IC50 = 1047 nM
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CP0373458
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1-(4-methoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C17H15N3O2S
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1
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| 1 |
IC50 = 1050 nM
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CP0413750
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N-methyl-N-(thiophen-2-ylmethyl)tricyclo[3.3.1.03,7]nonane-3-carboxamide
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C16H21NOS
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1
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| 1 |
IC50 = 1080 nM
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CP0875698
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N'-(2,4-dihydroxy-6-methylbenzylidene)-2-(m-tolyloxy)acetohydrazide
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C17H18N2O4
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1
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| 1 |
IC50 = 1090 nM
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CP0467420
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1-phenyl-3-(1-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-tetrazol-5-yl)propan-1-one
Show/Hide
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C21H21N3O
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1
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| 1 |
IC50 = 1100 nM
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CP0501865
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3-(5-(3-chlorophenyl)-1H-tetrazol-1-yl)-1-phenylpropan-1-one
Show/Hide
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C16H13ClN4O
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1
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| 1 |
IC50 = 1100 nM
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CP0518779
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1-phenyl-3-(5-(thiophen-3-yl)-1H-tetrazol-1-yl)propan-1-one
Show/Hide
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C15H13N3OS
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1
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| 1 |
IC50 = 1100 nM
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CP0132715
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2-[(2-chlorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
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C18H12ClN3OS
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1
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| 1 |
IC50 = 1102 nM
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CP0180621
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1,1,1-trifluoro-2-[4-(2-propan-2-ylphenyl)sulfonylphenyl]propan-2-ol
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C18H19F3O3S
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1
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| 1 |
IC50 = 1120 nM
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CP0496190
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2-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-carbonyl]benzyl}benzenesulfonmide
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C20H23ClN2O4S
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1
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| 1 |
IC50 = 1130 nM
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CP0505543
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(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamide
Show/Hide
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C30H47NO4
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1
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| 1 |
IC50 = 1157 nM
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CP0422544
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11BETA-HYDROXYPROGESTERONE
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C21H30O3
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1
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| 1 |
IC50 = 1160 nM
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CP0496191
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N-[[4-[(2S,6R)-2,6-dimethylmorpholine-4-carbonyl]phenyl]methyl]-3-(trifluoromethyl)benzenesulfonamide
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C21H23F3N2O4S
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1
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| 1 |
IC50 = 1208 nM
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CP0673504
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1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-(5-methyl-1,3,4-thiadiazol-2-ylthio)ethanone
Show/Hide
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C13H12N2O3S2
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1
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| 1 |
IC50 = 1215 nM
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CP0489427
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3,3-dimethyl-1-(1-phenyl-1H-tetrazol-5-ylsulfinyl)butan-2-one
Show/Hide
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C14H17N3O2S
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1
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| 1 |
IC50 = 1230 nM
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CP0534662
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2-[3-[1-(4-chlorophenyl)cyclopropyl]-[1,2,4]triazolo[4,3-a]pyridin-8-yl]-2-methylpropanoic acid
Show/Hide
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C19H18ClN3O2
