Brief Information of the Compound and Protein
Compound Name
(2R)-N-(adamantan-2-yl)-1-(3,3,3-trifluoropropyl)pyrrolidine-2-carboxamide
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PubChem ID
CID: 46888840
Canonical SMILES
FC(F)(F)CCN1CCC[C@@H]1C(=O)NC1C2CC3CC(C2)CC1C3
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Compound Formula C18H27F3N2O
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 0.32 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1 nM