Brief Information of the Compound and Protein
Compound Name
(3s,9s)-9-(2-(5-cyanopyridin-2-yloxy)-2-methylpropanamido)bicyclo[3.3.1]nonane-3-carboxamide
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Canonical SMILES
CC(C)(Oc1ccc(cn1)C#N)C(=O)N[C@@H]1C2CCCC1C[C@H](C2)C(N)=O
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Compound Formula C20H26N4O3
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11 nM