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1
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| 1 |
IC50 = 1280 nM
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CP0313792
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4-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]bicyclo[2.2.2]octan-1-amine
Show/Hide
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C21H23ClN4O
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1
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| 1 |
IC50 = 1298 nM
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CP0475312
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1-(4-fluorophenyl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C16H12FN3OS
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1
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| 1 |
IC50 = 1300 nM
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CP0417686
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1-(3-fluorophenyl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C16H12FN3OS
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1
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| 1 |
IC50 = 1340 nM
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CP0423164
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3-acetyl-11-keto-ursolic acid
Show/Hide
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C32H48O5
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1
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| 1 |
IC50 = 1350 nM
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CP0463303
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1-(3,4-dimethoxyphenyl)-2-(1-o-tolyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C19H19N3O3S
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1
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| 1 |
IC50 = 1450 nM
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CP0309355
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1-adamantyl-[4-(2-hydroxyethyl)piperazin-1-yl]methanone
Show/Hide
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C17H28N2O2
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1
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| 1 |
IC50 = 1470 nM
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CP0335794
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(4-benzyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
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C29H36N2O
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1
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| 1 |
IC50 = 1500 nM
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CP0514604
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3-(1-(2,3-dihydro-1H-inden-1-yl)-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
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C19H18N4O
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1
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| 1 |
IC50 = 1500 nM
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CP0919464
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3-[1-(1-adamantyl)-1H-tetrazol-5-yl]-1-phenylpropan-1-one
Show/Hide
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C21H25N3O
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1
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| 1 |
IC50 = 1500 nM
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CP0930871
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(R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthiazol-4(5H)-one
Show/Hide
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C13H20N2OS
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1
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| 1 |
IC50 = 1505 nM
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CP0402591
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(2S,4aS,6aS,6bR,8aR,12aS,12bR,14bR,E)-10-(methoxyimino)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
Show/Hide
|
C31H47NO4
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1
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| 1 |
IC50 = 1508 nM
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CP0455194
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1-(4-chlorophenyl)-N-methyl-N-(thiophen-2-ylmethyl)cyclopropane-1-carboxamide
Show/Hide
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C16H16ClNOS
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1
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| 1 |
IC50 = 1550 nM
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CP0417687
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1-(3-methoxyphenyl)-2-(1-phenyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C17H15N3O2S
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1
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| 1 |
IC50 = 1600 nM
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CP0504266
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1-(3,4-dimethoxyphenyl)-2-(1-(2-methoxyphenyl)-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C19H19N3O4S
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1
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| 1 |
IC50 = 1600 nM
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CP0473132
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2-(1-tert-butyl-1H-tetrazol-5-ylthio)-1-(3,4-dimethoxyphenyl)ethanone
Show/Hide
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C16H21N3O3S
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1
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| 1 |
IC50 = 1660 nM
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CP0457469
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3-chloro-N-(4-((2R,6S)-2,6-dimethylmorpholine-4-carbonyl)benzyl)benzenesulfonamide
Show/Hide
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C20H23ClN2O4S
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1
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| 1 |
IC50 = 1672 nM
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CP0463301
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2-(1-phenyl-1H-tetrazol-5-ylthio)-1-(thiophen-2-yl)ethanone
Show/Hide
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C14H11N3OS2
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1
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| 1 |
IC50 = 1700 nM
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CP0473134
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1-(3,4-dimethoxyphenyl)-2-(1-(thiophen-2-ylmethyl)-1H-tetrazol-5-ylthio)ethanone
Show/Hide
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C17H17N3O3S2
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1
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| 1 |
IC50 = 1700 nM
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CP0392283
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N-[(1-methylpyrrol-2-yl)methyl]adamantane-1-carboxamide
Show/Hide
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C17H24N2O
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1
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| 1 |
IC50 = 1700 nM
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CP0875696
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4-(benzofuran-2-carbonyl)-5-(2-fluorophenyl)-3-hydroxy-1-(5-(4-methylbenzylthio)-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one
Show/Hide
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C29H20FN3O4S2
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1
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| 1 |
IC50 = 1730 nM
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CP0497456
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3-Chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benzenesulfonamide
Show/Hide
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C18H19ClN2O3S
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1
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| 1 |
IC50 = 1733 nM
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CP0102625
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4-{2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-butyrylamino}-adamantane-1-carboxylic acid
Show/Hide
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C25H33F3N4O3
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1
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| 1 |
IC50 = 1800 nM
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CP0506235
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3-(5-(2-chlorophenyl)-1H-tetrazol-1-yl)-1-phenylpropan-1-one
Show/Hide
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C17H14ClN3O
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1
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| 1 |
IC50 = 1800 nM
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CP0191621
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1-adamantyl(3,4-dihydro-2H-quinolin-1-yl)methanone
Show/Hide
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C20H25NO
|
1
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| 1 |
IC50 = 1860 nM
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CP0112326
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(4-phenethyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
|
C30H38N2O
|
1
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| 1 |
IC50 = 1900 nM
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CP0036383
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4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-cyclopropanecarbonyl}-amino)-adamantane-1-carboxylic acid
Show/Hide
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C25H31F3N4O3
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1
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| 1 |
IC50 = 1900 nM
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CP0504268
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1-phenyl-3-(5-(pyrazin-2-yl)-1H-tetrazol-1-yl)propan-1-one
Show/Hide
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C14H12N6O
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1
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| 1 |
IC50 = 1900 nM
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CP0040077
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(3beta)-3-hydroxyurs-12-en-28-oic acid
Show/Hide
|
C30H48O3
|
1
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| 1 |
IC50 = 1900 nM
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CP0420089
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1-[(2R,3S)-3-[(1R)-1-[(3R,5R,9R,10R,13S,14S,17S)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]oxiran-2-yl]-2-methylpropane-1,2-diol
Show/Hide
|
C30H50O4
|
1
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| 1 |
IC50 = 1900 nM
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CP0109259
|
benzyl piperazine, 5
Show/Hide
|
C17H18F3N3
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1
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| 1 |
IC50 = 1930 nM
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CP0501869
|
11-keto-ursolic acid
Show/Hide
|
C30H46O4
|
1
