Brief Information of the Compound and Protein
Compound Name
(1R,7S)-4-(2-fluorophenyl)-1,10,10-trimethyl-3-propan-2-yl-3,4-diazatricyclo[5.2.1.02,6]dec-2(6)-en-5-one
    Show/Hide
PubChem ID
CID: 16118897
SID: 24766061
Canonical SMILES
CC(C)n1c2c([C@H]3CC[C@]2(C)C3(C)C)c(=O)n1-c1ccccc1F
    Show/Hide
Compound Formula C20H25FN2O
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS