Brief Information of the Compound and Protein
Compound Name
4-[2-(3,3-difluoro-piperidin-1-yl)-butyrylamino]-adamantane-1-carboxylic acid
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Canonical SMILES
CCC(N1CCCC(F)(F)C1)C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(O)=O
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Compound Formula C20H30F2N2O3
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 73 nM