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| 1 |
IC50 = 2060 nM
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CP0287737
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[4-(2-methoxyethyl)piperazin-1-yl]-[3-(4-methylphenyl)-1-adamantyl]methanone
Show/Hide
|
C25H36N2O2
|
1
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| 1 |
IC50 = 2100 nM
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CP0449768
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2-[4-[3-(4-methylphenyl)adamantane-1-carbonyl]piperazin-1-yl]-2-phenylacetonitrile
Show/Hide
|
C30H35N3O
|
1
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| 1 |
IC50 = 2100 nM
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CP0439635
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N-(5,7-dihydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C23H31F3N4O3
|
1
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| 1 |
IC50 = 2100 nM
|
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CP0522111
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3-(1-benzyl-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
|
C18H17N3O
|
1
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| 1 |
IC50 = 2100 nM
|
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CP0452569
|
4-[(3-Chlorophenylsulfonamido)methyl]-N,N-diethylbenzamide
Show/Hide
|
C18H21ClN2O3S
|
1
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| 1 |
IC50 = 2106 nM
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CP0502303
|
1-(3,4-dimethoxyphenyl)-2-(1-methyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
|
C13H15N3O3S
|
1
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| 1 |
IC50 = 2180 nM
|
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CP0502304
|
3-(1-(2-methoxyphenyl)-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
|
C18H17N3O2
|
1
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| 1 |
IC50 = 2200 nM
|
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CP0453918
|
1-(4-chlorophenyl)-N-methyl-N-(thiophen-2-ylmethyl)cyclopentane-1-carboxamide
Show/Hide
|
C18H20ClNOS
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0875699
|
2-(4-allyl-5-((phenylamino)methyl)-4H-1,2,4-triazol-3-ylthio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide
Show/Hide
|
C22H23BrN6O2S
|
1
|
| 1 |
IC50 = 2250 nM
|
|
|
|
CP0160723
|
(7r,9r)-9-(2-(4-chlorophenoxy)-2-methylpropanamido)-3-oxa-bicyclo[3.3.1]nonane-7-carboxamide
Show/Hide
|
C19H25ClN2O4
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0501860
|
1-phenyl-3-(1-(tetrahydro-2H-pyran-4-yl)-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C16H19N3O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0311740
|
1,1,1-trifluoro-2-[4-[2-(4-fluorophenyl)phenyl]sulfonylphenyl]propan-2-ol
Show/Hide
|
C21H16F4O3S
|
1
|
| 1 |
IC50 = 2410 nM
|
|
|
|
CP0401689
|
1-(3,4-dimethoxyphenyl)-2-(1-p-tolyl-1H-tetrazol-5-ylthio)ethanone
Show/Hide
|
C19H19N3O3S
|
1
|
| 1 |
IC50 = 2450 nM
|
|
|
|
CP0388344
|
3-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-carbonyl]benzyl}-4-fluorobenzenesulfonamide
Show/Hide
|
C20H22ClFN2O4S
|
1
|
| 1 |
IC50 = 2631 nM
|
|
|
|
CP0505738
|
4-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-carbonyl]benzyl}benzenesulfonmide
Show/Hide
|
C20H23ClN2O4S
|
1
|
| 1 |
IC50 = 2698 nM
|
|
|
|
CP0335643
|
3-oxo-1-phenyl-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 = 2816 nM
|
|
|
|
CP0508189
|
2-(1-adamantyl)-N-[(1-methylpyrrol-2-yl)methyl]acetamide
Show/Hide
|
C18H26N2O
|
1
|
| 1 |
IC50 = 2880 nM
|
|
|
|
CP0397872
|
3-cycloheptyl-8-[(2,6-dichlorophenyl)sulfonylmethyl]-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C20H21Cl2N3O2S
|
1
|
| 1 |
IC50 = 2962 nM
|
|
|
|
CP0458874
|
N-(5-fluoro-7-hydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
Show/Hide
|
C23H30F4N4O2
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0378933
|
(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
Show/Hide
|
C32H48O5
|
3
|
| 1 |
IC50 = 3450 nM
|
|
|
| 2 |
IC50 = 7100 nM
|
|
|
| 3 |
IC50 = 7138 nM
|
|
|
|
CP0493970
|
N,1-dimethyl-N-(thiophen-2-ylmethyl)cyclohexane-1-carboxamide
Show/Hide
|
C14H21NOS
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0066118
|
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
Show/Hide
|
C12H11ClN2O5S
|
1
|
| 1 |
IC50 = 3760 nM
|
|
|
|
CP0433447
|
2-((3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-(methoxycarbonyl)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yloxy)benzoic acid
Show/Hide
|
C38H52O6
|
1
|
| 1 |
IC50 = 3840 nM
|
|
|
|
CP0473136
|
1-phenyl-3-(1-(pyridin-3-yl)-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C15H13N5O
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0501866
|
1-phenyl-3-(5-(pyridin-3-yl)-1H-tetrazol-1-yl)propan-1-one
Show/Hide
|
C15H13N5O
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0432384
|
N-(3-chloro-4-hydroxynaphthalen-1-yl)-2,4-dimethylbenzenesulfonamide
Show/Hide
|
C18H16ClNO3S
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0378935
|
[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-11-(trifluoromethylsulfonylcarbamoylamino)-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl] acetate
Show/Hide
|
C33H49F3N2O6S
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0060300
|
2-adamantan-1-yl-1-(4-ethyl-piperazin-1-yl)-ethanone
Show/Hide
|
C18H30N2O
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0397195
|
2-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]-1-methylbenzimidazole
Show/Hide
|
C19H22N4O3S
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0463306
|
1-phenyl-3-(5-(pyrimidin-2-yl)-1H-tetrazol-1-yl)propan-1-one
Show/Hide
|
C14H12N6O
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0501861
|
1-(4-fluorophenyl)-3-(1-phenyl-1H-tetrazol-5-yl)propan-1-one
Show/Hide
|
C16H13FN4O
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0387317
|
2-[4-(4-tert-butylphenyl)sulfonylpiperazin-1-yl]-1-methylbenzimidazole
Show/Hide
|
C22H28N4O2S
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0373548
|
3-epicorosolic acid methyl ester
Show/Hide
|
C31H50O4
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0455097
|
N-[2-(3,4-dimethoxyphenyl)ethyl]-4,7,7-trimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carboxamide
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
IC50 = 5210 nM
|
|
|
|
CP0445451
|
2-(2,4-dibromophenoxy)-N-(3-(1-hydroxyethyl)phenyl)propanamide
Show/Hide
|
C17H17Br2NO3
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0499058
|
[(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picen-2-yl]urea
Show/Hide
|
C30H48N2O3
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0348940
|
1-adamantyl(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C20H25NO
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0288588
|
methyl 2-[[4-[(4-amino-3,5-dichlorobenzoyl)-cyclopropylamino]cyclohexanecarbonyl]-methylamino]acetate
Show/Hide
|
C21H27Cl2N3O4
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
|
CP0180306
|
4-amino-3,5-dichloro-N-cyclopropyl-N-((1s,4s)-4-(pyrrolidine-1-carbonyl)cyclohexyl)benzamide
Show/Hide
|
C21H27Cl2N3O2
|
1
|
| 1 |
IC50 = 6400 nM
|
|
|
|
CP0395998
|
2-[4-(benzenesulfonyl)piperazin-1-yl]-1-methylbenzimidazole
Show/Hide
|
C18H20N4O2S
|
1
|
| 1 |
IC50 = 6400 nM
|
|
|
|
CP0169240
|
1-[(2-chlorophenyl)methylsulfanyl]-5,6,7,8-tetrahydro-2H-isoquinolin-3-one
Show/Hide
|
C16H16ClNOS
|
1
|
| 1 |
IC50 = 6904 nM
|
|
|
|
CP0136085
|
1-adamantyl-(4-benzylpiperazin-1-yl)methanone
Show/Hide
|
C22H30N2O
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0144337
|
1-(4-ethylpiperazin-1-yl)-2-phenylethanone
Show/Hide
|
C14H20N2O
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0331683
|
1-adamantyl-[4-(pyridin-4-ylmethyl)piperazin-1-yl]methanone
Show/Hide
|
C21H29N3O
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0098981
|
(3-hydroxy-adamantan-1-yl)-piperidin-1-yl-methanone
Show/Hide
|
C16H25NO2
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0144336
|
(4-phenyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
|
C28H34N2O
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0501290
|
(4-phenylmethanesulfonyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
|
C29H36N2O3S
|
1
|
| 1 |
IC50 = 7700 nM
|
|
|
|
CP0311767
|
4-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]cyclohexan-1-one
Show/Hide
|
C19H18ClN3O2
|
1
|
| 1 |
IC50 = 7804 nM
|
|
|
|
CP0867883
|
(E)-N'-(2,4-dihydroxy-6-methylbenzylidene)-2,3-dihydrobenzo[b][1,4]dioxine-2-carbohydrazide
Show/Hide
|
C17H16N2O5
|
1
|
| 1 |
IC50 = 7980 nM
|
|
|
|
CP0522112
|
3-(1-cyclopropyl-1H-tetrazol-5-yl)-1-phenylpropan-1-one
Show/Hide
|
C13H14N4O
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0112327
|
(4-pyridin-4-ylmethyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
|
C28H35N3O
|
1
|
| 1 |
IC50 = 8100 nM
|
|
|
|
CP0340803
|
1-adamantyl(piperazin-1-yl)methanone
Show/Hide
|
C15H24N2O
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0499057
|
(3beta,18beta,20beta)-N-[-3-(Acetoxy)-11-oxo-30-norolean-12-en-20-yl]urea
Show/Hide
|
C32H50N2O4
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0452570
|
4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclopentylbenzamide
Show/Hide
|
C19H21ClN2O3S
|
1
|
| 1 |
IC50 = 8512 nM
|
|
|
|
CP0498736
|
2,6-dichloro-N-(3-cycloheptyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)benzenesulfonamide
Show/Hide
|
C19H20Cl2N4O2S
|
1
|
| 1 |
IC50 = 8778 nM
|
|
|
|
CP0460985
|
methyl (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C31H50O5
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0468891
|
[(1R,2R,4R,6S,7S,9S,10R,11R)-6-(furan-3-yl)-17-hydroxy-1,7,11,15,15-pentamethyl-14,18-dioxo-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadeca-12,16-dien-9-yl] acetate
Show/Hide
|
C28H32O7
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0203733
|
N-[(1S)-5-(2-amino-2-oxoethyl)-2-adamantyl]-2-methyl-2-[5-(4-methylpiperazin-1-yl)pyridin-2-yl]oxypropanamide
Show/Hide
|
C26H39N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0875697
|
4-(4-butoxy-3-methylbenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-5-p-tolyl-1H-pyrrol-2(5H)-one
Show/Hide
|
C29H30N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0911619
|
N-Adamantan-1-yl-3-{[2-(4-bromo-3-methyl-phenoxy)-acetyl]-hydrazono}-butyramide
Show/Hide
|
C23H30BrN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0353975
|
3-methyl-2-[4-(3-p-tolyl-adamantane-1-carbonyl)-piperazin-1-yl]-butyronitrile
Show/Hide
|
C27H37N3O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0352401
|
N-(1-hydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
Show/Hide
|
C22H29F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0173346
|
4-[3,3-dimethyl-2-oxo-4-(5-trifluoromethyl-pyridin-2-yloxymethyl)-pyrrolidin-1-yl]-adamantane-1-carboxamidine
Show/Hide
|
C24H31F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0141102
|
(4-amino-3,5-dichlorophenyl)((2R,6S)-2,6-dimethyl-4-(pyridin-2-yl)piperazin-1-yl)methanone
Show/Hide
|
C18H20Cl2N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0468612
|
4,4-dimethyl-1-(1-phenyl-1H-tetrazol-5-yl)pentan-3-one
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0493650
|
3-(5-(4-chlorophenyl)-1H-tetrazol-1-yl)-1-phenylpropan-1-one
Show/Hide
|
C16H13ClN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0500521
