Brief Information of the Compound and Protein
Compound Name
N-cyclohexyl-N-(cyclopropylmethyl)-4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide
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PubChem ID
CID: 15987307
SID: 24266578
Canonical SMILES
CC(O)(c1ccc(cc1)C(=O)N(CC1CC1)C1CCCCC1)C(F)(F)F
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Compound Formula C20H26F3NO2
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
2
IC50 = 849 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM