Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-chloro-5-methyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
    Show/Hide
 PubChem ID
CID: 70688083
Canonical SMILES
CC(C)N(c1ccc(cc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1cc(C)ccc1Cl
    Show/Hide
Compound Formula C19H21ClF3NO3S
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
2
IC50 = 103 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.5 nM