|
[(2S,4aS,6aR,6aS,6bR,8aR,12aS,14bR)-2,4a,6a,6b,9,9,12a-heptamethyl-10,13-dioxo-1,3,4,5,6,6a,7,8,8a,11,12,14b-dodecahydropicen-2-yl]urea
Show/Hide
|
C30H46N2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0098979
|
(4-ethylpiperazin-1-yl)(1-(4-fluorophenyl)cyclopentyl)methanone
Show/Hide
|
C18H25FN2O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0338893
|
1-adamantyl-[4-(2-methoxyethyl)piperazin-1-yl]methanone
Show/Hide
|
C18H30N2O2
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0433445
|
(R)-2-((2S,4aR,6S,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-hydroxy-2,4a,6,6a,6b,9,9,12a,14b-nonamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxamido)-3-phenylpropanoic acid
Show/Hide
|
C41H59NO5
|
1
|
| 1 |
IC50 = 12600 nM
|
|
|
|
CP0458009
|
1-adamantyl-(4-benzylsulfonylpiperazin-1-yl)methanone
Show/Hide
|
C22H30N2O3S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0164283
|
5-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]azepan-2-one
Show/Hide
|
C19H19ClN4O2
|
1
|
| 1 |
IC50 = 14030 nM
|
|
|
|
CP0421997
|
3-Chloro-N-[4-(morpholine-4-carbonyl)benzyl]benzenesulfonamide
Show/Hide
|
C18H19ClN2O4S
|
1
|
| 1 |
IC50 = 14490 nM
|
|
|
|
CP0411086
|
1-(1-phenyl-1H-tetrazol-5-ylthio)propan-2-one
Show/Hide
|
C11H11N3OS
|
1
|
| 1 |
IC50 = 14500 nM
|
|
|
|
CP0060297
|
(4-ethylpiperazin-1-yl)(3-methyl-1H-inden-2-yl)methanone
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0220818
|
CHEMBL373889
Show/Hide
|
C22H29F3N4O2
|
1
|
| 1 |
IC50 > 15000 nM
|
|
|
|
CP0535341
|
3-Chloro-N-[4-(4-methylpiperazine-1-carbonyl)benzyl]benzenesulfonamide
Show/Hide
|
C19H22ClN3O3S
|
1
|
| 1 |
IC50 = 15900 nM
|
|
|
|
CP0345656
|
3-(1-azabicyclo[2.2.2]octan-4-yl)-8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridine
Show/Hide
|
C20H21ClN4O
|
1
|
| 1 |
IC50 = 16060 nM
|
|
|
|
CP0523657
|
2-[4-(3,4-dimethoxyphenyl)sulfonylpiperazin-1-yl]-1-methylbenzimidazole
Show/Hide
|
C20H24N4O4S
|
1
|
| 1 |
IC50 = 18500 nM
|
|
|
|
CP0187120
|
2-[4-(adamantane-1-carbonyl)-piperazin-1-yl]-3-methyl-butyronitrile
Show/Hide
|
C20H31N3O
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0187121
|
(4-tert-butylcyclohexyl)(4-ethylpiperazin-1-yl)methanone
Show/Hide
|
C17H32N2O
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0556620
|
(1R,7S)-4-(2,6-dichlorophenyl)-1,3,10,10-tetramethyl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 > 22000 nM
|
|
|
|
CP0574139
|
(1R,7S)-5-methoxy-1,10,10-trimethyl-4-(4-methylphenyl)-3,4-diazatricyclo[5.2.1.02,6]deca-2,5-diene
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
IC50 > 22000 nM
|
|
|
|
CP0449769
|
2-[4-(adamantane-1-carbonyl)piperazin-1-yl]-2-phenylacetonitrile
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0395999
|
2-[4-(4-methoxy-3-nitrophenyl)sulfonylpiperazin-1-yl]-1-methylbenzimidazole
Show/Hide
|
C19H21N5O5S
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1
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| 1 |
IC50 = 27200 nM
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CP0062305
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4-amino-3,5-dichloro-N-cyclopropyl-N-[4-[2-(dimethylamino)ethylcarbamoyl]cyclohexyl]benzamide
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C21H30Cl2N4O2
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1
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| 1 |
IC50 > 30000 nM
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CP0141094
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4-amino-3,5-dichloro-N-cyclopropyl-N-((1s,4s)-4-(1-methylpiperazine-4-carbonyl)cyclohexyl)benzamide
Show/Hide
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C22H30Cl2N4O2
|
1
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| 1 |
IC50 > 30000 nM
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CP0141104
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2-((1s,4s)-4-(4-amino-3,5-dichloro-N-cyclopropylbenzamido)cyclohexanecarboxamido)acetic acid
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C19H23Cl2N3O4
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1
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| 1 |
IC50 > 30000 nM
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CP0309356
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[4-[3-(4-methylphenyl)adamantane-1-carbonyl]piperazin-1-yl]-phenylmethanone
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C29H34N2O2
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1
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| 1 |
IC50 = 36000 nM
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CP0378936
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1-((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-10-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yloxy)-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicen-2-yl)urea
Show/Hide
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C32H48N4O5
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1
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| 1 |
IC50 > 40000 nM
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CP0513050
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(5aR,7aR,7bS,9aS,12S,13aR,15aR,15bS)-2,3,4,5,5a,6,7,7a,7b,8,9,9a,10,11,12,13,13a,15,15a,15b-Eicosahydro-5,5,7a,7b,9a,12,15b-heptamethyl-3,15-dioxo-N-hydroxy-N-methyl-1Hchryseno[2,1-c]azepine-12-carboxylic acid amid
Show/Hide
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C31H48N2O4
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1
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| 1 |
IC50 > 40000 nM
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CP0098980
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2-bicyclo[2.2.1]heptanyl-(4-ethylpiperazin-1-yl)methanone
Show/Hide
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C14H24N2O
|
1
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| 1 |
IC50 = 44000 nM
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CP0378940
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[(1R,2S,5S,8S,10R,14R,15S,21R)-1,2,5,8,15,20,20-heptamethyl-13,18-dioxo-19-azapentacyclo[12.9.0.02,11.05,10.015,21]tricos-11-en-8-yl]urea
Show/Hide
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C30H47N3O3
|
1
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| 1 |
IC50 = 45000 nM
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|
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CP0287736
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1-adamantyl-[4-(2-phenylethyl)piperazin-1-yl]methanone
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C23H32N2O
|
1
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| 1 |
IC50 = 47000 nM
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|
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CP0052117
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3-cyclohexyl-1-(4-ethylpiperazin-1-yl)propan-1-one
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C15H28N2O
|
1
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| 1 |
IC50 = 48000 nM
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|
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CP0350387
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1-[4-[8-(3-chloro-2-methylphenoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidin-1-yl]ethanone
Show/Hide
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C20H21ClN4O2
|
1
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| 1 |
IC50 = 48240 nM
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|
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CP0897971
|
4-(2,4-dichlorophenyl)-2-hydroxy-3-(4-methoxy-3-methylbenzoyl)-5-(2-methoxyethyl)cyclopent-2-enone
Show/Hide
|
C23H22Cl2O5
|
1
|
| 1 |
IC50 > 50000 nM
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|
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CP0052114
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(4-ethyl-piperazin-1-yl)-(3-hydroxy-adamantan-1-yl)-methanone
Show/Hide
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C17H28N2O2
|
1
|
| 1 |
IC50 = 53000 nM
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|
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CP0335795
|
cyclohexyl-(4-ethylpiperazin-1-yl)methanone
Show/Hide
|
C13H24N2O
|
1
|
| 1 |
IC50 = 53000 nM
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|
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CP0510958
|
(4-benzenesulfonyl-piperazin-1-yl)-(3-p-tolyl-adamantan-1-yl)-methanone
Show/Hide
|
C28H34N2O3S
|
1
|
| 1 |
IC50 = 64000 nM
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|
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CP0098977
|
1-adamantyl-[4-(benzenesulfonyl)piperazin-1-yl]methanone
Show/Hide
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C21H28N2O3S
|
1
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| 1 |
IC50 > 100000 nM
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|
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CP0098978
|
1-adamantyl-(4-phenylpiperazin-1-yl)methanone
Show/Hide
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C21H28N2O
|
1
|
| 1 |
IC50 > 100000 nM
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|
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CP0187122
|
1-(4-ethylpiperazin-1-yl)-2,2-dimethylpropan-1-one
Show/Hide
|
C11H22N2O
|
1
|
| 1 |
IC50 > 100000 nM
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|
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CP0202430
|
2-cyclohexyl-1-(4-ethylpiperazin-1-yl)ethanone
Show/Hide
|
C14H26N2O
|
1
|
| 1 |
IC50 > 100000 nM
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|
|
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CP0287739
|
(4-ethylpiperazin-1-yl)(phenyl)methanone
Show/Hide
|
C13H18N2O
|
1
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| 1 |
IC50 > 100000 nM
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|
|
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CP0338895
|
cyclopropyl-(4-ethylpiperazin-1-yl)methanone
Show/Hide
|
C10H18N2O
|
1
|
| 1 |
IC50 > 100000 nM
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|
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CP0533045
|
[4-(adamantane-1-carbonyl)piperazin-1-yl]-phenylmethanone
Show/Hide
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C22H28N2O2
|
1
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| 1 |
IC50 > 100000 nM
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|
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CP0145673
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1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carboxamide
Show/Hide
|
C17H17ClN2O2S
|
1
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| 1 |
IC50 > 10 nM
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CP0386729
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N-cyclopropyl-N-(4-hydroxy-4-pyridin-3-ylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C24H27F3N2O3
|
1
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| 1 |
IC50 > 300 nM
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CP0486317
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N-cyclopropyl-N-(4-hydroxy-4-phenylcyclohexyl)-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
Show/Hide
|
C25H28F3NO3
|
1
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| 1 |
IC50 > 300 nM
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CP0180622
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2-[4-(4-amino-2-chlorophenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
Show/Hide
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C15H13ClF3NO3S
|
1
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| 1 |
IC50 > 300 nM
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CP0289290
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2-[2-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylphenyl]acetamide
Show/Hide
|
C17H16F3NO4S
|
1
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| 1 |
IC50 > 300 nM
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CP0343527
|
[3-chloro-4-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylphenyl]urea
Show/Hide
|
C16H14ClF3N2O4S
|
1
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| 1 |
IC50 > 300 nM
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CP0350974
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1,1,1-trifluoro-2-[4-[2-(2-hydroxypropan-2-yl)phenyl]sulfonylphenyl]propan-2-ol
Show/Hide
|
C18H19F3O4S
|
1
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| 1 |
IC50 > 300 nM
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CP0350976
|
3-chloro-4-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfonylbenzamide
Show/Hide
|
C16H13ClF3NO4S
|
1
|
| 1 |
IC50 > 300 nM
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|
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CP0091734
|
arylsulfonylpiperazine, 21
Show/Hide
|
C17H15F6N3O2S
|
1
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| 1 |
IC50 > 1000 nM
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|
|
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CP0112404
|
arylsulfonylpiperazine, 35
Show/Hide
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C21H28N2O2S
|
1
|
| 1 |
IC50 > 1000 nM
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|
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CP0112405
|
arylsulfonylpiperazine, 25
Show/Hide
|
C16H18ClN3O2S
|
1
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| 1 |
IC50 > 1000 nM
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|
|
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CP0118604
|
arylsulfonylpiperazine, 40
Show/Hide
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C22H28F3N3O2S
|
1
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| 1 |
IC50 > 1000 nM
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|
|
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CP0118605
|
arylsulfonylpiperazine, 31
Show/Hide
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C20H25FN2O2S
|
1
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| 1 |
IC50 > 1000 nM
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|
|
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CP0118606
|
arylsulfonylpiperazine, 20
Show/Hide
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C16H15ClF3N3O2S
|
1
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| 1 |
IC50 > 1000 nM
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|
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CP0156836
|
arylsulfonylpiperazine, 36
Show/Hide
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C20H25FN2O2S
|
1
|
| 1 |
IC50 > 1000 nM
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|
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CP0159843
|
arylsulfonylpiperazine, 23
Show/Hide
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C16H19N3O2S
|
1
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| 1 |
IC50 > 1000 nM
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|
|
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CP0160034
|
arylsulfonylpiperazine, 34
Show/Hide
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C20H25ClN2O2S
|
1
|
| 1 |
IC50 > 1000 nM
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|
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CP0169093
|
arylsulfonylpiperazine, 30
Show/Hide
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C20H25ClN2O2S
|
1
|
| 1 |
IC50 > 1000 nM
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|
|
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CP0179417
|
arylsulfonylpiperazine, 26
Show/Hide
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C16H18N4O4S
|
1
|
| 1 |
IC50 > 1000 nM
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|
|
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CP0209002
|
arylsulfonylpiperazine, 27
Show/Hide
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C17H18N4O2S
|
1
|
| 1 |
IC50 > 1000 nM
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|
|
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CP0321047
|
phenylcarbonyl piperazine, 3
Show/Hide
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C17H16F3N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0337221
|
arylsulfonylpiperazine, 24
Show/Hide
|
C17H21N3O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0357928
|
arylsulfonylpiperazine, 37
Show/Hide
|
C21H28N2O3S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0433814
|
arylsulfonylpiperazine, 41
Show/Hide
|
C22H28F3N3O2S
|
1
|
| 1 |
IC50 > 1000 nM
|
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|
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CP0270135
|
2,4-dichloro-1-(2-chlorophenyl)sulfonylbenzene
Show/Hide
|
C12H7Cl3O2S
|
1
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| 1 |
IC50 > 3000 nM
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